Brain-Derived Neurotrophic Factor and Nerve Growth Factor Therapeutics for Brain Injury: The Current Translational Challenges in Preclinical and Clinical Research by Serena-Kaye Sims, Brynna Wilken-Resman, Crystal J. Smith, Ashley Mitchell, Lilly McGonegal, Catrina Sims-Robinson

“…Neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) serve as potential therapeutic options to increase neural repair and recovery as they promote neuroprotection and regeneration. …”
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Relationship between serum insulin-like growth factor 1 levels and ischaemic stroke: a systematic review and meta-analysis by Jinhui Li, Simiao Chen, Lan He, Yangni Li, Weinan Yang, Yishu Zhang, Lincheng Zhang, Yuyan Zhang

“…Objective To assess the association of insulin-like growth factor 1 (IGF-1) with the risk of incident ischaemic stroke and outcome after ischaemic stroke.Design A systematic review of primary studies.Setting Hospitals in Western Sweden, Italy, China and Denmark.Methods A search was carried out in eligible studies in electronic databases (PubMed, Scopus, Embase, China National Knowledge Infrastructure and Web of Science) updated to 29 December 2020. …”
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An immunoregulation PLGA/Chitosan aligned nanofibers with polydopamine coupling basic fibroblast growth factor and ROS scavenging for peripheral nerve regeneration by Xiaokun Chen, Jihai Xu, Feng Qin, Ziyuan Yang, Xueyuan Li, Miao Yu, Ming Li, Yanhua Wang, Wang Xin

“…The PDA coating provided ROS scavenging and immune modulation functions. The bFGF growth factor attached to the PDA coating facilitated sustained release, enhancing Schwann cell functionality and stimulating neurite outgrowth. …”
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Effects of Bariatric Surgeries on Fetuin-A, Selenoprotein P, Angiopoietin-Like Protein 6, and Fibroblast Growth Factor 21 Concentration by Jakub Poloczek, Wojciech Kazura, Ewa Kwaśnicka, Janusz Gumprecht, Jerzy Jochem, Dominika Stygar

“…Many of them, including fetuin-A, selenoprotein P, angiopoietin-like protein 6, and fibroblast growth factor 21, have been linked to metabolic dysfunctions. …”
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Comparison of Two Preparation Methods for Platelet-Rich Plasma Eye Drops for Release of Growth Factors and De-Epithelization Rabbit Model by Tatsuhiko Kobayashi, Takashi Suzuki, Tomohiko Saito, Takashi Itokawa, Yuichi Hori

“…To compare two platelet-rich plasma (PRP) preparation methods (double spin (D-PRP) and TriCell PRP (T-PRP)) for eye drops, concentration yields of platelets and other cells, release of growth factors, and efficacy of the de-epithelization rabbit model. …”
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Fibroblast Growth Factor Receptor 3 (FGFR3)–Analyses of the S249C Mutation and Protein Expression in Primary Cervical Carcinomas by Haiyan Dai, Ruth Holm, Gunnar B. Kristensen, Vera M. Abeler, Anne‐Lise Børresen‐Dale, Åslaug Helland

“…Fibroblast growth factor receptor 3 (FGFR3) seems to play an inhibitory role in bone development, as activating mutations in the gene underlie disorders such as achondroplasia and thanatophoric dysplasia. …”
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Polymorphisms of Tumor Necrosis Factor-α, Transforming Growth Factor-β, and Interleukin-10 in Asthma Associated with Olive Pollen Sensitization by Blanca Cárdaba, David Calzada, Selene Baos, Miriam Aguerri, Joaquín Quiralte, Carlos Lahoz

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Cyclic AMP stimulates platelet-derived growth factor B chain mRNA expression in murine macrophage cell lines by Elizabeth J. Kovacs, Susan VanStedum

“…Prior to treatment, macrophages do not express interleukin-1β, but do express low levels of tumour necrosis factor α and platelet-derived growth factor B chain mRNAs. After culture with cAMP-inducers, including PGE2, dibutyryl cAMP and forskolin, PDGF B chain mRNA is induced. …”
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Serum levels of tumor necrosis factor-alpha and vascular endothelial growth factor as markers of disease activity in patients with axial spondyloarthritis by Mahendran Bhuvanesh, Chilkuri Balaji, Chinnadurai Saranya, Ramamoorthy Ramesh, Trichangode Natesan Tamilselvam, Sankaralingam Rajeswari

“…This study aims to investigate the role of vascular endothelial growth factor (VEGF) and tumor necrosis factor-alpha (TNF-α) as markers of disease activity in patients with axSpA. …”
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Gene Profiles in the Early Stage of Neuronal Differentiation of Mouse Bone Marrow Stromal Cells Induced by Basic Fibroblast Growth Factor by Lili Yu, Wei Hong, Haijie Yang, Yin Yan Xia, Zhiwei Feng

