Noninvasive diagnosis model for predicting significant liver inflammation in patients with chronic hepatitis B in the immune-tolerant phase by Shanshan Chen, Lu Huang, Yili Chu, Jiangshan Lian, Hui Shao, Tingting Wang, Xuehan Zou, Haijun Huang

Subjects: “…Chronic hepatitis B…”
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A New Metabolism-Related Index Correlates with the Degree of Liver Fibrosis in Hepatitis C Virus-Positive Patients by Hirayuki Enomoto, Nobuhiro Aizawa, Hideji Nakamura, Ryo Takata, Yoshiyuki Sakai, Yoshinori Iwata, Hironori Tanaka, Naoto Ikeda, Tomoko Aoki, Kunihiro Hasegawa, Kazunori Yoh, Kenji Hashimoto, Akio Ishii, Tomoyuki Takashima, Masaki Saito, Hiroyasu Imanishi, Hiroko Iijima, Shuhei Nishiguchi

“…The aim of this study was to investigate the relevance of an index obtained from three metabolic variables (glycated albumin: GA, glycated hemoglobin: HbA1c, and branched-chain amino acids to tyrosine ratio: BTR) to the degree of liver fibrosis in hepatitis C virus virus- (HCV-) positive patients. …”
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Seroprevalence and Risk Factors Associated with Hepatitis E Virus Infection in Three Species of Pet Birds in Northwest China by Wei Cong, Qing-Feng Meng, Xiao-Feng Shan, Wu-Wen Sun, Si-Yuan Qin, Xiao-Xuan Zhang, Si-Yang Huang, Ai-Dong Qian

“…Hepatitis E virus (HEV), the causative agent of hepatitis E, has been reported in a wide variety of animals, including birds, but little is known of HEV infection in pet birds in northwest China. …”
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Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease: lessons from animal studies by Wouter Claeys, Anja Geerts, Lien Van Hoecke, Christophe Van Steenkiste, Roosmarijn E. Vandenbroucke

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Animal Models of Steatosis (NAFLD) and Steatohepatitis (NASH) Exhibit Hepatic Lobe-Specific Gelatinases Activity and Oxidative Stress by Giuseppina Palladini, Laura G. Di Pasqua, Clarissa Berardo, Veronica Siciliano, Plinio Richelmi, Stefano Perlini, Andrea Ferrigno, Mariapia Vairetti

“…Gelatinase (MMP-2; MMP-9) activity and protein levels, tissue inhibitors of metalloproteinase (TIMPs), reactive oxygen species (ROS), and thiobarbituric acid-reactive substances (TBARS) were evaluated in the left (LL), median (ML), and right liver (RL) lobes. Serum hepatic enzymes and TNF-alpha were assessed. An increase in gelatinase activity in the NASH model occurred in RL compared with ML. …”
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Long-term outcome in people who use drugs successfully treated for hepatitis C infection with glecaprevir/pibrentasvir by Shana Yi, David Truong, Brian Conway

“…Background: Several clinical trials, including the recently published the GRAND PLAN study from Vancouver Infectious Diseases Center (VIDC), have demonstrated the efficacy of hepatitis C (HCV) therapy among active drug users, including those facing significant addiction-related and social challenges. …”
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Acute Cholestatic Hepatitis A Virus Infection Presenting with Hemolytic Anemia and Renal Failure: A Case Report by Robert T. Lapp, Fedja Rochling

“…Hepatitis A virus is the most common acute viral hepatitis worldwide with approximately 1.5 million cases annually. …”
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Gamma-Glutamyl Transpeptidase-to-Platelet Ratio Predicts Significant Liver Fibrosis of Chronic Hepatitis B Patients in China by Tianyi Ren, Huan Wang, Ruihong Wu, Junqi Niu

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Liver Injury Patterns and Hepatic Toxicity among People Living with and without HIV and Attending Care in Urban Uganda by Clara Wekesa, Rosalind Parkes-Ratanshi, Gregory D. Kirk, Ponsiano Ocama

“…Increasing age was associated with cholestatic liver injury among participants with HIV (OR=2.3 CI (1.0-5.3); p=0.038). Despite a high hepatitis B prevalence among participants with HIV, there was no association with liver injury. …”
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Serum Levels of IL-33 and Correlation with IL-4, IL-17A, and Hypergammaglobulinemia in Patients with Autoimmune Hepatitis by Ma Liang, Zhang Liwen, Zhuang Yun, Ding Yanbo, Chen Jianping

