Influencing factors of acute kidney injury in elderly patients with diabetic nephropathy and establishment of nomogram model by Ganlin Wu, Ganlin Wu, Yanli Ye, Meirong Xu, Yanxia Zhang, Zuopeng Lu, Lv Huang

“…The prevalence and predisposing factors of acute kidney injury in diabetic nephropathy were analyzed, multivariate logistic regression were used to analyze the influencing factors of acute kidney injury in patients, and a nomogram risk prediction model was established based on risk factors for verification.ResultsAnalysis of the factors of acute kidney injury in diabetic nephropathy found that severe infection was the main trigger, accounting for 40.00%, followed by nephrotoxic antibiotics and severe heart failure. The age, urine microalbumin-to-creatinine ratio (ACR), blood urea nitrogen (BUN), uric acid(UA), and cystatin C (CysC) levels of patients in the combined acute kidney injury group were significantly higher than those in the unmerge group (P<0.05), and the left ventricular ejection fraction (LVEF) and epidermal growth factor receptor (eGFR) levels were significantly lower than those in the unmerge group (P<0.05). …”
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Clarithromycin-Associated Acute Liver Failure Leading to Fatal, Massive Upper Gastrointestinal Hemorrhage from Profound Coagulopathy: Case Report and Systematic Literature Review by Ahmed I. Edhi, Seifeldin Hakim, Christienne Shams, Damanpreet Bedi, Mitual Amin, Mitchell S. Cappell

“…The six previously reported cases were limited by failure to exclude hepatitis E (4), lack of liver biopsy (2), and uninterpretable liver biopsy (1) and by confounding potential etiologies including disulfiram, israpidine, or recent acetaminophen use (3), clarithromycin overdose (1), active alcohol use (1), and severe heart failure (1). Review of 6 previously reported and current case of clarithromycin-associated ALF revealed that patients had AST and ALT values in the thousands. …”
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Medication patterns and potentially inappropriate medication in patients with metastatic breast cancer: results of the BRE-BY-MED study by Lilly Sophia Brandstetter, Anna Grau, Peter U. Heuschmann, Max Müller-Reiter, Jessica Salmen, Stefan Störk, Achim Wöckel, Jens-Peter Reese

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Prognostic Value of the Tricuspid Regurgitation Impact on Outcomes (TRIO) Score in Patients Undergoing Transcatheter Aortic Valve Implantation by Jizhong Wang, Yuanwei Chen, Xuxing Zhang, Songyuan Luo, Jie Li, Fang Pei, Jianfang Luo

“…The primary outcome was all-cause mortality, while secondary outcomes included complications defined by the Valve Academic Research Consortium 2 (VARC-2) criteria and major adverse cardiovascular events (MACEs), including mortality, stroke, and heart failure rehospitalization. …”
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The design and rationale of the cardiac REHABilitation to improve metabolic health in Hypertrophic CardioMyopathy (REHAB-HCM) Study by Matthew Cheung, Nathaniel Moulson, Jinelle C. Gelinas, Ali Daraei, Sarah M. Bradwell, Carolyn Taylor, Neil D. Eves, Graeme J. Koelwyn, Thomas M. Roston

“…Cardiac rehabilitation (CR) has been shown to improve metabolic parameters in populations with heart failure and myocardial infarction. However, there is a paucity of data on the impact of CR in the HCM population with metabolic syndrome. …”
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Primary Terminal Haemochromatosis in a 50 Year-Old Patient by M. I. Gonik, M. S. Zharkova, O. Yu. Kiseleva, E. V. Berezina, Sh. A. Ondos, Yu. V. Lerner, E. A. Kogan, V. T. Ivashkin

“…Further examination aimed at excluding occult gastrointestinal bleeding, adrenal insufficiency, decompensated heart failure. Bronze skin and icteric sclerae were positive. …”
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CytoSorb hemoadsorption of apixaban during cardio-pulmonary bypass for heart transplantation by Anouk Frering, MD, Antoine Abi Lutfallah, MD, Aude Carillion, MD, PhD, Daniel Wendt, MD, Pascal Leprince, MD, PhD, Adrien Bougle, MD, PhD, Guillaume Lebreton, MD, PhD

