Advancing Multiple Myeloma Immunotherapy: A Review of Chimeric Antigen Receptor T-Cell and Bispecific T-Cell Engagers Cell Therapies in Revolutionizing Treatment by Rahul Navab, Pragyat Futela, Verkha Kumari, Jayesh Valecha, Ramansh Bandhu Gupta, Rohit Jain

“…Multiple Myeloma (MM) is a hematologic malignancy characterized by clonal plasma cell development, leading to serious complications. …”
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The Dual Role of HLA-G in Cancer by Nathalie Rouas-Freiss, Philippe Moreau, Joel LeMaoult, Edgardo D. Carosella

“…We here review the current data on the role of HLA-G in cancer based on recent findings of an unexpected antitumor activity of HLA-G in hematological malignancies. For the past decade, HLA-G has been described as a tumor-escape mechanism favoring cancer progression, and blocking strategies have been proposed to counteract it. …”
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An Approach to Iron-Deficiency Anemia by Imran Rasul, Gabor P Kandel

“…The present article provides a broad overview of iron-deficiency anemia, with particular emphasis on hematological diagnosis, etiology, the use of endoscopy in identifying lesions and iron-repletion therapy. …”
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Hypercalcemia, Anemia, and Acute Kidney Injury: A Rare Presentation of Sarcoidosis by Neeraj Sharma, Hassan Tariq, Kalpana Uday, Yevgeniy Skaradinskiy, Masooma Niazi, Sridhar Chilimuri

“…Our Initial impression was likely underlying hematologic malignancy such as lymphoma or multiple myeloma. …”
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Exosomal lncRNAs as diagnostic and therapeutic targets in multiple myeloma by Hong Yan, Nan Jiang, Xiaoying Li, Chenyang Lin, Fang Wang, Juan Zhang, Lijuan Chen, Dan Li

“…Multiple Myeloma (MM) is the second most common malignancy of the hematopoietic system, accounting for approximately 10% of all hematological malignancies, and currently, there is no complete cure. …”
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Antiphospholipid Syndrome as a Cause of Recurrent Portal Vein Thrombosis in a Man with a Medical History of other Thrombosis by R. G. Sayfutdinov, R. R. Saifutdinov, R. R. Akhunova, T. V. Saifutdinova, G. R. Absalyamova, T. V. Dvoryankina, G. R. Akhunova

“…APS is a syndrome that includes venous and/or arterial thrombosis, various forms of obstetric pathology, thrombocytopenia, as well as a variety of neurological, skin, cardiovascular and hematological disorders. The article presents a clinical case of a male patient with several episodes of vascular thrombosis, two of which (thrombophlebitis of the veins of the lower extremities and stroke) developed at the age of 39 years, and recurrent thrombosis of the portal vein since 2018. …”
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Current Advances in Red Blood Cell Generation Using Stem Cells from Diverse Sources by Yoojin Seo, Kyung-Hwa Shin, Hyung Hoi Kim, Hyung-Sik Kim

“…Moreover, individuals with severe hematological abnormalities or rare blood phenotypes need alternative therapeutic approaches instead of conventional blood transfusion. …”
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Embolic Stroke due to a Common Carotid Artery Thrombus in a Young Patient with Severe Iron-Deficiency Anemia without Thrombocytosis by David Roshal

“…This case report suggests that severe iron-deficiency anemia with or without reactive thrombocytosis should be viewed as a possible hematologic condition associated with thrombotic tendencies and a risk factor for ischemic stroke, especially in young adults. …”
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Serological diagnosis of toxoplasmosis and determination of seroprevalence of anti-toxoplasma gondii antibodies in cattle in bursa province by Engin Kennerman, Güney Kaya, Serkal Gazyağcı, Cahit Babur, Selçuk Kılıç

“…No difference was detected in hematological analysis of seropositive and seronegative cattle. …”
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Disseminated Intravascular Coagulation and Malignancy: A Case Report and Literature Review by Sumit Sohal, Akhilesh Thakur, Aleena Zia, Mina Sous, Daniela Trelles

“…Disseminated Intravascular Coagulation (DIC) is a disorder of coagulation which is commonly seen as a complication of infections, traumas, obstetric diseases, and cancers especially hematological and rarely solid cancers. DIC may rarely be the presenting feature of an undiagnosed malignancy. …”
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Successful Treatment of Severe Type B Lactic Acidosis in a Patient with HIV/AIDS-Associated High-Grade NHL by Marco Mejia, Ariel Perez, Harold Watson, Daniel Sanchez, Jorge Parellada, Mario Madruga, S. J. Carlan

“…Type B lactic acidosis is a rare metabolic complication sometimes associated with hematologic malignancies. When present, this type of lactic acidosis is most commonly seen in patients with high-grade lymphomas or leukemias and is usually indicative of a dismal prognosis. …”
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AM3, an Oral BRM: Protective Agent against Iatrogenic Bone-Marrow and Liver Damage in Breast Cancer Patients under Conventional Adjuvant Radiochemotherapy by Vicente G Villarrubia, Paula Marquez, Jose Cobo, Guillermo J Sada

