Medication underuse in real-life practice: the impact of galcanezumab towards achieving very low frequency episodic migraine in a southeast Asian middle-income nation by Wanakorn Rattanawong, Prakit Anukoolwittaya, Akarin Hiransuthikul, Thanakit Pongpitakmetha, Auranee Trisataya, Sekh Thanprasertsuk, Alan Rapoport

“…Abstract Background Migraine progression, particularly from episodic to chronic migraine (CM), increases disease burden and healthcare costs. Understanding the new concept of “Medication Underuse Headache” should encourage the health care provider to consider early intervention with calcitonin gene-related peptide (CGRP) monoclonal antibodies. …”
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Establishment of a prognostic signature and immune infiltration characteristics for uterine corpus endometrial carcinoma based on a disulfidptosis/ferroptosis-associated signature by Yong Huang, Huibin Li, Zhifu Wei, Wanshan He, Bin Chen, Shuang Cheng, Zhifang Zhao, Lv Deng, Lv Deng, Xiaohua Chen, Yu Lin, Yu Lin, Xiaoshan Hong, Xiaoshan Hong

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Neuroprotective Efficacy of <i>Astragalus mongholicus</i> in Ischemic Stroke: Antioxidant and Anti-Inflammatory Mechanisms by Yongjae Hong, Geon Ko, Yeong-Jae Jeon, Hyeon-Man Baek, Juni Lee, Donghun Lee, Jieun Park, Jaehong Kim, Keun-A Chang

“…Stroke affects over 12 million people annually, leading to high mortality, long-term disability, and substantial healthcare costs. Although East Asian herbal medicines are widely used for stroke treatment, the pathways of operation they use remain poorly understood. …”
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Challenges in diagnosing polyethylene glycol and polysorbate 80 allergies: implications for allergic reactions in COVID-19 mRNA vaccination program: experience from Qatar by Sami Aqel, Sherin Thalappil, Asaad Imameldin, Dalal Mudawi, Muna Al Maslamani, Abdullatif Al-Khal, Hassan Mobayed, Maryam Ali Al-Nesf, Tayseer Ibrahim

“…IntroductionCOVID-19 vaccination has been a key intervention in reducing the severity of symptoms; however, concerns about vaccine safety, particularly regarding allergic reactions, arose early on. Healthcare workers faced the challenge of addressing these concerns to ensure safe vaccine administration. …”
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AI-optimized electrochemical aptasensors for stable, reproducible detection of neurodegenerative diseases, cancer, and coronavirus by Amira Elsir Tayfour Ahmed, Th.S. Dhahi, Tahani A. Attia, Fawzia Awad Elhassan Ali, Mohamed Elshaikh Elobaid, Tijjani Adam, Subash C.B. Gopinath

“…Despite a higher cost ($500-$1,500/unit), their enhanced portability and diagnostic performance promise to revolutionize healthcare, environmental monitoring, and food safety, ultimately improving public health outcomes.…”
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Predictive Value of Lung Ultrasound Scores Combined with Serum ANGPTL4 Levels on Severity and Prognosis of Neonatal Respiratory Distress Syndrome by Wang L, Ji P, Yin J, Xue M, Wang J, Wan Y, Dong B

“…Liangfu Wang,1 Ping Ji,2 Jiansong Yin,2 Mei Xue,2 Jing Wang,3 Yu Wan,2 Baoqiang Dong4 1Department of Soft Traumatology of Integrated Chinese and Western Medicine, Shenyang Fourth People’s Hospital, Shenyang, Liaoning, 110031, People’s Republic of China; 2Neonatal Intensive Care Unit, Second People’s Hospital of Changzhou Affiliated to Nanjing Medical University, Changzhou, Jiangsu, 213164, People’s Republic of China; 3Department of Child Healthcare, Second People’s Hospital Changzhou Affiliated to Nanjing Medical University, Changzhou, Jiangsu, 213164, People’s Republic of China; 4College of Acupuncture and Massage, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, 110000, People’s Republic of ChinaCorrespondence: Baoqiang Dong, College of Acupuncture and Massage, Liaoning University of Traditional Chinese Medicine, No. 77 Chongshan East Road, Huanggu District, Shenyang, Liaoning, 110000, People’s Republic of China, Tel +86-024-31207001, Email DongBaoqiang3071@163.comObjective: Respiratory distress syndrome threatens neonates’ life. …”
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Budget Impact of Rivaroxaban for the Prevention of Thromboembolic Events after Hip or Knee Replacement in Spain by Xavier Granero Xiberta, Antonio Murcia, José Ricardo Troncoso Durán, Claudio Gómez Zubeldia, Aleix Llorac Moix, Ruth Graefenhain De Codes, Maria Giovana Ferrario, Luis Lizán

“…Health care resources including pharmacologic prophylaxis, anesthesia and nurse care costs (Euros 2014) were estimated from the Spanish National Healthcare System (NHS) perspective. The annual cost associated with each cohort was estimated based on the mean cost per patient and the estimated distribution of use of rivaroxaban or enoxaparin in the base case scenario and alternative scenario (increase of rivaroxaban use) over the 3 years. …”
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Economic evaluation of a randomized controlled trial comparing mifepristone and misoprostol with misoprostol alone in the treatment of early pregnancy loss. by Charlotte C Hamel, Marcus P L M Snijders, Sjors F P J Coppus, Frank P H A Vandenbussche, Didi D M Braat, Eddy M M Adang

