Avoidable factors associated with maternal death from postpartum haemorrhage: a national Malawian surveillance study by Arri Coomarasamy, Maria Lisa Odland, Luis Gadama, David Lissauer, Fannie Kachale, Chifundo Ndamala, Abi Merriel, Catriona Waitt, Hussein H Twabi, Annie Kuyere, Marthe Onrust, Jennifer Riches, Yamikani Chimwaza, Rosemary Bilesi, Lumbani Makhaza, Regina Makuluni, Laura Munthali, Owen Musopole, Deborah A Phiri, James Jafali

“…Global efforts must now be focused on strategies that address these weaknesses, strengthening health systems and empowering healthcare workers to reduce maternal deaths from PPH.…”
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Characteristic alterations of gut microbiota and serum metabolites in patients with chronic tinnitus: a multi-omics analysis by Jiang Wang, Jia-Hui Xiang, Xu-Yuan Peng, Min Liu, Le-Jia Sun, Min Zhang, Li-Yuan Zhang, Zhi-Bin Chen, Zheng-Quan Tang, Lei Cheng

“…Severe cases may lead to sleep disorders, anxiety, and depression, subsequently impacting patients’ lives and increasing societal healthcare expenditures. However, tinnitus mechanisms are poorly understood, and effective therapeutic interventions are currently lacking. …”
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Medication related osteonecrosis (MRONJ) in the management of CTIBL in breast and prostate cancer patients. Joint report by SIPMO AND SIOMMMS by Francesco Bertoldo, Cristina Eller-Vainicher, Vittorio Fusco, Rodolfo Mauceri, Jessica Pepe, Alberto Bedogni, Andrea Palermo, Umberto Romeo, Giuseppe Guglielmi, Giuseppina Campisi

“…Conclusions: Despite obvious weaknesses of the available international literature, the Expert Panel recognized the need to tailor separate MRONJ preventive approach for breast and prostate cancer patients on adjuvant endocrine therapy who begin low-dose BMA therapy to prevent CTIBL and provided this practical guidance for bone specialists and oral healthcare providers. In view of a MRONJ risk for BC and PC patients receiving low-dose BMAs, which approximates that of patients with osteoporosis and other non-malignant diseases undergoing similar treatment schedules, the SIPMO-SIOMMMS Expert Panel recognizes the need for less stringent preventive strategies than those already developed for BC or PC patients with bone metastases taking HD-BMAs.…”
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Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia by A.B. Movsisyan, A.V. Kuroyedov, M.A. Arkharov, V.V. Prokhorenko, I.A.Chepurnov

“…., glaucoma) are among strate gic tasks for the healthcare system.</i> </p> <p> <i><b>Keywords</b>: primary open-angle glaucoma, glaucoma diagnosis, glaucoma epidemiology, prognosis.…”
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Increased Early‐Mortality in Children With Solid Tumors During the COVID‐19 Pandemic in a Middle‐Income Country by Oscar Ramirez, Vivian Piedrahita, Santiago Bolivar, Karina Grillo, Adriana Linares, Carlos Pardo, Martha Piña, Amaranto Suarez, Carlos A. Portilla, Jesus Ardila, Viviana Lotero, Luz A. Urcuqui, Angela Trujillo, Patricia Montenegro, Luis E. Bravo, Paula Aristizabal, VIGICANCER Working Group

“…Conclusions We observed increased early‐mortality for solid tumors, particularly bone tumors and retinoblastoma, likely attributed to more advanced‐stage presentation and loss of treatment effectiveness due to healthcare disruptions. Early‐mortality was higher in patients with public insurance, a vulnerable population that warrants attention.…”
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Incidence of unintended pregnancies and pregnancy experience among adolescents living with perinatally-acquired HIV in West Africa: a mixed-method study by Désiré Lucien Dahourou, Clément Tisseron, Caroline Yonaba, Joël Djaha, Marie-Sylvie N’Gbeche, Corinne Moh, Kouakou Kouadio, Patricia Nindjin, François Eboua, Belinda Bouah, Karen Malateste, Jean-Claude Azani, Eulalie Kangah, Elisabeth Thio, Philippe Msellati, Julie Jesson, Valériane Leroy, for the IeDEA West-African Collaboration

