Metabolic Characteristics of Oxcarbazepine (®Trileptal) and their Beneficial Implications for Enzyme Induction and Drug Interactions by Johann W. Faigle, Guenter P. Menge

“…Hepatic oxygenases of the cytochrome P-450 family play a major role in the clearance of various anti-epileptic drugs. …”
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Overview of hepatocarcinogenesis focusing on cellular origins of liver cancer stem cells: a narrative review by Jong Ryeol Eun

“…Additionally, the cellular origins of liver CSCs are reviewed, emphasizing hematopoietic and mesenchymal stem cells, along with the well-known hepatocytes and hepatic progenitor cells.…”
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Genetic Risk Factors for Metabolic Dysfunction-Associated Steatotic Liver Disease by Yiying Pei, George Boon-Bee Goh

“…These genetic variants play crucial roles in lipid droplet remodeling, secretion of hepatic very low-density lipoprotein and lipogenesis, and understanding the biology has brought new insights to this field. …”
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Variations of Gastrocolic Trunk of Henle and Its Significance in Gastrocolic Surgery by Yuan Gao, Yun Lu

“…In the isolation of subpyloric area or hepatic flexure of the colon for gastrectomy or right hemicolectomy, lymph node dissection and ligation are often performed at the head of the pancreas and superior mesenteric vein, during which even a minor inadvertent error may lead to unwanted bleeding. …”
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A Potential Dubin-Johnson Syndrome Imaging Agent: Synthesis, Biodistribution, and MicroPET Imaging by Jeongsoo Yoo, David E. Reichert, Joonyoung Kim, Carolyn J. Anderson, Michael J. Welch

“…In normal rats, the radioactive copper complex was cleared quickly from the body exclusively through the hepatic pathway. The 64 Cu complex was taken up rapidly by the liver and quickly excreted into the small intestine and then the upper large intestine, whereas < 1% ID/organ was found in the kidney at all time points post injection. …”
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NK Cell Subtypes as Regulators of Autoimmune Liver Disease by Guohui Jiao, Bangmao Wang

“…NK cells act as a “two-edged weapon” and even play opposite roles with both regulatory and inducer activities in the hepatic environment. That is, NK cells act not only to produce inflammatory cytokines and chemokines, but also to alter the proliferation and activation of associated lymphocytes. …”
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Impact of Exposure to Fenitrothion on Vital Organs in Rats by Rasha Abdel-Ghany, Ebaa Mohammed, Shimaa Anis, Waleed Barakat

“…Our results have shown deterioration in liver function as evidenced by the elevation in serum ALT, AST, ALP, and bilirubin and reduction in albumin and hepatic glycogen. This was associated with a state of hyperglycemia and hyperlipidemia and increased prothrombin time, while hemoglobin content was reduced. …”
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A Comprehensive Updated Review of Pharmaceutical and Nonpharmaceutical Treatment for NAFLD by Newaz Hossain, Pushpjeet Kanwar, Smruti R. Mohanty

“…Nonalcoholic fatty liver (NAFL) is at one end and consists of simple hepatic steatosis. On the contrary, nonalcoholic steatohepatitis (NASH) consists of steatosis, inflammation, and ballooning degeneration and can progress to cirrhosis. …”
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Artificial Intelligence and Radiomics in Cholangiocarcinoma: A Comprehensive Review by Marta Zerunian, Tiziano Polidori, Federica Palmeri, Stefano Nardacci, Antonella Del Gaudio, Benedetta Masci, Giuseppe Tremamunno, Michela Polici, Domenico De Santis, Francesco Pucciarelli, Andrea Laghi, Damiano Caruso

“…Cholangiocarcinoma (CCA) is a malignant biliary system tumor and the second most common primary hepatic neoplasm, following hepatocellular carcinoma. …”
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Mesenchymal Hamartoma in Children: A Diagnostic Challenge by Muhammad Rehan Khan, Larry A. Binkovitz, Thomas C. Smyrk, D. Dean Potter, Katryn N. Furuya

“…A computed tomography (CT) scan done for evaluation of his persistent abdominal pain demonstrated a hepatic mass. Follow-up magnetic resonance imaging (MRI) of the liver demonstrated multiple serpiginous tubular-type structures, read as possible Caroli syndrome. …”
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A Turner Syndrome Patient Carrying a Mosaic Distal X Chromosome Marker by Roberto L. P. Mazzaschi, Juliet Taylor, Stephen P. Robertson, Donald R. Love, Alice M. George

