Elritercept, a modified activin receptor IIA ligand trap, increased erythropoiesis and thrombopoiesis in a phase 1 trial by Jennifer Lachey, Christopher Rovaldi, Suresh Bobba, Jared Tur, Harveen Natarajan, Ben Snyder, Jasbir Seehra

“…The time course and duration of changes in these cell populations supported a differentiated pharmacologic profile that is consistent with the stimulation of both early- and late-stage hematologic pathways. The trial was registered at www.anzctr.org.au/ as #ACTRN12619000318189.…”
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Gambaran Perdarahan Intrakranial pada Perdarahan akibat Defisiensi Vitamin K (PDVK) di RSUP Dr. M. Djamil by Rizka Hanifa, Iskandar Syarif, Yusri Dianne Jurnalis

“…Kondisi mortalitas bayi dapat digambarkan dengan Angka Kematian Bayi (AKB) yang dapat disebabkan oleh kelainan hematologi seperti perdarahan intrakranial yang sering dihubungkan dengan defisiensi vitamin K dengan AKB sebesar 10-50%. …”
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Gambaran Klinis Penderita Penyakit Ginjal Kronik yang Menjalani Hemodialisis di RSUP Dr. M. Djamil Padang by Sitifa Aisara, Syaiful Azmi, Mefri Yanni

“…Uremia menyebabkan gangguan fungsi hampir semua sistem organ seperti; gangguan cairan dan elektrolit, metabolikendokrin, neuromuskular, kardiovaskular dan paru, kulit, gastrointestinal, hematologi serta imunologi. Hemodialisis merupakan suatu usaha untuk mengurangi gejala uremia tersebut, sehingga gambaran klinis pasien juga dapat membaik. …”
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Supplementation of Multistrain Probiotics Improves Milk Production, Blood Metabolites, Digestibility, and Rectal Microbiota during the Prepartum and Early Lactation Stages in Cross... by Mohamed S. Ayyat, Usama M. Abdel Monem, Gamal Abdel-Rahman, Adel Ibrahim Hussein, Hamdy A. El-Nagar, Wael M. Wafa, Samir Mahgoub, Adham A. Al-Sagheer

“…The MPF supplementation significantly enhanced feed conversion and significantly interacted with milk solids-not-fat, lactose, total solids, and protein. Hematological indicators did not significantly alter between the MPF and control groups. …”
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Monitoring Guidelines for Home and Outpatient Parenteral Antibiotic Therapy by Alain Y Martel

“…Other considerations for HIVAT include renal impairment, liver failure and hematological toxicities. These factors have led the author and colleagues to develop specific monitoring recommendations and techniques.…”
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Developing a machine learning model for predicting varicocelectomy outcomes: a pilot study by Coşkun Kaya, Mehmet Erhan Aydın, Özer Çelik, Aykut Aykaç, Mustafa Sungur

“…Demographic, anthropometric variables, physical examination findings, hematological, radiological, and semen analysis parameters were evaluated. …”
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Dengue Infection and Its Relationship with Evans Syndrome: A Pediatric Case by Ivan Jose Ardila Gomez, Pilar Pérez López, Mónika Rocío Hernández Carreño, Juan Camilo Barrios Torres

“…Here, we present the case of an unusual hematological and immunological complication of a patient who developed Evans syndrome during severe dengue, taking into account the concomitantly limited literature available for these two diseases, the need for a broader diagnostic approach, multidisciplinary intervention, and a more complex therapeutic approach.…”
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Epidemic situation on enzootic bovine leukosis in public and individual farms in the Republic of Dagestan by A. R. Mustafayev

“…In total, 524,930 animal sera samples were serologically tested using the immunodiffusion method, out of which 5,362 samples were seropositive in 2020. 1,265 sera samples from animals infected with the leukemia virus were tested using the hematological method, 251 animals (19.8%) with persistent leukocytosis were identified, which is the average for the past years. …”
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Effectiveness and Safety of Nonvitamin K Oral Anticoagulants Rivaroxaban and Apixaban in Patients with Venous Thromboembolism: A Meta-Analysis of Real-World Studies by Olivia Wu, Stephen Morris, Torben Bjerregaard Larsen, Flemming Skjøth, Alex Evans, Kevin Bowrin, Piotr Wojciechowski, Wojciech Margas, Maria Huelsebeck

“…Real-world evidence (RWE) studies were identified through a systematic literature review conducted between January 2012 and July 2020, using Embase, MEDLINE, and the websites of cardiological, hematological, and oncological associations. Eligible RWE studies recruited adult patients with deep vein thrombosis and/or pulmonary embolism and presented a comparison between rivaroxaban and apixaban versus SoC, consisting either of vitamin K antagonists, heparins, or combinations thereof. …”
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Exploring the efficacy of fluorouracil and platinum based chemotherapy in advanced hepatocellular carcinoma to bridge the treatment gap in resource limited settings by Se Jun Park, Kabsoo Shin, In-Ho Kim, MyungAh Lee, Tae Ho Hong, Hyunho Kim