“…HIV care programs should include interventions that improve awareness and access to sexual and reproductive healthcare, including contraception, to meet the needs of ALHIV in West Africa. …”
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The natural immune molecules urinary Tamm–Horsfall protein and pentraxin 3 as predictors for recurrent urinary tract infection severity: a single-center self-control study by Zongping Li, Yingru Xu, Qian Wang, Gang Yuan, Jing Shu, Shiwei Liu, Xuezhong Gong

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Development scheme for the Traditional Chinese Medicine nursing outpatient clinic (中医特色护理门诊的构建方案及思考) by SU Xiaonan (苏小南), KOU Jialiang (寇嘉靓), LI Yanli (李艳丽), CHEN Yiyun (陈艺芸), YANG Meijie (杨梅洁), JIA Xue (贾雪), CHANG Yan (常燕), MA Zeyun (马泽云), ZHAO Pei (赵培), GAO Ning (高宁)

“…Adhering to the principles of holistic view of TCM and nursing by syndrome differentiation, it aims to meet diversified health needs of patients by providing TCM nursing techniques, and plays a unique role in disease prevention and healthcare. It is a continuation of high-quality nursing and embodiment of patient-centered nursing service. …”
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Inappropriate medication prescribing, polypharmacy, potential drug-drug interactions and medication regimen complexity in older adults attending three referral hospitals in Asmara,... by Nuru Abdu, Saleh Idrisnur, Hanae Said, Lude Kifle, Natnael Habte, Semira Ghirmai, Tomas Tewelde, Senai Mihreteab Siele, Eyasu H. Tesfamariam

“…Conclusion Inappropriate medication prescribing and clinically significant drug-drug interactions were common among older adults, highlighting the need for immediate attention from policymakers, program managers, and healthcare professionals.…”
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Serious Bacterial Infections and Hepatitis C Virus Among People Who Inject Drugs: A Syndemic or Intertwined Epidemics? by Thomas J. Stopka, Robin M. Nance, L. Sarah Mixson, Hunter Spencer, Judith I. Tsui, Judith M. Leahy, Mai T. Pho, Jean DeJace, Judith Feinberg, April M. Young, Wei-Teng Yang, Amelia Baltes, Eric Romo, Randall T. Brown, Kerry Nolte, William C. Miller, William A. Zule, Wiley D. Jenkins, Joseph A. Delaney, Peter D. Friedmann

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Hospitalizations with post-traumatic stress disorder in France between 2013 and 2022: a nationwide retrospective study by Alice Demesmaeker, Florian Dufrenois, Chloé Saint-Dizier, Guillaume Vaiva, Antoine Lamer, Mathilde Horn, Fabien D’Hondt

“…Despite the significant impact of PTSD, specific data on healthcare utilization related to PTSD remain limited. …”
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The incidence of incomplete abortion and the prevalence of abortion-related morbidity in South African public hospitals, 2018 by D N Conco, J Levin, B Komane, K Blanchard, T Bessenaar, N G Nkosi, S Fonn

“…However, evidence suggests that women encounter barriers to accessing safe abortions, including stigma, resistance from healthcare providers, a shortage of trained professionals and a lack of awareness of their rights. …”
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Global, regional, and national burden inequality of chronic kidney disease, 1990–2021: a systematic analysis for the global burden of disease study 2021 by Jingxun Guo, Jingxun Guo, Zhen Liu, Zhen Liu, Pengjun Wang, Heming Wu, Kai Fan, Kai Fan, Jianbo Jin, Jianbo Jin, Lan Zheng, Lan Zheng, Zeyu Liu, Zeyu Liu, Renyi Xie, Renyi Xie, Renyi Xie, Cheng Li, Cheng Li, Cheng Li, Cheng Li

“…CKD burden varied by region and age, with notable gender disparities.ConclusionThe study highlights a dramatic rise in CKD burden linked to population growth and aging, emphasizing the need for targeted treatment and effective global healthcare policies.…”
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Efficacy of Bacillus clausii UBBC-07 in the prevention of antibiotic-associated diarrhea in children by H.V. Beketova, O.O. Koiro, S.S. Bohdanova, M.S. Bulhakova, K.M. Heorhitsa, O.B. Il’kiv, О.R. Kavka, О.Z. Kmit’, О.V. Kukhar, V.І. Liubetska, V.V. Maleiko, І.А. Matiukhina, К.О. Medvedska, N.B. Pavchak, К.А. Percheklii, V.V. Semenchuk, Y.О. Sotnichenko, U.М. Tomashiuk, N.І. Tsvynda, М.Y. Shalimanova

