The relationship between walking speed and changes in cardiovascular risk factors during a 12-day walking tour to Santiago de Compostela: a cohort study by Frank L J Visseren, Yolanda van der Graaf, Wilko Spiering, Remy H H Bemelmans, Paulus P Blommaert, Annemarie M J Wassink, Blai Coll

“…A 1 km/h higher walking speed was related to an increase in HDL-c (0.24; 95% CI 0.12 to 0.30 mmol/l), LDL-c (0.18; 95% CI −0.16 to 0.42 mmol/l) and total cholesterol (0.36; 95% CI 0.12 to 0.60 mmol/l), adjusted for age, gender, smoking, body mass index and heart rate, during the whole walking tour.Conclusions Walking the same distance faster improves HDL-c more, while LDL-c and total cholesterol decrease more with lower walking speed independent of changes in body weight in healthy middle-aged subjects.…”
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Prognostic Value of the Tricuspid Regurgitation Impact on Outcomes (TRIO) Score in Patients Undergoing Transcatheter Aortic Valve Implantation by Jizhong Wang, Yuanwei Chen, Xuxing Zhang, Songyuan Luo, Jie Li, Fang Pei, Jianfang Luo

“…The primary outcome was all-cause mortality, while secondary outcomes included complications defined by the Valve Academic Research Consortium 2 (VARC-2) criteria and major adverse cardiovascular events (MACEs), including mortality, stroke, and heart failure rehospitalization. …”
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Construction and evaluation of a triage assessment model for patients with acute non-traumatic chest pain: mixed retrospective and prospective observational study by Xuan Zhou, Gangren Jian, Yuefang He, Yating Huang, Jie Zhang, Shengfang Wang, Yunxian Wang, Ruofei Zheng

“…Results Multiple logistic regression analysis showed that age, smoking, coronary heart disease, hypertension, diabetes, hyperlipidemia, pain site, concomitant symptoms, and electrocardiograph, all of which are independent predictors of high-risk chest pain patients. …”
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Association between Serum Adiponectin and Atrial Fibrillation: A Case-Control Study Stratified by Age and Gender by Tongjian Zhu, Zhuo Wang, Songyun Wang, Wei Hu, Hui Chen, Jing Xie, Meng Wang, Kezhong Ma, Hong Jiang

“…All participants underwent echocardiography and heart rate variability tests. Biochemical parameters and adiponectin levels were also evaluated. …”
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Health profile of residents of retirement villages in Auckland, New Zealand: findings from a cross-sectional survey with health assessment by Kathy Peri, Michal Boyd, Martin J Connolly, Joanna B Broad, Dale Bramley, Zhenqiang Wu, Katherine Bloomfield, Joanna Hikaka, Annie Tatton, Cheryl Calvert, Ann-Marie Higgins

“…During the 2 weeks prior to survey, 34% received home supports and 10% personal care. Hypertension, heart disease, arthritis and pain were reported by over 40%. …”
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Prevalence, cessation, and geographical variation of smoking among middle-aged and elderly adults in China: A population-based study by Qingjia Zeng, Chongyang Zhang, Feiyu Su, Yanli Wan, Wen-jun Tu, Hongpu Hu

“…Additionally, the dose-response relationship indicated a more pronounced association between higher smoking pack-years and elevated health risks, including hypertension (aOR=1.30, 95% CI: 1.24-1.36), diabetes (aOR=1.26, 95% CI: 1.20-1.33), hyperlipidemia (aOR=1.22, 95% CI: 1.16-1.28), heart disease (aOR=1.40, 95% CI: 1.26-1.54), and stroke (aOR=1.23, 95% CI: 1.10-1.36). …”
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Clinical manifestations, para-clinical features and outcome of Iranian adults with respiratory syncytial virus (RSV) infection: a report from hospitalized patients by Maryam Shafaati, Abbas Shakoori Farahani, Mohammadreza Salehi, Mohammad Arabzadeh, Helya Bolouki Azari, Arman Soleimany, Maryam Edalatifard, Vahid Salimi, Alireza Abdollahi

