Herpesvirus Infections After Chimeric Antigen Receptor T-Cell Therapy and Bispecific Antibodies: A Review by Joseph Sassine, Emily A. Siegrist, Roy F. Chemaly

“…In this narrative review, we explore the burden and risk factors of various herpesvirus infections in patients receiving chimeric antigen receptor T-cell (CAR-T) therapy or bispecific antibodies (BsAb) for the treatment of hematologic malignancies. Antiviral prophylaxis for herpes simplex/varicella zoster viruses became part of the standard of care in this patient population. …”
Get full text

Persistence of Brucella abortus in the Bone Marrow of Infected Mice by Cristina Gutiérrez-Jiménez, Lisiena Hysenaj, Alejandro Alfaro-Alarcón, Ricardo Mora-Cartín, Vilma Arce-Gorvel, Edgardo Moreno, Jean Pierre Gorvel, Elías Barquero-Calvo

“…Persistence of Brucella in the BM has been associated with hematological complications such as neutropenia, thrombocytopenia, anemia, and pancytopenia in human patients. …”
Get full text

Severe Hemolytic Anemia Associated with Mild Pneumonia Caused by Mycoplasma pneumonia by Zafer Kurugol, Serife Sebnem Onen, Guldane Koturoglu

“…As the erythrocyte sedimentation rate was excessively elevated, the differential diagnosis primarily comprised hematological malignancies. Direct Coombs' test was positive. …”
Get full text

Lymphomatoid granulomatosis. Case Presentation by Marisela García de la Torre, Yanelka Bouza Jiménez, Stephany Milagros Acosta País, Maribel Misa Menéndez

“…He started with a maintained fever of 38 0C, malaise, weight loss, hepatomegaly and small non-painful adenopathies in the inguinal and axillary regions, so he was admitted on January 14, 2018 at the Gustavo Aldereguía Lima Hospital in Cienfuegos and was treated with antibiotic before a hematological profile which indicated associated sepsis. …”
Get full text

Transplant Tolerance: New Insights and Strategies for Long-Term Allograft Acceptance by Paulina Ruiz, Paula Maldonado, Yessia Hidalgo, Alejandra Gleisner, Daniela Sauma, Cinthia Silva, Juan Jose Saez, Sarah Nuñez, Mario Rosemblatt, Maria Rosa Bono

“…Today, organ transplantation between genetically dissimilar individuals (allogeneic grafting) is a procedure widely used as a therapeutic alternative in cases of organ failure, hematological disease treatment, and some malignancies. …”
Get full text

Case Report: Staged surgical management in ESRD: off-pump CABG followed by renal transplantation to enhance graft survival by Özge Çetinarslan, Davit Saba

“…The main advantage of OPCAB surgery compared to on-pump CABG (ONCAB) is that it requires fewer blood product transfusions and has fewer renal, pulmonary, and hematological complications. This case series uniquely discusses two patients who underwent successful beating heart CABG without blood transfusion, followed by RT.…”
Get full text

Serum Copper and Haematological Values of Sheep of Different Physiological Stages in the Dry and Wet Seasons of Central Trinidad by A. Mohammed, M. Campbell, F. G. Youssef

“…A study was conducted to determine serum copper (Cu) concentrations and hematological values of 174 sheep from four medium sized farms, pertaining to physiological stage, in the late dry and late wet seasons of Central Trinidad. …”
Get full text

Recurrent Diffuse Large B-Cell Lymphoma with the Initial Manifestation of Retinal Involvement by Wan-Ting Yeh, Jen-Tsun Lin*

“…Diffuse large B-cell lymphoma (DLBL) is a common hematological disorder that frequently presents with fever and lymphadenopathy initially. …”
Get full text

NK Cell and CD4+FoxP3+ Regulatory T Cell Based Therapies for Hematopoietic Stem Cell Engraftment by Antonio Pierini, Maite Alvarez, Robert S. Negrin

“…Allogeneic hematopoietic cell transplantation (HCT) is a powerful therapy to treat multiple hematological diseases. The intensive conditioning regimens used to allow for donor hematopoietic stem cell (HSC) engraftment are often associated with severe toxicity, delayed immune reconstitution, life-threatening infections, and thus higher relapse rates. …”
Get full text

A pivotal decade for bispecific antibodies? by Marlena Surowka, Christian Klein

“…In the 2020s, the approval of additional bsAbs can be expected in hematological malignancies, solid tumors and non-oncology indications, establishing bsAbs as essential part of the therapeutic armamentarium.…”
Get full text

