A cost-utility analysis of adding SGLT2 inhibitors for the management of type 2 diabetes with chronic kidney disease in Thailand by Natthakan Chitpim, Pattara Leelahavarong, Juthamas Prawjaeng, Sakditat Ittiphisit, Varalak Srinonprasert, Tanawan Kongmalai

“…However, the analysis solely focuses on renal benefits, excluding other advantages like cardiovascular and heart failure protection.…”
Get full text

Clinical Predictors of Hospital-acquired Pneumonia Associated with Acute Ischemic by Alexis Suárez Quesada, Ezequiel López Espinosa, Noelsis García Verdecia, Miguel Ángel Serra Valdés

“…The following independent factors were identified: Glasgow Coma Scale ≤ 11 (OR: 26.099; 95 % CI 7.164-85.075), history of chronic obstructive pulmonary disease (OR: 8.896; 95 % CI 1.203-65.779), dysphagia (OR: 7.652; 95 % CI 2.369- 24.720), history of heart failure (OR: 4.583; 95 % CI 1.240- 16.932) and dysarthria/severe motor aphasia (OR: 4.222; 95 % CI 1.374- 12.975). …”
Get full text

Evaluation of physicians' screening practices and knowledge levels regarding atrial fibrillation in patients over 65 years of age: A prospective study by Emre Bulbul, Erhan Simsek, Muhammet Kizmaz

“…Early detection and management are essential to mitigate severe complications such as stroke and heart failure. These efforts are crucial in primary care, where family medicine practitioners are key. …”
Get full text

A Narrative Review of Key Risk Factors for Severe Illness Following SARS-CoV-2, Influenza Virus, and Respiratory Syncytial Virus Infection by Angela Branche, Mayur Ramesh, Beverly Francis

“…Additionally, immunocompromising conditions and pre-existing comorbidities, including underlying cardiovascular (e.g., congestive heart failure) and respiratory diseases (e.g., chronic obstructive pulmonary disease), diabetes, chronic kidney disease, and obesity, are key factors that predispose individuals to SARS-CoV-2-, influenza-, and RSV-related severe outcomes. …”
Get full text

Validating the Hypoglycaemic and Hypotensive Roles of Salvia serotina (Chicken Weed) in Normal Healthy Sprague–Dawley Rats by Tameika Bartley, Paul Reese, Sophie Turfus, Ruby Alexander-Lindo

“…Aqueous, hexane, ethyl acetate, and methanol crude extracts of S. serotina L. were investigated for their anti-oxidant activities and hypoglycaemic and hypotensive effects in normal, healthy Sprague–Dawley rats using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, oral glucose tolerance test (OGTT), and the CODA noninvasive blood pressure system to determine systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and heart rate (HR). The aqueous extract caused a free radical scavenging effect with an IC50 value of 10.2 ± 1.01 µg/mL versus vitamin C (9.42 ± 1.01 µg/mL). …”
Get full text

Examining the etiology and pregnancy outcomes of 152 critically ill pregnant patients in the Intensive Care Unit by Weiman Liu, Junyou Su, Sumei Wang

“…Results The results showed that the main obstetric factors leading to ICU admission were pregnancy-related hypertensive disease, postpartum hemorrhage, and acute fatty liver of pregnancy; the non-obstetric factors included either pregnancy complicated by heart disease, sepsis, or malignant tumors. The maternal mortality rate was higher in the non-obstetric direct factor group than in the obstetric direct factor group (22.12% vs. 6.25%, p = 0.016). …”
Get full text

Enhance health evidence quality in classification tasks: A triangulation approach utilizing case-based reasoning and process features by Ruihua Guo, Ross Smith, Qifan Chen, Angus Ritchie, Simon Poon

“…This study proposed an integrated approach to enhance the quality of health evidence from a classification task for predicting Medicare's Diagnosis-Related Groups of ischemic heart disease (IHD) patients. Methods Eligible participants were identified from the Medical Information Mart for Intensive Care IV (MIMIC IV), a publicly available hospital database. …”
Get full text

Persistent Primary Hyperparathyroidism, Severe Vitamin D Deficiency, and Multiple Pathological Fractures by Victoria Mendoza-Zubieta, Mauricio Carvallo-Venegas, Jorge Alberto Vargas-Castilla, Nicolás Ducoing-Sisto, Alfredo Alejandro Páramo-Lovera, Lourdes Josefina Balcázar-Hernández, Julián Malcolm Mac Gregor-Gooch

“…Blood pressure was 100/80, heart rate was 86 per minute, and body mass index was 19 kg/m2. …”
Get full text

Nurse-Led Self-Management Support After Organ Transplantation – A Multicenter, Stepped-Wedge Randomized Controlled Trial by Regina van Zanten, Monique van Dijk, Joost van Rosmalen, Joost van Rosmalen, Denise K. Beck, AnneLoes van Staa, Ann Van Hecke, Ann Van Hecke, Emma K. Massey

“…In this unblinded multi-center stepped-wedge randomized controlled trial the effectiveness of the nurse-led ZENN-intervention was tested in promoting self-management skills in comparison to standard care among heart, lung and kidney transplant recipients. This intervention is based on behaviour change theories and was conducted in four sessions over 6 months at the outpatient clinic. …”
Get full text

Nicotine-free vape liquids containing essential oils of peppermint, lavender, and tangerine: safety and efficacy profiles by Rahmad Aji Prasetya, Djamilah Arifiyana, Zain Budi Syulthoni

