Economic and Humanistic Burden of Moderate and Severe Hemophilia A and B in Spain: Real-World Evidence Insights from the CHESS II Study by Carmen Peral, Alfonso De Lossada Juste, Nadia Lwoff, Nataly Espinoza-Cámac, Miguel Ángel Casado, Tom Burke, Jose Alvir, Sheena Thakkar, Enrico Ferri Grazzi

“…**Methods:** Spanish data from the CHESS II study (2018-2020) on patients' clinical characteristics, health-related quality of life (HRQoL) and hemophilia-related healthcare resource utilization were analyzed. Economic burden was determined by estimating condition-related annual per-patient direct (medical and nonmedical) and indirect costs, stratified according to hemophilia type and severity and presented as 2022 Euros. …”
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Evaluation of Safety and Efficacy of a Single Lorecivivint Injection in Patients with Knee Osteoarthritis: A Multicenter, Observational Extension Trial by Christopher J. Swearingen, Jeyanesh R. S. Tambiah, Ismail Simsek, Heli Ghandehari, Sarah Kennedy, Yusuf Yazici

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The relationship between college students’ Suicidal ideation and rejection sensitivity: a network analysis by Yang He, Tianqi Yang, Chunyan He, Yuanbei Zhang, Huilin Yang, Shen Huang, Jianjun Liu, Xihong Li, Tao Xu, Shengjun Wu

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Prevalence and characteristics of HPV vaccine hesitancy among parents of adolescent females across Saudi Arabia by Sahar Othman, Ranya Ghamri, Wala Alhamadah, Anwaar Alsatty, Dhuha Khesfaty, Ohoud Alghamdi, Ragad Arbaein, Alaa M. Baglagel, Jumana Khayyat, Bushra Almalki

“…In addition, lack of recommendation by their healthcare provider and inconvenience related to immunization with the vaccine were also associated with higher levels of hesitancy.ConclusionHPV vaccine hesitancy remains high among parents of adolescent females in Saudi Arabia. …”
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Family caregiver frailty in adult congenital heart disease is overlooked: A call to action by Arianna Magon, Serena Francesca Flocco, Laura Schianchi, Massimo Chessa, Daniele Ciofi, Salvatore Angileri, Maddalena De Maria, Gianluca Conte, Silvia Favilli, Cristina Arrigoni, Rosario Caruso

“…The frailty of family caregivers (FCs) of adults with congenital heart disease (CHD) is an underrecognized yet critical issue in healthcare. As individuals with CHD live longer, their FCs, often aging alongside them, face escalating physical, emotional, and psychological challenges. …”
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Gut Microbiota and Its Impact on Brain Function and Mental Health by Zofia Martyna Wójcik, Katarzyna Kamińska-Omasta, Bartosz Omasta, Olga Krupa, Paulina Dorota Pietrukaniec, Kuba Borys Romańczuk, Kinga Furtak, Szymon Przemysław Stolarczyk, Magdalena Agata Czerska, Daria Rybak

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The Impact of Migraine on the Whole Life Course of Patients: Results from the OVERCOME (Japan) 2nd Study by Daisuke Danno, Shiho Suzuki, Tsubasa Takizawa, Ryotaro Ishii, Masayuki Hamakawa, Yoshinori Tanizawa, Satoshi Osaga, Mika Komori

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Helicobacter pylori infection diagnostics and choice of eradication treatment: results of inquiry of doctors from different regions of Russian Federation by N. N. Dekhnich, R. S. Kozlov, O. A. Sablin, Ye. A. Prischepova

“…Overall 261 doctors of healthcare institutions in 15 cities of Russia (Orel, St. …”
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“A one-stop shop”: Real-world use and app-users' experiences of a psychoeducational smartphone app for adults with ADHD by Christina Seery, Rachel Hannah Cochrane, Martha Mulcahy, Ken Kilbride, Margo Wrigley, Jessica Bramham

“…Digital health tools created by public health organisations should consider how people's previous experiences with healthcare services can impact how they perceive the information in the tools.…”
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IoT-Based Multisensors Fusion for Activity Recognition via Key Features and Hybrid Transfer Learning by Ahmad Jalal, Danyal Khan, Touseef Sadiq, Moneerah Alotaibi, Sultan Refa Alotaibi, Hanan Aljuaid, Hameedur Rahman

“…Human activity recognition (HAR) has attracted significant attention in various fields, including healthcare, smart homes, and human-computer interaction. …”
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Human and entomological determinants of malaria transmission in the Lihir Islands of Papua New Guinea: A cross-sectional study. by Pere Millat-Martínez, Michelle Katusele, Bernadine Kasian, Elias Omera, Esther Jamea, Lina Lorry, Aina Casellas, Dan Ouchi, Chilaka Wali, Sylvia Raulo, Arthur Elizah, Peter Kaman, Absalom Dau, Muker Sakur, Lemen Kilepak, Siub Yabu, Nelson Koata, John Kave, Michael Toa, Christopher Urakusie, Charles Kongs, Frank Kisba, Moses Laman, Oriol Mitjà, William Pomat, Quique Bassat, Stephan Karl, Bàrbara Baro

“…Measures focusing on at-risk groups, including vector-control and transmission interruption methods, could be taken into account by the mine and the healthcare authorities to reduce malaria burden outside the MIZ.…”
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Exploring Acute Kidney Injury Incidence in Hip Periprosthetic Joint Infection Treatment With Combined Intravenous and Intra-articular Antibiotic Infusion by Wenbo Mu, MD, PhD, Boyong Xu, MD, Fei Wang, MD, Wentao Guo, MD, PhD, Xiaogang Zhang, MD, Li Cao, MD

