Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice by Jiayin Zheng, Yue Wang, Song Han, Yanlin Luo, Xiuli Sun, Ning Zhu, Li Zhao, Junfa Li

“…Meanwhile, the expression of cPKCβII, nPKCε, and cPKCγ did not change in the hippocampus, cortex, and striatum at 2 and 8 weeks after STZ injection. …”
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Effect of Electroacupuncture at Shenting and Baihui Acupoints on Ability of Learning and Memory and Expression of Autophagy Related Genes and Proteins in Cerebral Ischemia-reperfus... by Lingli GAO, Xiaodong FENG

“…Objective:To explore the mechanism of cognitive impairment treated by electroacupuncture (EA), and the expression of autophagy related genes and proteins in hippocampus of cerebral ischemia-reperfusion rats after EA at the shengting (DU24) and baihui (DU20) acupoints treament would be observed.Methods:A total of 48 SD male rats of clean grade were randomly divided into the EA group (<italic>n</italic>=18), the model group (<italic>n</italic>=18) and the sham operation group (<italic>n</italic>=12). …”
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Effects of Exercise Preconditioning Mediating Oxidative Stress to Regulate PI3K/Akt and Nrf2/HO-1 Pathways to Alleviate Cognitive and Learning Disorders in Rats by KONG Haijun, LI Xinlong, WANG Fenghua, CHEN Xiaoan

“…The changes of Nissl corpuscles in CA1 region of hippocampus were observed by Nissl staining. mRNA expression levels of PI3K, Nox1, Duox2 and Akt were detected by RT-PCR. …”
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Circular RNA circ-Olfm1 induces progression of Alzheimer’s disease by regulating FOXO3a by YANG Hongyan, LIAO Qirong, HOU Mingliang

“…These differentially expressed genes are mainly involved in signal transduction, learning and memory and other functions. circ-Olfm1 was identified as the most significantly differentially expressed circRNA, which is highly expressed in the neurons and up-regulated in the cerebral cortex and hippocampus of the AD mice. Knockout of circ-Olfm1 reduced the number of Aβ plaques in the cerebral cortex and hippocampus of AD mice (P<0.01). …”
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Ripples Make Waves: Binding Structured Activity and Plasticity in Hippocampal Networks by Josef H. L. P. Sadowski, Matthew W. Jones, Jack R. Mellor

“…In this paper, we explore the ways in which SWRs and other network events can bridge the gap between spatiomnemonic processing at cellular/synaptic and network levels in the hippocampus.…”
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Enhanced detection of mild cognitive impairment in Alzheimer’s disease: a hybrid model integrating dual biomarkers and advanced machine learning by John Sahaya Rani Alex, R. Roshini, G. Maneesha, Jeetashree Aparajeeta, B. Priyadarshini, Chih-Yang Lin, Chi-Wen Lung

“…A 3D-CNN architecture is employed to segment the hippocampus from the structural brain 3D-MR images and quantify the hippocampus volume. …”
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Prediction models for cognitive impairment in middle-aged patients with cerebral small vessel disease by Wei Zheng, Xiaoyan Qin, Ronghua Mu, Peng Yang, Bingqin Huang, Bingqin Huang, Zhixuan Song, Xiqi Zhu, Xiqi Zhu

“…An Unet-based deep learning neural network model was developed to automate the segmentation of the hippocampus. Features were extracted for each subject, and the least absolute shrinkage and selection operator (LASSO) method was used to select radiomic features. …”
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Suspension of Mitotic Activity in Dentate Gyrus of the Hibernating Ground Squirrel by Victor I. Popov, Igor V. Kraev, Dmitri A. Ignat'ev, Michael G. Stewart

“…Neurogenesis occurs in the adult mammalian hippocampus, a region of the brain important for learning and memory. …”
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Electroacupuncture Stimulation Suppresses Postoperative Inflammatory Response and Hippocampal Neuronal Injury by Xiang-feng Wang, Qin Lin, Guan-hui Wang, Gen-ming Zhan, Wei Liu, Zhi-wei Lin

“…The peripheral inflammation response and the neuron impairment and inflammation response in the hippocampus was significantly reduced by the electroacupuncture stimulation. …”
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Therapeutic potential of rutin in premenstrual depression: evidence from in vivo and in vitro studies by Xiangjun Wang, Xiaowen Xia, Xianliang Song, Yi Zhou, Mingyu Ma, Yashuang Ren, Xitai Chen, Zenghui Xia, Yinghui Guo, Chunhong Song