“…This study investigated the role of IL-33 in the pathogenesis of autoimmune hepatitis (AIH). The levels of IL-33/sST2 and Th1/Th2/Th17-type cytokines were determined by enzyme-linked immunosorbent assay in serum samples obtained from 30 AIH patients and 20 healthy controls (HCs). …”
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An Outbreak of Hepatic Veno-Occlusive Disease in Western Afghanistan Associated with Exposure to Wheat Flour Contaminated with Pyrrolizidine Alkaloids by Faizullah Kakar, Zarif Akbarian, Toby Leslie, Mir Lais Mustafa, John Watson, Hans P. van Egmond, Mohammad Fahim Omar, Jawad Mofleh

“…Pyrrolizidine alakloids (PAs) are known to cause hepatic veno-occlusive disease (VOD). Outbreaks have occurred in Western Afghanistan since 1974, the latest in February 2008. …”
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Infiltration of the liver by cells of innate and adaptive immunity and their destruction in development of experimental immune concanavalin-A-induced hepatitis by S. I. Pavlovich, T. M. Bryzgina, N. V. Makogon, L. I. Aleksyuk, T. V. Martynova, R. I. Yanchy, I. N. Alekseyeva

Subjects: “…experimental immune hepatitis…”
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Noninvasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B or C by Contrast-Enhanced Magnetic Resonance Imaging by René Hako, Pavol Kristian, Peter Jarčuška, Ivana Haková, Ivana Hockicková, Ivan Schréter, Martin Janičko

“…We evaluate the utility of hepatocyte-phase Gadoxetate disodium–enhanced magnetic resonance (MR) imaging in staging hepatic fibrosis and compare it with histological analysis as the reference standard (liver biopsy). …”
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Therapeutic effects of reduced glutathione on liver function, fibrosis, and HBV DNA clearance in chronic hepatitis B patients by Qiyao Wei, Jing Zhao

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Cordycepin Protects against Hepatic Ischemia/Reperfusion Injury via Inhibiting MAPK/NF-κB Pathway by Jiameng Ding, null WenjuanYang, Yuhui Jiang, Jie Ji, Jie Zhang, Liwei Wu, Jiao Feng, Yuanyuan Zheng, Yan Li, Ziqi Cheng, Qiang Yu, Jianye Wu, Jingjing Li, Kan Chen, Chuanyong Guo

“…Hepatic ischemia/reperfusion injury (HIRI) is a common complication of liver surgery requiring hepatic disconnection, such as hepatectomy and liver transplantation. …”
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Occult Hepatitis B Infection among Hemodialysis Patients in Tabriz, Northwest of Iran: Prevalence and Mutations within the S Region by Narges Eslami, Vahdat Poortahmasebi, Javid Sadeghi, Reza Ghotaslou, Bahram Niknafs, Hossein Bannazadeh Baghi, Mahin Ahangar Oskouee

“…Regardless of the extensive screening for the detection of hepatitis B surface antigen (HBsAg), hemodialysis (HD) patients are still severely at the risk of occult hepatitis B virus infection (OBI), especially in developing countries. …”
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Fructose Consumption in Pregnancy and Associations with Maternal and Offspring Hepatic and Whole-Body Adiposity in Rodents: A Scoping Review by Grace Zhao, Sarah Chondon, Clint Gray, Sheridan Gentili, Meagan Stanley, Timothy RH Regnault

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Metallothionein 1B attenuates inflammation and hepatic steatosis in MASH by inhibiting the AKT/PI3K pathway by Canghai Guan, Xinlei Zou, Wujiang Shi, Jianjun Gao, Chengru Yang, Yifei Ge, Zhaoqiang Xu, Shaowu Bi, Xiangyu Zhong

“…In vivo experiments demonstrate that specific downregulation of hepatic MT1B expression via AAV8-shMT1B injection significantly increases triglyceride and total cholesterol levels, exacerbates lipid accumulation, and markedly elevates liver fibrosis and inflammatory factor expression. …”
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Barriers to and impacts of hepatitis C treatment among people who inject drugs in Kenya: A qualitative study. by Hannah N Manley, Lindsey R Riback, Mercy Nyakowa, Matthew J Akiyama, Peter Cherutich, John Lizcano, Ann Kurth, Abbe Muller

“…Hepatitis C (HCV) disproportionately affects people who inject drugs (PWID). …”
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Pathological Microenvironment‐Remodeling Nanoparticles to Alleviate Liver Fibrosis: Reversing Hepatocytes‐Hepatic Stellate Cells Malignant Crosstalk by Ling‐Feng Zhang, Wen‐Qi Deng, Xing‐Huan Wang, Qing‐Wen Huang, Su‐Qing Liang, Ze‐Quan Ding, Liang Qi, Yi Wang, Tian‐Jiao Zhou, Lei Xing, Jai‐Woo Lee, Yu‐Kyoung Oh, Hu‐Lin Jiang

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