Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy by Wenwen Wang, Liwei Wu, Jingjing Li, Jie Ji, Kan Chen, Qiang Yu, Sainan Li, Jiao Feng, Tong Liu, Jie Zhang, Jiaojiao Chen, Yuting Zhou, Yuqing Mao, Fan Wang, Weiqi Dai, Xiaoming Fan, Chuanyong Guo, Jianye Wu

“…Hepatic ischemia reperfusion (IR) injury (IRI) occurs during liver transplantation, hepatectomy, and hemorrhagic shock. …”
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Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice by Jiyeon Hwang, Sangbhin Lee, Junichi Okada, Li Liu, Jeffrey E. Pessin, Streamson C. Chua, Gary J. Schwartz, Young-Hwan Jo

“…Here, we investigate the impact of liver-projecting vagal sensory neurons on energy balance, hepatic steatosis, and anxiety-like behavior in mice under obesogenic conditions. …”
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Sex Differences in Spontaneous Degranulation Activity of Intrahepatic Natural Killer Cells during Chronic Hepatitis B: Association with Estradiol Levels by Zuzana Macek Jilkova, Thomas Decaens, Alice Marlu, Hélène Marche, Evelyne Jouvin-Marche, Patrice N. Marche

“…Major sex differences are observed in the prevalence, intensity, and severity of hepatitis B virus (HBV) infection. Here, we investigated degranulation activity of circulating and intrahepatic natural killer (NK) cells from HBV and HCV chronically infected patients before any treatment (n=125). …”
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Ergosterol alleviates hepatic steatosis and insulin resistance via promoting fatty acid β-oxidation by activating mitochondrial ACSL1 by Zu-Guo Zheng, Yi-Ping Zhang, Xiao-Yu Zhang, Meng-Yao Qin, Yin-Yue Xu, He Wu, Run-Qing Liu, Qiu-Yi Wu, Ming-Su Wang, Chong Zhang, Yue-Qin Zheng, Jian-Ye Dai, Ping Li, Hua Yang

“…Summary: Sterols target sterol-sensing domain (SSD) proteins to lower cholesterol and circulating and hepatic triglyceride levels, but the mechanism remains unclear. …”
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Early Changes in Hepatitis C Virus (HCV) RNA Levels Predict Response to Interferon Treatment in Non-Cirrhotic HCV Patients by Glen Fallows, Kelly Kaita, Gerald Minuk, Faye Penner, Gerry Smart, Magdy Dawood, Barry Rosser

“…The role of hepatitis C virus (HCV) RNA quantification in determining ideal interferon (IFN) treatment of noncirrhotic HCV liver disease is uncertain. …”
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Irisin Attenuates Hepatic Stellate Cell Activation and Liver Fibrosis in Bile Duct Ligation Mice Model and Improves Mitochondrial Dysfunction by Thuy Linh Lai, So Young Park, Giang Nguyen, Phuc Thi Minh Pham, Seon Mee Kang, Jeana Hong, Jae-Ho Lee, Seung-Soon Im, Dae-Hee Choi, Eun-Hee Cho

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Ultrastructural Characteristics of Rat Hepatic Oval Cells and Their Intercellular Contacts in the Model of Biliary Fibrosis: New Insights into Experimental Liver Fibrogenesis by Joanna Maria Lotowska, Maria Elzbieta Sobaniec-Lotowska, Dariusz Marek Lebensztejn, Urszula Daniluk, Piotr Sobaniec, Krzysztof Sendrowski, Jaroslaw Daniluk, Joanna Reszec, Wojciech Debek

“…Recently, it has been emphasized that hepatic progenitor/oval cells (HPCs) are significantly involved in liver fibrogenesis. …”
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Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene. by Min Zhang, Karim Mouzannar, Zhensheng Zhang, Yuji Teraoka, Jason Piotrowski, Yuji Ishida, Chise Tateno-Mukaidani, Takeshi Saito, Hiromi Abe-Chayama, Kazuaki Chayama, T Jake Liang

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The Outcome of Thoracentesis versus Chest Tube Placement for Hepatic Hydrothorax in Patients with Cirrhosis: A Nationwide Analysis of the National Inpatient Sample by Ali Ridha, Yasir Al-Abboodi, Matthew Fasullo

“…Of this, 1981 patients had a hepatic hydrothorax and ended up with either thoracentesis (1776) or chest tube (205). …”
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Novel digital droplet inverse PCR assay shows that natural clearance of hepatitis B infection is associated with fewer viral integrations by Dong Li, Vikki Ho, Chiao-Fang Teng, Hung-Wen Tsai, Yuanyuan Liu, Sarah Bae, Harout Ajoyan, Jochen M. Wettengel, Ulrike Protzer, Brian S. Gloss, Rebecca J. Rockett, Rafid Al Asady, Jane Li, Simon So, Jacob George, Mark W. Douglas, Thomas Tu

“…Hepatitis B virus (HBV) DNA integration into the host cell genome is reportedly a major cause of liver cancer, and a source of hepatitis B surface antigen (HBsAg). …”
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Cytomorphological Changes in the Hepate of the White Sea Coastal Cod (Gadus morhua maris-albi Derjugin, 1920) during Parasitic Invasions by Shakurova N.V., Kudryavtseva E.V.