“…HE staining and Golgi staining were performed to observe the neuronal damage in rat hippocampus. UHPLC-MS/MS targeted metabolomics was performed to detect the changes of neurotransmitter content in rat hippocampus. …”
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Effect of Electroacupuncture at Baihui Acupoint on Magnetic Resonance Spectroscopy and Spatial Learning and Memory Ability in APP/PS1 Transgenic Mice by Yingzheng ZHANG, Peiyuan ZHUO, Ruhui LIN, Lidian CHEN

“…Morris water maze was used to test spatial learning and memory ability in the fourth week. NAA, Glu of the hippocampus were detected by¹H-MRS.Results:Compared with the model group, the level of NAA and Glu were significantly increased (<italic>P</italic>&lt;0.05). …”
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Clocking In Time to Gate Memory Processes: The Circadian Clock Is Part of the Ins and Outs of Memory by Oliver Rawashdeh, Rex Parsons, Erik Maronde

“…These memory-essential signaling components cycle rhythmically in the hippocampus across the day and night and are clearly molded by an intricate interplay between the circadian system and memory. …”
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RNA helicase MOV10 suppresses fear memory and dendritic arborization and regulates microtubule dynamics in hippocampal neurons by Temirlan Shilikbay, Aatiqa Nawaz, Megan Doon, Stephanie Ceman

“…Numa1 mRNA is a MOV10 CLIP target and is among the genes significantly decreased in Mov10 Deletion hippocampus. Restoration of NUMA1 expression and knockdown of HAUS rescued phenotypes of the Mov10 Deletion hippocampal neurons. …”
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Thalamic spindles and Up states coordinate cortical and hippocampal co-ripples in humans. by Charles W Dickey, Ilya A Verzhbinsky, Sophie Kajfez, Burke Q Rosen, Christopher E Gonzalez, Patrick Y Chauvel, Sydney S Cash, Sandipan Pati, Eric Halgren

“…The widespread co-occurrences of ripples ("co-ripples") may integrate information across the neocortex and hippocampus to facilitate consolidation. While the thalamus synchronizes spindles and Up states in the cortex for memory, it is not known whether it may also organize co-ripples. …”
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A human single-neuron dataset for object recognition by Runnan Cao, Peter Brunner, Nicholas J. Brandmeir, Jon T. Willie, Shuo Wang

“…The human amygdala and hippocampus play a key role in object recognition, contributing to both the encoding and retrieval of visual information. …”
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Acute Toxicity and Neuroprotective Effect of “RJ6601”, a Newly Formulated Instant Soup, in Geriatric Rats by Rujikarn Chaisanam, Jintanaporn Wattanathorn

“…Given its antioxidant effects and central nervous system benefits, we hypothesized that RJ6601 should improve neurodegeneration in the hippocampus, a region critical for cognition and the maintenance of quality of life (QoL). …”
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Astroglial Plasticity Is Implicated in Hippocampal Remodelling in Adult Rats Exposed to Antenatal Dexamethasone by Vishvesh H. Shende, Simon McArthur, Glenda E. Gillies, Jolanta Opacka-Juffry

“…The relative volume of the dorsal hippocampus (% of total brain volume) showed a moderate, by 8%, but significant reduction in dexamethasone-treated versus control animals. …”
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Therapeutic Metaphors Enhance Memory Systems in Mental Health Contexts by Fei Yu, Zhijie Zhang, Wencai Zhang

“…Insightfulness and activities of the hippocampus, caudate, and cerebellum could predict memory performance. …”
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Oleuropein Improves Cognitive Dysfunction and Neuroinflammation in Diabetic Rats through the PI3K/Akt/mTOR Pathway by Jianru Shang, Shan Che, Mingjie Zhu

“…It also could improve oxidative stress and inflammatory response and activate the PI3K/Akt/mTOR signaling pathway in hippocampus tissues. Conclusion. Oleuropein ameliorates cognitive dysfunction and neuroinflammation in diabetic rats by regulating the PI3K/Akt/mTOR signaling pathway.…”
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Sugammadex-Enhanced Neuronal Apoptosis following Neonatal Sevoflurane Exposure in Mice by Maiko Satomoto, Zhongliang Sun, Yushi U. Adachi, Koshi Makita

“…Exposure to 2% sevoflurane for 6 h resulted in BBB ultrastructural abnormalities in the hippocampus of neonatal mice.…”
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