“…This patient, has an end-stage heart failure with multiple episodes of decompensation over the previous year. …”
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Repeated heart rate variability monitoring after myocardial infraction – Cohort profile of the MI-ECG study by Teemu Pukkila, Jani Rankinen, Leo-Pekka Lyytikäinen, Niku Oksala, Kjell Nikus, Esa Räsänen, Jussi Hernesniemi

“…Our findings show that HRV parameters remained stable during the initial weeks post-MI, indicating that the timing of Holter monitoring in this period is not critical.Several HRV parameters were significantly correlated with MI type, Killip class, and left ventricular ejection fraction (LVEF), with reduced HRV observed in STEMI patients and those with decompensated heart failure. However, after adjusting for GRACE score and LVEF, the prognostic value of most HRV measures for predicting future cardiac events diminished. …”
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Penggunaan Obat Antihipertensi pada Pasien Hipertensi Esensial di Poliklinik Ginjal Hipertensi RSUP DR. M. Djamil Tahun 2011 by Heri Fitrianto, Syaiful Azmi, Husnil Kadri

“…Compositions of 103 hypertension patients with complience indications are 63 patients with diabetes mellitus, 13 patients with PJK, 13 patients with stroke, 7 patients with heart failure, 4 patients with post-infarct myocardium, and 3 patients with chronic kidney failure. …”
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Association between weight-adjusted-waist index and long-term prognostic outcomes in cardiovascular disease patients: results from the NHANES 1999–2018 study by Hanbin Li, Wen Zhong, Hongxin Cheng, Shiqi Wang, Ran Li, Lu Wang, Chengqi He, Quan Wei

“…The risk of all-cause mortality increased with WWI and showed a linear association in patients with congestive heart failure, heart attack (P-overall < 0.05, P − nonlinear > 0.05); WWI was nonlinearly associated with the risk of all-cause mortality in patients with coronary heart disease and angina (P-overall < 0.05, P − nonlinear < 0.05). …”
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Ten Machine Learning Models for Predicting Preoperative and Postoperative Coagulopathy in Patients With Trauma: Multicenter Cohort Study by Xiaojuan Xiong, Hong Fu, Bo Xu, Wang Wei, Mi Zhou, Peng Hu, Yunqin Ren, Qingxiang Mao

“…Multivariate logistic regression revealed that patients with PPTIC faced significantly higher risks of sepsis (1.75-fold), heart failure (1.5-fold), delirium (3.08-fold), abnormal coagulation (3.57-fold), tracheostomy (2.76-fold), mortality (2.19-fold), and urinary tract infection (1.95-fold), along with longer hospital and intensive care unit stays. …”
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Physiologists as medical scientists: An early warning from the German academic system by Katrin Streckfuss‐Bömeke, Nicolle Kränkel, Christoph Maack, Renate B. Schnabel, Laura C. Zelarayán, Norbert Frey, Peter Jezzard, Martina Krüger, Nico Lachmann, Susanne Lutz, Claudia Noack, Eric Schoger, Katrin Schröder, Laura C. Sommerfeld, Sabine Steffens, Holger Winkels, Christina Würtz, Tanja Zeller, Eva A. Rog‐Zielinska, Peter Kohl

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Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional Study by Shalom Sabwa, Vanessa Rouzier, Rodney Sufra, Reichling St. Sauveur, Nour Mourra, Rehana Rasul, Joseph Inddy, Lily D. Yan, Madeline Sterling, Laura Pinheiro, Marie Deschamps, Jean William Pape, Margaret L. McNairy

“…Adjusted models revealed CVD multimorbidity was inversely related to physical component summary (−2.7 [95% CI, −3.8 to −1.6]) and mental component summary (−1.0 [95% CI, −1.8 to −0.2]). Heart failure and hypertension showed the strongest CVD morbidities associated with poor HRQOL. …”
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Asymptomatic Post-Traumatic Rupture of the Right Diaphragm Dome by E. A. Losik, M. V. Fadeeva, V. V. Shchegelsky, R. T. Rzaev, A. V. Stepanov, K. B. Puzakov, M. R. Skhirtladze

