Epidemiological trends in gastrointestinal cancers and risk factors across U.S. states from 2000 to 2021: a systematic analysis for the global burden of disease study 2021 by Jiahao Jiang, Zhiqin Xie, Qingbin Wang, Bingkun Wang, Rong Huang, Weikai Xu, Changzhen Shang, Yajin Chen

“…For esophageal, stomach, and colorectal cancers, mortality rates linked to diet and smoking decreased, whereas alcohol-related mortality increased in several states, especially West Virginia. Hepatitis C remains the leading cause of liver cancer, with intravenous drug use as the primary risk factor. …”
Get full text

Assessment of the Impact of Floods to the Local Community in Nyarusiza Sub-County Kisoro District. by Murengezi, Innocent

“…The findings on the second objective revealed that the spread of Communicable Diseases is the main effect of waterborne diseases like cholera, typhoid fever, hepatitis, and leptospirosis in flood-affected areas. …”
Get full text

Right Gastroepiploic Artery as an Alternative for Arterial Reconstruction in Living Donor Liver Transplantation by Klaus Steinbrück, Reinaldo Fernandes, Marcelo Enne, Rafael Vasconcelos, Giuliano Bento, Gustavo Stoduto, Thomas Auel, Lúcio Filgueiras Pacheco-Moreira

“…A 62-year-old woman, with cirrhosis due to hepatitis B associated with hepatocellular carcinoma, was submitted to living donor liver transplantation. …”
Get full text

MORIX: Machine learning-aided framework for lethality detection and MORtality inference with eXplainable artificial intelligence in MAFLD subjects by Domenico Lofù, Paolo Sorino, Tommaso Colafiglio, Caterina Bonfiglio, Rossella Donghia, Gianluigi Giannelli, Angela Lombardi, Tommaso Di Noia, Eugenio Di Sciascio, Fedelucio Narducci

“…Metabolic dysfunction-associated fatty liver disease (MAFLD) introduces new diagnostic criteria for fatty liver disease that are independent of alcohol consumption and viral hepatitis infection. Therefore, investigating how biochemical and anthropometric factors influence mortality in MAFLD subjects is of significant interest. …”
Get full text

Identification and characterization of multiple novel viruses in fecal samples of cormorants by Li Ji, Li Ji, Ran Zhao, Yifei Pei, Yijie Sun, Xiaoyi Sun, Likai Ji, Xiaochun Wang, Yuwei Liu, Quan Shen, Shixing Yang, Yan Wang, Wen Zhang

“…Compared with other avian hepatitis E virus strains, CormhepaE has multiple variable sites, which are distributed in motifs of the methyltransferase, helicase, and RdRp domains, separately. …”
Get full text

Exploring the potential of some natural indoles as antiviral agents: quantum chemical analysis, inverse molecular docking, and affinity calculations by Amany Belal, Aly Abdou, Samar F. Miski, Mohamed A. M. Ali, Heba I. Ghamry, Ahmad J. Obaidullah, Ahmad J. Obaidullah, Mohamed Y. Zaky, Ahmed H. E. Hassan, Ahmed H. E. Hassan, Eun Joo Roh, Eun Joo Roh, Ahmed A. Al-Karmalawy, Ahmed A. Al-Karmalawy, Mona H. Ibrahim

“…Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infections represent critical global health challenges due to the high morbidity and mortality associated with co-infections. …”
Get full text

The role of immunotherapy in the treatment of lip squamous cell carcinoma: A series of six cases and a review of the current literature by Ido Amir, Nir Tsur, Itamar Averbuch, Gideon Bachar, Noga Kurman

“…Adverse effects included severe myositis (n = 1), arthralgia (n = 1), psoriasis (n = 1), esophagitis (n = 1), mild hepatitis (n = 1) and pruritus (n = 2). Management included corticosteroids (topical or systemic) and/or 2nd generation antihistamines and treatment cessation as indicated. …”
Get full text

Could Infectious Agents Play a Role in the Onset of Age-related Macular Degeneration? A Scoping Review by Petra P. Larsen, MD, PhD, Virginie Dinet, PhD, Cécile Delcourt, PhD, Catherine Helmer, MD, PhD, Morgane Linard, MD, PhD

