Pharmacological insights and therapeutic advances of mangiferin against various pathological conditions in liver diseases by Tanvir Zaman Shoyshob, Sumaya Akter, Muhammad Ramiz Uddin, Mithila Farjana, Akhi Moni, Wonhyo Seo, Md. Golzar Hossain, Md Jamal Uddin

“…Several studies have suggested that pretreatment with mangiferin decreases hepatic inflammation, oxidative stress, apoptosis, fibrosis, endoplasmic reticulum (ER) stress, and hepatic dysfunction and concomitantly ameliorates the morphological structures of the liver. …”
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Nutritional composition, toxicity, and the effects of Parkia biglobosa on the metabolic, somatic and oxidative parameters related to liver and kidney function of obese rats by Mirela Gouveia-Nhanca, Maria Luiza Rolim Bezerra, Yuri Mangueira do Nascimento, Evandro Ferreira da Silva, Josean Fechine Tavares, Gonçalo Mendes da Conceição, Rubens Teixeira de Queiroz, Luis António Tavares, Adriano Francisco Alves, Jailane de Souza Aquino

“…Background: The pathophysiology of obesity is associated with somatic, metabolic and oxidative changes which can also compromise renal and hepatic function. Treatment of this condition involves dietary intervention, including incorporating foods rich in bioactive compounds such as Parkia biglobosa. …”
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Single-Cell RNA Sequencing Reveals Macrophage Dynamics During MASH in <i>Leptin</i>-Deficient Rats by Xiaoming Xin, Yaohua Ni, Jing Wang, Fenglin Wu, Meichen Liu, Lingjuan Wu, Jiaxing Dai, Chenglin Wu, Xiaolei Song, Wang Zhang, Guangrui Yang, Ruling Shen, Xianmin Zhu

“…In humans and mice, the cellular heterogeneity and diverse function of hepatic macrophages in MASH have been investigated by single cell RNA sequencing (scRNA-seq). …”
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A Rare Case of Spontaneous Cardiac Tamponade Induced by Concomitant Use of Rivaroxaban and Amiodarone by Oreoluwa Oladiran, Jared Segal, Ifeanyi Nwosu, Salik Nazir

“…Both rivaroxaban and amiodarone are substrates for the CYP3A4 hepatic pathway, and concomitant use can result in increased plasma rivaroxaban levels causing an increased propensity to bleeding. …”
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Preoperative predictive factors of cystobiliary fistulas in liver hydatid cysts: results of a monocentric study by Mohamed Salah Jarrar, Ines Karmani, Mehdi Chahed, Malek Barka, Mohamed Hedi Mraidha, Radhouane Toumi, Ameni Beizig, Khayri Dhouioui, Sabri Youssef

“…Introduction The evolution of hepatic hydatid cyst can be enameled with complications, mainly biliary fistula, which can be both symptomatic or occult. …”
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Nitrones: not only extraordinary spin traps, but also good nitric oxide sources in vivo by Croitoru Mircea Dumitru, Petkes Hermina Iulia, Fülöp Ibolya, Cotârlan Remus, Şerban Oana Elena, Dogaru Titica Maria, Gâz Florea Şerban Andrei, Tőkés Béla, Majdik Cornelia

“…At the same time, nitrones do not react with hepatic homogenates, proving that the release of nitric oxide takes place in the tissues and is not related to hepatic metabolism. …”
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Rofecoxib-Induced Hepatotoxicity: A Forgotten Complication of the Coxibs by Brian Yan, Yvette Leung, Stefan J Urbanski, Robert P Myers

“…Although the coxibs are generally well-tolerated, rofecoxib was recently withdrawn from the market due to concerns regarding cardiovascular safety. Rare cases of hepatic injury attributable to the coxibs have been reported. …”
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The Implications of Liver Biopsy Results in Patients with Myeloproliferative Neoplasms Being Treated with Ruxolitinib by Douglas Tremblay, Juan Putra, Alexander Vogel, Adam Winters, Ronald Hoffman, Thomas D. Schiano, Maria Isabel Fiel, John O. Mascarenhas

“…Ruxolitinib is increasingly being utilized for the treatment of myelofibrosis and polycythemia vera, but the potential for hepatic toxicity is poorly understood. We performed a retrospective review of hepatic damage occurring in patients with myeloproliferative neoplasms receiving ruxolitinib. …”
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Modulation of Innate Immunity by G-CSF and Inflammatory Response by LBPK95A Improves the Outcome of Sepsis in a Rat Model by Haoshu Fang, Chuanfeng Hua, Stefanie Weiss, Anding Liu, Wenhui Cheng, Ralf Claus, Jürgen Rödel, Olaf Dirsch, Uta Dahmen

