Isoproterenol mechanisms in inducing myocardial fibrosis and its application as an experimental model for the evaluation of therapeutic potential of phytochemicals and pharmaceutic... by Lujain Bader Eddin, Mohamed Fizur Nagoor Meeran, Niraj Kumar Jha, Samer N. Goyal, Shreesh Ojha

“…Many experimental studies have demonstrated that fibrotic injury in the heart is reversible; therefore, it is vital to understand different molecular mechanisms that are involved in the initiation, progression, and resolution of cardiac fibrosis to enable the development of antifibrotic agents. …”
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Haploidentical stem cell transplantation with posttransplant cyclophosphamide in children with Wiskott–Aldrich syndrome: a case report by Le Nguyen Ngoc Quynh, Binh Nguyen Thanh, Lien Luong Thi, Thuy Nguyen Thi Dieu, Duong Dang Anh, Pamela P. Lee, Tung Cao Viet, Dien Tran Minh

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Deep Vein Thrombosis and Pulmonary Embolism Secondary to Thrombophilic Disorder: A Case Report by Satbir Kaur Malik, Vineetha Naga Lakshmi Giduturi, Sindhuri Goud Nimmala, Vijayashree Gokhale

“…Deep Vein Thrombosis (DVT) is a common condition that is part of venous thromboembolism disorders and represents the third most common cause of death from cardiovascular disease, following heart attacks and strokes. Authors hereby, report a rare and complicated case involving a 44-year-old male patient who experienced Pulmonary Embolism (PE), DVT, IDA and underlying abnormalities in two key anticoagulant proteins: Protein C and Protein S. …”
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Lyme neuroborreliosis as initial expression of Lyme disease in an elderly patient by Emidio Mata, Bárbara Lage Garcia, André Pereira, Joana Rego, Flávia Santos, Carlos Fernandes, Jorge Cotter

“…Background: Lyme disease (LD) is a multisystemic infection caused by Borrelia burgdorferi and transmitted by Ixodes ticks, affecting the skin, nervous system, heart and joints. Neuroborreliosis (LNB), a nervous system manifestation of LD, occurs in 10–15% of cases and may present with neurological symptoms at varying stages. …”
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The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo by Jacob Schade Engbjerg, Vincenzo Costanzo, Donato Sardella, Luca Bordoni, Steen Jakobsen, Luciano D'Apolito, Jørgen Frøkiær, Francesco Trepiccione, Giovambattista Capasso, Sebastian Frische

“…PET imaging using 11C-labelled ASP+ showed accumulation in the liver, heart, and kidney. Fluorescence emission spectra recorded in vitro of ASP+ alone and in the presence of albumin using both 1-photon excitation and two-photon excitation showed that albumin strongly enhance the emission from ASP+ and induce a shift of the emission maximum from 600 to 570 nm. …”
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Renal Heme Oxygenase-1 Induction with Hemin Augments Renal Hemodynamics, Renal Autoregulation, and Excretory Function by Fady T. Botros, Leszek Dobrowolski, L. Gabriel Navar

“…Mean arterial pressure and heart rate were not different (115±5 mmHg versus 112±4 mmHg and 331±16 versus 346±10 bpm). …”
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The comparison of biodistribution of glutathione PEGylated nanoliposomal doxorubicin formulations prepared by pre‐insertion and post‐insertion methods for brain delivery in normal... by Amin Mehrabian, Saba Dadpour, Mohammad Mashreghi, Javad Zarqi, Anis Askarizadeh, Ali Badiee, Leila Arabi, Seyedeh Alia Moosavian, Mahmoud Reza Jaafari

“…Compared to the pre‐inserted formulation and Caelyx®, the post‐inserted formulations' concentration was lower in the heart and higher in brain tissues, resulting in boosting the brain concentration of accumulated doxorubicin with fewer possible side effects, including cardiotoxicity. …”
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Higher AVCO2 and Lactate Gradient Combined with SOFA Score as a Mortality Predictor during the 6-Hours of Resuscitation of Septic Shock by Morteza Talebi Doluee, Sahar Azam Ghasemzadeh, Ahmad Bagheri Moghadam, Zahra Abbasishaye, Davood Soroosh, Elnaz Vafadar Moradi

“…Of these patients, 15 (17%) died, of them 8 (53.33%) were male, 14 (93%) were diabetic, 11(73.33%) were hypertensive, 11 (73.33%) had ischemic Heart disease and 9 (60%) patients had Chronic Obstructive Pulmonary Disease (COPD). …”
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In-depth proteomic profiling identifies potentiation of the LPS response by 7-ketocholesterol by Iain R. Phair, Magdalena Sovakova, Noor Alqurashi, Raid B. Nisr, Alison D. McNeilly, Douglas Lamont, Graham Rena

