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961
Microencapsulation of Probiotic Strains by Lyophilization Is Efficient in Maintaining the Viability of Microorganisms and Modulation of Fecal Microbiota in Cats
Published 2020-01-01“…In conclusion, the supplementation of cat diets with probiotics positively affected the gut microbiota. However, the results reinforce that probiotic microorganisms must be incorporated into the animal feed via effective mechanisms to withstand harsh processing conditions and storage.…”
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962
Classification of Nanomaterial Drug Delivery Systems for Inflammatory Bowel Disease
Published 2025-02-01“…Haichen Wang,1,* Feifei Zhou,2,* Mengdan Shen,1 Ronglin Ma,1 Qiang Yu1 1Department of Gastroenterology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu, 215002, People’s Republic of China; 2Department of Gastroenterology, Suzhou City Wuzhong District Chengnan Street Community Health Service Center, Suzhou, Jiangsu, 215002, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qiang Yu; Ronglin Ma, Email yuqiang0102sz@163.com; maronglin573@163.comAbstract: Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, primarily arises from defects in the colonic barrier, imbalances of the gut microbiota, and immune response issues. These complex causes make it difficult to achieve a complete cure. …”
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963
Combined analysis of 16S rRNA sequencing and metabolomics reveals the growth-promoting mechanism of compound probiotics in zig-zag eel (Mastacembelus armatus)
Published 2025-03-01“…The intestinal physiology was reflected by intestinal histology, intestinal digestive enzyme, and antioxidant enzyme activity (P < 0.05). 16S rRNA sequencing was used to analyze the gut microbiota of different groups. The MIX probiotics can promote the activities of intestinal digestive enzymes and antioxidant enzymes by promoting the bacteria Brevundimonas, Bacillus, and Rhodococcus in the intestine. …”
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964
Characterization of squash polysaccharide and the anti-diabetic effect on type 2 diabetic rat revealed by urine metabolomics analysis
Published 2024-09-01“…The regulation of nicotinamide N-oxide, histamine, cis-aconitate, citrate, L-malic acid, 3-(3-hydroxyphenyl) propanoic acid and N-acetyl-L-aspartic acid were mainly associated with energy metabolism, gut microbiota and inflammation. Study of surface plasmon resonance revealed the binding kinetics with galectin-3 (Gal-3) and fibroblast growth factor 2 (FGF2). …”
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965
Food-derived bio-functional peptides for the management of hyperuricemia and associated mechanism
Published 2024-07-01“…In addition, novel action mechanism mediated by gut microbiota was discussed, providing different insights from classical mechanism. …”
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966
Evolution of Alzheimer’s Disease Therapeutics: From Conventional Drugs to Medicinal Plants, Immunotherapy, Microbiotherapy and Nanotherapy
Published 2025-01-01“…The modulation of the gut microbiota is also addressed as a peripheral strategy that could influence neuroinflammatory and degenerative processes in the brain. …”
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967
Potential common targets of music therapy intervention in neuropsychiatric disorders: the prefrontal cortex-hippocampus -amygdala circuit (a review)
Published 2025-02-01“…This may be closely related to the release of signaling molecules such as monoamine neurotransmitters, the glutamatergic system, the gut-microbiota-brain axis, pro-inflammatory cytokines and the endogenous opioid peptide system. …”
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968
Diverse Profiles of Toll-Like Receptors 2, 4, 7, and 9 mRNA in Peripheral Blood and Biopsy Specimens of Patients with Celiac Disease
Published 2018-01-01“…Upregulation of TLR4 and TLR9 suggests the contribution of gut microbiota or dysregulation of the immune response to commensal flora in small bowel mucosa in celiac patients.…”
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969
Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites
Published 2024-12-01“…These findings provide new insights into probiotics as a potential treatment for sarcopenia by modulating gut microbiota metabolism.…”
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970
Bibliometric insights into astrocytic roles in depression and treatment
Published 2025-01-01“…Keywords such as “synaptic plasticity,” “astrocytes,” and “neuroinflammation” revealed research trends focusing on molecular mechanisms, gut microbiota, and inflammation.ConclusionThis is the first bibliometric study to comprehensively summarize the research trends and advancements regarding astrocytes in depression and its treatment. …”
