-
201
Methamphetamine Use: A Narrative Review of Adverse Effects and Related Toxicities
Published 2022-09-01“…Methamphetamine-induced neurotoxicity in serotonergic systems is more diffuse, involving the striatum, hippocampus, septum, amygdala, and hypothalamus leading to mood changes, psychosis, and memory impairment. …”
Get full text
Article -
202
Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus
Published 2016-01-01“…In the dentate gyrus of the hippocampus, enriched environments evoke especially profound neural changes, including increases in the number of neurons and the number of dendritic spines. …”
Get full text
Article -
203
Sequence of episodic memory-related behavioral and brain-imaging abnormalities in type 2 diabetes
Published 2025-02-01“…Imaging biomarkers included structural and functional MRI features of the entorhinal cortex-hippocampus and hippocampus-anterior cingulate cortex pathways. …”
Get full text
Article -
204
Shi-Zhen-An-Shen Decoction, a Herbal Medicine That Reverses Cuprizone-Induced Demyelination and Behavioral Deficits in Mice Independent of the Neuregulin-1 Pathway
Published 2021-01-01“…Hyperlocomotor activity was accompanied by significant reductions in MBP expression in the corpus callosum, hippocampus, and cerebral cortex. However, both QTP and SZASD significantly reversed the schizophrenia-like behaviors and demyelination in CPZ-fed mice. …”
Get full text
Article -
205
Synaptic Plasticity and Excitation-Inhibition Balance in the Dentate Gyrus: Insights from In Vivo Recordings in Neuroligin-1, Neuroligin-2, and Collybistin Knockouts
Published 2018-01-01“…In this minireview, we discuss recent studies unraveling molecular mechanisms of excitatory/inhibitory synaptic transmission, long-term synaptic plasticity, and dentate granule cell excitability in the hippocampus of live animals. We focus on the role of three major postsynaptic proteins localized at excitatory (neuroligin-1) and inhibitory synapses (neuroligin-2 and collybistin). …”
Get full text
Article -
206
Lingguizhugan decoction enhances autophagy of Alzheimer’s disease via regulating the mTOR/ p70s6K pathway in vivo and in vitro
Published 2025-01-01“…Morris water maze (MWM) was used to evaluate the mice’s learning and memory ability. Mice’s hippocampus tissue sections were stained immunohistochemically to observe hippocampal Aβ deposition. …”
Get full text
Article -
207
Experimental Study on the Central Mechanism of Penehyclidine Hydrochloride against Relapse Behavior in Morphine-Dependent Rats
Published 2022-01-01“…Each group was randomly divided into 5 subgroups (n=10): 4 h after administration, 7 h after administration, 13 h after administration, 25 h after administration (K48, LP48, MP48, and HP48), and 37 h after administration, and then, Morris water maze experiment and immunohistochemical detection of the rat brain hippocampus were carried out. Results. 4 and 7 hours after administration, compared with group 1, the TchE activity increased and Ach level decreased in groups 2, 3, and 4 and the difference was significant (P<0.05), so the principle of penehyclidine hydrochloride against morphine-dependent rats is that penehyclidine hydrochloride causes cognitive impairment in the brain of mice, thereby achieving antimorphine effects.…”
Get full text
Article -
208
The edge of chaos is that where consciousness manifests itself through intermittent dynamics
Published 2024-01-01“…Dudkin on slices of the CA1 field of the hippocampus.…”
Get full text
Article -
209
Early life stress and altered social behaviors: A perspective across species
Published 2025-02-01“…Animal models have been integral in identifying both the short- and long-term consequences of stress exposure and suggest that whether it is disruption to parental care or social isolation, chronic exposure to early life stress increases corticosterone, changes the expression of neurotransmitters and neuromodulators, and facilitates structural alterations to the hypothalamus, hippocampus, and amygdala, influencing how these brain regions communicate with other reward-related substrates. …”
Get full text
Article -
210
Robust Diffeomorphic Mapping via Geodesically Controlled Active Shapes
Published 2013-01-01“…In this work, we seek to use template surfaces to generate segmentations of the hippocampus with three data attachment terms: surface matching, landmark matching, and inside-outside modeling from grayscale T1 MR imaging data. …”
Get full text
Article -
211
Electroconvulsive shock and transcranial magnetic stimulation do not alter the survival or spine density of adult-born striatal neurons.