“…G-CSF treatment increased the white blood cell counts, hepatic neutrophil infiltration, and bacterial clearance in the liver, lung, and blood. …”
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Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats by Elin Strand, Vegard Lysne, Mari Lausund Grinna, Pavol Bohov, Asbjørn Svardal, Ottar Nygård, Rolf K. Berge, Bodil Bjørndal

“…Thus, the aim was to compare the metabolic response in hepatic, adipose, and cardiac tissues after treatment with specific PPAR agonists. …”
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Effects of Delta-Like Noncanonical Notch Ligand 1 Expression of Human Fetal Liver Hepatoblasts on Hematopoietic Progenitors by Jörg C. Gerlach, Robert L. Thompson, Bruno Gridelli, Eva Schmelzer

“…Although the hepatic and hematopoietic progenitors of the liver are well characterized, the interactions between these two lineages remain mostly elusive. …”
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Docosahexaenoic and Eicosapentaenoic Acid Supplementation Could Attenuate Negative Effects of Maternal Metabolic Syndrome on Liver Lipid Metabolism and Liver Betacellulin Expressio... by Tomislav Mašek, Petra Roškarić, Sunčica Sertić, Kristina Starčević

“…<b>Background/Objectives</b>: This study investigated the effects of maternal metabolic syndrome during pregnancy on hepatic fatty acid metabolism and betacellulin expression in rat offspring. …”
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Wilson disease in the USA: epidemiology and real-world patient characteristics based on a retrospective observational health claims study by Karl Heinz Weiss, Peter Hedera, Shona Fang, Carey Strader, Halley Costantino

“…Among them, 56.8% had hepatic symptoms, 57.0% neurologic symptoms and 47.4% psychiatric symptoms. …”
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Model of Liver Fibrosis Induction by Thioacetamide in Rats for Regenerative Therapy Studies by Nathaly Enciso, José Amiel, Fredy Fabián-Domínguez, Jhon Pando, Nancy Rojas, Carlos Cisneros-Huamaní, Ernesto Nava, Javier Enciso

“…Hepatic fibrosis is caused by chronic injury due to toxic, infectious, or metabolic causes, and it may progress to cirrhosis and hepatocellular carcinoma. …”
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Systematic review of exercise for the treatment of pediatric metabolic dysfunction-associated steatotic liver disease. by Martha R Smith, Elizabeth L Yu, Ghattas J Malki, Kimberly P Newton, Nidhi P Goyal, Karen M Heskett, Jeffrey B Schwimmer

“…Five of the 11 studies that evaluated hepatic steatosis reported an absolute decrease of 1% to 3%. …”
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Terminalia catappa Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene by Franklyn Nonso Iheagwam, Gaber El-Saber Batiha, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu

“…A significant (p<0.05) upregulation of hepatic TNF-α and IL-6 expression and downregulation (p<0.05) of Nrf-2 expression were observed during diabetes onset. …”
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Surgical Strategy in Patients with Complete Transposition of Internal Organs in Cancer of the Biliopancreatoduodenal Zone by R. V. Ischenko, Yu. V. Ivanov, A. V. Smirnov, V. N. Antipov

“…In addition to the situs vicserum inversus, this patient revealed a special variant of vascular anatomy, namely: separate separation of the left and right hepatic arteries from the ventral trunk. A 70-year-old man, in addition to complete transposition of internal organs, had a combination of cancer of the terminal part of the common bile duct and heterotaxy syndrome in the form of polysplenia, aplasia of the hepatic segment of the inferior vena cava, agenesis of the dorsal pancreatic rudiment (“short” pancreas), intrapancreatic course of the right hepatic artery extending from the superior mesenteric arteries, rotational abnormalities of intestinal development. …”
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Long-Term Suitability of Left Gastric Artery Inflow for Arterial Perfusion of Living Donor Right Lobe Grafts by Judyta A. Lipinska, Johnny Wang, Joseph N. Carey, Aaron A. Ahearn, Yuri S. Genyk

“…At grafting, the risk for later thrombosis is high if a dissected hepatic artery is used for standard reconstruction. …”
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Functional Relationships between Lipid Metabolism and Liver Regeneration by David A. Rudnick, Nicholas O. Davidson

“…Nevertheless, the nature and identities of the most proximal events that initiate hepatic regeneration as well as those distal signals that terminate this process remain unknown. …”
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Cardiac Failure after Liver Transplantation Requiring a Biventricular Assist Device by Rita Jermyn, Eiei Soe, David D’Alessandro, Julia Shin, William Jakobleff, Daniel Schwartz, Milan Kinkhabwala, Paul J. Gaglio

“…Increased hepatic iron load in extrahepatic organs of cirrhotic patients with and without hereditary hemochromatosis portends a poorer long term prognosis after liver transplant. …”
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