Antimicrobial Activity and Mode of Action of N-Heterocyclic Carbene Silver(I) Complexes by Giusy Castagliuolo, Michela Di Napoli, Tshering Zangmo, Joanna Szpunar, Luisa Ronga, Anna Zanfardino, Mario Varcamonti, Diego Tesauro

“…Silver drugs have played a vital role in human healthcare for the treatment of infections for many centuries. …”
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Trends in palliative care utilization among older adult decedents with and without cancer in Taiwan: a population-based comparative studyResearch in context by Yu-Tai Lo, Tzu-Jung Chuang, Yu-Tung Huang, Yi-Lin Wu, Yi-Ching Yang, Chung-Yi Li

“…Methods: The study utilized data from the Health and Welfare Data Science Center in Taiwan, covering demographic and healthcare variables for 588,010 decedents aged 65+ years who died between 2010 and 2020. …”
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Intratumoral and peritumoral radiomics using multi-phase contrast-enhanced CT for diagnosis of renal oncocytoma and chromophobe renal cell carcinoma: a multicenter retrospective st... by Yongsong Ye, Bei Weng, Yan Guo, Lesheng Huang, Shanghuang Xie, Guimian Zhong, Wenhui Feng, Wenxiang Lin, Zhixuan Song, Huanjun Wang, Tianzhu Liu

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Prevalence of intestinal parasites and Helicobacter pylori co-infection in people with gastrointestinal symptoms in Africa: a systematic review and meta-analysis by Yenesew Mihret Wondmagegn, Getu Girmay, Gashaw Azanaw Amare, Muluneh Assefa, Mebratu Tamir, Zufan Yiheyis Abriham, Abebaw Setegn

“…Abstract Background Gastrointestinal infections caused by intestinal parasites and Helicobacter pylori are significant public health issues in Africa, where poor sanitation and limited access to healthcare contribute to high disease burden. Since there was no previous pooled data regarding the intestinal parasites and Helicobacter pylori co-infections among gastrointestinal symptomatic patients in the African context, this review aimed to determine the overall prevalence of intestinal parasites and Helicobacter pylori co-infection in people with gastrointestinal symptoms in Africa. …”
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Transforaminal Endoscopic Lumbar Discectomy versus Coblation Nucleoplasty Combined with Collagenase Chemonucleolysis for Lumbar Disc Herniation with Grade I Degenerative Spondyloli... by Yuyu Guo, Liuhu Han, Tingting Li, Bingbing Xu, Penghui Ke, Jun Hu, Rongyi Zhang, Yan Guo, Long Zhao, Likui Wang

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Virulence profile of carbapenem-resistant Klebsiella pneumoniae strains by an in vivo model of Galleria mellonella by María Guembe, Rama Hafian, Marta Díaz-Navarro, Andrés Visedo, Flavio De Maio, Fulvia Pimpinelli, Ilaria Cavallo, Mauro Truglio, Francesca Sivori, Enea Gino Di Domenico

“…ABSTRACT Klebsiella pneumoniae is a significant healthcare-associated pathogen, notable for its diverse virulence and antibiotic resistance profiles. …”
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Atopic Dermatitis Treatments Before and After Initiation of Ruxolitinib Cream: 6-Month Follow-Up Analysis of a US Payer Claims Database by Liu J, Desai K, Teng CC, Sturm D, Stockbower G, Patadia H, Willey V

“…This analysis describes treatment patterns before and after initiation of ruxolitinib cream among patients with AD.Patients and Methods: This retrospective, observational study used medical and pharmacy claims data from the Healthcare Integrated Research Database (HIRD®) and included adults and adolescents (aged ≥ 12 years) with an AD diagnosis, a first claim for ruxolitinib cream (index date) between October 2021 and July 2022, and continuous enrollment in a commercial or managed Medicare plan for 6 months before and after the index date. …”
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Optimizing Neurobehavioral Assessment for Patients with Disorders of Consciousness: Proposal of a Comprehensive Pre-Assessment Checklist for Clinicians by Kristen Keech, Caroline Schnakers, Brooke Murtaugh, Katherine O’Brien, Beth Slomine, Marie-Michèle Briand, Rita Formisano, Aurore Thibaut, Anna Estraneo, Enrique Noé, Olivia Gosseries, Liliana da Conceição Teixeira

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A Pragmatic Clinical Trial to Compare the Real-World Effectiveness of V-Go versus Standard Delivery of Insulin in Patients with Advanced Type 2 Diabetes by Mark J. Cziraky, Scott Abbott, Matt Nguyen, Kay Larholt, Elizabeth Apgar, Thomas Wasser, Poul Strange, Leon Shi, H. Courtenay Harrison, Beverly Everitt, Lynn Nowak

“…**Background:** Many patients with type 2 diabetes mellitus (T2DM) do not have adequate glycemic control, leading to poor patient outcomes and high healthcare costs. **Objective:** This prospective pragmatic clinical trial evaluated V-Go, a wearable insulin delivery device, compared with standard treatment optimization (STO) among insulin-treated patients with T2DM in a realworld, community-based practice setting. …”
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Enhancing Semi-Supervised Learning With Concept Drift Detection and Self-Training: A Study on Classifier Diversity and Performance by Jose L. M. Perez, Roberto S. M. Barros, Silas G. T. C. Santos

