Probiotics for Alleviating Alcoholic Liver Injury by Zelin Gu, Yanlong Liu, Shumeng Hu, Ying You, Jiaqi Wen, Wancong Li, Yuhua Wang

“…Probiotics also increase fatty acid β-oxidation and reduce lipogenesis, combating alcohol-induced hepatic steatosis. In this review, we summarize the current knowledge regarding the mechanism of action of probiotics for reducing the effects of alcoholic liver disease.…”
Get full text

Glucagon like peptide-1 (GLP-1) agonists and cardiometabolic protection: historical development and future challenges by Francisco Westermeier, Enrique Z. Fisman

“…This editorial synthesizes key milestones, from the discovery of GLP-1 to recent clinical trials highlighting the pleiotropic effects of GLP-1RAs in addressing the interconnected spectrum of cardiometabolic conditions, with a focus on cardiovascular, renal, and hepatic benefits. In addition, as GLP-1RAs continue to reshape the management of cardiometabolic disease and global public health, we discuss future challenges to better elucidate their mechanisms of cardiometabolic protection and maximize their therapeutic potential. …”
Get full text

Effect of adipose tissue deposition on insulin resistance in middle‐aged and elderly women: Based on QCT and MRI mDIXON‐Quant by Ying Liu, Lei Gao, Mengfei Wu, Boyang Yang, Dongxue Ren, Zekun Zhang, Wei Zhang, Yan Wang

“…Early identification and active treatment of adipose tissue deposition, especially hepatic fat deposition, may reserve and delay the progression of IR and even metabolic syndrome.…”
Get full text

Effects of Dietary Vitamin C on the Growth Performance, Biochemical Parameters, and Antioxidant Activity of Coho Salmon Oncorhynchus kisutch (Walbaum, 1792) Postsmolts by Cong-mei Xu, Hai-rui Yu, Ling-yao Li, Min Li, Xiang-yi Qiu, Xiao-qian Fan, Yan-lin Fan, Ling-ling Shan

“…Results showed that VC markedly improved the growth performance indexes and liver VC concentration, enhanced the hepatic and serum antioxidant activities, and increased the contents of serum alkaline phosphatase (AKP) activity, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and total cholesterol (TC) whereas decreased the serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) activities, and triglyceride (TG) level. …”
Get full text

Long-Term and Short-Term Effects of Hemodialysis on Liver Function Evaluated Using the Galactose Single-Point Test by Yi-Chou Hou, Wen-Chih Liu, Min-Tser Liao, Kuo-Cheng Lu, Lan Lo, Heng-Chih Pan, Chia-Chao Wu, Oliver Yoa-Pu Hu, Hung-Shang Tang

“…Since the metabolism of galactose is dependent on liver blood flow and hepatic functional mass, further studies are needed.…”
Get full text

Total Hip Lithiasis: A Rare Sequelae of Spilled Gallstones by Vineet Tyagi, Daniel H. Wiznia, Adrian K. Wyllie, Kristaps J. Keggi

“…One potential complication, the spillage of gallstones into the peritoneal cavity, can form a nidus for infection and may be associated with hepatic, retroperitoneal, thoracic, and abdominal wall abscesses. …”
Get full text

Hemothorax Caused by Liver Biopsy – Rare Iatrogenic Complication by Diana Samiatina-Morkūnienė, Rūta Silickytė, Gabija Jankauskaitė

“… Liver biopsy is the most accurate interventional procedure to diagnose hepatic diseases. According to the information provided by the Institute of Hygiene, 968 percutaneous liver biopsies were performed in Lithuania in 2022. …”
Get full text

Critical Illness Associated Fatal Hypoglycemia in a Nondiabetic Male by Amit Toor, Anika Toor, Mahesh Krishnamurthy

“…This, along with reduced hepatic and renal gluconeogenesis seen in preexisting liver and renal disease, can cumulate to life-threatening hypoglycemia and is seen as a poor prognostic factor in the ICU setting.…”
Get full text

Biliothoracic Fistula after Microwave Ablation of Liver Metastasis : Literature Review by Valentina Tassi, Claudia Mosillo, Massimiliano Mutignani, Roberto Cirocchi, Mark Ragusa, Sergio Bracarda, Giovanni Passalacqua, Gabriele Marinozzi, Massimiliano Allegritti

“…Microwave ablation is a safe and effective interventional approach, widely used in the treatment of unresectable primary or metastatic hepatic lesions. Thoracobiliary fistula is a rare postablation complication that can be treated with a conservative or surgical approach. …”
Get full text

Radiographically Occult Carcinomatous Spread of Breast Cancer to the Liver: A Challenging Case by Trish Millard, Akriti Gupta, Christiana Brenin, Paul Marshall, Patrick Dillon

“…Metastatic carcinomatosis to the liver is a pattern of malignant infiltration that tends to provoke hepatic fibrosis. It is a rare complication of multiple solid tumor types and often seen in the absence of discrete tumor mass in the liver. …”
Get full text

