The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy by Sherif El-Saadany, Dina H Ziada, Hanan El Bassat, Wael Farrag, Hesham El-Serogy, Manal Eid, Manal Abdallah, Medhat Ghazy, Hoda A Salem

“…BACKGROUND: The underlying mechanisms of hepatitis C virus (HCV) resistance to treatment are unknown. …”
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Increased Eligibility for Treatment of Chronic Hepatitis C Infection with Shortened Duration of Therapy: Implications for Access to Care and Elimination Strategies in Canada by Sergio M Borgia, Adenike Rowaiye

“…BACKGROUND: All oral, highly effective direct-acting antiviral combinations, such as sofosbuvir-ledipasvir, have recently been licensed in Canada but cost as much as $67,000 for a 12-week course of therapy, representing a major economic barrier to predominately single-payer health care systems such as that found in Ontario. In hepatitis C virus (HCV) genotype 1 noncirrhotic patients with a baseline viral load of <6×106 IU/mL, treatment with sofosbuvir-ledipasvir can be shortened to eight weeks without compromising ≥95% efficacy. …”
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Localized Scleroderma Associated with Chronic Hepatitis C by Felipe Ladeira de Oliveira, Luisa Kelmer Côrtes de Barros Silveira, Maria Lourdes Candela Rambaldi, Fabio Cuiabano Barbosa

“…Hepatitis C virus has been associated with various skin conditions, such as porphyria cutanea tarda and lichen planus, as an example. …”
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High Human Immunodeficiency Virus (HIV) Viral Load and Coinfection with Viral Hepatitis Are Associated with Liver Enzyme Abnormalities among HIV Seropositive Patients on Antiretrov... by Shabani Iddi, Caroline A. Minja, Vitus Silago, Asteria Benjamin, Jastine Mpesha, Shimba Henerico, Benson R. Kidenya, Stephen E. Mshana, Mariam M. Mirambo

“…Hepatitis B virus (HBV) and Hepatitis C virus (HCV) detection and liver enzymes assays (alanine transaminase (ALAT) and aspartate transaminase (ASAT)) were assessed following the standard procedures. …”
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CIHR Canadian HIV Trials Network Coinfection and Concurrent Diseases Core: Canadian Guidelines for Management and Treatment of HIV/Hepatitis C Coinfection in Adults by Mark Hull, Marina Klein, Stephen Shafran, Alice Tseng, Pierre Giguère, Pierre Côté, Marc Poliquin, Curtis Cooper, on behalf of The CIHR Canadian HIV Trials Network HIV/Hepatitis C Management and Treatment Guidelines Working Group

“…BACKGROUND: Hepatitis C virus (HCV) coinfection occurs in 20% to 30% of Canadians living with HIV, and is responsible for a heavy burden of morbidity and mortality. …”
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Recent Advances in Antiviral Therapy for Chronic Hepatitis C by Akihiro Tamori, Masaru Enomoto, Norifumi Kawada

“…Hepatitis C virus (HCV) infection is a major worldwide health problem. …”
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PPAR Could Contribute to the Pathogenesis of Hepatocellular Carcinoma by Osamu Kimura, Yasuteru Kondo, Tooru Shimosegawa

“…Viral hepatitis with hepatitis C virus or hepatitis B virus and chronic liver disease such as alcoholic or nonalcoholic steatohepatitis are critical factors in the development of hepatocellular carcinoma (HCC). …”
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Hepatocyte Turnover in Chronic HCV-Induced Liver Injury and Cirrhosis by Nikolaos P. Karidis, Ioanna Delladetsima, Stamatios Theocharis

“…Chronic hepatitis C virus (HCV) infection may eventually lead to progressive liver fibrosis and cirrhosis through a complex, multistep process involving hepatocyte death and regeneration. …”
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Oxidative stress in viral hepatitis by Huseyin Erdal, Hacer Ozlem Kalayci