“…<h4>Methods and findings</h4>A cost-effectiveness analysis (CEA) from a healthcare perspective was performed alongside a randomised controlled trial (RCT) in which standard treatment with misoprostol only was compared with a combination of mifepristone and misoprostol, in women with EPL after a minimum of one week of unsuccessful management. …”
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Reducing medical cannabis use risk among Veterans: A descriptive study by Laura M. Harris-Lane, Mitchell Sheehy, Courtney A. Loveless, Joshua A. Rash, David P. Storey, Gregory K. Tippin, Vikas Parihar, Nick Harris

“…Almost half of all Veterans received their cannabis information from a healthcare provider or the internet. Conclusions Our study suggests the importance of safer use guidelines tailored for MC use. …”
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Use of Texture Analysis on Noncontrast MRI in Classification of Early Stage of Liver Fibrosis by Ru Zhao, Xi-Jun Gong, Ya-Qiong Ge, Hong Zhao, Long-Sheng Wang, Hong-Zhen Yu, Bin Liu

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Time to dietary diversity of complementary feeding improvements and its associated factors among infants aged 6–12 months in Ethiopia: evidence from performance monitoring for acti... by Feyisa Shasho Bayisa, Teshome Demis Nimani, Samuel Demissie Darcho, Abainash Tekola

“…It suggests that public health interventions should focus on enhancing maternal knowledge and promoting regular healthcare visits to mitigate malnutrition and improve infant health outcomes in Ethiopia.…”
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Design and psychometric testing of a moral intelligence instrument for pre-hospital emergency medical services personnel: a sequential-exploratory mixed-method study by Fateme Mohammadi, Rasoul Salimi, Salman Khazaei, Mostafa Bijani

“…Conclusion The Moral Intelligence Scale for prehospital EMS personnel demonstrated acceptable psychometric properties. Consequently, healthcare administrators may employ this instrument to assess moral intelligence in prehospital EMS personnel. …”
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Global variation in the assessment of psychological trauma in pregnancy by Kathryn Wall, Francesca Penner, Lindsey Wallace Goldman, Jin Young Shin, Eloise Novak, Amanda Lowell, Michèle Day, Lea Papa, Drew Wright, Soudabeh Givrad, Helena J. V. Rutherford

“…We found that most studies measuring psychological trauma in pregnancy across the nine geopolitical regions assessed interpersonal trauma, and the fewest number of studies assessed healthcare trauma. Moreover, for each type of psychological trauma assessed, the greatest number of studies was conducted in North America. …”
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Assessment of nurses’ knowledge and practice of pressure injuries prevention for critically ill patients in Rwanda: a cross-sectional study by Sophie Mukantwari, Emmanuel Bikorimana, Liberatha Rumagihwa, Ime U. Akaninyene, Christian Ntakirutimana, Joseph Mucumbitsi, Thierry Claudien Uhawenimana, David Ikwuka

“…A 33-item instrument drawn from pressure ulcer risk assessment and prevention toolkits established by the Agency for Healthcare Research and Quality was used to assess nurses’ practices. …”
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F-FDG PET/CT Quantitative Parameters and Texture Analysis Effectively Differentiate Endometrial Precancerous Lesion and Early-Stage Carcinoma by Tong Wang MD, Hongzan Sun MD, Yan Guo PhD, Lue Zou MD

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Tissue Doppler echocardiography predicts long-term cardiovascular mortality: the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) legacy 20-year follow-up study by Simon Thom, Alice Stanton, Jamil Mayet, Amit Kaura, Darrel Francis, Anoop SV Shah, Andrew Sharp, Alun D Hughes, Neil R Poulter, Anenta Ratneswaren, Tong Wu, Somayeh Rostamian, Devan Wasan, PS Sever

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Affective valence predictors from real-world based short sprint interval training by Stefano Benítez-Flores, Flávio A. de S. Castro, Eduardo Caldas Costa, Daniel Boullosa, Todd A. Astorino

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A new health literacy scale for staff in preschool childcare institution: development and preliminary validation by Xinqi Zhuang, Yitong Jia, Tianxin Cui, Ge Meng, Jianzhong Zhang, Linxia He, Yin-Ping Zhang

“…Abstract Background The health literacy of staff in preschool childcare institution is an important issue to consider in providing healthcare for children aged 3–6 years, which could contribute to reducing incidence of diseases and accidental injuries as well as maintaining children’s good health. …”
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Perioperative SARS-CoV-2 Infection in Patients Undergoing Elective Surgery in Gynecology Clinic: Tertiary Center Experience by Gulnihal Reyhan Toptas, Eylem Unlubilgin, Tugba Kinay, Ali Riza Dogan, Mehmet Akif Akgul, Sitare Aslanova, Emel Ebru Ercan, Vakkas Korkmaz, Sezin Erturk Aksakal, Yaprak Ustun

“…CONCLUSION: The results of our study show that gynecological surgical procedures do not increase the transmission and mortality rates of SARS-CoV-2 among patients and healthcare professionals as long as infection control measures are followed. …”
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Estimated inpatient malnutrition prevalence, screening tool utilization, and dietitian referral rates across hospitals during extension of phase 2 of More-2-Eat by Yingying Xu, Rachel A. Warren, Shirley M. Peters, Sonya Boudreau, Tina N. Strickland, Mari Somerville, Brenda L. MacDonald, Heather Keller, Leah E. Cahill

“…Summary: Background &amp; Aims: Malnutrition is associated with increased hospital length of stay, disease burden, and healthcare costs. The Integrated Nutrition Pathway for Acute Care (INPAC) is a validated multi-step algorithm that includes screening using the Canadian Nutrition Screening Tool (CNST) and diagnosis using Subjective Global Assessment (SGA). …”
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