Vitamin D Status and VDR Genotype in NF1 Patients: A Case-Control Study from Southern Brazil by Larissa Souza Mario Bueno, Clévia Rosset, Ernestina Aguiar, Fernando de Souza Pereira, Patrícia Izetti Ribeiro, Rosana Scalco, Camila Matzenbacher Bittar, Cristina Brinckmann Oliveira Netto, Guilherme Gischkow Rucatti, José Artur Chies, Suzi Alves Camey, Patricia Ashton-Prolla

“…These polymorphisms are in partial linkage disequilibrium and the haplotype frequencies also did not differ in a significant way between the two groups (p=0.613).…”
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Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Coronary Heart Disease by Jean Dallongeville, Carlos Iribarren, Jean Ferrières, Liisa Lyon, Alun Evans, Alan S. Go, Dominique Arveiler, Stephen P. Fortmann, Pierre Ducimetière, Mark A. Hlatky, Philippe Amouyel, Audrey Southwick, Thomas Quertermous, Aline Meirhaeghe

“…No such association could be detected in ADVANCE. Haplotype distributions were similar in cases and control in both studies. …”
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Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus by Saowanee Chamnanya, Benyapa Kiddela, Jassada Saingamsook, Woottichai Nachaiwieng, Nongkran Lumjuan, Pradya Somboon, Jintana Yanola

“…The kdr L1014F mutation and the haplotype of the CYP9M10 gene were detected in survivor and dead mosquitoes after exposure to the deltamethrin WHO test paper. …”
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A Highly Divergent Mitochondrial Genome in Extant Cape Buffalo From Addo Elephant National Park, South Africa by Deon deJager, Marlo Möller, Eileen Hoal, Paul vanHelden, Brigitte Glanzmann, Cindy Harper, Paulette Bloomer

“…Hluhluwe–iMfolozi Park (n = 15) had low levels of genetic diversity, with only four haplotypes detected, reflecting its past bottleneck. …”
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Response to Infliximab in Crohn’s Disease: Genetic Analysis Supporting Expression Profile by Luz María Medrano, Carlos Taxonera, Cristina González-Artacho, Virginia Pascual, María Gómez-García, Manuel Barreiro-de Acosta, José L. Pérez-Calle, Fernando Bermejo, Antonio López-Sanromán, Dolores Martín Arranz, Javier P. Gisbert, Juan Luis Mendoza, Javier Martín, Concepción Núñez, Elena Urcelay

“…These differences were amplified in patients with colonic and ileocolonic location for all but the TNFAIP6 haplotype, which evidenced significant difference in ileal CD patients. …”
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Novel loci for triglyceride/HDL-C ratio longitudinal change among subjects without T2D by Lihua Wang, Siyu Wang, Jason A. Anema, Vaha A. Moghaddam, Yanli Lu, Shiow Lin, E. Warwick Daw, Allison L. Kuipers, Iva Miljkovic, Michael Brent, Gary J. Patti, Bharat Thygarajan, Joseph M. Zmuda, Michael A. Province, Ping An

“…GWAS used a linear mixed model accounting for familial relatedness. GWLS employed haplotype-based identity-by-descent estimation with 0.5 cM average spacing. …”
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TMEM187-IRAK1 Polymorphisms Associated with Rheumatoid Arthritis Susceptibility in Tunisian and French Female Populations: Influence of Geographic Origin by Olfa Khalifa, Nathalie Balandraud, Nathalie Lambert, Isabelle Auger, Jean Roudier, Audrey Sénéchal, David Geneviève, Christophe Picard, Gérard Lefranc, Isabelle Touitou, Bakridine M’Madi Mrenda, Cécilia Benedito, Etienne Pardoux, Anne-Laure Gagez, Yves-Marie Pers, Christian Jorgensen, Touhami Mahjoub, Florence Apparailly

“…In the French population, the GTC haplotype displayed a protective effect against RA, while the ATC, GCC, and GTT haplotypes conferred significant risk for RA. …”
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High clinical utility of long-read sequencing for precise diagnosis of congenital adrenal hyperplasia in 322 probands by Yunpeng Wang, Gaohui Zhu, Danhua Li, Yu Pan, Rong Li, Ting Zhou, Aiping Mao, Libao Chen, Jing Zhu, Min Zhu

