An Unusual Presentation of Glandular Fever by Dominic Worku, Li Hui Chang, Ian Blyth

“…Common complications include but are not limited to hepatitis, splenomegaly, encephalitis, and haemophagocytic lymphohistiocytosis (HLH) with evidence that Caucasian males and smokers are more likely to suffer severe disease. …”
Get full text

Timosin alpha-1 immunomodulating properties by M. V. Mayevskaya

“…Efficacy of Timosin alpha-1 was demonstrated in the treatment of one of the most difficult groups of patients with persistent hepatitis C virus infection – non-responders at combined treatment by interferon and ribavirin. …”
Get full text

Foxp3 Expression in Liver Correlates with the Degree but Not the Cause of Inflammation by Matthaios Speletas, Nikoletta Argentou, Georgios Germanidis, Themistoclis Vasiliadis, Konstantinos Mantzoukis, Kalliopi Patsiaoura, Pavlos Nikolaidis, Vaios Karanikas, Konstantinos Ritis, Anastasios E. Germenis

“…Patients with chronic viral hepatitis display increased expression of Foxp3 in liver, suggesting that Tregs expansion contributes to persistent infection. …”
Get full text

Hepatocyte Turnover in Chronic HCV-Induced Liver Injury and Cirrhosis by Nikolaos P. Karidis, Ioanna Delladetsima, Stamatios Theocharis

“…Chronic hepatitis C virus (HCV) infection may eventually lead to progressive liver fibrosis and cirrhosis through a complex, multistep process involving hepatocyte death and regeneration. …”
Get full text

The Great Impostor: Transaminitis Masking the Coinfection of Syphilis and Human Immunodeficiency Virus by Sunit Tolia, Hassan Kassem, Ana Capatina-Rata

“…Conclusion. Syphilitic hepatitis is a recognized entity in the medical literature. …”
Get full text

Sorafenib-Induced Liver Failure: A Case Report and Review of the Literature by Anneleen Van Hootegem, Chris Verslype, Werner Van Steenbergen

“…In this paper, a patient with HCC with lung metastases developed high fever and a severe hepatitis that rapidly evolved into liver coma and death, two weeks after the initiation of Sorafenib. …”
Get full text

Drug Treatment of Patients with Liver Cirrhosis in a Tertiary Hospital in Northern Ghana: Does It Comply with Recommended Guidelines? by Baba Sulemana Mohammed, Matthew Aidoo

“…Common etiologies for liver cirrhosis were chronic hepatitis B 80 (52.6%) and chronic hepatitis C 30 (19.7%); about 12.5% of etiologies were unknown. …”
Get full text

Histomorphologic liver abnormalities in a group of alcoholic patients by Libán Álvarez Cáceres, Marcos Félix Osorio Pagola, Merlyn Arce Núñez.

“…<strong><br />Conclusion</strong>: there were a high proportion of patients with impaired liver aminotransferases and severe histological diagnoses, especially those of chronic hepatitis and liver cirrhosis.…”
Get full text

Allograft tolerance after adult living donor liver transplantation: a case-control study by Mohamed S. Habl, Moataz Maher Emara, Reham A. Zayed, Ahmed M. Sultan, Ahmed Elsabagh, Ahmed Marwan Elsaid, Ehab E. Abdel-khalek, Mohamed M. El-Saadany, Mohamed Abdel Wahab, Ahmed Shehta

“…Group 1 had a lower incidence of acute cellular rejection (ACR), recurrent viral hepatitis, and biliary complications. Logistic regression identified preoperative MELD, indication for LDLT, ACR, recurrent viral hepatitis, and biliary complications as significant predictors for allograft tolerance after LDLT. …”
Get full text

Etiologies and Outcomes of Acute Liver Failure in a Spanish Community by Emilio Fábrega, Miguel Ángel Mieses, Alvaro Terán, Irene Moraleja, Fernando Casafont, Javier Crespo, Fernando Pons-Romero

“…Previous retrospective study (1992 to 2000) performed in Spain showed that drug toxicity, viral hepatitis, and indeterminate etiology were the most prevalent causes of acute liver failure (ALF). …”
Get full text

Incidence of Severe Hepatotoxicity Related to Antiretroviral Therapy in HIV/HCV Coinfected Patients by Emily L. Heil, Mary L. Townsend, Kenneth Shipp, Amy Clarke, Melissa D. Johnson

“…Hepatotoxicity is a concern in HIV/hepatitis C virus (HCV) coinfected patients due to their underlying liver disease. …”
Get full text

