Cardamom extract alleviates tamoxifen-induced liver damage by suppressing inflammation and pyroptosis pathway by Wedad S. Sarawi, Hala A. Attia, Afraa Alzoubi, Nour Alanazi, Raeesa Mohammad, Rehab A. Ali

“…TAM exposure resulted in apparent degenerations in hepatic tissue with inflammatory cell infiltration and loss of architectures. …”
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Effects of dietary dihydroartemisinin on growth performance, meat quality, and antioxidant capacity in broiler chickens by Xiaoxiao Pu, Yuxuan Liang, Jiafang Lian, Miaoxuan Xu, Yalan Yong, Hao Zhang, Lili Zhang, Jingfei Zhang

“…Dihydroartemisinin quadratically increased the hepatic mRNA expression of Nrf2. Compared to the control group, dihydroartemisinin at 10 and 20 mg/kg quadratically induced the hepatic mRNA expression of HO-1. …”
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Noninvasive Assessment of Liver Fibrosis by Magnetic Resonance Elastography in Patients with Rheumatic Disease on Long-Term Methotrexate Treatment by Arindam Nandy Roy, Anjani Kumar Darapureddy, Yarram Ashok Kumar

“…Background: Long-term methotrexate (MTX) use is associated with hepatic fibrosis in patients with rheumatic diseases. …”
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Complement Receptors C5aR and C5L2 Are Associated with Metabolic Profile, Sex Hormones, and Liver Enzymes in Obese Women Pre- and Postbariatric Surgery by Reza Rezvani, Jessica Smith, Marc Lapointe, Picard Marceau, Andre Tchernof, Katherine Cianflone

“…C5L2-C5aR association with other mediators including estrogens may contribute to hepatic metabolic and inflammatory function.…”
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Pathological and Molecular Characterization of Grass Carp Co-Infected with Two <i>Aeromonas</i> Species by Wenyao Lv, Zhijie Zhou, Lingli Xie, Xinyue Wang, Yifei Zhou, Lang Gui, Xiaoyan Xu, Yubang Shen, Jiale Li, Junqiang Qiu

“…Quantitative analysis demonstrated significantly elevated bacterial loads in hepatic tissue at 3 days post-infection (dpi). Histopathological evaluation revealed severe hepatic lesions characterized by cellular necrosis, cytoplasmic vacuolization, and hemorrhagic manifestations. …”
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Pharmacological insights and therapeutic advances of mangiferin against various pathological conditions in liver diseases by Tanvir Zaman Shoyshob, Sumaya Akter, Muhammad Ramiz Uddin, Mithila Farjana, Akhi Moni, Wonhyo Seo, Md. Golzar Hossain, Md Jamal Uddin

“…Several studies have suggested that pretreatment with mangiferin decreases hepatic inflammation, oxidative stress, apoptosis, fibrosis, endoplasmic reticulum (ER) stress, and hepatic dysfunction and concomitantly ameliorates the morphological structures of the liver. …”
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Single-Cell RNA Sequencing Reveals Macrophage Dynamics During MASH in <i>Leptin</i>-Deficient Rats by Xiaoming Xin, Yaohua Ni, Jing Wang, Fenglin Wu, Meichen Liu, Lingjuan Wu, Jiaxing Dai, Chenglin Wu, Xiaolei Song, Wang Zhang, Guangrui Yang, Ruling Shen, Xianmin Zhu

“…In humans and mice, the cellular heterogeneity and diverse function of hepatic macrophages in MASH have been investigated by single cell RNA sequencing (scRNA-seq). …”
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A Rare Case of Spontaneous Cardiac Tamponade Induced by Concomitant Use of Rivaroxaban and Amiodarone by Oreoluwa Oladiran, Jared Segal, Ifeanyi Nwosu, Salik Nazir

“…Both rivaroxaban and amiodarone are substrates for the CYP3A4 hepatic pathway, and concomitant use can result in increased plasma rivaroxaban levels causing an increased propensity to bleeding. …”
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Preoperative predictive factors of cystobiliary fistulas in liver hydatid cysts: results of a monocentric study by Mohamed Salah Jarrar, Ines Karmani, Mehdi Chahed, Malek Barka, Mohamed Hedi Mraidha, Radhouane Toumi, Ameni Beizig, Khayri Dhouioui, Sabri Youssef

“…Introduction The evolution of hepatic hydatid cyst can be enameled with complications, mainly biliary fistula, which can be both symptomatic or occult. …”
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Nitrones: not only extraordinary spin traps, but also good nitric oxide sources in vivo by Croitoru Mircea Dumitru, Petkes Hermina Iulia, Fülöp Ibolya, Cotârlan Remus, Şerban Oana Elena, Dogaru Titica Maria, Gâz Florea Şerban Andrei, Tőkés Béla, Majdik Cornelia

