Unveiling the signal valve specifically tuning the TGF-β1 suppression of osteogenesis: mediation through a SMAD1-SMAD2 complex by Ying-Wen Wang, Ching-Wei Luo

“…Ingenuity Pathway Analysis, and analysis of transcriptomic datasets from human BM-MSCs in combination with hierarchical clustering and STRING assay were used to decipher the interplaying co-repressors. …”
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Assessment of multidecadal precipitation seasonality in the panama canal watershed by István Gábor Hatvani, Nayara Azevedo de Castro Souza, Russell S. Harmon, Jorge A. Espinosa, Zoltán Kern

“…The focus interval of 2000–2017 offered the most complete spatiotemporal coverage of the long-term seasonal variability explored by hierarchical cluster analysis. Since the ENSO22 El Niño Southern Oscillation is a key driver of hydroclimate variability in central Panama, differences in the rainfall patterns during the six most prominent El Niño and La Niña events, having respective ENSO indices of > 1.80 and < ˗1.63, were compared to quasi-neutral conditions for the assigned hydroclimatological domains. …”
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Obtaining strength-ductility combination in a laser additive manufactured (FeCoNi)86Al7Ti7 high-entropy alloy at cryogenic temperature by Kaiqiang Xie, Yacheng Fang, Pan Ma, Hong Yang, Shiguang Wan, Konda Gokuldoss Prashanth, Piter Gargarella, Yongkun Mu, Gang Wang, Yandong Jia

“…The PBF HEA exhibits a hierarchical microstructure with columnar grains, Ti-enriched cellular substructures entangled with high-density dislocations, and L21 nanoprecipitates, contributing to an excellent strength-ductility combination at room temperature. …”
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Factors influencing trust among colleagues in hospital settings: a systematic review by Andreea Isabela Varga, Ivan Spehar, Frode Veggeland, Helge Skirbekk

“…Studies were excluded if they only explored trust between healthcare professionals on different hierarchical levels. Theoretical studies, systematic reviews, conceptually unclear papers and anecdotal case studies were also excluded. …”
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Global leukemia burden and trends: a comprehensive analysis of temporal and spatial variations from 1990—2021 using GBD (Global Burden of Disease) data by Pengyu Huang, Jie Zhang

“…We employed descriptive, trend, cluster, and forecasting analyses using age-standardized rates (ASRs) and the Estimated Annual Percentage Change (EAPC) to quantify changes over time. Hierarchical clustering and forecasting models, including ARIMA and Exponential Smoothing (ES), were utilized to predict future trends. …”
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Clinical evaluation of long-read sequencing-based episignature detection in developmental disorders by Mathilde Geysens, Benjamin Huremagic, Erika Souche, Jeroen Breckpot, Koenraad Devriendt, Hilde Peeters, Griet Van Buggenhout, Hilde Van Esch, Kris Van Den Bogaert, Joris Robert Vermeesch

“…Following genomic variant and methylome calling, hierarchical clustering and dimensional reduction were used to determine the compatibility with microarray-based episignatures. …”
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The temporal scale of energy maximization explains allometric variations in movement decisions of large herbivores by Daniel Fortin, Christopher F. Brooke, Hervé Fritz, Jan A. Venter

“…Radio‐collared individuals of the three species spent 95% of their time >850 m from one another. Hierarchical movement analysis revealed that red hartebeest and zebra selected grasslands within which they selected patches maximizing their daily energy gains. …”
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Functional connectome gradient of prefrontal cortex as biomarkers of high risk for internet gaming disorder by Xinwen Wen, Lirong Yue, Zhe Du, Jiahao Zhao, Mengjiao Ge, Cunfeng Yuan, Hongmei Wang, Qinghua He, Kai Yuan

“…We used functional connectome gradient (FCG) to capture the macroscopic hierarchical organization of human brain. Canonical correlation analysis was employed to identify components mapping relationships between FCG and behavioral scores. …”
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Factors associated with hypercholesterolemia in older adults: A cross‐sectional investigation by Maria Clara Alves deOliveira, Júlia Perfeito Andrade, Ana Carolina Souza Porto, Gizelly Maria Torres Martins, Nurielly Monteiro Campos, Paulo daFonseca Valença Neto, Claudio Bispo De Almeida, Saulo Sacramento Meira, Beatriz Cardoso Roriz, Débora Jesus daSilva, Victor Giovannino Accetta, Cezar Augusto Casotti, Lucas dosSantos

“…Gross models were initially developed, followed by a hierarchical multiple explanatory model (Level 1: socioeconomic variables; Level 2: behavioral aspects; Level 3: health conditions). …”
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Morpho-meristic variations of the native and Vietnam-originated climbing perch (Anabas testudineus), collected from hatchery sources in Bangladesh by Md. Arif Shahariar, Md. Mahamudul Hassan, Swagata Aditya, Tanjina Saulin, Atika Khondokar, Mohammad Shafiqul Alam

“…Principal component analysis indicated that native and Vietnam-originated climbing perch can be distinguished from one another using the two distinctive morphological parameters-total length (TL) and PVFL. Hierarchical cluster analysis showed high divergence between the native and exotic populations in Bangladesh and successfully grouped the populations based on their strains. …”
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A Multiport Electric Energy Routing Scheme Applied to Battery Energy Storage System by Guanglin Sha, Qing Duan, Wanxing Sheng, Aiqiang Pan, Zhe Liu, Chunyan Ma, Caihong Zhao, Jiaxun Teng, Lumin Fu, Yi Zheng