“…A high pretreatment neutrophil-to-lymphocyte ratio (≥ 3.0) adversely affected both PFS (HR = 1.79; 95% CI, 0.99–3.25; p = 0.034) and OS (HR = 2.02; 95% CI, 1.10–3.69; p = 0.011). Hematologic toxicities related to the treatment were substantial, with 62.5% of patients experiencing grade 3 or 4 events, primarily neutropenia, which affected 60.4% of them. …”
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The Impact of COVID-19 on Clinical Outcomes in Patients With Traumatic Brain Injury by Farnaz Mahdavi, Sima Fallah-Arzpeima, Zoheir Reihanian, Khatereh Asadi, Nooshin Zaresharifi, Roghaye Zare, Mohammad Ali Yazdanipour, Masoud Shabani Chobe

“…COVID-19 can impact the central nervous system (CNS) and hematologic system and appears to affect clinical outcomes and the average cerebral hemorrhage volume (ACHV) in patients with TBI. …”
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Methanolic Extract of Distemonanthus benthamianus (Caesalpiniaceae) Stem Bark Suppresses Ethanol/Indomethacin-Induced Chronic Gastric Injury in Rats by Vanessa Mba Matah Marte, Gilbert Ateufack, Marius Mbiantcha, Albert Donatien Atsamo, Carine Flore Adjouzem, Stéphanie Flore Djuichou Nguemnang, Eric Gonzal Tsafack, William Yousseu Nana, Yacine Karelle Madjo Kouam, Elvira Ngoufack Azanze

“…In addition, the extract significantly decreases the level of MDA, significantly increases the activities of catalase and glutathione, and then improves the hematological parameters in sick animals. Histological micrographs show that in the presence of the extract, there is advanced reepithelialization with recovery of the ulcerated epithelium. …”
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The Association between Antiphospholipid and Coagulation in Pregnant Women with Blood Clotting by Dabah Dakil Awad, Iktefa Abdul Hameed Mohammed Saeed, Maha El. Jasim

“…Background: Antiphospholipid syndrome is a systemic hematological autoimmune disease characterized by a hypercoagulable state, which is associated with vascular thrombosis and/or obstetric morbidity characterized by miscarriage, fetal death, and/or premature birth. …”
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Dysregulated T Cell Activation and Aberrant Cytokine Expression Profile in Systemic Lupus Erythematosus by Haiyan Zhou, Bojiang Li, Jing Li, Tongqian Wu, Xiaoqian Jin, Rui Yuan, Ping Shi, Yan Zhou, Long Li, Fang Yu

“…In addition, patients with hematologic manifestations displayed elevated frequencies of HLA-DR+ T cells and ICOS+ T cells. …”
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Investigation of CD47 Expression in Renal Cell Tumors and Evaluation of Its Relationship with Prognostic Parameters by Ömer Faruk Dizibüyük, Zehra Bozdağ, Metin Karakök

“…Much progress has been made in targeting CD47 for cancer immunotherapy in solid tumors (STs) and hematological malignancies. This study aimed to evaluate CD47 expression in malignant and benign renal cell tumors and compare it with prognostic histopathological parameters. …”
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Donor Parameters and Platelet Yield during Plateletpheresis: A Cross-sectional Prospective Study by Ruchi Singh, Ganga S. Pilli, Ramadevi Vivek Wani

“…The demographic and hematologic parameters of donors were correlated with their platelet yield. …”
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Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin-Induced Cardiotoxicity in Rats by Olufunke Esan Olorundare, Adejuwon Adewale Adeneye, Akinyele Olubiyi Akinsola, Daniel Ayodele Sanni, Mamoru Koketsu, Hasan Mukhtar

“…Doxorubicin is widely applied in hematological and solid tumor treatment but limited by its off-target cardiotoxicity. …”
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The effects of fluid resuscitation on the hemodynamic parameters of experimental induced endotoxemia in the neonatal calves by Enes Akyüz, Alparslan Coşkun, İsmail Şen

“…The primary aim of the study is to determine the effects of NaCl on the clinic, hematologic and hemodynamic parameters of calves.</p> <p><strong>Materials and Methods:</strong> Twelve healthy calves, aged between 5 to 15 days included into the study. …”
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Safety and effectiveness of an herbal decoction (modified Saengmaeksan) in hypertensive patients: Protocol for a real-world prospective observational study. by Nahyun Cho, Hobin Moon, Kyung-Min Shin, Byoung-Kab Kang, Jungtae Leem, Changsop Yang

“…Safety assessments will include monitoring hematologic parameters and adverse events. Data will be analyzed using an ANCOVA model for adjusting confounders.…”
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Sodium valproate enhances efficacy of NKG2D CAR-T cells against glioblastoma by Junchen Liu, Junchen Liu, Kun Dai, Kun Dai, Muhammad Auwal Saliu, Muhammad Auwal Saliu, Mansur Dabai Salisu, Mansur Dabai Salisu, Jiangyu Gan, Lukman Olalekan Afolabi, Dehong Yan, Guizhong Zhang, Maoxuan Liu, Maoxuan Liu, Xiaochun Wan, Xiaochun Wan

“…NKG2D CAR-T cells have demonstrated a favorable safety profile in patients with hematologic tumors, and showed robust antitumor efficacy in various xenograft models, including glioblastoma. …”
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