Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl4-) Induced Liver Injury in Mice by Sura Wanessa Santos Rocha, Maria Eduarda Rocha de França, Gabriel Barros Rodrigues, Karla Patrícia Sousa Barbosa, Ana Karolina Santana Nunes, André Filipe Pastor, Anne Gabrielle Vasconcelos Oliveira, Wilma Helena Oliveira, Rayana Leal Almeida Luna, Christina Alves Peixoto

“…Based on the results of the present study, DEC can be used as a potential anti-inflammatory drug for chronic hepatic inflammation.…”
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Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways by Ning Liu, Jiao Feng, Xiya Lu, Zhilu Yao, Qing Liu, Yang Lv, Yuru Han, Jingfan Deng, Yingqun Zhou

“…Methods. Mouse models of hepatic fibrosis were established by intraperitoneal injection of carbon tetrachloride (CCl4) or bile duct ligation (BDL). …”
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Murine model evaluation of biochemical and tissue-damage induced by Bothrops asper (Nauyaca) snake venom by Dr. Carlos Gallardo-Casas Ángel Gallardo-Casas, María Teresa Valadez-Omaña, Emmanuel Correa Solís, María del Carmen Castillo-Hernández, Rocio Ortiz-Butron

“…Objective: To evaluate, in a mouse model, the effect of Bothrops asper venom snake on liver enzymes LDH, AST, and ALT, as well as to assess its effect on renal and hepatic histology. Methods: The LD50 was determined using a dose-response curve after intramuscular administration of increasing doses of the venom to mice (0.5, 1, 2.5, 5, and 10 mg of protein/kg). …”
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Collagen fibers quantification for liver fibrosis assessment using linear dichroism photoacoustic microscopy by Yang Qiu, Honghui Li, Kun Yu, Jiali Chen, Li Qi, Yinghua Zhao, Liming Nie

“…Liver fibrosis represents a progressive pathological condition that can culminate in severe hepatic dysfunction, potentially advancing to cirrhosis and liver cancer. …”
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Anatomical Variations of Cystic Ducts in Magnetic Resonance Cholangiopancreatography and Clinical Implications by Radha Sarawagi, Shyam Sundar, Sanjeev K. Gupta, Sameer Raghuwanshi

“…In 1 case, CD was draining into right hepatic duct. Congenital cystic dilation of CD was noted in one case with evidence of type IV choledochal cyst. …”
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Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD by Adil Mardinoglu, Elias Bjornson, Cheng Zhang, Martina Klevstig, Sanni Söderlund, Marcus Ståhlman, Martin Adiels, Antti Hakkarainen, Nina Lundbom, Murat Kilicarslan, Björn M Hallström, Jesper Lundbom, Bruno Vergès, Peter Hugh R Barrett, Gerald F Watts, Mireille J Serlie, Jens Nielsen, Mathias Uhlén, Ulf Smith, Hanns‐Ulrich Marschall, Marja‐Riitta Taskinen, Jan Boren

“…Quantification of the hepatic expression levels of the associated enzymes further pointed to altered de novo GSH synthesis. …”
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Prenatal Diagnosis of Congenital Mesenchymal Hamartoma of Liver: A Case Report by Sreelakshmi Kodandapani, Muralidhar V. Pai, Vijay Kumar, Kanthilatha V. Pai

“…Hepatic mesenchymal hamartoma is a rare benign tumor. …”
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Clinical Practice Guidelines for Severe Sepsis Treatment. by Julio Héctor Jova Dueñas, Diosdania Alfonso Falcón, Marcos Diosdado Iraola Ferrer, Inti Santana Carballosa, José Noel Marrero.

“…It is a syndrome of inflammatory systemic response caused by documented infection (clinical and/or microbiological), associated with organic dysfunction (respiratory, renal, hepatic, cardiovascular, haematological and neurological), hypotension or hypoperfusion. …”
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Regulation of glycolipid and amino acid metabolism in juvenile triploid crucian carp (Carassius auratus) by oral administration of aspartic acid by Yu Wang, Bo Dong, Liyun Wu, Dong Han, Xiaoming Zhu, Haokun Liu, Yunxia Yang, Shouqi Xie, Zhen Liu, Junyan Jin

“…Additionally, the gene expression level and enzymatic activity of hepatic aspartate aminotransferase were increased (P < 0.05). …”
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Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series by Magdalena Antoszewska, Piotr Spychalski, Gerda Elisabeth Villadsen, Niels Kristian Muff Aagaard