“…In patients with stable coronary artery disease, plasma levels of 7-ketocholesterol (7-KC), found at high levels in atherosclerotic lesions, predict risk of incident heart failure dose dependently, potentially contributing to disease aetiology. …”
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Lung Transplantation in Patients with High Lung Allocation Scores in the US: Evidence for the Need to Evaluate Score Specific Outcomes by Jeremiah A. Hayanga, Alena Lira, Tedi Vlahu, Jingyan Yang, Jonathan K. Aboagye, Heather K. Hayanga, James D. Luketich, Jonathan D’Cunha

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Examining the Specificity of Smartphone ECG Devices in Decision-Making for ST-Elevation Myocardial Infarction and Non-ST-Elevation Myocardial Infarction by Sahil mahajan, Salil Garg, Yogendra Singh, richa sharma, Tanuj Bhatia, nitin chandola, deeksha agarwal

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Local anesthetic systemic toxicity after brachial plexus block with ropivacaine: a case report by A.G. Tutunnyk, N.V. Mynka, U.U. Kobelyatskyy

“…During this time, her blood pressure was 132/83 mmHg, heart rate 82 beats/min. oxygen saturation 97%. No changes were observed on the ECG. …”
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Subchronic Toxicity Study of Alternanthera philoxeroides in Swiss Albino Mice Having Antioxidant and Anticoagulant Activities by Shahad Saif Khandker, Morshed Alam, Forhad Uddin, Ummay Mahfuza Shapla, Nafisa Lubna, Tanusree Amy Mazumder, Mahfuza Marzan, Milon Mondal, Md Ibrahim Khalil, Nurul Karim, Md Salman Shakil, Md Sakib Hossen

“…Following that, the in vivo toxicological effects of methanolic extracts of A. philoxeroides using different doses on the kidney, heart, lung, liver, stomach, brain, and blood of female Swiss Albino mice were investigated. …”
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From a dictionary to an atlas: segmental mapping of the linguistic picture of the world by S. N. Gagarin

“…'At the heart of any language lies a vision. It embraces the world around us in myriads of complex ways. …”
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Adherence patterns, risk factors and complications among patients with tuberculosis: a cross-sectional study at Nsawam Government Hospital by Abraham Norman Nortey, Amanda Adjoda, Amidu Alhassan, Godfred Yawson Scott

“…Participants earning less than 500 Ghana Cedis (Ghc) (adjusted OR (aOR)=8.85. 95% CI (1.59 to 49.24), p=0.013), patients with TB who indicated having complication (joint pain, spinal pain, heart disorders, liver or kidney problems) as a result of TB (aOR=2.81, 95% CI (1.58 to 4.99), p<0.001), respondents who mentioned living with people infected with TB (aOR=3.23. 95% CI (1.24 to 8.37), p=0.016) were the independent predictors of adherence to TB medication.Conclusion The study findings revealed that participants exhibited commendable adherence to TB medication. …”
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Hypolipidemic effect of coffee silver skin in rats fed a high-fat diet by Ayman Mohammed El-Anany, Rehab Farouk M. Ali

“…At the time of sacrifice, the weights of heart, liver, kidneys, epididymal fat and retroperitoneal fat of the experimental rats with respect to body weight were recorded. …”
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Neutrophil Extracellular Trap Production in Patients with Colorectal Cancer In Vitro by J. J. R. Richardson, C. Hendrickse, F. Gao-Smith, D. R. Thickett

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Fibromyalgia Detection and Diagnosis: A Systematic Review of Data-Driven Approaches and Clinical Implications by Anirudh Atmakuru, Subrata Chakraborty, Massimo Salvi, Oliver Faust, Prabal Datta Barua, Makiko Kobayashi, Ru San Tan, Filippo Molinari, Abdul Hafeez-Baig, U. Rajendra Acharya

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Reactivation of mTOR signaling slows neurodegeneration in a lysosomal sphingolipid storage disease by Hongling Zhu, Y. Terry Lee, Colleen Byrnes, Jabili Angina, Danielle A. Springer, Galina Tuymetova, Mari Kono, Cynthia J. Tifft, Richard L. Proia

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Echocardiographic Features of Cardiomyopathy in Emery-Dreifuss Muscular Dystrophy by Michał Marchel, Agnieszka Madej-Pilarczyk, Agata Tymińska, Roman Steckiewicz, Janusz Kochanowski, Julia Wysińska, Ewa Ostrowska, Paweł Balsam, Marcin Grabowski, Grzegorz Opolski

“…We did not present any significant differences between EDMD1 and EDMD2 in terms of the morphology and the function of the heart.…”
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