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Study protocol for key interventions to improve the follow-up adherence postcervical precancerous lesion treatment in Ethiopia: a pragmatic randomised controlled trial by Adamu Addissie, Eva Johanna Kantelhardt, Eric Sven Kroeber, Sefonias Getachew, Muluken Gizaw, Abel Shita, Alemnew Destaw, Eyerusalem Getachew, Miresa Midaksa, Sophie Rossner

“…Thus, the objective of this study is to evaluate key interventions to improve the follow-up adherence rate among women treated for suspicious cervical lesions in primary healthcare settings in Ethiopia.Method and analysis We will employ a pragmatic randomised control trial study design, using Consolidated Standards of Reporting Trials guidelines for reporting and a Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) checklist for developing the protocol, to evaluate intervention effectiveness. …”
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The effect of interactive learning methods and reflection on nurses’ learning in patient safety at the ICU and Emergency department by Samaneh Mirzaei, Fatemeh Keshmiri, Roohangiz Norouzinia, Najmeh Mirjalili, Naeimeh Baghshahi, Mohsen Gholinataj Jelodar

“…Therefore, it should be a priority in every healthcare system worldwide. As the importance of patient safety is increasingly recognized, the emphasis on training and its impact on safety competencies and quality of care has also grown. …”
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Observational study on the current status of thalassaemia in Malaysia: a report from the Malaysian Thalassaemia Registry by Hishamshah Mohd Ibrahim, Zulaiha Muda, Ida Shahnaz Othman, Mohamed Najib Mohamed Unni, Kok Hoi Teh, Asohan Thevarajah, Kogilavani Gunasagaran, Gek Bee Ong, Seoh Leng Yeoh, Aisyah Muhammad Rivai, Che Hadibiah Che Mohd Razali, Nazzlin Dizana Din, Zarina Abdul Latiff, Rahman Jamal, Norsarwany Mohamad, Hany Mohd Ariffin, Hamidah Alias

“…However, cardiac complications are still the main cause of death in patients with thalassaemia.Conclusion Data gathered into the registry can be used to understand the progression of the disorder, to monitor iron overload management and to improve the outcomes of treatment, to enhance preventive strategies, reduce healthcare burden and improve the quality of life. Sustainability of the Malaysian Thalassaemia Registry is important for surveillance of thalassaemia management in the country and help the national health authorities to develop more effective policies.…”
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Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus by Maria Sultan, Maria Razzaq, Joohyun Lee, Shreyasi Das, Shrute Kannappan, Vinod Kumar Subramani, Wanki Yoo, Truc Kim, Hye-Ra Lee, Akhilesh K. Chaurasia, Kyeong Kyu Kim

“…Abstract Background The rapid emergence of multiple drug-resistant (MDR) bacterial pathogens and the lack of a novel antibiotic pipeline pose a serious threat to global healthcare. The limited number of established targets further restricts the identification of novel antibiotics to treat life-threatening MDR infections caused by Staphylococcus aureus strains. …”
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Optimising Xpert-Ultra and culture testing to reliably measure tuberculosis prevalence in the community: findings from surveys in Zambia and South Africa by Richard Hayes, Sarah Fidler, Sian Floyd, María Rupérez, Helen Ayles, Redwaan Vermaak, Kwame Shanaube, Albertus Schaap, Eveline Klinkenberg, Petra de Haas, Barry Kosloff, Thomas Gachie, Pete J Dodd, Chali Wapamesa, Michael J Burnett, Nico Kalisvaart, Tila Mainga, Linda Mureithi

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Inpatient dialectical behavior therapy combined with trauma-focused therapy for PTSD and borderline personality disorder symptoms: study design of the naturalistic trauma therapy s... by Annemieke C. Kamstra, Annemieke C. Kamstra, Sybolt O. de Vries, Maarten F. Brilman, Petty Vasilev, Manna A. Alma, Antoinette D. I. van Asselt, Antoinette D. I. van Asselt, Mia De Wolf, Robert A. Schoevers, Frederike Jörg

“…Secondary outcomes are social functioning, quality of life, borderline and cluster C personality disorder symptoms as treatment predictors, treatment trajectories, clients’ experiences and health economic consequences.MethodsThe naturalistic, longitudinal Trauma Therapy Study is conducted from January 2019 until May 2025 in a mental healthcare center in the Netherlands. Clients with severe PTSD and comorbid conditions who are referred to inpatient DBT-PTSD are included into the study. …”
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