“…A 61-year-old man was admitted to hospital with a diagnosis of chronic heart failure. Chest radiograph revealed a high position of the right dome of the diaphragm. …”
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Computational pathology assessments of cardiac stromal remodeling: Clinical correlates and prognostic implications in heart transplantation by Eliot G. Peyster, MD, MSc, Cai Yuan, PhD, Sara Arabyarmohammadi, PhD, Priti Lal, MD, Michael D. Feldman, MD, PhD, Pingfu Fu, PhD, Kenneth B. Margulies, MD, MS, Anant Madabhushi, PhD, FAIMBE, FIEEE, FNAI

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Corticosteroid use beyond 1-year post heart transplantation is associated with worse outcomes: A contemporary analysis of the ISHLT registry by Abhishek Jaiswal, MD, William L. Baker, Pharm.D, Ashwin Pillai, MD, Michelle Kittleson, MD, PhD, Balaphanidhar Mogga, MD, Zeina Jedeon, MD, Caroline Chen, David A. Baran, MD

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Association of Time in Target Range of Resting Heart Rate With Adverse Clinical Outcomes in Patients With Acute Coronary Syndromes After Percutaneous Coronary Intervention by Jianmei Zheng, Cen Chen, Zhongcai Fan, Qiang Ye, Yi Zhong, Jinsong Li, Hao Huang, Jianping Deng, Jinghong Zhao, Tinglin Xiong, Wenjie Tian, Xuemei Zhang

“…Compared to patients with TTR-HR 0–50% and >50%–75%, patients with TTR-HR > 75%–100% were older and less alcohol user, less likely to use diuretics and anti-diabetic drugs, these patients had less comorbidities of hyperlipidemia, diabetes, heart failure, and cardiac shock. After 12 months follow up, the incidence of MACE and composite endpoint but not mortality was higher in patients with TTR-HR 0–50% and >50%–75% than those with TTR-HR > 75%–100%. …”
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Impact of a nurse-led teleconsultation strategy for cardiovascular disease management during COVID-19 pandemic in India: a pyramid model feasibility study by Dorairaj Prabhakaran, Kavita Singh, Ambuj Roy, Bishav Mohan, Rohit Tandon, Abhishek Goyal, Bhupinder Singh, Shibba Takkar Chhabra, Naved Aslam, Gurpreet Singh Wander, Nitish Naik, Gurbhej SIngh, Shivaansh Aggarwal, Aftabh Saini

“…During stage 1 nurse-led teleconsultations, patients were referred to the physicians due to uncontrolled diabetes (24.9%), uncontrolled hypertension (18.7%) and congestive heart failure (16.2%). The patient’s treatment satisfaction was similar between the nurse-led versus physician-led teleconsultations (p=0.07).Conclusion This study showed that a nurse-led telemedicine strategy is feasible to implement in a resource-constraint setting for triaging patients with CVD and reduces physician’s burden.…”
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The Relationship of Conduction Disorder and Prognosis in Patients with Acute Coronary Syndrome by Wei-Chieh Lee, Yen-Nan Fang, Tien-Yu Chen, Yun-Yu Hsieh, Yi-Hsuan Tsai, Hsiu-Yu Fang, Po-Jui Wu, Huang-Chung Chen, Ping-Yen Liu

“…The following clinical outcomes were compared between patients with and without conduction disorders: heart failure (HF) hospitalization, cardiovascular (CV) mortality, and all-cause mortality. …”
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Risk factors for thromboembolic and bleeding events in anticoagulated patients with atrial fibrillation: the prospective, multicentre observational PREvention oF thromboembolic eve... by Raffaele De Caterina, Kurt Huber, Richard Schilling, Miklos Rohla, Thomas W Weiss, Ladislav Pecen, Giuseppe Patti, Jolanta M Siller-Matula, Renate B Schnabel, Dipak Kotecha, Markus Lucerna, Paulus Kirchhof

“…The incidence of thromboembolic and major bleeding events was 2.34% (95% CI 1.93% to 2.74%) and 2.84% (95% CI 2.41% to 3.33%) after 1-year of follow-up, respectively.Abnormal liver function, prior stroke or transient ischaemic attack, labile international normalised ratio (INR), concomitant therapy with antiplatelet or non-steroidal anti-inflammatory drugs, heart failure and older age (≥75 years) were independently associated with both thromboembolic and major bleeding events.With the exception of unstable INR values, these risk factors were validated in patients treated with NOACs (PREFER in AF Prolongation Study, 72±9 years, 40% female, CHA2DS2-VASc 3.3±1.6). …”
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