“…A skin sample from a 17-year-old female was received for routine karyotyping with a set of clinical features including clonic seizures, cardiomyopathy, hepatic adenomas, and skeletal dysplasia. Conventional karyotyping revealed a mosaic Turner syndrome karyotype with a cell line containing a small marker of X chromosome origin. …”
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Choline Deficiency Attenuates Body Weight Gain and Improves Glucose Tolerance in ob/ob Mice by Gengshu Wu, Liyan Zhang, Tete Li, Gary Lopaschuk, Dennis E. Vance, René L. Jacobs

“…Increased adipose lipolytic activity, decreased plasma glucagon and reduced expression of hepatic glucagon receptor were also observed with the choline-deficient diet. …”
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Quantitative ultrasound rating of liver fibrosis in children with cystic fibrosis by G. M. Dvoryakovskaya, O. I. Simonova, S. A. Ivleva, I. V. Dvoryakovsky, A. N. Surkov, M. O. Gorbunova, I. E. Smirnov

“…Evaluation of liver parenchyma with the help of traditional ultrasound investigation with assessment of blood flow in portal vessels and celiac trunk allows to determine degree of hepatic fibrosis severity and to reveal initial signs of portal hypertension. …”
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Comprehensive Management of Polycystic Ovary Syndrome: The Role of Metformin in Addressing Metabolic and Endocrine Dysregulation by Martyna Kaźmierczak, Jakub Parys, Agnieszka Mikosińska, Patrycja Kałuziak, Marta Jajaczak, Maciej Mossakowski, Aleksandra Witek, Mateusz Litwin, Stanisław Jesionek

“…Conclusion: The findings highlight metformin's three primary mechanisms of action: enhancing insulin sensitivity, inhibiting hepatic gluconeogenesis, and influencing lipid metabolism. …”
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A Rare Cause of the Cough: Primary Small Cell Carcinoma of Esophagus—Case Report by Erdal Yekeler, Timur Koca, Semra Vural

“…Chest X-ray graphy was normal, and computed tomography of the chest showed multiple mediastinal lymph nodes and hepatic metastases. Her endoscopic examination revealed an endoluminal vegetative mass between 20 cm and 23 cm of her esophagus. …”
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Effect of fermented bee pollen on metabolic syndrome in high-fat diet-induced mice by Sha Yan, Kai Wang, Xiaoying Wang, Aiqun Ou, Feiran Wang, Liming Wu, Xiaofeng Xue

“…After YB intervention in mice for 16 weeks, the effect on alleviating MetS was evaluated based on MetS serum parameters, hepatic oxidant status markers and gut microbial populations. …”
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Recent trends and therapeutic potential of phytoceutical‐based nanoparticle delivery systems in mitigating non‐small cell lung cancer by Adam Haysom‐McDowell, Keshav Raj Paudel, Stewart Yeung, Sofia Kokkinis, Tammam El Sherkawi, Dinesh Kumar Chellappan, Jon Adams, Kamal Dua, Gabriele De Rubis

“…Medicinal plants, used for centuries, are traditionally processed by methods such as boiling and oral ingestion, However, water solubility, absorption, and hepatic metabolism reduce phytoceutical bioavailability. …”
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IAPSM’s Position Paper on Pneumococcal Vaccine (PCV) for Adult Immunization in India by Chythra R. Rao, Veena G. Kamath, Anuradha Nadda, Swayam P. Parida, Nikita Sharma, Kapil Goel, Ranjitha S. Shetty, Madhur Verma, Arvind Kumar Singh, Abhisek Mishra, Swosti Kiran, Lalit Sankhe, Madhu Gupta

“…Pneumococcal vaccination is suggested for people aged 19–64 years with immunosuppression, chronic cardiac, lung and hepatic disease, impaired splenic function, uncontrolled diabetes mellitus, current smokers, and those abusing alcohol. …”
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Acute Liver Failure Caused by ‘Fat Burners’ and Dietary Supplements: A Case Report and Literature Review by Y Radha Krishna, V Mittal, P Grewal, MI Fiel, T Schiano

“…The present report describes a young healthy woman who presented with fulminant hepatic failure requiring emergent liver transplantation caused by a dietary supplement and fat burner containing usnic acid, green tea and guggul tree extracts. …”
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(+)-Z-Bisdehydrodoisynolic Acid Enhances Basal Metabolism and Fatty Acid Oxidation in Female Obese Zucker Rats by William J. Banz, April D. Strader, Kolapo M. Ajuwon, Yuqing Hou, Cal Y. Meyers, Jeremy E. Davis

“…We also observed a marked reduction in respiratory quotient (RQ) along with a corresponding induction of hepatic AMPK in rodents provided (+)-Z-BDDA. Collectively, these findings indicate that (+)-Z-BDDA partially attenuated obesity and associated pathologies through increased resting energy expenditure and fatty acid utilization. …”
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