“…Expand to 322 probands, the actual frequency of duplication haplotype (1.55%) could be calculated due to the accurate genotyping. …”
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Altered chromatin landscape and 3D interactions associated with primary constitutional MLH1 epimutations by Paula Climent-Cantó, Marc Subirana-Granés, Mireia Ramos-Rodríguez, Estela Dámaso, Fátima Marín, Covadonga Vara, Beatriz Pérez-González, Helena Raurell, Elisabet Munté, José Luis Soto, Ángel Alonso, GiWon Shin, Hanlee Ji, Megan Hitchins, Gabriel Capellá, Lorenzo Pasquali, Marta Pineda

“…Methods Four carriers of a primary CME and three non-methylated relatives carrying the same genetic haplotype were included. Genetic alterations were sought using linked-read WGS in blood DNA. …”
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Molecular Data Confirm the Occurrence of the Allochthonous <i>Gambusia holbrooki</i> (Pisces: Poeciliidae) in Sicily and the Maltese Archipelago by Luca Vecchioni, Mirko Liuzzo, Arnold Sciberras, Jeffrey Sciberras, Justin Formosa, Alan Deidun, Gabriele Giacalone, Vincenzo Arizza, Marco Arculeo, Federico Marrone, Francesco Paolo Faraone

“…Based on sequences of the mitochondrial cytochrome b gene, we consistently observed the occurrence of only <i>G. holbrooki</i> in the investigated area, finding, almost exclusively, the most common haplotype known for the species in the whole invaded range (i.e., “HOL1”).…”
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Bees on the run: Nosema spp. (Microsporidia) in Apis mellifera and related products, Italy by Giovanni Sgroi, Luigi Jacopo D’Auria, Luigi Jacopo D’Auria, Maria Gabriella Lucibelli, Andrea Mancusi, Yolande Thérèsa Rose Proroga, Mauro Esposito, Mauro Esposito, Simona Rea, Daniel Signorelli, Federica Gargano, Nicola D’Alessio, Ranju Ravindran Santhakumari Manoj, Peyman Khademi, Giuseppe Rofrano, Giuseppe Rofrano

“…The computation of polymorphisms revealed high haplotype diversity (i.e., Hd = 1.000) and low nucleotide diversity (i.e., Pi = 0.00913) of N. ceranae sequence types.DiscussionThis study reveals a high circulation of N. apis and N. ceranae in Southwestern Italy, indicating the need for improved monitoring of these microsporidia to protect bee welfare and bee industry.…”
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Identification of Genetic Markers of <i>APOM</i> and <i>CYP7A1</i> Genes Affecting Milk Production Traits in Chinese Holstein by Yanan Liu, Zijiao Guo, Junqing Ni, Chendong Yang, Bo Han, Yabin Ma, Jianming Li, Guie Jiang, Weijie Zheng, Dongxiao Sun

“…With Haploview 4.2, we further found that six SNPs in <i>APOM</i> and thee SNPs in <i>CYP7A1</i> formed one haplotype, respectively. The haplotypes were significantly associated with at least one of milk production traits as well (<i>p</i> = <0.01~0.02). …”
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GWAS of CRP response to statins further supports the role of APOE in statin response: A GIST consortium study by Emma F. Magavern, Harshal Deshmukh, Geraldine Asselin, Elizabeth Theusch, Stella Trompet, Xiaohui Li, Raymond Noordam, Y.-D. Ida Chen, Teresa E. Seeman, Kent D. Taylor, Wendy S. Post, Jean-Claude Tardif, Dirk S. Paul, Emelia J. Benjamin, Nancy L. Heard-Costa, Ramachandran S. Vasan, Jerome I. Rotter, Ronald M. Krauss, J.Wouter Jukema, Paul M. Ridker, Patricia B. Munroe, Mark J. Caulfield, Daniel I. Chasman, Marie-Pierre Dubé, Graham A. Hitman, Helen R. Warren

