Early progression beyond first‐line chemoimmunotherapy in follicular lymphoma: Insights from a Fondazione Italiana Linfoma (FIL) study by Alberto Bavieri, Maria E. Nizzoli, Alessandra Tucci, Vittorio R. Zilioli, Jacopo Olivieri, Benedetta Bianchi, Mansueto G. Rosaria, Ombretta Annibali, Alessia Bari, Gloria M. Casaluci, Michele Cimminiello, Nicola Di Renzo, Federica Cavallo, Vicenzo Pavone, Clara Mannarella, Annalisa Arcari, Maggi Alessandro, Antonella Anastasia, Vittoria Tarantino, Antonino Neri, Massimo Gentile, Fortunato Morabito, Stefano Luminari

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Idiopathic multicentric Castleman disease in children: a single-center retrospective analysis by Junye Du, Jiafeng Yao, Honghao Ma, Li Li, Ang Wei, Liping Zhang, Dong Wang, Zhigang Li, Rui Zhang, Tianyou Wang

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Positively charged cytoplasmic residues in corin prevent signal peptidase cleavage and endoplasmic reticulum retention by Hui Li, Shijin Sun, Wenjun Guo, Lina Wang, Zihao Zhang, Yue Zhang, Ce Zhang, Meng Liu, Shengnan Zhang, Yayan Niu, Ningzheng Dong, Qingyu Wu

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Bone Marrow Endothelial Progenitor Cells remodelling facilitates normal hematopoiesis during Acute Myeloid Leukemia Complete Remission by Tong Xing, Li-Juan Hu, Hong-Yan Zhao, Chen-Yuan Li, Zhen-Kun Wang, Meng-Zhu Shen, Zhong-Shi Lyu, Jing Wang, Yu Wang, Hao Jiang, Qian Jiang, Ying-Jun Chang, Xiao-Hui Zhang, Yuan Kong, Xiao-Jun Huang

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Implications of isolated MRD progression in newly diagnosed multiple myeloma treated with quadruplet therapy by Luciano J. Costa, Eva Medvedova, Binod Dhakal, Bhagirathbhai R. Dholaria, Kelly N. Godby, Susan Bal, Gayathri Ravi, Smith Giri, Saurabh Chhabra, Rebecca Silbermann, Natalie S. Callander

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A novel truncated fusion gene ETV6::AC010198.2 in post-MPN acute myeloid leukemia caused by del(12)(p13p11) by Jiao Lu, Jiao Lu, Guanqun Yang, Qiurong Zhang, Man Wang, Man Wang, Lijun Wang, Lijun Wang, Lu Chen, Haoyue Chen, Xin Jiang, Chunhua Liu, Tong Lin, Qiaoyan Han, Zefa Liu, Shi Zhen, Zhao Zeng, Jinlan Pan, Jiannong Cen, Suning Chen, Suning Chen, Zheng Wang, Zheng Wang, Xingxia Zhang, Miao Sun

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mTORC1-Activated Monocytes Increase Tregs and Inhibit the Immune Response to Bacterial Infections by Lijun Fang, Huaijun Tu, Wei Guo, Shixuan Wang, Ting Xue, Fei Yang, Xiaoyan Zhang, Yazhi Yang, Qian Wan, Zhexin Shi, Xulong Zhan, Jian Li

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Delayed neutrophil recovery following BCMA CAR-T therapy in Duffy-null myeloma does not impact severe infections or survival by Zachary M. Avigan, Saoirse Bodnar, Darren Pan, Jerrel Catlett, Joshua Richter, Larysa J. Sanchez, Cesar Rodriguez, Adriana C. Rossi, Shambavi Richard, Sundar Jagannath, Hearn Jay Cho, Samir Parekh, Santiago Thibaud

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Comparison of autologous hematopoietic cell transplantation, matched sibling donor hematopoietic cell transplantation, and chemotherapy in patients with favorable- and intermediate... by Mingyang Wang, Shulian Chen, Qiuqiu Zhang, Linyu Yuan, Xue Wang, Junshi Zhang, Xiaoyu Zhang, Yigeng Cao, Dongmei Li, Xinxiao Lu, Meijiao Wang, Xiaosi Jiang, Rongli Zhang, Xin Chen, Qiaoling Ma, Jialin Wei, Donglin Yang, Yi He, Aiming Pang, Sizhou Feng, Mingzhe Han, Weihua Zhai, Xingli Zhao, Erlie Jiang

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Long-term real-world evidence of CPX-351 of high-risk patients with AML identified high rate of negative MRD and prolonged OS by Thomas Cluzeau, Fabio Guolo, Edmond Chiche, Paola Minetto, Ramy Rahme, Sarah Bertoli, Luana Fianchi, Jean-Baptiste Micol, Michele Gottardi, Pierre Peterlin, Sara Galimberti, Xavier Thomas, Giuliana Rizzuto, Olivier Legrand, Michela Rondoni, Emmanuel Raffoux, Giambattista Bertani, Alexis Caulier, Michelina D’Argenio, Caroline Bonmati, Atto Billio, Caroline Lejeune, Barbara Scappini, Arnaud Pigneux, Patrizia Zappasodi, Christan Recher, Francesco Grimaldi, Lionel Ades, Roberto M. Lemoli

