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481
The Effect of the Platelet Administration for the Patients with Liver Dysfunction after Liver Resection: Preliminary Clinical Trial
Published 2021-01-01“…Six patients with hepatocellular carcinoma and liver cirrhosis have received the partial hepatectomy in the institution. …”
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482
Oral Floor and Gingival Metastasis of Cholangiocarcinoma: A Case Report and Review of the Literature
Published 2014-01-01“…The most common primary sites that metastasize to the oral cavity are lung, kidney, breast, and hepatocellular carcinoma. We present a rare case of a 77-year-old Caucasian female with metastasis from a cholangiocarcinoma to the oral floor contiguous with lingual gingival mucosa. …”
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483
Unveiling the mystery of hepatic epithelioid angiomyolipoma: A unique case report with literature review
Published 2025-01-01“…Initial imaging misdiagnosed the mass as hepatocellular carcinoma. Following multidisciplinary treatment discussions and subsequent tumor resection, histopathology and immunohistochemistry confirmed hepatic epithelioid angiomyolipoma. …”
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484
Towards an HCV vaccine: an overview of the immunization strategies for eliciting an effective B-cell response
Published 2025-12-01“…Introduction Fifty-eight million people worldwide are chronically infected with hepatitis C virus (HCV) and are at risk of developing cirrhosis and hepatocellular carcinoma (HCC). Direct-acting antivirals are highly effective; however, they are burdened by high costs and the unchanged risk of HCC and reinfection, making prophylactic countermeasures an urgent medical need. …”
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485
The Laboratory Diagnosis of Hepatitis B Virus
Published 2005-01-01“…Without intervention, approximately 15% to 40% of chronically infected individuals will eventually develop cirrhosis, end-stage liver disease or hepatocellular carcinoma, or require liver transplantation. …”
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486
The Role of Interventional Endoscopic Ultrasound in Liver Diseases: What Have We Learnt?
Published 2021-01-01“…Chronic liver disease (CLD) is still a major problem, where the disease progression will lead to liver cirrhosis (LC) or hepatocellular carcinoma (HCC). Portal hypertension (PH) management and loco-regional therapy for HCC have become the cornerstones in advanced liver disease management. …”
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487
The Role of Sulfatides in Liver Health and Disease
Published 2025-01-01“…Previous studies have shown elevated levels of sulfatides in hepatocellular carcinoma (HCC), where sulfatides could act as adhesive molecules that contribute to cancer metastasis. …”
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488
Why and How to Treat Chronic Hepatitis C
Published 2000-01-01“…Chronic hepatitis C (CHC) is a major health problem worldwide, with approximately 200 million affected individuals and a significant rate of progression to end-stage cirrhosis and hepatocellular carcinoma (HCC). If hepatitis C virus (HCV) infection is left untreated in the population, then the number of liver-related deaths will soon double and the need for liver transplantation may increase to five times that seen today. …”
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489
Two Patients with Extremely Elevated Tumor Markers: Where Is the Malignancy?
Published 2011-01-01“…Extensive imaging showed no signs of hepatocellular carcinoma or other cancer, and treatment with Prednisone led to rapid normalization of both liver enzymes and aFP. …”
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490
A Case of Hepatic Malignant Solitary Fibrous Tumor: A Case Report and Review of the Literature
Published 2023-01-01“…Contrast-enhanced CT abdomen showed a large left hepatic lobe mass with early enhancement and delayed venous washout, concerning for hepatocellular carcinoma. Fine needle aspiration showed numerous spindle cells with malignant nuclear features, suggestive of malignant spindle cell neoplasm. …”
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491
Associations between Extracellular Matrix Protein 1 Gene Polymorphism and Progression of Liver Disease
Published 2022-01-01“…Of the disease group, 104 cases had chronic hepatitis B (CHB), 266 had LC, and 286 had hepatocellular carcinoma (HCC). Subjects were frequency-matched according to age and gender. …”
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492
Secretion of One Adipokine Nampt/Visfatin Suppresses the Inflammatory Stress-Induced NF-κB Activity and Affects Nampt-Dependent Cell Viability in Huh-7 Cells
Published 2015-01-01“…However, its function in chronic inflammation and carcinogenesis in hepatocellular carcinoma (HCC) has not been well-defined. Here we use Huh-7 hepatoma cells as a model to determine how Nampt/visfatin affects cellular survival under oxidative stress. …”
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493
Design, Synthesis, and Biological Evaluation of Triazolyl- and Triazinyl-Quinazolinediones as Potential Antitumor Agents
Published 2019-01-01“…The antitumor activity of the synthesized compounds was evaluated against two human cell lines: human colon carcinoma HCT116 and human hepatocellular carcinoma HEP-G2. Some of the tested compounds showed significant potency compared to the reference drug staurosporin.…”
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494
Retrospective evaluation of a novel ultrasound-based imaging analysis software for predicting radiofrequency ablation areas.
Published 2025-01-01“…<h4>Objective</h4>This study aimed to introduce and evaluate a novel software-based system, BioTrace, designed for real-time monitoring of thermal ablation tissue damage during image-guided radiofrequency ablation for hepatocellular carcinoma (HCC).<h4>Methods</h4>BioTrace utilizes a proprietary algorithm to analyze the temporo-spatial behavior of thermal gas bubble activity during ablation, as seen in conventional B-mode ultrasound imaging. …”
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495
The dynamics of a delay model of hepatitis B virus infection with logistic hepatocyte growth
Published 2009-02-01“…Chronic HBV affects 350 million people and can lead to death through cirrhosis-inducedliver failure or hepatocellular carcinoma. We analyze the dynamics of a model consideringlogistic hepatocyte growth and a standard incidence function governing viral infection.This model also considers an explicit time delay in virus production. …”
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496
Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells
Published 2016-12-01“…The flavonoid rutin was investigated for its anti-carcinogen and protective effects as well as modulatory action on CYPs and phase II enzymes in human hepatocellular carcinoma cells. Rutin inhibited proliferation of HEPG2 cells in a dose-dependent manner with the IC50 value of 52.7 μmol L-1 and invasion of HEPG2 cells (21.6 %, p = 0.0018) and colony formation of those invaded cells (57.4 %, p < 0.0001). …”
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497
Unfavorable Tumor Responses to Immunotherapy in the Liver: Lessons Learned from Clinical and Preclinical Studies
Published 2023-04-01“…Results: In patients with advanced hepatocellular carcinoma or esophageal cancer, non-small cell lung cancer, or melanoma with liver metastases, the efficacy of ICI-based therapy was generally lower in the liver than in other organs. …”
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498
The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control
Published 2012-01-01“…Moreover, its disregulation has been associated with the promotion of tumor cell growth of a variety of tumors, including hepatocellular carcinoma. Whereas the strict specificity of action of ERK1 and ERK2 is still debated, the MAPKs may have specific biological functions under certain contexts and according to the differentiation status of the cells, notably hepatocytes. …”
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499
Effect of Intervention of Vaccination and Treatment on the Transmission Dynamics of HBV Disease: A Mathematical Model Analysis
Published 2022-01-01“…Since people do not give attention, it will develop into cirrhosis and hepatocellular carcinoma that leads to liver transplantation and death. …”
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500
Exploring the association between air pollution and the incidence of liver cancers
Published 2025-01-01“…Liver cancer, namely hepatocellular carcinoma (HCC), is a major global health concern deeply influenced by environmental factors. …”
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