Clinical Relevance of HLA Gene Variants in HBV Infection by Li Wang, Zhi-Qiang Zou, Kai Wang

“…Host gene variants may influence the natural history of hepatitis B virus (HBV) infection. The human leukocyte antigen (HLA) system, the major histocompatibility complex (MHC) in humans, is one of the most important host factors that are correlated with the clinical course of HBV infection. …”
Get full text

FLAIR Hyperintense Vessel Sign of Both MCAs with Severe Heart Failure by Donghee Kim, Seung-Yul Lee, Kwon-Duk Seo

“…In this patient, underlying chronic cerebral hypoperfusion and additionally decreased systemic perfusion seemed to provoke ischemic hepatitis and contribute to the development of FHVs.…”
Get full text

Entecavir-Associated Thrombocytopenia: A Case Report and Review of the Pathophysiology, Diagnosis, and Treatment of a Rare but Reversible Cause of Thrombocytopenia by Binoy Yohannan, Dai Chu N. Luu, Mark Feldman

“…She had undergone screening for hepatitis B virus (HBV) prior to starting rituximab and was found to have hepatitis B core serum antibody (IgG anti-HBc). …”
Get full text

Principles of effective out-patient diagnostics of diffuse liver diseases by Komova A. G., M. V. Mayevskaya, V. T. Ivashkin

“…Prevalence of diffuse liver diseases in the studied sample (n=4768) was following: non-alcoholic fatty liver disease —7,4% (n=352), alcohol-induced liver disease — 6,9% (n=329), hepatitis C — 6,7% (n=322), hepatitis B — 1,9% (n=91), drug-induced liver disease — 0,82% (n=39), cholestatic liver diseases — 0,69 % (n=33), autoimmune hepatitis — 0,78% (n=37), others — 5,4% (n=258). …”
Get full text

The role of the interleukin family in liver fibrosis by Zixin Zhang, Zixin Zhang, Jiahui Wang, Hui Li, Qun Niu, Qun Niu, Yujing Tao, Yujing Tao, Xin Zhao, Xin Zhao, Zijian Zeng, Zijian Zeng, Haijian Dong, Haijian Dong

“…Relevant studies have demonstrated that effective inhibition of hepatitis B virus (HBV) replication by nucleoside (acid) analogs or polyethylene glycol alpha-interferon can lead to recovery in some patients with hepatitis B liver fibrosis, However, some patients with liver fibrosis do not show improvement, even after achieving a complete serologic and virologic response. …”
Get full text

Current Treatment Regimens and Promising Molecular Therapies for Chronic Hepatobiliary Diseases by Marilena Durazzo, Arianna Ferro, Victor Manuel Navarro-Tableros, Andrea Gaido, Paolo Fornengo, Fiorella Altruda, Renato Romagnoli, Søren K. Moestrup, Pier Luigi Calvo, Sharmila Fagoonee

“…In this review, we highlight the major molecular changes occurring in patients affected by metabolic dysfunction-associated steatotic liver disease, viral hepatitis (Delta virus), and autoimmune chronic liver diseases (autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis). …”
Get full text

A Challenge for Diagnosing Acute Liver Injury with Concomitant/Sequential Exposure to Multiple Drugs: Can Causality Assessment Scales Be Utilized to Identify the Offending Drug? by Roxanne Lim, Hassan Choudry, Kim Conner, Wikrom Karnsakul

“…Drug-induced hepatotoxicity most commonly manifests as an acute hepatitis syndrome and remains the leading cause of drug-induced death/mortality and the primary reason for withdrawal of drugs from the pharmaceutical market. …”
Get full text

Porphyria Cutanea Tarda in a Patient with End-Stage Renal Disease: A Case of Successful Treatment with Deferoxamine and Ferric Carboxymaltose by Natacha Rodrigues, Fernando Caeiro, Alice Santana, Teresa Mendes, Leonor Lopes

“…The authors report a patient on haemodialysis, with hepatitis C infection, that is diagnosed with PCT. …”
Get full text

Acute and Fatal Isoniazid-Induced Hepatotoxicity: A Case Report and Review of the Literature by Wissam K. Kabbara, Aline T. Sarkis, Paola G. Saroufim

“…Laboratory results and imaging confirmed hepatitis. After ruling out all other possible causes, she was diagnosed with isoniazid-induced acute hepatitis (probable association by the Naranjo scale). …”
Get full text