“…The working principle of current fed isolated bidirectional DC-DC converter (CF-IBDC) and cascaded H-bridge (CHB) is analyzed, and the decoupling control strategy is designed. In this paper, a hierarchical control strategy is designed for the repurposed battery energy storage (RBES) grid-connected system based on CPET, which consists of three layers: energy layer, power layer, and state of charge (SOC) layer. …”
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Analysis of health expenditures in China from 2000 to 2019 compared with the world and upper-middle-income countries by Xindian Zeng, Xindian Zeng, Lijie Chen, Lu Chen

“…The government should continue to optimize the financing structure of THE, increase GHE, encourage social capital investment, decrease the proportion of OOPHE, diversify financing and reimbursement policies to promote hierarchical medical system, promote health management for an aging population, and formulate health expenditure plans for public health emergencies.…”
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Characterization and typology of goat production systems in the Southern Highlands of Peru by Emmanuel Alexander Sessarego, Fritz Carlos Trillo, David José Godoy, Walter Palomino-Guerrera, Juancarlos Alejandro Cruz

“…Factor analysis of mixed data and hierarchical classification analysis were conducted to identify typologies of goat production systems using R version 4.4.2. …”
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UNet-Att: a self-supervised denoising and recovery model for two-photon microscopic image by Yuer Lu, Yongfa Ying, Chen Lin, Yan Wang, Jun Jin, Xiaoming Jiang, Jianwei Shuai, Xiang Li, Jinjin Zhong

“…Specifically, this approach consists of a sophisticated downsampling module for extracting hierarchical features at varied scales, and an innovative attention module that strategically emphasizes salient features during the integration process. …”
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Does attachment and prenatal depression affect maternal health-promoting lifestyle during pregnancy? A cross-sectional study by Rufidah Maulina, Su-Chen Kuo, Chieh-Yu Liu, Yu Ying Lu, Siti Khuzaiyah, Rafael A. Caparros-Gonzalez

“…However, factors such as age, living arrangement, gestational age, a planned pregnancy, previous miscarriages, pre-pregnancy diseases, pre-pregnancy complications, and a private health insurance showed no significant associations. Hierarchical multiple linear regression indicated that maternal-fetal attachment (p < 0.05) and maternal depression (p < 0.001) were the only predictors of pregnant women's health-promoting lifestyles (R2 = 0.373, ΔR = 0.251). …”
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Anaplastic Thyroid Carcinoma: A ceRNA Analysis Pointed to a Crosstalk between SOX2, TP53, and microRNA Biogenesis by Walter Arancio, Valeria Carina, Giuseppe Pizzolanti, Laura Tomasello, Maria Pitrone, Concetta Baiamonte, Marco Calogero Amato, Carla Giordano

“…Previous studies suggested that the stem cell factor SOX2 has a preeminent hierarchical role in determining the characteristics of stem cells in SW1736 ATC cell line. …”
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Modification of Platelet Count on the Association between Homocysteine and Blood Pressure: A Moderation Analysis in Chinese Hypertensive Patients by Jianan Zhang, Jing Li, Shi Chen, Linglin Gao, Xiaoluan Yan, Mingzhi Zhang, Jia Yu, Fenchun Wang, Hao Peng

“…Leveraging a community-based cross-sectional survey in 30,369 Chinese hypertensive patients (mean age 62 years, 52% female), we examined the moderation of platelet count on the association between serum homocysteine and BP by constructing hierarchical multiple regression models, adjusting for conventional risk factors. …”
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Potential toxic elements in surface water of Mokosh Beel, Gazipur, Bangladesh: Ecological and human health risk assessment for recreational users by Md. Shahriar Mahmud, M. Safiur Rahman, S.A. Dina, M. Rifat Nasher, Tasrina R. Choudhury, Bilkis A. Begum, Abdus Samad

“…Principal component analysis (PCA) and hierarchical cluster analysis (HCA) linked the majority of PTEs to industrial sources, particularly from tannery, leather, and paint industries. …”
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Polycaprolactone for Hard Tissue Regeneration: Scaffold Design and In Vivo Implications by Fernanda Ramírez-Ruiz, Israel Núñez-Tapia, María Cristina Piña-Barba, Marco Antonio Alvarez-Pérez, Vincenzo Guarino, Janeth Serrano-Bello

“…Different techniques can be used to manufacture 3D scaffolds for bone tissue regeneration based on optimizing reproducible scaffolds with a controlled hierarchical porous structure like the extracellular matrix of bone. …”
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Implementasi Latent Dirichlet Allocation (LDA) untuk Klasterisasi Cerita Berbahasa Bali by Ngurah Agus Sanjaya ER

“…The research stages include story digitization, tokenization, case-folding, stemming, topic search with LDA, document representation and agglomerative hierarchical clustering. Performance evaluation was carried out using 100 Balinese folklores data obtained from online sites and the Bali Provincial Cultural Office to calculate the accuracy of the clustering results. …”
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