Ulcerative Colitis Preceding Asymptomatic Wilson’s Disease: A Case Report and Literature Review by Jun Kunizaki, Yuko Yoto, Yoshinobu Nagaoka, Akira Ishii, Tomoe Kazama, Kohei Wagatsuma, Noriyuki Akutsu, Aki Ishikawa, Toju Tanaka, Shintaro Sugita, Takeshi Tsugawa, Hiroshi Nakase

“…Mutations or defective functions of ATP7B lead to hepatic dysfunction and intestinal inflammation.…”
Get full text

Malaria and an Amoebic Abscess in a Returning Traveler from Liberia by Mhd Mustafa Albitar, Nafiza Martini, Sandy Alkhalil, Tamim Alsuliman, Ali Alrstom

“…Herein, we propose that the relationship between Malaria and amoebic liver abscesses should be explored by researching the effects of malaria on ferritin levels and the immune components in the liver and whether it helps the emergence of hepatic amoebic abscesses or not.…”
Get full text

Enantioseparation of Secnidazole by High-Performance Liquid Chromatography Using Amylose-Based Stationary Phase by Ana C. Nascimento, Rafael F. Perna, Marco A. Cremasco, Cesar C. Santana

“…The secnidazole, a drug used in hepatic amebiasis, giardiasis and bacterial vaginosis, was enantioseparated on a semi-preparative scale by high performance liquid chromatography (HPLC), using chiral stationary phase (CSP) containing amylose tris (3, 5-dimethylphenyl) carbamate on silica gel (Chiralpak® AD). …”
Get full text

An Alarming Mimicry of Intra-Abdominal Infections: Acute Appendiceal Diverticulitis by Youseung Kim, Varun Kesar, Douglas Grider, Maithili V. Chitnavis

“…Abdominal imaging illustrated small bowel enteritis, ascites in both paracolic gutters, and incidental hepatic steatosis. Although ascites fluid demonstrated high neutrophil count consistent with peritonitis and the patient received adequate antibiotics, she clinically deteriorated. …”
Get full text

The effects of Bifidobacterium animalis QC08 on reducing uric acid level and providing renal protection in mice with hyperuricemia by Huijia Mao, Yang Fan, Fang Tan, Xingyao Long

“…Pathological changes in renal tissue were examined through hematoxylin–eosin (HE) staining.ResultsIn vivo experimental results indicated that compared with the normal group, the serum UA, Cr, and BUN levels, as well as the levels of inflammatory factors (TNF-α and IL-1β), and the activities of hepatic xanthine oxidase (XOD) and adenosine deaminase (ADA) were significantly elevated in the control group (p < 0.05). …”
Get full text

STUDY OF THE EFFECT OF METHIONINE HYPERHOMOCYSTEINEMIA AND ITS CORRECTION WITH CHOLINE AND VITAMIN D ON THE CONDITION OF THE PERIODONTIUM, SMALL INTESTINE, AND LIVER OF RATS by Oleh Kutelmakh, Yulia Chumakova, Lina Kovalchuk, Yulia Odnorih, Olexandra Kutelmakh, Anastasiya Spodaruk

“…In recent years, there have been reports of a clinical relationship between periodontitis, intestinal and liver diseases of the human body, the so-called "oral-intestinal-hepatic axis", although the causal mechanism of such an "association" is still unclear. …”
Get full text

Assessing clenbuterol’s modulation of metabolic and inflammatory pathways in Nile tilapia (Oreochromas niloticous) fed high fat diet by Aya G. Rashwan, Doaa H. Assar, Abdallah S. Salah, Muyassar H. Abualreesh, Shimaa M. R. Salem, Norah Althobaiti, Zizy I. Elbialy

“…The results revealed that compared to the control group, HFD exhibited a marked reduction in FBW, BWG, PER, and body protein percent but significantly increased the FCR, IPF, liver fat percent, and body ash percent with altered hematological parameters, raised serum biomarkers of hepatic and renal injury. HFD signally raised mRNA expression of pro-inflammatory cytokines, and declined nrf2 and antioxidative function-related genes. …”
Get full text

Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes by Aniela Skrzypczyk, Stephanie Kehr, Ilona Krystel, Stephan H. Bernhart, Shibashish Giri, Augustinus Bader, Peter F. Stadler

“…Recent advances in the stem cell field allow to obtain many human tissues in vitro. However, hepatic differentiation of induced pluripotent stem cells (iPSCs) still remains challenging. …”
Get full text

Streptococcus anginosus Pyogenic Liver Abscess following a Screening Colonoscopy by Francis Bonenfant, Étienne Rousseau, Paul Farand

“…A previously healthy 58-year-old man presented with a septic thrombosis of the right hepatic vein and a pyogenic liver abscess (PLA) one week after undergoing a screening colonoscopy. …”
Get full text

Ehrlichiosis in a Recent Liver Transplant Recipient Leading to Multiorgan Failure by Fawwaz Almajali, Catherine Oleary, Taylor Hallcox, Justin Lok, Daniela Hermelin, Alexis Guenette, Mustafa Nazzal

“…The patient did recover from infection but not before it manifested in hepatic, renal, and pulmonary involvement. Therefore, a high level of suspicion is necessary for early detection and treatment initiation to prevent a devastating progression of the disease in immunosuppressed patients.…”
Get full text