Synchronous Diagnosis of Multiple Myeloma, Breast Cancer, and Monoclonal B-Cell Lymphocytosis on Initial Presentation by A. Vennepureddy, V. Motilal Nehru, Y. Liu, F. Mohammad, J. P. Atallah

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Two Cases of Heavy Chain MGUS by Jan Van Keer, Björn Meijers, Michel Delforge, Gregor Verhoef, Koen Poesen

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SDF-1α Facilitates Mesenchymal Stem Cells to Induce Regulatory B Cell Differentiation from Patients with Immune Thrombocytopenia by Zhe Chen, Shufen Zhou, Jianyun Li, Hui Li, Can Huang, Qin Guo, Tiantian Zhang, Bingya Yang, Chuanqing Tu, Chengshan Guo

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Molecular Mechanisms and Therapeutic Prospects of Immunotherapy and Targeted Therapy in Primary Central Nervous System Lymphoma by Lin Zhong MM, Anqing Lu MB, Xiyue Lu MM, Xiaoyin Liu MD, Lujia Cao MM, Shihong Zhu MM, SiJun Diao MM, Xu Cheng MM, Hongwei Wu MB, Jing Chen MD

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Immunomodulatory Effects of 1,25-Dihydroxyvitamin D3 on Dendritic Cells Promote Induction of T Cell Hyporesponsiveness to Myelin-Derived Antigens by Wai-Ping Lee, Barbara Willekens, Patrick Cras, Herman Goossens, Eva Martínez-Cáceres, Zwi N. Berneman, Nathalie Cools

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Knockout IL4I1 affects macrophages to improve poor efficacy of CD19 CAR-T combined with PD-1 inhibitor in relapsed/refractory diffuse large B-cell lymphoma by Rui Zhang, Yi Zhang, Hairong Xiao, Qingxi Liu, Mingfeng Zhao

“…Abstract Chimeric antigen receptor (CAR) T-cell therapy plays a critical role in the treatment of B-cell hematologic malignancies. The combination of PD-1 inhibitors and CAR-T has shown encouraging results in treating patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL). …”
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Racial discrimination among women seeking breast cancer care by Lauren J. Oshry, Ruth I. Lederman, Haley Gagnon, Tsion Fikre, Daniel A. Gundersen, Anna C. Revette, Ashley Odai-Afotey, Olga Kantor, Dawn L. Hershman, Katherine D. Crew, Nancy L. Keating, Rachel A. Freedman, Naomi Y. Ko

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The Effect of Mesenchymal Stem Cell-Derived Exosomes and miR17-5p Inhibitor on Multicellular Liver Fibrosis Microtissues by Farnaz Sani, Mina Soufi Zomorrod, Negar Azarpira, Masoud Soleimani

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Diabetes insipidus and Guillain-Barré-like syndrome following CAR-T cell therapy: a case report by Christian Koch, Patrick Roth, Juliane Fleischer, Todor Popov, Karl Frontzek, Bettina Schreiner, Markus G. Manz, Simone Unseld, Antonia M. S. Müller, Norman F. Russkamp

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Systematic Analysis of E3 Ligase-Related Genes Identified UBE2L3 as a Prognostic Biomarker Associated With Drug Resistance in Acute Myeloid Leukemia by Ling C, Cao N, Wang H, Wan Y, Liang X, Guo J, Xiao M, Zhang Q, Zhai Z

“…Chun Ling,1,2 Nengneng Cao,1 Huiping Wang,1 Yang Wan,1 Xue Liang,1 Jinjing Guo,1 Meng Xiao,1 Qiguo Zhang,2 Zhimin Zhai1 1Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230000, People’s Republic of China; 2Department of Hematology, Affiliated Chuzhou Hospital of Anhui Medical University, First People’s Hospital of Chuzhou, Chuzhou, Anhui, 239001, People’s Republic of ChinaCorrespondence: Zhimin Zhai, Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230000, People’s Republic of China, Email zzzm886@163.comBackground: Acute Myeloid Leukemia (AML) is a prevalent neoplastic disorder. …”
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Impact of DLL3 Expression as Prognostic Factor in Extensive Stage of Small Cell Lung Cancer Treated With First‐Line Chemotherapy by Hohyung Nam, Soon‐Hee Jung, Jii Bum Lee, Jee Hyun Kong, Seungtaek Lim