“…The incidence of thrombocytopenia in patients receiving combined radio-chemotherapy only was 70% compared with 6% observed in patients also receiving AM3 treatment. Besides these hematological effects, AM3 palliated subclinical hepatic toxicity due to combined radio-chemotherapy. …”
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A Review of Routine Laboratory Biomarkers for the Detection of Severe COVID-19 Disease by Keynaz Keykavousi, Fahimeh Nourbakhsh, Nooshin Abdollahpour, Farzaneh Fazeli, Alireza Sedaghat, Vahid Soheili, Amirhossein Sahebkar

“…The purpose of this review is to investigate the role of hematological (white blood cell (WBC), lymphocyte, and neutrophil count, neutrophil-to-lymphocyte ratio (NLR), platelet, and red blood cell (RBC) count), inflammatory (C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and lactate dehydrogenase (LDH)), and biochemical (Albumin, aspartate aminotransferase (AST) and alanine aminotransferase (ALT), blood urea nitrogen (BUN), creatinine, D-dimer, total Cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL)) biomarkers in the pathogenesis of COVID-19 disease and how their levels vary according to disease severity.…”
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Clinical Features and Outcome of Mucormycosis by Carlos Rodrigo Camara-Lemarroy, Emmanuel Irineo González-Moreno, René Rodríguez-Gutiérrez, Erick Joel Rendón-Ramírez, Ana Sofía Ayala-Cortés, Martha Lizeth Fraga-Hernández, Laura García-Labastida, Dionicio Ángel Galarza-Delgado

“…Ten patients had diabetes mellitus as the underlying disease, and 6 patients had a hematological malignancy (acute leukemia). Of the diabetic patients, 3 had chronic renal failure and 4 presented with diabetic ketoacidosis. …”
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Current and Future Perspectives of PD-1/PDL-1 Blockade in Cancer Immunotherapy by Rangarirai Makuku, Neda Khalili, Sepideh Razi, Mahsa Keshavarz-Fathi, Nima Rezaei

“…Immune checkpoint blockade through targeting programmed cell death protein-1 (PD-1) has demonstrated promising antitumor effects in cancer immunotherapy of many different solid and hematologic malignancies. However, despite promising results, a favorable response is observed only in a fraction of patients, and there is still lack of a single therapy modality with curative ability. …”
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Disseminated nocardiosis in a patient with AIDS and B-cell non-Hodgkin’s lymphoma: a case report by Delvis R. Reverón, David M. Flora-Noda, Lily M. Soto, Maribel Dolande, Juan Frey, Aleiram Chaurio, Bárbara D. Ruiz-Alayón, Jocays Caldera, Fhabián S. Carrión-Nessi, David A. Forero-Peña

“…Abstract Background Disseminated nocardiosis is a rare and potentially fatal disease, with a higher incidence in immunocompromised patients, such as those living with human immunodeficiency virus (HIV) or hematological malignancies, including lymphoma. Information on Nocardia spp. infection in Venezuela is limited. …”
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In Vitro 3D Models of Haematological Malignancies: Current Trends and the Road Ahead? by Carlotta Mattioda, Claudia Voena, Gianluca Ciardelli, Clara Mattu

“…This review aims at reporting an updated overview of state-of-the-art hematological malignancies 3D in vitro models, emphasizing the key features and limitations of existing systems to inspire further research in this underexplored field.…”
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Expression profiles of miR-101-3p and miR-431-5p as potential diagnostic biomarkers for rheumatoid arthritis by Mohamed M. Sadaty, Salma M. Mekhemer, Shaimaa Abdel-Ghany, Amira R. El-Ansary, Rana Mohamed, Nashaat N. Kamal, Hussein Sabit

“…Comprehensive analysis of patient data, encompassing serological, hematological, and biochemical markers, revealed significantly elevated levels of miR-99b-5p, miR-101-3p, and miR-431-5p in RA patients compared to healthy controls. …”
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Donor lymphocyte infusions: An experience from a tertiary care center of North India by Divjot Singh Lamba, Parmatma Prasad Tripathi, Rekha Hans, Alka Khadwal, Ratti Ram Sharma

“…However, further evidence is required to evaluate its efficacy, especially in relapsed or residual hematological malignancies.…”
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Translating Unconventional T Cells and Their Roles in Leukemia Antitumor Immunity by Nilberto Dias de Araújo, Fábio Magalhães Gama, Mateus de Souza Barros, Thaís Lohana Pereira Ribeiro, Fabíola Silva Alves, Lilyane Amorim Xabregas, Andréa Monteiro Tarragô, Adriana Malheiro, Allyson Guimarães Costa

“…In recent years, these cell populations have been associated with a repertoire of anti- or protumor responses and play important roles in the dynamics of solid tumors and hematological malignancies, thus, encouraging the development of new investigations in the area. …”
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