Subjects: “…hepate of fish…”
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Development of a Recombinant Cell-Based Indirect Immunofluorescence Assay for the Determination of Autoantibodies against Soluble Liver Antigen in Autoimmune Hepatitis by Christiane Radzimski, Christian Probst, Bianca Teegen, Kristin Rentzsch, Inga Madeleine Blöcker, Cornelia Dähnrich, Wolfgang Schlumberger, Winfried Stöcker, Dimitrios P. Bogdanos, Lars Komorowski

“…Autoantibodies against soluble liver antigen (SLA) are specific markers for autoimmune hepatitis (AIH) type 1. In contrast to the determination of other AIH-associated autoantibodies by indirect immunofluorescence assay (IFA), detection of anti-SLA relied up to now on ELISA or immunoblot based on bacterially expressed recombinant protein. …”
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Increased Duodenal Iron Absorption through Upregulation of Ferroportin 1 due to the Decrement in Serum Hepcidin in Patients with Chronic Hepatitis C by Masanori Sato, Koji Miyanishi, Shingo Tanaka, Akira Sakurada, Hiroki Sakamoto, Yutaka Kawano, Kohichi Takada, Masayoshi Kobune, Junji Kato

“…Hepatic iron accumulation is generally increased in the chronic hepatitis C (CHC) liver; however, the precise mechanism of such accumulation remains unclear. …”
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Predictive Factors of Lamivudine Treatment Success in a Hepatitis B Virus-Infected Pediatric Cohort: A 10-Year Study by Yasmine Yousef, Kathie Béland, Emmanuel Mas, Pascal Lapierre, Dorothée Bouron Dal Soglio, Fernando Alvarez

“…BACKGROUND: Hepatitis B virus (HBV) infections are responsible for the development of chronic hepatitis in 400 million people worldwide. …”
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Pilot Study of Ofloxacin and Interferon-Alpha Combination Therapy for Chronic Hepatitis C without Sustained Response to Initial Interferon Therapy by Masafumi Komatsu, Tohru Ishii, Tsuyoshi Ono, Takao Hoshino, Tomoyuki Kuramitsu, Takashi Goto, Tomoo Fujii, Itaru Toyoshima, Mitsuro Chiba, Osamu Masamune

“…A controlled trial comparing combination therapy with ofloxacin (OFLX) and interferon (IFN) versus IFN monotherapy was conducted in patients with chronic hepatitis C who failed IFN therapy. …”
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Peer-assisted telemedicine hepatitis-C treatment for people who use drugs in rural communities: a mixed methods study by Kim Hoffman, Gillian Leichtling, Sarah Shin, Andrew Seaman, Tonhi Gailey, Hunter C. Spencer, P. Todd Korthuis

“…Abstract Background The increase in opioid use disorder among young, nonurban people has fueled sharp rises in hepatitis C virus (HCV) infections. Innovative treatment models are needed that circumvent healthcare system barriers for people who use drugs (PWUD), particularly in rural areas. …”
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Qizhu Rougan Granules suppress liver fibrosis by inhibiting the expression of the P2Y14 receptor on hepatic stellate cells by Yujing Tao, Yujing Tao, Qun Niu, Qun Niu, Yuanqian Yao, Yuanqian Yao, Kaixin Wang, Kaixin Wang, Haijian Dong, Haijian Dong, Xin Zhao, Xin Zhao, Zijian Zeng, Zijian Zeng, Hui Li

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Genotype 3 is linked to worse liver disease progression in hepatitis C patients even after SVR following DAA therapy by Xiping Ran, Xiping Ran, Yang Xu, Ying Wang, Cheng Zeng, Chen Gong, Ni Wang, Dachuan Cai, Dachuan Cai

Subjects: “…hepatitis C virus…”
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48-Week Outcome after Cessation of Nucleos(t)ide Analogue Treatment in Chronic Hepatitis B Patient and the Associated Factors with Relapse by Wen-xiong Xu, Qian Zhang, Xiang Zhu, Chao-shuang Lin, You-ming Chen, Hong Deng, Yong-yu Mei, Zhi-xin Zhao, Dong-ying Xie, Zhi-liang Gao, Chan Xie, Liang Peng

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Efficacy and Safety of a Novel Pegylated Interferon Alpha-2a in Egyptian Patients with Genotype 4 Chronic Hepatitis C by Alaa Awad Taha, Ahmad El-Ray, Maged El-Ghannam, Bahaa Mounir

“…BACKGROUND: Hepatitis C virus (HCV) genotype 4 is a common infection in Egypt and is the leading cause of liver disease.…”
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