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Outcomes of follicular lymphoma with leukemic phase in the modern era: results from a large multicenter study by Asaad Trabolsi, Sunwoo Han, Narendranath Epperla, Kaitlin Annunzio, Firas Baidoun, Muhamad Alhaj Moustafa, Dan Morgenstern-Kaplan, Peter Doukas, Frederique St-Pierre, Brittany McCall, Lindsey Fitzgerald, Jose Sandoval-Sus, Shivani Dalal, Isildinha M. Reis, Jennifer Rose Chapman-Fredricks, Seo-Hyun Kim, Cherry Au, Natalie B. Otto, Khaled Alhamad, Thomas Ollila, Reem Karmali, Geoffrey Shouse, Izidore S. Lossos, Juan Pablo Alderuccio

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Serum B-cell maturation antigen could be a simple and accurate biomarker to identify and prognosticate monoclonal gammopathy of undetermined significance and smoldering multiple my... by Masanori Toho, Daisuke Ikeda, Shuichi Aikawa, Chiho Misono, Mitsuaki Oura, Fuminari Fujii, Hajime Sakuma, Atsushi Uehara, R ikako Tabata, Kentaro Narita, Masami Takeuchi, Tomohisa Watari, Yoshihito Otsuka, Kosei Matsue

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Granulocyte colony-stimulating factor in neutropenia management after CAR-T cell therapy: A safety and efficacy evaluation in refractory/relapsed B-cell acute lymphoblastic leukemi... by Xinping Cao, Meng Zhang, Ruiting Guo, Xiaomei Zhang, Rui Sun, Xia Xiao, Xue Bai, Cuicui Lyu, Yedi Pu, Juanxia Meng, Huan Zhang, Haibo Zhu, Pengjiang Liu, Zhao Wang, Yu Zhang, Wenyi Lu, Hairong Lyu, Mingfeng Zhao, Sihan Zhou, Xiuyuan Hao

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Analysis of early efficacy and immune reconstitution after autologous hematopoietic stem cell transplantation in multiple myeloma by Kaili Chen, Huixin Liang, Zezhong Yu, Guangyao Guo, Huijian Zheng, Yun Huang, Liping Liu, Jie Lin, Jinlan Long, Renyao Pan, Xi Chen, Changgui Wang, Wenjie Zhang, Zhenshu Xu

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An assessment model for efficacy of autologous CD19 chimeric antigen receptor T-cell therapy and relapse or refractory diffuse large B-cell lymphoma risk by Bin Xue, Yifan Liu, Min Zhang, Gangfeng Xiao, Xiu Luo, Lili Zhou, Shiguang Ye, Yan Lu, Wenbin Qian, Li Wang, Ping Li, Aibin Liang, Sihan Zhou, Xiuyuan Hao

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Targeting enolase 1 reverses bortezomib resistance in multiple myeloma through YWHAZ/Parkin axis by Xuejie Gao, Qilin Feng, Qikai Zhang, Yifei Zhang, Chaolu Hu, Li Zhang, Hui Zhang, Guanli Wang, Ke Hu, Mengmeng Ma, Zhuning Wang, Yujie Liu, Dong An, Hongfei Yi, Yu Peng, Xiaosong Wu, Gege Chen, Xinyan Jia, Haiyan Cai, Jumei Shi

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Optical genome mapping identified deletions, inversions, and insertions in hemophilia by Boyan Liu, Lu Zhou, Lijuan Cao, Haoning Liu, Laigen Tong, Zichan Zhang, Hongjie Shen, Changgeng Ruan, Yafeng Zhou, Miao Jiang

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Tyrosine kinase inhibitor discontinuation in non-allografted Philadelphia-positive acute lymphoblastic leukemia patients: a Campus ALL real-life study by Matteo Dragani, Michela Ansuinelli, Cristina Papayannidis, Nicola Fracchiolla, Valeria Cardinali, Michele Cedrone, Fabio Guolo, Salvatore Perrone, Prassede Salutari, Elisabetta Todisco, Robin Foà, Sabina Chiaretti

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Is CAR T a drug or a therapeutic pathway? Intention to treat versus per protocol analysis of real world studies of CAR-T cell therapy in relapsed refractory diffuse large B cell ly... by Rossana Di Staso, Beatrice Casadei, Frederick L. Locke, Michael Jain, Timothy J. Voorhees, Adam S. Kittai, Mariana Bastos-Oreiro, Antonio Gutiérrez, Alejandro Martin Garcia-Sancho, Maria Jose Terol, Monica Mead, Michael J. Maranzano, Gloria Iacoboni, Pere Barba, Mi Kwon, Rebeca Bailen, Juan Luis Reguera-Ortega, Agrima Mian, Brian Hill, Emmanuel Bachy, Franck Morschhauser, Roch Houot, Catherine Thieblemont, Steven Le Gouill, Riccardo Masetti, Davide Gori, Alessandro Broccoli, Pier Luigi Zinzani, Lisa Argnani

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Siltuximab for chimeric antigen receptor T-cell therapy–related CRS and ICANS: a multicenter retrospective analysis by Amneet Bajwa, Qiuhong Zhao, Marcus Geer, Chenyu Lin, James Westholder, Joseph Maakaron, Monalisa Ghosh, David Frame, Ahmed Galal, Justin Tossey, Nausheen Ahmed, Evandro Bezerra, Nathan Denlinger, Marcos de Lima, Narendranath Epperla, Paolo Caimi, Timothy Voorhees

“…Abstract: Chimeric antigen receptor T-cell (CAR-T) therapies are effective in many hematologic malignancies; however, adverse events including cytokine release syndrome (CRS) and immune effector cell–associated neurotoxicity syndrome (ICANS) can affect a significant number of patients. …”
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