“…Dyspnea, productive cough, and fever were the most common symptoms, with a mean symptom duration of 10.50 days. Ischemic heart disease, hypertension, and liver failure were common underlying conditions. …”
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Impact of Novel Guidelines on Multifactorial Control and Its Association with Mortality in Adult Patients with Hypertension and Newly Diagnosed Type 2 Diabetes: A 4-Year Prospectiv... by Ngoc-Thanh-Van Nguyen, Hoa Ngoc Chau, Nam Hoai Le, Hai Hoang Nguyen, Hoai-An Nguyen

“…At baseline, ischemic heart disease, dyslipidemia, and chronic kidney disease (CKD) were present in 54.9%, 67.1%, and 41.1% of patients. …”
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EFFECTS OF SMOKING ON CIRCADIAN ARTERIAL BLOOD PRESSURE PROFILE IN PATIENTS WITH NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROME AND CHRONIC KIDNEY DISEASE by Oksana Yadzhyn, Tetiana Solomenchuk

“…The following indicators have been determined: systolic blood pressure (SBP) - daytime, nighttime, and average daily (24 hours) (SBPd, SBPn, and SBPav); diastolic blood pressure (DBPd, DBPn, and DBPav); pulse pressure (PBPd, PBPn, and PBPav); time index (TI) for SBPd and SBPn (SBPd TI and SBPn TI) and DBP (DBPd TI and DBPn TI); heart rate (HR). To study the renal functional status in the examined patients, the urine albumin-creatinine ratio (ACR) was determined using the semi-quantitative method. …”
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Inhibition of the mTOR Pathway Exerts Cardioprotective Effects Partly through Autophagy in CLP Rats by Wen Han, Hao Wang, Longxiang Su, Yun Long, Na Cui, Dawei Liu

“…Recent studies have indicated that autophagy and myocardial energy depletion play a major role in myocardial dysfunction during sepsis, a mechanistic target of rapamycin (mTOR) as a master sensor of energy status and autophagy mediator; however, there are little data describing its role during sepsis in the heart. Methods. Cecal ligation and puncture (CLP) or sham operation (SHAM) was performed in rats. …”
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Alteration of Sarcoplasmic Reticulum Ca2+ Release in Skeletal Muscle from Calpain 3-Deficient Mice by Govindan Dayanithi, Isabelle Richard, Cédric Viero, Elsa Mazuc, Sylvie Mallie, Jean Valmier, Nathalie Bourg, Muriel Herasse, Isabelle Marty, Gérard Lefranc, Paul Mangeat, Stephen Baghdiguian

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Sessile Serrated Lesions: Searching for the True Prevalence and Risk Factors in China by Bing-Yue Yao, Li Zhang, Chuan-Xia Wu, Liang Zheng, Ben-Song Duan, Qin-Wei Xu, Jing-Jing Lian, Hai-Bin Zhang, Yu Wang, Jia Cao

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Effect of electroacupuncture on discomfort in patients undergoing colonoscopy: protocol for a multicentre, randomised, controlled clinical trial by Chao Lin, Wenting Chen, Yue Yong, Jiangang Song, Xiangyu Sun, Yongqiang Wang, Liyue Lu, Chunchun Wang, Kuangdi Xu

“…Secondary outcomes will include participants’ tolerance levels, including standard NRS scores for abdominal pain, bloating and anal discomfort reported by the participants, as well as heart rate(HR), blood pressure(BP), surgical pleth index, participant satisfaction, nurses’ and endoscopists’ evaluations, incidence of adverse events and salivary cortisol levels collected before EA and after colonoscopy.Ethics and dissemination Ethics approval was obtained from the Ethics Committee of Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine (number 2023-1327-94-01), Ethics Committee of Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine (number 2023LCSY059) and Ethics Committee of Wuxi Hospital Affiliated to Nanjing University of Traditional Chinese Medicine (number 2023-062-01). …”
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General practitioner-centered rural obesity management: Design, protocol and baseline data of the German HAPpEN pragmatic trial by Marika Haderer, Reiner Hofmann, Tina Bartelmeß, Laura König, Constanze Betz, Mirna Al Masri, Alisa Bader, Natascha von Schau

