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361
A novel α-conotoxin [D1G, ΔQ14] LvIC decreased mouse locomotor activity
Published 2025-01-01“…This treatment also resulted in reduced expression of neuronal calcium sensor 1 (NCS-1) and neuroligin 3 (NLGN-3) in the prefrontal cortex (PFC), hippocampus (Hip), and caudate putamen (CPu). Both NCS-1 and NLGN-3 are crucial for neuronal development, synapse formation, and neuron activity, and their reduction is associated with decreased synapse strength. …”
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362
Shaoyao Gancao decoction alleviates paclitaxel-induced cognitive impairment by activating PTEN/PI3K/AKT pathway to inhibit NETs formation
Published 2025-02-01“…Furthermore, SGD remarkably reduced IL-1β, TNF-α and microglia activation, while enhanced SOD activity in hippocampus. In addition, SGD could inhibit NETs formation, evidenced by decreasing the level of plasma MPO-DNA complex, as well as MPO and PAD4 expression. …”
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363
Exploring Azithromycin’s Neuroprotective Role in Traumatic Brain Injury: Insights into Cognitive and Motor Recovery and Neuroinflammatory Modulation
Published 2025-01-01“…Histological evaluations focused on neuronal integrity in the cortex, hippocampus, and striatum. Results: Treatment with AZI significantly facilitated motor and cognitive function recovery in TBI-affected rats. …”
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364
Sleep Promotion by 3-Hydroxy-4-Iminobutyric Acid in Walnut Diaphragma juglandis Fructus
Published 2023-01-01“…Subsequently, a metabolomics approach of the serum, basal ganglia, hypothalamus, and hippocampus as well as the gut microbiota was undertaken to unravel the underlying molecular mechanisms of sleep promotion. …”
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365
The role of smell in medical and psychological disorders: An interdisciplinary approach
Published 2019-11-01“…Functional imaging studies showed a reduced activity of the hippocampus and amygdala in response to odourous stimuli in patients with Parkinson’s disease compared with healthy controls. …”
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366
MO-GCN: A multi-omics graph convolutional network for discriminative analysis of schizophrenia
Published 2025-02-01“…Interpretability analysis revealed that the top 10 important brain features were primarily from the hippocampus, olfactory, fusiform and pallidum, which were involved in the brain systems of memory, learning and emotion. …”
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367
Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function
Published 2025-01-01“…Notably, we observed marked changes in CD4+ T cells and eosinophils in the meninges, as well as alterations in glial cell dynamics within the hippocampus and other brain regions. These alterations were characterized by heightened microglial activation, diminished astrocyte reactivity and a shift towards a proinflammatory milieu within the CNS. …”
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368
Investigation in blood-brain barrier integrity and susceptibility to immune cell penetration in a mouse model of Dravet syndrome
Published 2025-03-01“…The elevated number of blood neutrophils did not apparently originate their infiltration into the hippocampus of DS mice as an immunofluorescence analysis indicated, and the same happened in B- and T-cells. …”
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369
Linking obesity-associated genotype to child language development: the role of early-life neurology-related proteomics and brain myelinationResearch in context
Published 2025-03-01“…Additionally, the expression of the EPH-Ephrin signalling pathway in the hippocampus might contribute to language development. …”
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