“…The efficacy test showed that subjects who used vape liquids with essential oils (F1-F4) experienced a significant decrease in heart rate and systolic blood pressure. At the same time, 50% had a lower post-test STAI score, indicating a decrease in anxiety, although it was not statistically significant. …”
Get full text

hERGAT: predicting hERG blockers using graph attention mechanism through atom- and molecule-level interaction analyses by Dohyeon Lee, Sunyong Yoo

“…Abstract The human ether-a-go-go-related gene (hERG) channel plays a critical role in the electrical activity of the heart, and its blockers can cause serious cardiotoxic effects. …”
Get full text

Study on thermal and physiological responses during summer while moving between academic buildings under different walking conditions by Jiahao Yang, Haiyan Li, Zhaosong Fang, Yongcai Li, Fangqi Lu, Tongye Guo, Xiang Zhang, Chang Lin, Jun Lu

“…The findings are as follows: (1) Subjects exposed to short-term sunlight showed an average HR (heart rate) increase of 3.4 beats/min (0.8 m/s), 3.9 beats/min (1.2 m/s), and 4.2 beats/min (1.6 m/s) compared to non-exposed individuals; the maximum Tac (auditory canal temperature) difference was 0.15 °C, and the maximum differences in metabolic rate and heat storage were 14.8 W/m2 and 12.2 W/m2, respectively; (2) Walking speeds should be kept below 2.09 m/s (non-exposed) and 1.53 m/s (expose) to avoid heat risks; (3) There is a discrepancy between the simulated and actual thermal indices. …”
Get full text

The impact of chronic disease diagnoses on smoking behavior change and maintenance: Evidence from China by Xinxin Chi, Xihua Liu, Cong Li, Wen Jiao

“…We found that diagnoses of cancer, heart disease, and stroke reduced smoking rates by 16% (95% CI: -24 – -8), smoking intensity by 0.31 (95% CI: -0.46 – -0.15), and had lasting impacts on smoking cessation behavior (one wave after diagnosis ATT= -0.17; 95% CI: -0.34 – -0.00, two waves after diagnosis ATT= -0.17; 95% CI: -0.37–0.03). …”
Get full text

High-Flow Nasal Cannula: A Promising Oxygen Therapy for Patients with Severe Bronchial Asthma Complicated with Respiratory Failure by Wanru Geng, Wuliji Batu, Shuhong You, Zhaohui Tong, Hangyong He

“…However, HFNC was more efficient than COT in elevating PO2 in patients with severe bronchial asthma complicated with respiratory failure, while no statistically significant difference in PCO2 reduction was found between the two groups. Heart rate (HR) and respiratory rate (RR) between the two groups on admission (0 h) and at 2, 8, 24, and 48 h after admission were compared. …”
Get full text

Cardiac safety of gamithromycin in ewes by Orhan Corum, Burak Dik, Emre Bahcican, Emre, Hatice Eser, Hatice, Ayse Er, Enver Yazar

“…</p> <p><br /> <strong>Conclusion:</strong> It may be stated that single dose (6 mg/kg, SC) gamithromycin administration has no distinctive side effects on the heart, liver and kidney functions and hemogram values in sheep.…”
Get full text

Effectiveness and Safety of the Coadministration of Rifampin and Warfarin versus Direct Oral Anticoagulants: A Cohort Study by Ju-Chieh Wung, Chia-Chen Hsu, Chi-En Wang, Yaa-Hui Dong, Chia-Chieh Lin, Szu-Yu Wang, Shih-Lin Chang, Yuh-Lih Chang

Get full text

Developing a new clinical governance framework for chronic diseases in primary care: an umbrella review by Walter Ricciardi, Gianfranco Damiani, Alessandra Buja, Vincenzo Baldo, Mark H Ebell, Roberto Toffanin, Mirko Claus

Get full text

Exercise intensity and reliability during recreational team handball training for 50–77-year-old unexperienced women by Rita Pereira, Peter Krustrup, Carlo Castagna, Carlos Resende, Ivone Carneiro, José Magalhães, Susana Póvoas

“…This study analyzed the physiological and physical demands of recreational team handbal (RTH) and the training sessions’ (matches) intensity variability in 50–77-year-old postmenopausal women ( n = 20) without prior experience with the sport. Heart rate (HR), blood lactate, rating of perceived exertion (RPE), distance covered, time spent in different locomotor categories, accelerations, decelerations, Player Load (PL), game actions and fun levels were evaluated in 245 matches, played indoor ( n = 130) or outdoor ( n = 115), as small sided games (3×15-min periods). …”
Get full text

Effects of Anti-Obesity Strategies on Bone Mineral Density: A Comprehensive Meta-Analysis of Randomized Controlled Trials by Myung Jin Kim, Seonok Kim, Han Na Jung, Chang Hee Jung, Woo Je Lee, Yun Kyung Cho

Get full text

Deaths during Sexual Activity by Agnė Okulevičiūtė, Sigitas Chmieliauskas, Sigitas Laima, Diana Vasiljevaitė, Jurgita Stasiūnienė

“…Concurrent findings included atherosclerotic changes in the heart, internal organ hyperemia and edema, hepatic steatosis, renal cyst, and a lack of ethyl alcohol in blood but 0.17 ‰ presence in urine according to toxicology analysis. …”
Get full text