“…The missense lead variant rs429358 at APOE, contributing to the APOE-E4 haplotype, is a risk locus for dyslipidaemia, Alzheimer’s and coronary artery disease (CAD). …”
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MOLECULAR DATING OF INTRASPECIFIC DIFFERENTIATION OF THE STOAT (MUSTELA ERMINEA) BASED ON THE VARIABILITY OF THE MITOCHONDRIAL ND2 GENE by B. A. Malyarchuk, G. A. Denisova, M. V. Derenko

“…Analysis of the data on ND2 variability in stoats presented here and in earlier studies shows that the divergence level between American and Eurasian mtDNA haplotypes is about 5 %, whereas that among Eurasian ones is as low as 0,5 %. …”
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Protocol for reconstructing ancestral genomes from present-day samples by applying local ancestry inference by Xiaoxi Zhang, Baonan Wang, Jia Wen, Yang Gao, Yuwen Pan, Shuhua Xu

“…We describe steps for estimating haplotypes, inferring local ancestry, and assembling ancestral haplotypes. …”
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Diversité des allotypes des immunoglobulines (systèmes Gm et Km) d’une population berbère de la vallée de Tacheddirt (Haut Atlas, Maroc). Comparaison à d’autres populations africai... by Jean-Michel Dugoujon, Olivia Lemaire, Evelyne Guitard, André Sevin, Georges Larrouy, Pedro Moral, Btissam Sabir, Abdellatif Baali, Mohamed Cherkaoui

“…Results show a relative homogeneity of the Berber populations (with about 20 % of sub-Saharan haplotypes). It is interesting to note that in the genetic structure of Touaregs from Algeria (Issequamarenes) there is a higher frequency of sub-Saharan haplotypes.…”
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Identification of Salvia miltiorrhiza germplasm resources based on metabolomics and DNA barcoding by Gaojie He, Jinhui Man, Ying Chen, Xiaoqin Zhang, Xin Wang, Kelu An, Laha Amu, Wenqin Chen, Baowei Wang, Yue Shi, Yue Shi, Xiaohui Wang, Xiaohui Wang, Shengli Wei, Shengli Wei

“…Additionally, comparative chloroplast genome analysis indicated that atpF and rps4-trnT-UGU were the potential DNA barcodes for S. miltiorrhiza. 259 samples from 13 provinces and 21 origins were amplified and sequenced, resulting in the identification of 62 haplotypes. The unique haplotypes found in Shanxi Luoyang, Shandong Qingdao and other places can be used as molecular geographic markers for the identification of the germplasm source of S. miltiorrhiza.DiscussionThis study systematically differentiates S. miltiorrhiza from its adulterants and highlights the potential of unique haplotypes as markers for sourcing. …”
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Genetic Variability of Aspergillus flavus Isolates from a Mississippi Corn Field by Cesar D. Solorzano, Hamed K. Abbas, Robert M. Zablotowicz, Perng-Kuang Chang, Walker A. Jones

“…Variability in the sequence of the omtA gene of the majority of the field isolates (n=118) was compared to strain K49. High levels of haplotypic diversity (24 omtA haplotypes; Hd = 0.61 ± 0.04) were found. …”
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Branchinecta orientalis Sars, 1901 (Anostraca: Branchinectidae) in Onon-Torey lakes of the Trans-Baikal Territory by Petr V. Matafonov, Natalia M. Sukhikh

“…Mitochondrial 12SrRNA and CO1 sequences from Transbaikalia were integrated into the pool of Asian populations of B. orientalis. Both studied CO1 haplotypes turned out to be individual, although at a distance of two or three nucleotide substitutions from one of the most numerous Mongolian-Tibetan haplotypes. …”
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Population Genetic Analysis of Lobelia rhynchopetalum Hemsl. (Campanulaceae) Using DNA Sequences from ITS and Eight Chloroplast DNA Regions by Mulatu Geleta, Tomas Bryngelsson

“…DNA sequence data from the internal transcribed spacer of nuclear ribosomal DNA and eight chloroplast DNA regions were used to investigate haplotypic variation and population genetic structure of the Afroalpine giant lobelia, Lobelia rhynchopetalum. …”
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