“…Viral hepatitis, primarily caused by hepatitis B virus (HBV) and hepatitis C virus (HCV), is a leading cause of chronic liver disease worldwide. …”
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Retreatment with Pegylated Interferon Alpha-2a and Ribavirin in Patients with Chronic Hepatitis C Who Have Relapsed or Not Responded to a First Course of Pegylated Interferon-Based... by Eric M Yoshida, Morris Sherman, Vincent G Bain, Curtis L Cooper, Marc Deschênes, Paul J Marotta, Samuel S Lee, Mel Krajden, Helga Witt-Sullivan, Robert J Bailey, Christopher Usaty, Kevork Peltekian, the Canadian Pegasys Study Group

“…BACKGROUND: Pegylated interferon (pegIFN) and ribavirin combination therapy remains the first-line treatment for chronic hepatitis C virus (HCV) infection. In contrast to the wealth of studies in treatment-naive patients, the effectiveness of retreatment in patients who have previously failed pegIFN-based therapy is largely unreported.…”
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Treatment-Resistant Hepatitis C Viral Infection: A Case Report and Literature Review by Victoria Green, Marina Roytman

“…Hepatitis C virus (HCV) is an ongoing global public health threat affecting millions worldwide. …”
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Cognitive Impairments in Viral Hepatitis Patients: Causes, Manifestations, and Impact on Quality of Life by Tatyana Vasiliyevna Polukchi

“…Viral hepatitis, primarily caused by hepatitis B virus and hepatitis C virus, is widely recognized for its impact on liver function, but emerging evidence suggests it also affects cognitive function. …”
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Hepatitis C Transmission after Prostate Biopsy by Karim Ferhi, Morgan Rouprêt, Pierre Mozer, Guillaume Ploussard, Alain Haertig, Alexandre de La Taille

“…In this study, we report the case of a patient who contracted the hepatitis C virus after transrectal prostate biopsy as part of an individual screening for prostate cancer.…”
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Liver Transplantation and Hepatitis C by Nobuhisa Akamatsu, Yasuhiko Sugawara

“…Hepatitis-C-virus- (HCV-) related end-stage cirrhosis is the primary indication for liver transplantation in many countries. …”
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Motion – The Available Treatments for Hepatitis C Are Cost Effective: Arguments against the Motion by W Ray Kim

“…However, the natural history of hepatitis C virus (HCV) infection in the general population is not fully understood. …”
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Liver Cirrhosis: Evaluation, Nutritional Status, and Prognosis by Hiroki Nishikawa, Yukio Osaki

“…The liver is the major organ for the metabolism of three major nutrients: protein, fat, and carbohydrate. Chronic hepatitis C virus infection is the major cause of chronic liver disease. …”
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Subcutaneous Sarcoidosis during Pegylated Interferon Alfa and Ribavirin Treatment for Chronic Hepatitis C by R. Rodríguez-Lojo, M. Almagro, J. M. Barja, F. Piñeyro, L. Pérez-Varela, J. Del Pozo, M. T. Yebra-Pimentel, E. Fonseca

“…Interferon is used to treat hepatitis C virus infection and its cutaneous side effects are well known. …”
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HCV and Lymphoproliferation by Anna Linda Zignego, Carlo Giannini, Laura Gragnani

“…Hepatitis C virus (HCV) infection is a serious public health problem because of its worldwide diffusion and sequelae. …”
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Elastography in Hepatology by Ludovico Abenavoli, Christophe Corpechot, Raoul Poupon

“…Currently, there are only a few studies that have evaluated TE effectiveness in chronic liver diseases, mostly in patients infected with the hepatitis C virus. Further studies are needed in patients with chronic liver disease, to assess the effectiveness of the fibrosis treatment.…”
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Safety and efficacy of telaprevir in treatment of a chronic hepatitis C in patients of the Russian population included in early access program study by D. T. Abrurakhmanov, V. G. Morozov, I. G. Nikitin, P. O. Bogomolov, N. I. Geyvandova, Ye. N. Bessonova, I. G. Bakulin, V. A. Isakov, K. V. Zhdanov, M. V. Mayevskaya, Ye. A. Nurmukhametova, E. Z. Burnevich, Ye. V. Chesnokov, V. D. Pasechnikov, A. Hill, I. Lonjon-Domanec, S. N. Kizhlo

“…In 153 patients with severe liver fibrosis caused by hepatitis C virus (genotype 1), on background of triple AVT with telaprevir high level of immediate virologic response and low level of the preterm treatment discontinuation was marked.…”
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