“…At the same time, nitrones do not react with hepatic homogenates, proving that the release of nitric oxide takes place in the tissues and is not related to hepatic metabolism. …”
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Rofecoxib-Induced Hepatotoxicity: A Forgotten Complication of the Coxibs by Brian Yan, Yvette Leung, Stefan J Urbanski, Robert P Myers

“…Although the coxibs are generally well-tolerated, rofecoxib was recently withdrawn from the market due to concerns regarding cardiovascular safety. Rare cases of hepatic injury attributable to the coxibs have been reported. …”
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The Implications of Liver Biopsy Results in Patients with Myeloproliferative Neoplasms Being Treated with Ruxolitinib by Douglas Tremblay, Juan Putra, Alexander Vogel, Adam Winters, Ronald Hoffman, Thomas D. Schiano, Maria Isabel Fiel, John O. Mascarenhas

“…Ruxolitinib is increasingly being utilized for the treatment of myelofibrosis and polycythemia vera, but the potential for hepatic toxicity is poorly understood. We performed a retrospective review of hepatic damage occurring in patients with myeloproliferative neoplasms receiving ruxolitinib. …”
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Modulation of Innate Immunity by G-CSF and Inflammatory Response by LBPK95A Improves the Outcome of Sepsis in a Rat Model by Haoshu Fang, Chuanfeng Hua, Stefanie Weiss, Anding Liu, Wenhui Cheng, Ralf Claus, Jürgen Rödel, Olaf Dirsch, Uta Dahmen

“…G-CSF treatment increased the white blood cell counts, hepatic neutrophil infiltration, and bacterial clearance in the liver, lung, and blood. …”
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Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats by Elin Strand, Vegard Lysne, Mari Lausund Grinna, Pavol Bohov, Asbjørn Svardal, Ottar Nygård, Rolf K. Berge, Bodil Bjørndal

“…Thus, the aim was to compare the metabolic response in hepatic, adipose, and cardiac tissues after treatment with specific PPAR agonists. …”
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Effects of Delta-Like Noncanonical Notch Ligand 1 Expression of Human Fetal Liver Hepatoblasts on Hematopoietic Progenitors by Jörg C. Gerlach, Robert L. Thompson, Bruno Gridelli, Eva Schmelzer

“…Although the hepatic and hematopoietic progenitors of the liver are well characterized, the interactions between these two lineages remain mostly elusive. …”
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Docosahexaenoic and Eicosapentaenoic Acid Supplementation Could Attenuate Negative Effects of Maternal Metabolic Syndrome on Liver Lipid Metabolism and Liver Betacellulin Expressio... by Tomislav Mašek, Petra Roškarić, Sunčica Sertić, Kristina Starčević

“…<b>Background/Objectives</b>: This study investigated the effects of maternal metabolic syndrome during pregnancy on hepatic fatty acid metabolism and betacellulin expression in rat offspring. …”
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Model of Liver Fibrosis Induction by Thioacetamide in Rats for Regenerative Therapy Studies by Nathaly Enciso, José Amiel, Fredy Fabián-Domínguez, Jhon Pando, Nancy Rojas, Carlos Cisneros-Huamaní, Ernesto Nava, Javier Enciso

“…Hepatic fibrosis is caused by chronic injury due to toxic, infectious, or metabolic causes, and it may progress to cirrhosis and hepatocellular carcinoma. …”
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Terminalia catappa Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene by Franklyn Nonso Iheagwam, Gaber El-Saber Batiha, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu

“…A significant (p<0.05) upregulation of hepatic TNF-α and IL-6 expression and downregulation (p<0.05) of Nrf-2 expression were observed during diabetes onset. …”
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Surgical Strategy in Patients with Complete Transposition of Internal Organs in Cancer of the Biliopancreatoduodenal Zone by R. V. Ischenko, Yu. V. Ivanov, A. V. Smirnov, V. N. Antipov

“…In addition to the situs vicserum inversus, this patient revealed a special variant of vascular anatomy, namely: separate separation of the left and right hepatic arteries from the ventral trunk. A 70-year-old man, in addition to complete transposition of internal organs, had a combination of cancer of the terminal part of the common bile duct and heterotaxy syndrome in the form of polysplenia, aplasia of the hepatic segment of the inferior vena cava, agenesis of the dorsal pancreatic rudiment (“short” pancreas), intrapancreatic course of the right hepatic artery extending from the superior mesenteric arteries, rotational abnormalities of intestinal development. …”
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Long-Term Suitability of Left Gastric Artery Inflow for Arterial Perfusion of Living Donor Right Lobe Grafts by Judyta A. Lipinska, Johnny Wang, Joseph N. Carey, Aaron A. Ahearn, Yuri S. Genyk

“…At grafting, the risk for later thrombosis is high if a dissected hepatic artery is used for standard reconstruction. …”
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