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The origins of the definition of complete remission in acute myeloid leukemia by Mark R. Litzow

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Transcription factor RUNX1 regulates coagulation factor XIII-A (F13A1): decreased platelet-megakaryocyte F13A1 expression and clot contraction in RUNX1 haplodeficiency by Fabiola Del Carpio-Cano, Natthapol Songdej, Liying Guan, Guangfen Mao, Lawrence E. Goldfinger, Jeremy G.T. Wurtzel, Kiwon Lee, Michele P. Lambert, Mortimer Poncz, A. Koneti Rao

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Interactive effect of phenylalanine with duration of diabetes on the risk of small vessel disease in Chinese patients with T2DM by Jun Zheng, Wei Zhang, Yu-Yang Miao, Xue-Rui Li, Wei-Ming Luo, Xi-Lin Yang, Zhong-Ze Fang, Qiang Zhang

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Effect of nursing interventions on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome (预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察)... by WANG Xue (王雪), CAO Hongjing (曹红京), LI Ning (李宁), CHEN Siyu (陈思雨), REN Lixin (任利鑫), SONG Meijia (宋美佳)

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Advancing treatment choices: CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer by Paola Zagami, Angela Esposito, Beatrice Taurelli Salimbeni, Pier Paolo Maria Berton Giachetti, Roberta Scafetta, Matteo Lambertini, Massimo Di Maio, Giuseppe Curigliano, Carmen Criscitiello, Saverio Cinieri

“…Yet, 49 % of respondents emphasized the need for more real world evidence on CDK4/6i switch safety and efficacy. 96 % of respondents reported discontinuation rates between 0% and 25 % of patients, with constipation and hematological toxicity being the most frequent treatment discontinuation reasons. …”
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Genotype Variations and Association between PAI-1 Promoter Region (4G/5G and -844G/A) and Susceptibility to Acute Myocardial Infarction and Chronic Stable Angina by Sunil Kumar, Amit Kumar Verma, Vinay Sagar, Ravi Ranjan, Rahul Sharma, Preeti Tomar, Deepti Bhatt, Yamini Goyal, Mohammed A. Alsahli, Ahmad Almatroudi, Saleh A. Almatroodi, Arshad Husain Rahmani, Faris Alrumaihi, Khursheed Muzammil, Kapil Dev, Rakesh Yadav, Renu Saxena

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Case report: JAK inhibitor treatment of immune dysregulation symptoms in a patient with PTPN2 deficiency by Anna Roppelt, Ulyana Markina, Irina Beloglazova, Irina Beloglazova, Vasily Parshin, Dmitry Kanner, Dmitry Pershin, Mariia Fadeeva, Elena Raykina, Maxim Aleksenko, Alexander Karaulov, Mariana Lysenko, Mariana Lysenko, Daria Fomina, Daria Fomina, Daria Fomina

“…Thus, according to our experience, JAK inhibitors are able to alleviate the PTPN2 deficiency symptoms, including hematological changes and interstitial lung damage.…”
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Autologous Hematopoietic Cell Transplant as an Effective Treatment Modality for Systemic Sclerosis and Multiple Myeloma by Memon H, Parrondo R, Schreurs J, Ayala E, Iqbal M

“…Hamda Memon,1 Ricardo Parrondo,2 Julianna Schreurs,2 Ernesto Ayala,2 Madiha Iqbal2 1Department of Family Medicine, Geisinger Health in Wilkes Barre, Wilkes Barre, Pennsylvania, USA; 2Division of Hematology and Oncology, Mayo Clinic, Jacksonville, Florida, USACorrespondence: Madiha Iqbal, Department of Medicine,Division of Hematology-Oncology and Blood and Marrow Transplantation Program, Mayo Clinic, 4500 San Pablo road, Jacksonville, FL, 32224, USA, Email Iqbal.madiha@mayo.eduAbstract: Systemic sclerosis (SSc) is a multi-system disease characterized by a dysregulated immune system. …”
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Severe Lactic Acidosis in a Patient with B-Cell Lymphoma: A Case Report and Review of the Literature by Farn Huei Chan, Daniel Carl, Laurel J. Lyckholm

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