“…Machine learning algorithms that assist in decision-making are becoming crucial in several areas, such as healthcare, finance, marketing, etc. Algorithms exposed to a larger and more relevant amount of training data tend to perform better. …”
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Geographical Differences in the Safety and Efficacy of Tofacitinib Versus TNFi: A Post Hoc Analysis of ORAL Surveillance by Bogdan Batko, Slawomir Jeka, Piotr Wiland, Agnieszka Zielińska, Maria Stopińska-Polaszewska, Marcin Stajszczyk, Magdalena Kosydar-Piechna, Mary Jane Cadatal, Jose L. Rivas

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Understanding HIV care providers’ support for tobacco cessation among people living with HIV in Western Kenya: a formative qualitative study by Peter Magati, Maya Vijayaraghavan, Elizabeth A Bukusi, Craig R Cohen, Starley B Shade, Zachary Arochi Kwena, Linet Ongeri, Francesca A Odhiambo, Cirilus O Ogala, Yvonne A Olando, Greshon Rota, Purba Chatterjee, Christine A Osula, Jerry J Nutor, Stella S Bialous

“…Introduction Healthcare providers are required to support people living with HIV (PLHIV) to quit tobacco use for improved health outcomes, but it is unclear to what extent they adhere to these requirements. …”
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Glaucoma laser treatments: modern approaches and practice guidelines by M.H. Rabadanova, Zh.G. Oganezova, E.A. Egorov, D.V. Katz, V.V. Novoderezhkin

“…Filatov, Moscow, Russian Federation </p> <p> ³Research Center for Medical Genetics, Moscow, Russian Federation </p> <p> Glaucoma represents a significant medical, economical, and social burden for the healthcare system both in Russia and worldwide. Despite a variety of pharmacological, surgical and laser treatment options, the number of patients with irreversible glaucomatous damage to visual function is continuously rising. …”
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Prevalence and characteristics of gastrointestinal disorders, medication use, and diagnostic interventions in pediatric patients with cystic fibrosis: a nested case–control analysi... by Carolena Trocchia, Carolena Trocchia, Maua Mosha, Bailey Hamner, Neil Goldenberg, Racha Khalaf

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Cost–utility and budget impact analysis of tocilizumab for the treatment of refractory systemic juvenile idiopathic arthritis in Thailand by Nitichen Kittiratchakool, Disorn Kulpokin, Chonticha Chanjam, Soamarat Vilaiyuk, Sirirat Charuvanij, Gun Phongsamart, Parichat Khaosut, Manasita Tanya, Ratanavadee Nanagara, Sira Nantapaisarn, Pattara Leelahavarong

“…Therefore, the price of tocilizumab should be negotiated to reduce the financial impact on the healthcare system.…”
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Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study by Sintayehu Simie Tsega, Yilkal Abebaw Wassie, Alebachew Ferede Zegeye, Mekdes Kiflu, Sisay Maru Wubante, Kennean Mekonnen, Birhaneslasie Gebeyehu Yazew, Birye Dessalegn Mekonnen, Yeshambel Andargie Tarekegn

“…Conclusions This study revealed that the magnitude of depressive symptom among epilepsy patients in Ethiopia was relatively high and multiple factors determined the likelihood of depressive symptom. Thus, healthcare providers and concerned stakeholders should strengthen comprehensive health education to reduce the magnitude and consequences of depressive symptom among this segment of the population. …”
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Cohort profile: Oxford Pain, Activity and Lifestyle (OPAL) Study, a prospective cohort study of older adults in England by Sarah E Lamb, Christian D Mallen, M Watson, Julie Bruce, S Dutton, S Petrou, Lesley Ward, Maria T Sanchez Santos, Esther Williamson, Angela Garrett, Alana Morris, O Conway, F Darton, D Hagan, D Haywood, A Hewitt, I Marian, L Nevay, P Nicolson, M Slark, K Vadher, E Williamson, N Arden, K Barker, G Collins, J Fairbank, J Fitch, D French, F Griffiths, Z Hanson, C Hutchinson

“…The majority of participants (n=5367) also consented for research team to access their UK National Health Service (NHS) Digital and primary healthcare records.Findings to date Mean participant age was 74.9 years (range 65–100); 51.5% (n=2784/5409) were women. 94.9% of participants were white, and 28.8% lived alone. …”
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A systematic review of impact of person-centred interventions for serious physical illness in terms of outcomes and costs by Richard Harding, Sridhar Venkatapuram, Alessandra Giusti, Ruwayda Petrus, Liz Gwyther, Lindsay Farrant, I Petersen, Amelia Cook, Kennedy Bashan Nkhoma

“…Background Person-centred care (PCC) is being internationally recognised as a critical attribute of high-quality healthcare. The International Alliance of Patients Organisations defines PCC as care that is focused and organised around people, rather than disease. …”
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Predicting positive Clostridioides difficile test results using large-scale longitudinal data of demographics and medication history by Anh Pham, Robert El-Kareh, Frank Myers, Lucila Ohno-Machado, Tsung-Ting Kuo

“…Background: Clostridioides difficile infection is a major health threat. Healthcare institutions have strong medical and financial incentives to keep infections under control. …”
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Social determinants of financial stress and association with psychological distress among young adults 18–26 years in the United States by Anaiya Nasir, Umair Javed, Kobina Hagan, Ryan Chang, Harun Kundi, Zahir Amin, Sara Butt, Sadeer Al-Kindi, Sadeer Al-Kindi, Zulqarnain Javed, Zulqarnain Javed

“…FS was assessed as an aggregate score (6–24) based on worry about six life tasks: paying for: monthly bills, housing expenses, healthcare, illness/accident, maintaining standard of living, saving money for retirement. …”
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