“…Only Chlamydia pneumoniae, Cytomegalovirus, and hepatitis B virus received more attention with 17, 6, and 4 studies, respectively. …”
Get full text

Pooled prevalence and associated factors of traditional uvulectom among children in Africa: A systematic review and meta-analysis. by Solomon Demis Kebede, Kindu Agmas, Demewoz Kefale, Amare Kassaw, Tigabu Munye Aytenew

“…The reuse of unsafe tools such as blades, needles, or thread loops exacerbates the spread of infectious diseases like HIV and hepatitis B. Despite its clinical significance, the pooled prevalence and associated factors of TCU have not been adequately examined through systematic reviews or meta-analyses.…”
Get full text

Increased CCR7loPD-1hiCXCR5+CD4+ T Cells in Peripheral Blood Mononuclear Cells Are Correlated with Immune Activation in Patients with Chronic HBV Infection by Ya-Xin Huang, Qi-Yi Zhao, Li-Li Wu, Dong-Ying Xie, Zhi-Liang Gao, Hong Deng

“…T follicular helper cells (Tfh cells) affect essential immune pathogenesis in chronic hepatitis B virus (HBV) infection. The CCR7loPD-1hi Tfh subset has a partial Tfh effector phenotype and is associated with active Tfh differentiation, whereas the CCR7hiPD-1lo Tfh subset is a resting phenotype. …”
Get full text

Association of gross domestic product with equitable access to childhood vaccines in 195 countries: a systematic review and meta-analysis by Kwabena Obeng Duedu, Yakhya Dieye, Andreas Ateke Njoh, Jerome Nyhalah Dinga, Jones Soladoye Akinbobola, Funmilayo Ibitayo Deborah Afolayan, Tesfaye Kassa, David Dazhia Lazarus, Gezahegne Mamo Kassa, Nefefe Tshifhiwa, Mustapha Oumouna

“…Global vaccination coverage for tuberculosis, diphtheria/tetanus/pertussis, hepatitis B, Haemophilus influenzae type b, measles, polio, meningitis and HPV had a significantly higher coverage than COVID-19. …”
Get full text

Gallstone Ileus following Endoscopic Stone Extraction by Yoshiya Yamauchi, Noritaka Wakui, Yasutsugu Asai, Nobuhiro Dan, Yuki Takeda, Nobuo Ueki, Takahumi Otsuka, Nobuyuki Oba, Shuta Nisinakagawa, Tatsuya Kojima

“…An 85-year-old woman was an outpatient treated at Tokyo Rosai Hospital for cirrhosis caused by hepatitis B. She had previously been diagnosed as having common bile duct stones, for which she underwent endoscopic retrograde cholangiopancreatography (ERCP). …”
Get full text

Brazilian Gold Miners Working Irregularly in French Guiana: Health Status and Risk Determinants by Amanda Figueira da Silva, Vivian da Cruz Franco, Maylis Douine, Hermano Gomes Albuquerque, Louise Hureau, Alice Sanna, Pamela Mosquera Atehortua, Rafael dos Santos Pereira, Simone da Silva Santos, Paola Barbosa Marchesini, Gustavo Bretas, Margarete do Socorro Mendonça Gomes, Yann Lambert, Martha Cecília Suárez-Mutis

“…Other diseases mentioned were skin diseases, bat bites, hepatitis, and HIV infection. This vulnerable population is constantly subjected to heavy routines and exposed to different diseases and infections that can spread across borders. …”
Get full text

Clinical Presentation, Risk Factors, and Treatment Modalities of Hepatocellular Carcinoma: A Single Tertiary Care Center Experience by Abdulrahman A. Aljumah, Hadi Kuriry, Mohammed AlZunaitan, Mohammed Al Ghobain, Mohamed Al Muaikeel, Ashwaq Al Olayan, Fahad Azzumeea, Bader Almutairi, Abduljaleel AlAlwan, Hamdan AlGhamdi

“…Males had higher tumor size and incidence of portal vein thrombosis. Viral hepatitis was a risk factor in 75.7%. The most common BCLC stages were B (34.5%) and A (33.6%), and the most common radiological presentation was a single nodule of less than 5 cm. …”
Get full text

