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2221
Common variable immunodeficiency: An uncommon cause of bronchiectasis, granulomatous disease, chronic liver disease, and enteropathy – Case report and review of literature
Published 2020-01-01“…Nearly 20%–25% of cases develop autoimmune complications such as autoimmune hemolytic anemia and immune thrombocytopenia. Hepatic involvement can occur in the form of abnormal biochemistry, nodular degenerative hyperplasia, and cirrhosis of liver. …”
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2222
Role of the Surgical Method in Development of Postoperative Cholangiocarcinoma in Todani Type IV Bile Duct Cysts
Published 2015-01-01“…Radical resection of both intra- and extrahepatic cysts combined with hepatic resection and Roux-en-Y hepaticojejunostomy is associated with a reduced risk of subsequent cancer development. …”
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2223
Metabolic and hematological disruptions induced by Diphenyl Diselenide in male wistar rats
Published 2024-12-01“…The resultant increased gluconeogenesis and hepatic glycogen storage could be a detoxification mechanism whereby excess lactate due to increased glycolysis is converted to a non-toxic and neutral glucose to maintain pH balance in order to preserve the animals against DPDS toxicity.…”
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2224
Role of High-Density Lipoprotein Cholesterol (HDL-C) as a Clinical Predictor of Decompensation in Patients with Chronic Liver Disease (CLD)
Published 2021-01-01“…Each patient was carefully followed up for development of decompensation events such as new-onset/worsening ascites, hepatic encephalopathy, or variceal bleed during follow-up. …”
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2225
Manganese Neurotoxicity as a Complication of Chronic Total Parenteral Nutrition
Published 2020-01-01“…Our objective in presenting this case is to highlight manganese neurotoxicity as a rare complication of TPN in a patient without known hepatic dysfunction and to emphasize the importance of routinely monitoring patients for the possible adverse effects of chronic TPN. …”
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2226
Protective Effects of Garlic and Cinnamon Oils on Hepatocellular Carcinoma in Albino Rats
Published 2019-01-01“…The HCC-induced group showed a significant decrease in the body mass and a significant elevation in the liver weight, alpha-fetoprotein (AFP), liver enzymes, hepatic malondialdehyde (MDA), and p53 protein expression levels as well as genetic mutations in intron 5 of p53 gene in the form of Single-Nucleotide Polymorphisms (SNPs) and insertions. …”
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2227
Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents
Published 2024-01-01“…LBDDSs overcome the shortcomings that are associated with antihypertensive agents because around fifty percent of the antihypertensive agents experience a few drawbacks including short half-life because of hepatic first-pass metabolism, poor aqueous solubility, low permeation rate, and undesirable side effects. …”
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2228
Macrofilaricidal Activity, Acute and Biochemical Effects of Three Lichen Species Found on Mount Cameroon
Published 2022-01-01“…These two most active extracts had no significant effect on liver enzymes, alanine aminotransferase, and aspartate (P values < 0.05), but a high AST : ALT ratio (2.59) for Pammet indicates likely reversible adverse hepatic toxicity. The high macrofilaricidal activity and selectivity of P. tinctorum suggest it is a potential source of new macrofilaricides which should be further investigated to identify its bioactive constituents.…”
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2229
Diabetes-Resistant NOR Mice Are More Severely Affected by Streptozotocin Compared to the Diabetes-Prone NOD Mice: Correlations with Liver and Kidney GLUT2 Expressions
Published 2015-01-01“…We also detected GLUT2 expression profiles in NOD and NOR hepatic and renal tissues by western blot analysis and observed considerably higher GLUT2 expression levels in liver and kidney tissues of NOR mice. …”
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2230
The Effect of Endotoxin-Induced Inflammation on the Activity of the Somatotropic Axis in Sheep
Published 2024-01-01“…It can suppress growth and hepatic metabolism to spare energy expenditure.…”
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2231
