Cohort profile: Noncommunicable diseases and ideal cardiovascular health among people living with and without HIV in Zambia and Zimbabwe (NCDzz cohort) by Gilles Wandeler, Samuel Bosomprah, Cleophas Chimbetete, Belinda Varaidzo Chihota, Guy Muula, Carolyn Bolton-Moore, Tinei Shamu, Ardele Mandiriri, Esau Banda

“…Here, we describe the study design and population and evaluate their ideal cardiovascular health (ICVH) using the Life’s Simple 7 (LS7) score according to the American Heart Association.Participants Antiretroviral therapy-naïve people living with HIV (PLWH) and people living without HIV (PLWOH) 30 years or older were recruited from three primary care clinics in Lusaka and Harare, and underwent comprehensive clinical, laboratory and behavioural assessments. …”
Get full text

Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs by Masaki Shibuya, Masafumi Fujinaka, Mako Yonezawa, Natsumi Nishimura, Hitoshi Uchinoumi, Hiroshi Sunahara, Kenji Tani, Eiji Kobayashi, Motoaki Sano

“…The hydrogen concentrations of blood samples collected from the left internal jugular vein 3 cm to the heart from the tip of the infusion line were 6.4 (30 min), 4.7 (60 min), 4.9 (90 min), and 5.3 (120 min) ppb <i>w</i>/<i>w</i>, respectively. …”
Get full text

Immunologic and inflammatory consequences of SARS-CoV-2 infection and its implications in renal disease by Hiam Naiditch, Michael R. Betts, H. Benjamin Larman, Moshe Levi, Avi Z. Rosenberg

“…In this context, endovascular neutrophil extracellular trap (NET) formation and microthrombi development can be seen in the lungs and other critical organs throughout the body, such as the heart, gut, and brain. The kidney may be among the most impacted extrapulmonary organ by SARS-CoV-2 infection owing to a high concentration of ACE2 and exposure to systemic SARS-CoV-2. …”
Get full text

Development and validation of the age-associated dementia policy (AgeD-Pol) computer simulation model in the USA and Europe by Anand Viswanathan, Lee H Schwamm, Krishna P Reddy, Emily P Hyle, Fatma M Shebl, Kenneth A Freedberg, Julia H A Foote, Yiqi Qian, Shibani S Mukerji, Nattanicha Wattananimitgul, Ankur Pandya

“…We then performed external validation of the model using data from the Framingham Heart Study, the Rotterdam Study and Kaiser Permanente Northern California (KPNC). …”
Get full text

Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model by Tu Zhilan, Zhang Zengyu, Jin Pengpeng, Yang Hualan, Li Chao, Xi Yan, Guo Zimin, Hou Shuangxing, Li Weiwei

“…Introduction: Salidroside (SAL), extracted from Rhodiola rosea, has been widely used in coronary heart disease and myocardial ischemia for decades. …”
Get full text

Implementasi Kebijakan Pengembangan Pariwisata Pada Objek Wisata Alam Goa Akbar Di Kabupaten Tuban by Irdina Iffata Qottrunnada, Ananta Prathama

“…The Goa Akbar tourist site, managed by the Tuban Regency Government, holds significant potential as a key source of local revenue in the tourism sector due to its strategic location in the heart of Tuban city. However, its development policy implementation still shows deficiencies. …”
Get full text

Associations between Life’s Essential 8 and liver function: a cross-sectional study by Qiaoli Liang, Menglong Zou, Ziming Peng

“…BackgroundLife’s Essential 8 (LE8) score, developed by the American Heart Association, assesses cardiovascular health using eight components: diet, physical activity, nicotine exposure, sleep health, body mass index, lipids, blood glucose, and blood pressure. …”
Get full text

Clinical Significance of Screening Electrocardiograms for the Administration of Propranolol for Problematic Infantile Hemangiomas by James D. Phillips, Tyler Merrill, J. Reed Gardner, R. Thomas Collins, Jenika Sanchez, Adam B. Johnson, Brian K. Eble, Larry D. Hartzell, Jay M. Kincannon, Gresham T. Richter

“…Screening electrocardiograms (ECG) are performed prior to the initiation of propranolol to minimize the risk of exacerbating undiagnosed heart block. How ECG results affect subsequent propranolol usage and patient management remains unclear. …”
Get full text

Economic burden of Type 2 diabetes in Iran in 2022 by Amin Mohammadi, Mahshad Goharimehr, Ali Darvishi, Ramin Heshmat, Ensieh Nasli Esfahani, Gita Shafiee, Afshin Ostovar, Rajabali Daroudi

“…Chronic kidney disease accounted for the largest proportion, followed by ischemic heart disease (IHD), and T2D itself. The total economic burden of T2D and its attributable complications in Iran in 2022, was estimated to be $2,905.7 million US dollars (US$-PPP 10,324.2 million). …”
Get full text

The role of oxidized non-coding RNAs of the epigenome in the development of human diseases (literature review) by S.S. Ostrovska, Ye.N. Dychko, T.Ye. Shumna, G.I. Titov, O.S. Trushenko, P.G. Gerasymchuk, I.Y. Burega

“…Circulating micro RNAs that are sensitive to oxidative stress are reported to be potential biomarkers of cardiovascular diseases, including myocardial infarction, hyper­trophy, ischemia/reperfusion, and heart failure. Many studies are aimed at using microRNAs for therapeutic purposes. …”
Get full text