A Case of Solitary Necrotic Nodule Treated with Laparoscopic Hepatectomy: Spontaneous Regression of Hepatocellular Carcinoma? by Hirokazu Tomishige, Zenichi Morise, Yoshikazu Mizoguchi, Norihiko Kawabe, Hidetoshi Nagata, Hisanori Ohshima, Jin Kawase, Satoshi Arakawa, Rie Yoshida, Masashi Isetani

“…Also, the findings of chronic hepatitis were observed in the background liver.…”
Get full text

DNA Damage Sensor γ-H2AX Is Increased in Preneoplastic Lesions of Hepatocellular Carcinoma by Yasunobu Matsuda, Toshifumi Wakai, Masayuki Kubota, Mami Osawa, Masaaki Takamura, Satoshi Yamagiwa, Yutaka Aoyagi, Ayumi Sanpei, Shun Fujimaki

“…The level of γ-H2AX was measured by immunohistochemistry in fifty-eight HCC, 18 chronic hepatitis, 22 liver cirrhosis, and 19 dysplastic nodules. …”
Get full text

Time to antiretroviral therapy initiation in HIV-positive patients with opportunistic infections/AIDS-defining illness in Southern Thailand: a prospective cohort study by Chanadda Wuttikul, Nattasiri Thanawuth, Malee Rojpibulsatit, Sutthiporn Pattharachayakul

“…On the other hand, the factors associated with a longer time to ART initiation were tuberculosis co-infection (aHR = 0.52; 95% CI: 0.36-0.75), HIV diagnosis after OIs/ADI (aHR = 0.42; 95% CI: 0.30-0.57), viral hepatitis B/C co-infection (aHR = 0.59; 95% CI: 0.39-0.89), seeking care in general hospital and community hospital (aHR = 0.67; 95% CI: 0.49-0.93, and aHR = 0.62; 95% CI: 0.44-0.86, respectively), having more than one hospital admission in the past six months (aHR = 0.60; 95% CI: 0.44-0.81), and history of missed appointments (aHR = 0.62; 95% CI: 0.42-0.91). …”
Get full text

Identification of climate-sensitive disease incidences in vietnam: A longitudinal retrospective analysis of infectious disease rates between 2014 and 2022 by Cuong Quoc Hoang, Quang Phuong Huynh Nguyen, Thao Phuong Huynh Nguyen, Hieu Trung Nguyen, Linh Thuy Hoang, Giang Huong Vu, Woong-Ki Kim, Hai Duc Nguyen

“…Result: The five infectious diseases with the highest average incidence rates per 100,000 people were diarrhea; hand, foot, and mouth disease (HFMD); dengue fever; viral hepatitis; and influenza. Positive associations with humidity were observed for dengue fever and HFMD. …”
Get full text

High CD163 Expression on Classical Monocytes Is Associated with Immune Control of HBV Infection in Noncirrhotic Patients by Anna Parfieniuk-Kowerda, Kamil Grubczak, Andrzej Eljaszewicz, Magdalena Świderska, Magdalena Maciaszek, Anatol Panasiuk, Jerzy Jaroszewicz, Robert Flisiak, Marcin Moniuszko

“…CD163 expression on classical monocytes was associated with status of immune control and thus significant in HBV infection as compared to active hepatitis. Plasma sCD163 concentration was increased in CHB patients and those with HBsAg/anti-HBs seroconversion vs. the control group. …”
Get full text

Drug-Drug Interactions Between HIV Antivirals and Concomitant Drugs in HIV Patients: What We Know and What We Need to Know by Emanuela De Bellis, Danilo Donnarumma, Adele Zarrella, Salvatore Maria Mazzeo, Annarita Pagano, Valentina Manzo, Ines Mazza, Francesco Sabbatino, Graziamaria Corbi, Pasquale Pagliano, Amelia Filippelli, Valeria Conti

“…Protease inhibitors, followed by nonnucleoside reverse transcriptase inhibitors and integrase inhibitors have been recognized as the main players in DDIs with antivirals used to control co-infection, such as Hepatitis C virus, or with drugs commonly used to treat HIV comorbidities, such as lipid-lowering agents, proton pump inhibitors and anticancer drugs. …”
Get full text