“…Pruritus that is refractory to pharmacological treatment may be an indication for liver transplantation [1–3]. Pathogenesis of hepatic pruritus is still not fully understood. However, it is probably associated with the accumulation of pruritogens in plasma and other tissues as a result of cholestasis [4] (bile salts, bile acids, progesterone metabolites, lysophosphatidic acid, endogenous opioids [1]).…”
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Case of Massive Hydatid Pulmonary Embolism Incidentally Discovered in a 56-Year-Old Woman with Posttraumatic Abdominal Pain by Zied Mezgar, Mariem Khrouf, Houda Ben Soltane, Mohamed Mahjoub, Sihem Ben Fredj, Amel Amara, Maher Jedidi, Samar Hajer Sandid, Sarra Zaouali, Ines Waz, Asma Saada, Mehdi Methamem

“…We report a case with pulmonary hydatidosis resulting in a massive bilateral pulmonary embolism in a 56-year-old woman with history of hepatic echinococcosis. A brief overview of clinical features and radiologic findings is presented.…”
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Primary Small Cell Carcinoma of the Larynx: Report of a Rare Tumor by Harmeet Singh, Ashok Chauhan

“…We report a case of a 60-year-old patient with small cell carcinoma of the subglottic larynx, who presented with hepatic metastasis.…”
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Exploring and Verifying the Mechanism and Targets of Shenqi Pill in the Treatment of Nonalcoholic Steatohepatitis via Network Pharmacology and Experiments by Beihui He, Zheng Chen, Yunmeng Nie, Minmin Luo, Sumei Xu, Junbin Yan, Zhiyun Chen

“…UPLC–MS/MS was used to verify the active compounds of the SQP screened. The hepatic pathology and biochemical indicators of rats were used to judge the modeling results and the curative effect of SQP. …”
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Effects of dietary chlorogenic acid supplementation on laying performance, egg quality, antioxidant capacity, and liver lipid metabolism in late-peak laying hens by Haitong Zhao, Lianxiang Guo, Ming Yan, Yue Sun, Yan Hong, Mingkun Zhu

“…CGA at 600 and 800 mg/kg doses significantly reduced serum hydrogen peroxide and malondialdehyde levels, as well as hepatic malondialdehyde levels. Meanwhile, CGA treatment significantly upregulated hepatic Nrf2 and SOD2 gene expression while downregulating Keap1 gene expression. …”
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MRI-based deep learning radiomics to differentiate dual-phenotype hepatocellular carcinoma from HCC and intrahepatic cholangiocarcinoma: a multicenter study by Qian Wu, Tao Zhang, Fan Xu, Lixiu Cao, Wenhao Gu, Wenjing Zhu, Yanfen Fan, Ximing Wang, Chunhong Hu, Yixing Yu

“…Radiomics and deep learning effectively differentiate the three types of malignant hepatic tumors. The fusion models may enhance clinical decision-making for malignant hepatic tumors. …”
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SLC1A4 Promotes Malignant Transformation of Hepatocellular Carcinoma by Activating the AKT Signaling by Jiaoyun Zheng, Jian Gong

“…Moreover, epithelial–mesenchymal transition (EMT) in vitro and metastasis potential in vivo of hepatic cancer cells was suppressed by the downregulated SLC1A4 level. …”
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Decoding VExUS: a practical guide for excelling in point-of-care ultrasound assessment of venous congestion by Taweevat Assavapokee, Philippe Rola, Nicha Assavapokee, Abhilash Koratala

“…This review article provides practical guidance on performing VExUS, encompassing equipment requirements, preparation, machine settings, and examination techniques for assessing the inferior vena cava (IVC), hepatic vein (HV), portal vein (PV), and intrarenal vein. …”
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A Delayed Diagnosis of Hemorrhagic Shock in a Patient with Alcoholic Cirrhosis and Ascites on Bedside Ultrasound by Madeline Bach, Julian Choi, Rory A. Smith, Sarkis Arabian

“…We present a case of hemorrhagic shock due to splenic and hepatic lacerations diagnosed by bedside paracentesis, initially misclassified as septic shock due to suspected spontaneous bacterial peritonitis (SBP). …”
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Dynamic localization of glucokinase and its regulatory protein in hypothalamic tanycytes. by Magdiel Salgado, Estefanía Tarifeño-Saldivia, Patricio Ordenes, Carola Millán, María José Yañez, Paula Llanos, Marcos Villagra, Roberto Elizondo-Vega, Fernando Martínez, Francisco Nualart, Elena Uribe, María de Los Angeles García-Robles

“…In the present study, GK intracellular localization in hypothalamic and hepatic tissues of the same rats under several glycemic conditions was compared using confocal microscopy and Western blot analysis. …”
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Physiological and pathophysiological actions of insulin in the liver by Naoto Kubota, Tetsuya Kubota, Takashi Kadowaki

“…Impaired insulin receptor signaling can cause hepatic insulin resistance and lead to type 2 diabetes. …”
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