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981
Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis
Published 2025-01-01“…Additionally, 16S rRNA sequencing analyzed HRW’s effect on gut microbiota. HRW can significantly improve cognitive impairment and depression-like behavior in zebrafish AD model, reduce Aβ deposition (p < 0.0001), regulate liver Soluble epoxide hydrolase (sEH) levels (p < 0.05), reduce neuroinflammation, and reduce oxidative stress. …”
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982
Studies on the alleviating effect of Bifidobacterium lactis V9 on dextran sodium sulfate-induced colitis in mice
Published 2025-01-01“…V9 increased the abundance of gut microbiota in colitis mice to promote the growth of beneficial bacteria. …”
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983
Effects of environmental bisphenol S exposure on male rat reproductive health and gut-blood-testicular axis integrity
Published 2025-01-01“…These observations were made by counting with a hemocytometer under the optical microscope. 16S rRNA and untargeted metabolomic elucidated potential impacts on the gut-blood-testicular axis: BPS impaired the physical barrier, evoked inflammation, and resulted in dysbiosis of the gut microbiota. Additionally, BPS altered serum metabolites, including phosphatidic acid and diacylglycerol, which are involved in Fc gamma R-mediated phagocytosis and linked to inflammation. …”
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984
Impact of Food Physical Properties on Oral Drug Absorption: A Comprehensive Review
Published 2025-01-01“…The impact of food on drug absorption is complex and multifaceted, potentially involving alterations in gastrointestinal physiology, increases in splanchnic blood flow rates, and shifts in the gut microbiota’s composition. Up to now, extensive research has focused on the interactions between food composition (such as proteins, fats, and vitamins) and drug absorption. …”
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985
Protocol for faecal microbiota transplantation in irritable bowel syndrome: the MISCEAT study – a randomised, double-blind cross-over study using mixed microbiota from healthy dono...
Published 2022-06-01“…Our study will examine the effectiveness of stool transfer with artificially increased microbial diversity in IBS treatment.Methods and analysis A three-group, double-blind,randomised, cross-over, placebo-controlled study of two pairs of gut microbiota transfer will be conducted in 99 patients with diarrhoeal or mixed type of IBS. …”
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986
The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota
Published 2024-12-01“…This suggests that a new gut microbiota profile was selected due to the microalgae inclusion in the provided diet. …”
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987
Are Artificial Sweeteners a Healthier Alternative to Sugar?
Published 2025-02-01“…Some studies suggest possible changes in metabolism or gut microbiota, but evidence is inconclusive. Regulatory bodies like the FDA deem approved sweeteners safe within recommended daily limits. …”
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988
Clinical Study of Limosilactobacillus reuteri for the Treatment of Children with Chronic Tic Disorders/Tourette Syndrome: A Mid-Term Efficacy Evaluation
Published 2024-12-01“…Abstract Introduction Gut microbiota plays an important role in tic disorders (TDs); however, clinical research on probiotics for chronic TDs treatment is lacking. …”
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989
Wet pulverization combined with temperature cycling strategy for extraction of Stropharia rugosoannulata protein with attenuating hepatic steatosis on obese mice
Published 2025-01-01“…Moreover, SRA repaired the cross-talk between gut microbiota and liver via modulating intestinal microecology, and restoring the integrity and function of the intestinal barrier in obese mice. …”
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990
Strawberry dietary intervention influences diversity and increases abundances of SCFA-producing bacteria in healthy elderly people
Published 2025-02-01“…Our findings suggest that a dietary intervention based on strawberries can positively alter the gut microbiota of healthy elderly people as seen in an enrichment of SCFA-producing genera, increased diversity, and a reduction in potentially pathogenic bacteria.IMPORTANCEAging is often associated with changes in the gut microbiome, including a decline in beneficial bacteria and an increase in potentially pathogenic species. …”
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991
The Beneficial Application of Turmeric (Curcuma longa L.) on Health and Egg Production, in Layers: A Review
Published 2024-11-01“…It has also been shown to have positive effects on gut health by modulating the gut microbiota composition, improving nutrient absorption and reducing digestive disorders. …”
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992
Butyrate attenuates sympathetic activation in rats with chronic heart failure by inhibiting microglial inflammation in the paraventricular n...
Published 2024-06-01“…Butyrate is generated by gut microbiota and influences numerous physiological and pathological processes in the host. …”
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993
Protection of Fecal Microbiota Transplantation in a Mouse Model of Multiple Sclerosis
Published 2020-01-01“…Given the growing evidence of a link between gut microbiota (GM) dysbiosis and multiple sclerosis (MS), fecal microbiota transplantation (FMT), aimed at rebuilding GM, has been proposed as a new therapeutic approach to MS treatment. …”
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994
From chaos to order: optimizing fecal microbiota transplantation for enhanced immune checkpoint inhibitors efficacy
Published 2025-12-01“…We investigate how FMT modulates gut microbiota composition, microbial metabolite profiles, and the tumor microenvironment, thereby influencing ICIs effectiveness. …”
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995
Reshaping lipid metabolism with long-term alternate day feeding in type 2 diabetes mice
Published 2025-02-01“…Microbiome studies and predicted functional analysis of gut microbiota showed that IF increased beneficial bacteria involved in sphingolipid (SL) metabolism. …”
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996
Effects of cassava pellets and enzymes addition on growth performance, meat quality, serum biochemical indices and cecum microbiota of broilers
Published 2025-01-01“…The composition of feed significantly influences the growth performance and gut microbiota of broiler chicks, impacting their overall health and productivity. …”
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997
The prebiotic potential of dietary onion extracts: shaping gut microbial structures and promoting beneficial metabolites
Published 2025-01-01“…The findings underscore the potential of onion extracts to improve gut health by enriching specific beneficial bacteria and metabolic pathways, thereby supporting the development of functional foods aimed at improving gut microbiota composition and metabolic health.…”
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998
FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression
Published 2025-01-01“…Abstract Introduction Colorectal cancer (CRC) is the second most common cause of cancer-related deaths globally. The gut microbiota, along with adenomatous polyps (AP), has emerged as a plausible contributor to CRC progression. …”
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999
Diet-microbiome covariation across three giraffe species in a close-contact zone
Published 2025-04-01“…The biodiverse group of ruminant mammals are entirely dependent on their gut microbiota to extract energy and nutrients from their foods, making these symbionts vital to survival. …”
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1000
The gut–kidney axis is regulated by astragaloside IV to inhibit cyclosporine A-induced nephrotoxicity
Published 2025-01-01“…This study aimed to verify the ameliorative effects of AS-IV on CICN and further explore the mechanisms underlying the modulation of the “gut–transcriptome–metabolome coexpression network” by AS-IV within the context of the “gut–kidney axis” to improve CICN.MethodsFive groups of 40 mice were studied: a normal group (N, olive oil), a model group (M, CsA, 30 mg kg-−1 d−1), a low-dose AS-IV group (CsA + AS-IV, 30 mg kg−1 d−1 + 10 mg kg−1 d−1), a high-dose AS-IV group (CsA + AS-IV, 30 mg kg−1 d−1 + 20 mg kg−1 d−1), and a valsartan group (CsA + Val, 30 mg kg−1 d−1 + 10 mg kg−1 d−1). The gut microbiota, renal transcriptome, and urine metabolome were separately detected to construct a gut–transcriptome–metabolome coexpression network. …”
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