Depression Paradox in Cardiovascular Outcomes of Adult Patients with Obstructive Sleep Apnea: Insights from 2 Million Nationwide Hospitalizations by Rupak Desai, Sashwath Srikanth, Shaylika Chauhan, Zainab Gandhi, Warda Shahnawaz, Aleen Rahman, Bisharah Rizvi, Akhil Jain

“…OSA+D+ cohort had a higher prevalence of hypertension, diabetes, hyperlipidemia, congestive heart failure, anemia, smoking, substance abuse, prior myocardial infarction (MI), transient ischemic attack (TIA), TIA/stroke, and venous thromboembolism than the OSA+D- group (all P < 0.001). …”
Get full text

Case report: Detecting giant cell arteritis in [68Ga]Ga-DOTA-Siglec-9-PET/CT by Simon M. Petzinna, Jim Küppers, Benedikt Schemmer, Anna L. Kernder, Anna L. Kernder, Claus-Jürgen Bauer, Leon von der Emde, Babak Salam, Jörg H. W. Distler, Anja Winklbauer, Markus Essler, Valentin S. Schäfer

“…The [68Ga]Ga-DOTA-Siglec-9 PET/CT scan revealed increased tracer uptake (SUVmax) in the subclavian artery (2.5), aortic arch (2.9), and heart (2.9). Notably, the increased uptake in the descending aorta (3.5) abruptly diminished to 2.2 when passing the diaphragm, with no changes in vessel caliber observed in CT. …”
Get full text

The efficacy of Artichoke leaf extract conjugated with organic zinc nanoparticles on growth, carcass traits and blood biochemical parameters of broilers by Elwy A. Ashour, Ahmed K. Aldhalmi, Mahmoud Kamal, Salem S. Salem, Samir A. Mahgoub, Abdulmohsen H. Alqhtani, Mahmoud Madkour, Ahmed A. Elolimy, Mohamed E. Abd El-Hack, Ayman A. Swelum

“…There were no notable variations in carcass features between treatments, except for the percentage of carcass, dressing, thigh, heart, and intestine cecum in the control group. …”
Get full text

Perioperative nursing management of transcatheter edge-to-edge repair (经导管二尖瓣缘对缘修复术围手术期护理) by LIU Yuan (刘苑), LAI Jianqing (赖间清), DING Fei (丁菲), HUANG Huifen (黄惠芬)

“…The comprehensive interventions including enhanced recovery after surgery, respiratory exercise, pain control, catheter maintenance and standard health education before discharge were carried out to relieve symptoms of heart failure, improve self-care ability and quality of life of patients after transcatheter edge-to-edge repair. …”
Get full text

Change in Atrial Fibrillation Burden over Time in Patients with Nonpermanent Atrial Fibrillation by Philipp Krisai, Stefanie Aeschbacher, Matthias Bossard, Elena Herber, Steffen Blum, Pascal Meyre, Thilo Burkard, Michael Kühne, Stefan Osswald, Beat A. Kaufmann, David Conen

Get full text

INSTITUTIONAL GLOBALIZATION AS A SYSTEM OF INTEGRATION THE PHENOMENON OF THE POSTMODERN DEVELOPMENT by V. V. Zinchenko

“…All these were very important components of the new paradigm, although they do not exhaust the problem. In the heart of postmodernism is a mass identity as a spiritual substance, while the more recently mass of people to realize themselves as natural and social beings. …”
Get full text

A randomized sequential allocation study on the optimum programmed intermittent epidural boluses interval time with different concentrations of ropivacaine combined with the dural... by Jingjing Mao, Yi Chen, Linsen Sun, Xiaoxiao Xu, Kai Xu, Tingting Ren, Xiangsheng Xiong, Weibing Zhao, Weibing Zhao

Get full text

Trends in palliative care utilization among older adult decedents with and without cancer in Taiwan: a population-based comparative studyResearch in context by Yu-Tai Lo, Tzu-Jung Chuang, Yu-Tung Huang, Yi-Lin Wu, Yi-Ching Yang, Chung-Yi Li

“…Summary: Background: The leading causes of death among the older adults have shifted from cancer to non-cancer conditions such as ischemia heart diseases, stroke, and dementia, affecting end-of-life care needs. …”
Get full text

Risk analysis of cardiovascular toxicity in patients with lymphoma treated with CD19 CAR T cells by Yang Liu, Xiaoshuang Yuan, Xu Yang, Bo Yang, Guangyang Liu, Xiao Xu, Sanbin Wang, Zhixu He, Feiqing Wang, Yanju Li

“…Additionally, the incidences of heart failure (HF), cardiomyopathy, cardiac arrest, and other CV events are 3%, 0.6%, 1.3%, and 2.5%, respectively. …”
Get full text

Molecular simulations reveal intricate coupling between agonist-bound β-adrenergic receptors and G protein by Yanxiao Han, John R.D. Dawson, Kevin R. DeMarco, Kyle C. Rouen, Khoa Ngo, Slava Bekker, Vladimir Yarov-Yarovoy, Colleen E. Clancy, Yang K. Xiang, Surl-Hee Ahn, Igor Vorobyov

“…Using advanced computer modeling and simulation, we identified atomistic-level structural, dynamic, and energetic mechanisms of norepinephrine (NE) and stimulatory G protein (Gs) interactions with β-adrenergic receptors (βARs), crucial GPCRs for heart function regulation and major drug targets. …”
Get full text