Published 2025-01-01“…Adult neurogenesis has most often been studied in the hippocampus and subventricular zone-olfactory bulb, where newborn neurons contribute to a variety of behaviors. …”
Get full text
Article -
212
Therapeutic Potential of 5-HT2C Receptor Ligands
Published 2010-01-01“…Anatomically, they are present in various brain regions, including cortical areas, hippocampus, ventral midbrain, striatum, nucleus accumbens, hypothalamus, and amygdala. …”
Get full text
Article -
213
Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition
Published 2016-01-01“…Thus, we hypothesize that PARP-1 may be altered in postmortem hippocampus of individuals with AD compared to age-matched controls without neurologic disease. …”
Get full text
Article -
214
Noradrenergic Modulation of Cognition in Health and Disease
Published 2017-01-01“…Two areas of dense noradrenergic innervation, the prefrontal cortex and the hippocampus, are particularly important with regard to these functions. …”
Get full text
Article -
215
Immune Challenge Alters Reactivity of Hippocampal Noradrenergic System in Prenatally Stressed Aged Mice
Published 2019-01-01“…A PS-induced proinflammatory status of the organism may result in an impairment of both hippocampal synaptic plasticity and hippocampus-dependent memory formation in adults. We addressed here the question of how PS-induced alterations in the immune response in young and old mice may contribute to changes in hippocampal function in aging. …”
Get full text
Article -
216
Role of Hypothalamus in Acupuncture’s Effects
Published 2025-01-01“…Acupuncture, a traditional oriental medicine, can affect brain regions, such as the hypothalamus, anterior cingulate, posterior cingulate, and hippocampus, and produces specific therapeutic effects, such as pain relief, suppression of hypertension, and alleviation of drug addiction. …”
Get full text
Article -
217
Mimicking Neural Stem Cell Niche by Biocompatible Substrates
Published 2016-01-01“…During development, the primary NSCs are distributed along the ventricular zone of the neural tube, while, in adults, NSCs are mainly restricted to the subependymal layer of the subventricular zone of the lateral ventricles and the subgranular zone of the dentate gyrus in the hippocampus. The circumscribed areas where the NSCs are located contain the secreted proteins and extracellular matrix components that conform their niche. …”
Get full text
Article -
218
Effects of Metabolic Dysfunction–Associated Steatohepatitis in Alertness, Associative Learning, and Astrocyte Density
Published 2025-01-01“…Also, we explored the astrocyte density in the prefrontal cortex and hippocampus. Results Our results showed that, whereas the MASH group did not display an impaired associative learning, a lower exploration rate was found in this group. …”
Get full text
Article -
219
Lactoferrin alleviates the adverse effects of early-life inflammation on depression in adults by regulating the activation of microglia
Published 2025-02-01“…The results show that lactation lactoferrin deficiency increases depression-like behavior in adult mice, and the mechanism is associated with heightened neuronal damage, abnormal microglial activation, and decreased BDNF in the hippocampus. In contrast, recombinant human lactoferrin promotes neuronal proliferation by upregulating ERK 1 and 2 phosphorylation and attenuates LPS-induced neuronal injury and microglial activation by inhibiting the activation of Toll-like receptor 4—nuclear factor-kappa B pathway in vitro. …”
Get full text
Article -
220
Adult Hippocampal Neurogenesis in Parkinson’s Disease: Impact on Neuronal Survival and Plasticity
Published 2014-01-01“…The generation of newborn neurons in the adult hippocampus and in the subventricular zone/olfactory bulb system is affected by many different regulators and possibly involved in memory processing, depression, and olfaction, symptoms which commonly occur in PD. …”
Get full text
Article