“…Background: Periprosthetic joint infections (PJIs) are a significant complication following total hip arthroplasty, impacting patient health and healthcare costs. This study examines the incidence of acute kidney injury (AKI) in patients undergoing hip PJI treatment with a combination of intravenous and intra-articular antibiotic infusion therapies. …”
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Diagnostic Performance of Deep Learning Applications in Hepatocellular Carcinoma Detection Using Computed Tomography Imaging by Enes Şahin, Ozan Can Tatar, Mehmet Eşref Ulutaş, Sertaç Ata Güler, Turgay Şimşek, Nihat Zafer Utkan, Nuh Zafer Cantürk

“…As artificial intelligence technology continues to evolve, its integration into healthcare systems is expected to advance the accuracy and efficiency of diagnostics in oncology, enhancing early detection and treatment strategies and potentially improving patient survival rates.…”
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Clinical Characteristics and Prevalence of Comorbidities according to Metformin Use in Korean Patients with Type 2 Diabetes by Sang Ouk Chin, In Gyoon Ha, Sang Youl Rhee, Su Jin Jeong, Suk Chon, Sung Hoon Kim, Kyu Jeung Ahn, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Jeong Taek Woo

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Work-Related Musculoskeletal Disorders and Associated Factors Among Bankers in Ethiopia, 2018 by Alemu Kasaw Kibret, Berihu Fisseha Gebremeskel, Kebede Embaye Gezae, Gebrerufael Solomon Tsegay

“…WMSDs are the major causes of disability and cause individual suffering and financial burdens to the individual, families, industry or employer, healthcare system, and society at large. This study aims to assess the prevalence and associated factors of work-related musculoskeletal disorders among bankers working in Mekelle city, Tigray, Ethiopia, 2018. …”
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Safety and Efficacy of Hydroxypropyl Guar-Hyaluronic Acid Dual-Polymer Lubricating Eye Drops in Indian Subjects with Dry Eye: A Phase IV Study by Deborah Awisi-Gyau, Neha Kapur, Rajesh Parekh, Umesh Yeddula, Shreesha Kumar Kodavoor

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Swiss chiropractic practice-based research network and musculoskeletal pain cohort pilot study: protocol of a nationwide resource to advance musculoskeletal health services researc... by Milo A Puhan, Viktor von Wyl, Alice Kongsted, Cesar A Hincapié, Léonie Hofstetter, Rahim Lalji

“…A nationwide Swiss chiropractic practice-based research network (PBRN) and MSK pain patient cohort study will have potential to monitor the epidemiological trends of MSK pain conditions and contribute to healthcare quality improvement. The primary aims of this protocol are to (1) describe the development of an MSK-focused PBRN within the Swiss chiropractic setting, and (2) describe the methodology of the first nested study to be conducted within the PBRN—an observational prospective patient cohort pilot study.Methods and analysis This initiative is conceptualised with two distinct phases. …”
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Prevalence of Undernutrition and Associated Factors among Pregnant Women in a Public General Hospital, Tigray, Northern Ethiopia: A Cross-Sectional Study Design by Ebud Ayele, Guesh Gebreayezgi, Teklewoini Mariye, Degena Bahrey, Gebrekiros Aregawi, Gebregziabher Kidanemariam

“…In this study, occupation, history of having malaria during pregnancy, wanted type pregnancy, coffee intake during pregnancy, and hemoglobin < 11 g/dl were factors significantly associated with undernutrition in pregnant mothers. So, healthcare providers, policymakers, and other stakeholders should give special focus on these factors.…”
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Impact of introducing transnasal endoscopy on expanding diagnostic endoscopy services by Nigel Trudgill, Hasan Haboubi, Jeff Turner, Laura Munglani, Tom Crosby, Ben Thomas Crosby, Karen Wright, Kay Charles, Wendy Evans, Megan Mathias, Stevie Davies, Badr Abdalla

“…TNE also shows promise in correcting misdiagnoses of short-segment Barrett’s oesophagus (39%) compared with TOE (14.8%) (p=0.087).Conclusion TNE is an emerging endoscopic modality, which shows great promise in replacing TOE in most diagnostic circumstances. In a modern healthcare service, TNE is cheaper, better tolerated and outperforms TOE in multiple domains.…”
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Investigating the implementation of a Trial of Labour After Caesarean (TOLAC) delivery bundle with respect to decreasing caesarean delivery rates: a multisite quality improvement i... by Eliane M Shore, Elizabeth Miazga, Cheyanne Reed, Alisha Olsthoorn, Isabella Fan, Eliya Zhao, Jodi Shapiro, Amanda Cipolla, Modupe Tunde-Byass

“…Objectives To study the effect of implementing a Trial of Labour After Caesarean (TOLAC) delivery bundle with respect to decreasing caesarean delivery rates across five hospitals.Design Prospective quality improvement study.Setting Five Canadian hospital sites participated, two academic centres and three community hospitals, with annual delivery rates ranging from 2500 to 7500 per site.Participants All obstetrical patients with a singleton gestation in cephalic presentation and only one previous caesarean delivery were included.Interventions A TOLAC bundle was introduced at each hospital site, consisting of three main interventions: (1) education for healthcare providers, (2) a TOLAC discussion sheet and (3) patient educational tools.Primary and secondary outcome measures The primary outcome was the caesarean delivery rate in eligible patients. …”
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