The Second Canadian Symposium on Hepatitis C Virus: A Call to Action by Jason Grebely, Marc Bilodeau, Jordan J Feld, Julie Bruneau, Benedikt Fischer, Jennifer F Raven, Eve Roberts, Norma Choucha, Rob P Myers, Selena M Sagan, Joyce A Wilson, Frank Bialystok, D Lorne Tyrrell, Michael Houghton, Mel Krajden, on behalf of the National CIHR Research Training Program in Hepatitis C

“…In Canada, hepatitis C virus (HCV) infection results in considerable morbidity, mortality and health-related costs. …”
Get full text

The Role of Type III Interferons in Hepatitis C Virus Infection and Therapy by Janina Bruening, Bettina Weigel, Gisa Gerold

“…Among the three classes of IFNs, type III IFNs, also called IFN lambdas (IFNLs), are an essential component of the innate immune response to hepatitis C virus (HCV). In particular, human polymorphisms in IFNL gene loci correlate with hepatitis C disease progression and with treatment response. …”
Get full text

Asian Perspective on Hepatitis B Virus and Hepatitis C Virus Elimination by Apichat Kaewdech, Phunchai Charatcharoenwitthaya, Teerha Piratvisuth

“…Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections remain significant public health challenges in Asia, affecting millions and contributing to substantial morbidity and mortality. …”
Get full text

Cytoskeletal Vimentin Directs Cell‐Cell Transmission of Hepatitis C Virus by Yifan Xing, Zeyu Wen, Jie Mei, Xinyi Huang, Shuangshuang Zhao, Jin Zhong, Yaming Jiu

Subjects: Get full text

The Relationship between Inflammatory Marker Levels and Hepatitis C Virus Severity by Qitian He, Quan He, Xue Qin, Shan Li, Taijie Li, Li Xie, Yan Deng, Yu He, Yongbin Chen, Zhifu Wei

“…We aim to investigate the relationship between RDW and PLR and the severity of hepatitis C virus- (HCV-) related liver disease. Methods. …”
Get full text

Detection of Antibody to Envelope (E2) Antigen of Hepatitis C Virus by RK Chaudhary, E Burres

“…One hundred and four clinical specimens from provincial public health laboratories were tested for antibody to hepatitis C virus (HCV) envelope protein (anti-E2). To evaluate the effect of hypervariability of E2 region on anti-E2 assay, 49 recombinant immunoblot assay (RIBA) 3.0 positive samples were genotyped. …”
Get full text

Complementary and Alternative Medicine Use by Patients Chronically Infected with Hepatitis C Virus by Colin P White, Gerilynn Hirsch, Sunil Patel, Fatin Adams, Kevork M Peltekian

“…The extent of use of CAM in chronic hepatitis C virus (HCV) infected patients was determined, and the demographic and clinical data between users and nonusers of CAM was compared.…”
Get full text

Peroxisome Proliferator-Activated Receptors and Hepatitis C Virus-Induced Insulin Resistance by Francesco Negro

“…Insulin resistance and type 2 diabetes are associated with hepatitis C virus infection. A wealth of clinical and experimental data suggests that the virus is directly interfering with the insulin signalling in hepatocytes. …”
Get full text

Global Dynamics and Applications of an Epidemiological Model for Hepatitis C Virus Transmission in China by Mingwang Shen, Yanni Xiao, Weike Zhou, Zhen Li

Get full text

Hepatitis C Virus Infection and Hospital-Related Outcomes: A Systematic Review by Michelle Ng, Patrizia Maria Carrieri, Lindila Awendila, Maria Eugenia Socías, Rod Knight, Lianping Ti

Get full text

Capacity Enhancement of Hepatitis C Virus Treatment through Integrated, Community-Based Care by Warren D Hill, Gail Butt, Maria Alvarez, Mel Krajden

“…BACKGROUND: An estimated 250,000 Canadians are infected with the hepatitis C virus (HCV). The present study describes a cohort of individuals with HCV referred to community-based, integrated prevention and care projects developed in British Columbia. …”
Get full text

Cost-effectiveness of Triple Therapy with Telaprevir for Chronic Hepatitis C Virus Patients in Germany by Jona T. Stahmeyer, Svenja Schauer, Siegbert Rossol, Hans Heinrich Wedemeyer, Daniel Wirth, Florence Bianic, Christian Krauth

Get full text

Hepatitis C Virus Evasion from RIG-I-Dependent Hepatic Innate Immunity by Helene Minyi Liu, Michael Gale

“…Exposure to hepatitis C virus (HCV) usually results in persistent infection that often develops into chronic liver disease. …”
Get full text

Factors Associated with Spontaneous Clearance of Hepatitis C Virus among Illicit Drug Users by Jason Grebely, Jesse D Raffa, Calvin Lai, Mel Krajden, Brian Conway, Mark W Tyndall

“…BACKGROUND: Spontaneous clearance of hepatitis C virus (HCV) occurs in approximately 25% of individuals.…”
Get full text

Autoimmunity and Extrahepatic Manifestations in Treatment-Naïve Children with Chronic Hepatitis C Virus Infection by Giuseppe Indolfi, Elisa Bartolini, Biagio Olivito, Chiara Azzari, Massimo Resti

“…Hepatitis C virus (HCV) infection has been associated with autoimmunity and extrahepatic manifestations in adults. …”
Get full text

Living with Hepatitis C Virus: A Systematic Review and Narrative Synthesis of Qualitative Literature by Laura E. Dowsett, Stephanie Coward, Diane L. Lorenzetti, Gail MacKean, Fiona Clement

“…The aim of this systematic review was to understand the experiences of living with Hepatitis C Virus (HCV). Methods. Five databases were searched from inception until January 19, 2015. …”
Get full text

Cryoglobulinaemia in Egyptian Patients with Extrahepatic Cutaneous Manifestations of Chronic Hepatitis C Virus Infection by Doaa Salah Hegab, Mohammed Abd El Rahman Sweilam

“…Mixed cryoglobulinaemia (MC) shows a striking association with hepatitis C virus (HCV) infection, and it is sometimes asymptomatic. …”
Get full text

Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department by Kelsey Ragan, Anjali Pandya, Tristan Holotnak, Katrina Koger, Neil Collins, Mark G. Swain

“…Approximately 0.7% of the Canadian population is infected with hepatitis C virus (HCV), and many individuals are unaware of their infection. …”
Get full text

Successful Integration of Hepatitis C Virus Point-of-Care Tests into the Denver Metro Health Clinic by A. Jewett, A. A. Al-Tayyib, L. Ginnett, B. D. Smith

“…The Centers for Disease Control and Prevention (CDC) recommends testing and linkage to care for persons most likely infected with hepatitis C virus (HCV), including persons with human immunodeficiency virus. …”
Get full text

Sofosbuvir-Based Therapies for Patients with Hepatitis C Virus Infection: Real-World Experience in China by Chengguang Hu, Guosheng Yuan, Junwei Liu, Huaping Huang, Yanyu Ren, Yinping Li, Xuefu Chen, Wei Li, Tao Wu, Hong Deng, Yanzhong Peng, Yong-Yuan Zhang, Yuanping Zhou

“…There is scarcity of data in literature regarding the treatment response to sofosbuvir- (SOF-) based therapies in Chinese patients with chronic Hepatitis C Virus (HCV) infection. The aim of this study was to evaluate the efficacy and safety of SOF-based regimens for chronic hepatitis C (CHC) patients without cirrhosis in a real-world setting in mainland China. …”
Get full text