“…Primary outcomes include BMI, body weight, waist circumference, heart rate, blood pressure and parameters, while secondary outcomes assess quality of life, wellbeing, health literacy, social interaction, and digital therapy support. …”
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Acute Concurrent Exercise Improves Inhibitory Control Without Mediating the Role of Lactate: An Event-Related Potential Study by Ruei-Hong Li, Tai-Rui Chen, Nicholas D. Gilson, Marius Brazaitis, Yi-Ting Cheng, Hui-Fang Wu, Ji-Hang Lee, Yu-Kai Chang

“…Participants in the CE group engaged in 12-min of AE (40–59% of heart rate reserve [HRR]) coupled with 13-min of RE (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). …”
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Association of coronary revascularisation after physician-referred non-invasive diagnostic imaging tests with outcomes in patients with suspected coronary artery disease: a post ho... by Takao Kato, Moriaki Inoko, Naoya Matsumoto, Yukari Uemura, Masanao Naya, Mitsuru Momose, Satoshi Hida, Takao Yamauchi, Takatomo Nakajima, Eriko Suzuki, Tohru Shiga, Nagara Tamaki

“…We assessed the effect of revascularisation (within 90 days) in each diagnostic imaging stratum and the interaction between the two strata.Primary and secondary outcome measures Major adverse cardiac events (MACEs), including death, myocardial infarction, hospitalisation for heart failure and late revascularisation, were followed up for 1 year. …”
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Current applications and challenges in large language models for patient care: a systematic review by Felix Busch, Lena Hoffmann, Christopher Rueger, Elon HC van Dijk, Rawen Kader, Esteban Ortiz-Prado, Marcus R. Makowski, Luca Saba, Martin Hadamitzky, Jakob Nikolas Kather, Daniel Truhn, Renato Cuocolo, Lisa C. Adams, Keno K. Bressem

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Home-Based Intervention Tool for Cardiac Telerehabilitation: Protocol for a Controlled Trial by Francesca Mastorci, Maria Francesca Lodovica Lazzeri, Lamia Ait-Ali, Paolo Marcheschi, Paola Quadrelli, Massimiliano Mariani, Rafik Margaryan, Wanda Pennè, Marco Savino, Giuseppe Prencipe, Alina Sirbu, Paolo Ferragina, Corrado Priami, Alessandro Tommasi, Cesare Zavattari, Pierluigi Festa, Stefano Dalmiani, Alessandro Pingitore

“… BackgroundAmong cardiovascular diseases, adult patients with congenital heart disease represent a population that has been continuously increasing, which is mainly due to improvement of the pathophysiological framing, including the development of surgical and reanimation techniques. …”
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Effect of periodontal therapy on endothelial function and serum biomarkers in patients with periodontitis and established cardiovascular disease: a pilot study by Ana Molina, Nagore Ambrosio, María Molina, Eduardo Montero, Leire Virto, David Herrera, Elena Figuero, Mariano Sanz

“…AimTo investigate the effect of periodontal therapy on endothelial function of subjects with periodontitis in stages III or IV and established cardiovascular disease.Materials and methodsA triple-blinded, parallel groups, randomized clinical trial of 6 months duration, on patients with history of coronary heart disease and periodontitis in stages III or IV was performed. …”
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An Integrated Approach for Conducting long-term PM2.5 Exposure and Health Impact Assessments for Residents of a City-scale by Ming-Shing Ho, Ming-Yeng Lin, Chih-Da Wu, Jung-Der Wang, Li-Hao Young, Hui-Tsung Hsu, Bing-Fang Hwang, Perng-Jy Tsai

“…By reference to the results obtained from MMS9yr, using AQMS9yr and h_LUR9yr would respectively lead to the underestimation of the attributed fraction (AFs) ~21%–36% and 18%–26% for the 5 disease burdens, including ischemic heart disease, stroke, chronic obstructive pulmonary disease, lung cancer, and lower respiratory tract infection. …”
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