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971
Intestinal microbiota as biomarkers for different colorectal lesions based on colorectal cancer screening participants in community
Published 2025-02-01“…However, the utilization of intestinal microbiota for identify the lesions in different procedures in CRC screening populations remains limited.MethodsA total of 529 high-risk individuals who underwent CRC screening were included, comprising 13 advanced adenomas (Aade), 5 CRC, 59 non-advanced adenomas (Nade), 129 colon polyps (Pol), 99 cases of colorectal inflammatory disease (Inf), and 224 normal controls (Nor). 16S rRNA gene sequencing was used to profile the intestinal microbiota communities. The Gut Microbiota Health Index (GMHI) and average variation degree (AVD) were employed to assess the health status of the different groups.ResultsOur findings revealed that the Nor group exhibited significantly higher GMHIs and the lowest AVD compared to the four Lesion groups. …”
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972
Structure characterization of Grifola frondosa polysaccharide and its effect on insulin resistance in HFD-fed mice
Published 2025-01-01“…GFP significantly alleviated gut microbiota disturbance caused by HFD and increased the production of short-chain fatty acids, and further reduced the expression of LPS/TLR4 inflammatory pathway. …”
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973
Prominence of Microbiota to Predict Fibrous Stenosis in Crohn’s Disease
Published 2025-02-01“…Additionally, we explored functional differences in intestinal microbiota between the two groups.Results: : Our investigation of fecal samples revealed no significant differences in the gut microbiota structure between patients with fibrous stenosis and those without stenosis in CD. …”
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974
Multi-biofluid metabolomics analysis of allergic respiratory rhinitis and asthma in early childhood
Published 2025-01-01“…Their short-chain fatty acid metabolites related to IgE levels emphasize the significant role of the gut microbiota in childhood rhinitis and asthma.…”
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975
Metabolomics Biomarkers in Prediction of Sudden Infant Death Syndrome: The Role of Short Chain Fatty Acids
Published 2025-01-01“…In this context, SCFA are essential products of the fermentation process by gut microbiota, hold particular interest. SCFA are integral to energy regulation and metabolism, influencing overall well-being. …”
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976
Maternal milk fat globule membrane enriched gut L. murinus and circulating SCFAs to improve placental efficiency and fetal development in intrauterine growth restricted mice model
Published 2025-12-01“…Milk fat globule membrane (MFGM) is known for its diverse bioactive functions, while the effects of gestational MFGM supplementation on the maternal gut microbiota, placental efficiency, and fetal development remained unclear. …”
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977
Could Infectious Agents Play a Role in the Onset of Age-related Macular Degeneration? A Scoping Review
Published 2025-03-01“…Articles dealing with the oral and gut microbiota were not included but we provide a brief summary of high-quality literature reviews recently published on the subject. …”
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978
Comparison of In Vitro Biotransformation of Olive Polyphenols Between Healthy Young and Elderly
Published 2025-01-01“…Upon ingestion, a substantial fraction of these polyphenols reaches the colon where they undergo extensive metabolism by the gut microbiota. Host characteristics, like age, can influence the composition of the gut microbiome, potentially affecting the biotransformation of these compounds. …”
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979
Fecal Microbiota Transplantation as Therapy for Treatment of Active Ulcerative Colitis: A Systematic Review and Meta-Analysis
Published 2021-01-01“…Increasing evidence supports the role of the gut microbiota in the etiology of ulcerative colitis (UC). …”
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980
Lactiplantibacillus plantarum AR113 alleviates microbiota dysbiosis of tongue coating and cerebral ischemia/reperfusion injury in rat
Published 2024-07-01“…AR113 partly restored I/R induced change of TCM and gut microbiota with significantly improved neurological deficit, relieved histopathologic change, increased activities of antioxidant enzymes, and decreased contents of oxidative stress biomarkers. …”
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