Disparate Intent-to-Treat Outcomes for Pediatric Liver Transplantation Based on Indication
Published 2023-01-01“…The Kaplan–Meier method and log-rank test were used to assess differences in waitlist, post-transplant, and intent-to-treat mortality among the top 5 indications of biliary atresia, acute hepatic necrosis, metabolic disorders, hepatoblastoma, and autoimmune cirrhosis. …”
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2232
Prophylactic Role of Averrhoa carambola (Star Fruit) Extract against Chemically Induced Hepatocellular Carcinoma in Swiss Albino Mice
Published 2014-01-01“…These results demonstrate that ACE prevents the DENA/CCl4 induced adverse physical and biochemical alterations during hepatic carcinogenesis in mice. This study suggests the prophylactic role of Averrhoa carambola against hepatocellular carcinoma in mice; therefore, it could be employed for the further screening as a good chemopreventive natural supplement against cancer.…”
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2233
Toxicological Evaluation and Protective Effects of Ethanolic Leaf Extract of Cassia spectabilis DC on Liver and Kidney Function of Plasmodium berghei-Infected Mice
Published 2022-01-01“…Regarding hepatomegaly, further plasma levels of hepatic enzyme were analyzed, as well as histopathological observation of the liver to determine the effect of the extract on liver. …”
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2234
The perfect molecule for hormonal contraception: Estetrol benefits. A review
Published 2024-12-01“…During E4 therapy, the risk of venous thromboembolism is minimized, and there is less impact on hepatic enzymes, which improves the quality of sexual life and opens up the opportunities of prescribing COCs with E4 to women who are continuously receiving other drugs – statins, antiretroviral agents, or anticonvulsants. …”
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2235
A bioinformatic approach to characterize the vitellogenin receptor and the low density lipoprotein receptor superfamily in the newt Cynops orientalis
Published 2025-01-01“…The secondary structure analyses and the expression profiles obtained from hepatic and gonadal tissues of C. orientalis supported the role of VTGR as vitellogenin oocyte membrane receptor in this species. …”
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2236
Thromboelastometry Identified Alteration of Clot Stabilization and Factor XIII Supplementation Need in a Patient with Decompensated Liver Disease Undergoing Liver Biopsy
Published 2018-01-01“…This clotting disorder was corrected with factor XIII concentrate after unsuccessful administration of antifibrinolytic drugs and hepatic biopsy was performed without hemorrhagic complications. …”
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2237
Evaluation of a modified venous excess ultrasound (VExUS) protocol for estimation of venous congestion: a cohort study
Published 2025-01-01“…Venous Excess Ultrasound Score (VExUS) is a novel ultrasound protocol for to assessment of venous congestion using the inferior vena cava, hepatic, portal and renal veins. Though there is a much interest in the technique, the renal component of the exam is challenging to acquire. …”
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2238
Dietary Valine Requirement of Juvenile Olive Flounder (Paralichthys olivaceus)
Published 2024-01-01“…Relatively lower lipid droplet in hepatic cell was observed in 4 g/kg Val group. Our findings suggested that dietary Val requirements for juvenile olive flounder would be 17.7–18.9 g Val/kg (35.4–37.8 g/kg on the basis of crude protein), estimated by quadratic regression analysis based on the weight gain, protein efficiency ratio, and protein retention efficiency.…”
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2239
Spleen and Liver Stiffness Evaluation by ARFI Imaging: A Reliable Tool for a Short-Term Monitoring of Portal Hypertension?
Published 2022-01-01“…Background. Assessment of hepatic venous pressure gradient (HVPG) is the most reliable, though invasive method for evaluation of portal hypertension. …”
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2240
Effect of Global ATGL Knockout on Murine Fasting Glucose Kinetics
Published 2015-01-01“…The glucose 13C-isotopomer distributions in both ATGL−/− and control mice were consistent with extensive hepatic pyruvate recycling. This suggests that gluconeogenic outflow from the Krebs cycle was also well compensated in ATGL−/− mice.…”
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