Determinants of Anemia among HIV-Positive Children on Highly Active Antiretroviral Therapy Attending Hospitals of North Wollo Zone, Amhara Region, Ethiopia, 2019: A Case-Control St... by Biruk Beletew, Ayelign Mengesha, Mohammed Ahmed, Awet Fitwi, Mesfin Wudu

“…Anemia is one of the most commonly observed hematological abnormalities and an independent poor prognostic marker of HIV disease. …”
Get full text

Parasitological and clinical correlates of Plasmodium–Schistosoma mansoni co-infection and its determinants among Plasmodium-infected patients in the Wolaita Zone, South Ethiopia r... by Kemal Mohamed, Tariku Belay, Ahmed Zeynudin

“…Co-infection results in the change of Plasmodium density, hematological, and biochemical parameters in malaria patients.…”
Get full text

The AST/ALT (De Ritis) ratio as a significant prognostic factor in myelodysplastic syndrome by Ying Chen, Yue Wu, Ting Chen, Duobing Zou, Cong Shi, Ningning Wu, Lixia Sheng, Guifang Ouyang, Qitian Mu

Get full text

Advancing Multiple Myeloma Immunotherapy: A Review of Chimeric Antigen Receptor T-Cell and Bispecific T-Cell Engagers Cell Therapies in Revolutionizing Treatment by Rahul Navab, Pragyat Futela, Verkha Kumari, Jayesh Valecha, Ramansh Bandhu Gupta, Rohit Jain

“…Multiple Myeloma (MM) is a hematologic malignancy characterized by clonal plasma cell development, leading to serious complications. …”
Get full text

The Dual Role of HLA-G in Cancer by Nathalie Rouas-Freiss, Philippe Moreau, Joel LeMaoult, Edgardo D. Carosella

“…We here review the current data on the role of HLA-G in cancer based on recent findings of an unexpected antitumor activity of HLA-G in hematological malignancies. For the past decade, HLA-G has been described as a tumor-escape mechanism favoring cancer progression, and blocking strategies have been proposed to counteract it. …”
Get full text

An Approach to Iron-Deficiency Anemia by Imran Rasul, Gabor P Kandel

“…The present article provides a broad overview of iron-deficiency anemia, with particular emphasis on hematological diagnosis, etiology, the use of endoscopy in identifying lesions and iron-repletion therapy. …”
Get full text

Hypercalcemia, Anemia, and Acute Kidney Injury: A Rare Presentation of Sarcoidosis by Neeraj Sharma, Hassan Tariq, Kalpana Uday, Yevgeniy Skaradinskiy, Masooma Niazi, Sridhar Chilimuri

“…Our Initial impression was likely underlying hematologic malignancy such as lymphoma or multiple myeloma. …”
Get full text

Antiphospholipid Syndrome as a Cause of Recurrent Portal Vein Thrombosis in a Man with a Medical History of other Thrombosis by R. G. Sayfutdinov, R. R. Saifutdinov, R. R. Akhunova, T. V. Saifutdinova, G. R. Absalyamova, T. V. Dvoryankina, G. R. Akhunova

“…APS is a syndrome that includes venous and/or arterial thrombosis, various forms of obstetric pathology, thrombocytopenia, as well as a variety of neurological, skin, cardiovascular and hematological disorders. The article presents a clinical case of a male patient with several episodes of vascular thrombosis, two of which (thrombophlebitis of the veins of the lower extremities and stroke) developed at the age of 39 years, and recurrent thrombosis of the portal vein since 2018. …”
Get full text

Current Advances in Red Blood Cell Generation Using Stem Cells from Diverse Sources by Yoojin Seo, Kyung-Hwa Shin, Hyung Hoi Kim, Hyung-Sik Kim

“…Moreover, individuals with severe hematological abnormalities or rare blood phenotypes need alternative therapeutic approaches instead of conventional blood transfusion. …”
Get full text

Embolic Stroke due to a Common Carotid Artery Thrombus in a Young Patient with Severe Iron-Deficiency Anemia without Thrombocytosis by David Roshal

“…This case report suggests that severe iron-deficiency anemia with or without reactive thrombocytosis should be viewed as a possible hematologic condition associated with thrombotic tendencies and a risk factor for ischemic stroke, especially in young adults. …”
Get full text