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801
Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway
Published 2025-02-01“…The disturbance of gut microbiota aggravates pathogenic bacteria invasion and gut barrier injury. …”
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802
Rat models of postintracerebral hemorrhage pneumonia induced by nasal inoculation with Klebsiella pneumoniae or intratracheal inoculation with LPS
Published 2025-01-01“…Kp challenge exacerbated the gut microbiota dysbiosis and fecal metabolic profile disorders, which were characterized by abnormal sphingolipid metabolism especially elevated ceramide levels; increased levels of neurotoxic quinolinic acid and an upregulation of tryptophan (Trp)–serotonin–melatonin pathway. …”
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803
Lachnospiraceae-bacterium alleviates ischemia-reperfusion injury in steatotic donor liver by inhibiting ferroptosis via the Foxo3-Alox15 signaling pathway
Published 2025-12-01“…Dysbiosis of the gut microbiota has been implicated in modulating IRI, and Lachnospiraceae plays a pivotal role in regulating host inflammatory and immune responses, but its specific role in liver transplantation IRI remains unclear. …”
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804
New horizons in the treatment of psoriasis: Modulation of gut microbiome
Published 2025-01-01“…First, we outline the current knowledge on the unique gut microbiota patterns implicated in the pathogenesis of psoriasis. …”
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805
Application of Metabolomics to Study Effects of Bariatric Surgery
Published 2018-01-01“…Detected changes pertain to amino acid, lipids, carbohydrates, or gut microbiota alterations. It proves that including bariatric surgery to metabolic surgery is warranted. …”
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806
Dietary content and eating behavior in ulcerative colitis: a narrative review and future perspective
Published 2025-01-01“…This review provides insights into the impact of dietary content and eating behaviors on UC, focusing on specific food, food groups, nutrients, and intermittent fasting, while providing a detailed explanation of why the gut microbiota may mediate the sustained effects of diet across all stages of UC. …”
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807
The Potential of Food Protein-Derived Bioactive Peptides against Chronic Intestinal Inflammation
Published 2020-01-01“…The mechanism, pathways, and future perspectives of BAPs as the potential sources of therapeutic treatments to alleviate intestinal inflammation are provided, including nuclear factor-κB, mitogen-activated protein kinase, Janus kinase-signal transducer and activator of transcription, and peptide transporter 1 (PepT1), finding that PepT1 and gut microbiota are the promising targets for BAPs to alleviate the intestinal inflammation. …”
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808
The Impact of Antidepressants on Gut Microbiome and Depression Management
Published 2024-07-01“…Restoring healthy gut microbiota can improve gastrointestinal and mental health outcomes, suggesting a promising avenue for integrated therapeutic approaches. …”
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809
Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases
Published 2023-01-01“…They can also increase or reduce neuronal damage by regulating the body’s signaling pathways, immune system, stem cells, gut microbiota, etc. They can not only affect the occurrence of diseases and exacerbate disease progression but also promote neuronal repair and reduce apoptosis, to prevent and slow down the development of diseases. …”
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810
Probiotics for Alleviating Alcoholic Liver Injury
Published 2019-01-01“…Alcohol disrupts the composition of intestinal flora; probiotics modulate the gut microbiota and reverse alcohol-associated intestinal barrier dysfunction by decreasing intestinal mucosal permeability and preventing intestinal bacteria from translocating. …”
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811
A molecular toolkit for heterologous protein secretion across Bacteroides species
Published 2024-11-01“…Abstract Bacteroides species are abundant, prevalent, and stable members of the human gut microbiota, making them a promising chassis for developing long-term interventions for chronic diseases. …”
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812
Gut microbial profiles of patients with optic neuritis or myasthenia gravis
Published 2025-02-01“…Conclusion We have identified significant alterations in the gut microbiota of patients with ON or MG, and importantly, a notable reduction in intestinal probiotics.…”
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813
Intestinal Barrier, Permeability and Nonspecific Inflammation in Functional Gastrointestinal Disorders
Published 2020-09-01“…Intestinal mucosal barrier is composed of several elements: pre-epithelial barrier, a mucosal lining of epithelium; epithelial barrier that leverages tight junctional structures and high regenerative capacity of epithelium; post-epithelial barrier established by immune cells and blood vessels. Gut microbiota profile may also be constituent of the intestinal mucosal barrier. …”
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814
Association between Probiotics and Modulation of Gut Microbial Community Composition in Colorectal Cancer Animal Models: A Systematic Review (2010–2021)
Published 2023-01-01“…The goal of this systematic review was to gather the preclinical studies that examined the impact of probiotics on the alteration of gut microbiota profiles (bacterial communities) and their link to colorectal carcinogenesis as well as the potential processes involved. …”
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815
Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer’s Disease
Published 2022-01-01“…Moreover, TLR4 regulates apoptosis, autophagy, and gut microbiota and is closely related to AD. This article reviews the role of TLR4 in the pathogenesis of AD and a range of potential therapies targeting TLR4 for AD. …”
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816
Microbiota, parasitic infections and their relationship with nutritional status and neurocognitive functioning in children from Ecuador—Proyecto Guagua: research protocol for a cro...
Published 2025-01-01“…Stool samples are collected to analyze the gut microbiota and determine the presence of parasites. …”
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817
Discovery of the microbiota-gut-brain axis mechanisms of acupuncture for amnestic mild cognitive impairment based on multi-omics analyses: A pilot study
Published 2025-03-01“…In addition, multi-omics was performed to detect changes in brain function, gut microbiota, and serum metabolites. Generalized estimating equations were used to estimate the outcomes, and correlational analyses were performed to explore the relationships between the clinical and multi-omics data. …”
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818
Modified neuroimmune processes and emotional behaviour in weaned and late adolescent male and female mice born via caesarean section
Published 2024-11-01“…During C-section delivery, newborns are not exposed to the vaginal commensal flora, which impedes the early establishment of the gut microbiota. The latter is essential for adequate neuro-immune processes to take place during infancy. …”
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819
Evaluating the effects of dietary glutamine on performance, carcass traits, blood biochemistry, and intestine morphology in laying quail
Published 2025-03-01“…This study investigated the effects of dietary glutamine (Gln) supplementation on the performance, carcass characteristics, blood biochemistry, intestinal morphology, and gut microbiota of laying quail over a 12-week period, with analyses conducted after 6 and 12 weeks of supplementation. …”
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820
Fecal microbiota is more stable during degradation and more diverse for ex situ cheetahs in Namibia compared to the USA
Published 2025-01-01“…The relationships between gut microbiota and animal health are an important consideration increasingly influential in the management of wild and ex situ endangered species, such as the cheetah (Acinonyx jubatus). …”
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