“…Subjected to basic fibroblast growth factor (bFGF) treatment, a typical neuronal phenotype was induced in these cells, as supported by neuronal morphology, induction of neuronal markers, and relevant electrophysiological excitability. …”
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Injectable Hierarchical Bioactive Hydrogels with Fibroblast Growth Factor 21/Edaravone/Caffeic Acid Asynchronous Delivery for Treating Parkinson's Disease by Junpeng Xu, Peng Dai, Chen Zhang, Na Dong, Caiyan Li, Chonghui Tang, Zhihao Jin, Shih‐Ho Lin, Luyang Ye, Tianmiao Sun, Yukai Jin, Fenzan Wu, Lihua Luo, Ping Wu, Shengcun Li, Xiaokun Li, Shan‐hui Hsu, Dawei Jiang, Zhouguang Wang

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Unlocking the full potential of resistance training: a comparative analysis of low- and high-intensity effects on neurotrophic growth factors and homocysteine by Chongwen Zuo, Yi Yin, Zhiyang Zheng, Ren Mu, Yuxin Liang, Shan Wang, Chaoqun Ye

“…Blood samples were collected at three time points: pre-training, post training, and after 30 min of rest to measure changes in serum lactate, serum brain-derived neurotrophic factor (BDNF), insulin-like growth factor 1 (IGF-1), vascular endothelial growth factor (VEGF), irisin, and plasma homocysteine (Hcy) levels. …”
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(-)-Epigallocatechin Gallate Reduces Platelet-Derived Growth Factor-BB-Stimulated Interleukin-6 Synthesis in Osteoblasts: Suppression of SAPK/JNK by Shinji Takai, Rie Matsushima-Nishiwaki, Seiji Adachi, Hideo Natsume, Chiho Minamitani, Jun Mizutani, Takanobu Otsuka, Haruhiko Tokuda, Osamu Kozawa

“…We previously showed that the mitogen-activated protein (MAP) kinase superfamily, p44/p42 MAP kinase, p38 MAP kinase, and stress-activated protein kinase (SAPK)/c-Jun N-terminal (JNK), positively plays a part in the platelet-derived growth factor-BB- (PDGF-BB-) stimulated synthesis of interleukin-6 (IL-6), a potent bone resorptive agent, in osteoblast-like MC3T3-E1 cells while Akt and p70 S6 kinase negatively regulates the synthesis. …”
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The Increased Circulating Plasma Levels of Vascular Endothelial Growth Factor in Patients with Type 1 Diabetes Do Not Correlate to Metabolic Control by Kailash Singh, Stellan Sandler, Daniel Espes

“…To characterize the plasma levels of vascular endothelial growth factor (VEGF) in type 1 diabetes mellitus (T1D) and its relation to both present and historical metabolic control and microvascular complications. …”
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Vascular Endhothelial Growth Factor levels in medium-intensity versus low-intensity exercise with blood flow restriction in elderly women by Nanda Aulya Ramadhan, Damayanti Tinduh, Nuniek Nugraheni, Imam Subadi, Inggar Narasinta, Soenarnatalina Melaniani

“…Vascular Endothelial Growth Factor has a role in angiogenesis and increasing muscle mass through increasing the number and function of satellite cells. …”
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Colonic growth factors (G-CSF, GM-CSF) and chemokines (MCP-1, MIP-1β) in severe ulcerative colitis by Yevgeny A. Konovich, K. Ye. Shirokikh, M. V. Shapina, Igor L. Khalif

“…To determine the content of growth factors (G-CSF, GM-CSF) and chemokines (MCP-1, MIP-1β) in resected colon specimens of patients with severe ulcerative colitis (UC). …”
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Long-Term Effect of Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Injections in Choroidal Neovascularization Secondary to Angioid Streaks by Sónia Torres-Costa, João Bernardes, Sofia Sousa Mano, Joana Medeiros-Pinto, Ana Carolina Abreu, Maria João Furtado, Rufino Silva, Carlos Marques-Neves, Fernando Falcão-Reis, Ângela Carneiro, Luísa Colaço, Manuel Falcão

“…This study aimed to evaluate the long-term effectiveness of intravitreal anti-vascular endothelial growth factor (VEGF) injections in the treatment of choroidal neovascularization (CNV) associated with angioid streaks. …”
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Management of Post-implant Inferior Alveolar Neuropathy, Utilizing Autologous Fibrin Glue, Concentrated Growth Factors and Enriched Bone Graft Matrix—A Case Report with 5 Years Follow-Up by Siva Prakash Dhanaraj, Sriganesh Anguswamy, Narmadha Dominic, Arun Sarfoji, Kayathri, Ashwini Sukanya

Subjects: “…concentrated growth factors…”
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Regenerative potential of concentrated growth factor compared to platelet-rich fibrin in treatment of necrotic mature teeth: a randomized clinical trial by Taghreed Salah, Wael Hussein, Heba Abdelkafy

“…Abstract Aim This study aimed to compare the potential of two regenerative endodontic procedures, platelet-rich fibrin (PRF) and concentrated growth factor (CGF), in the treatment of mature permanent teeth with necrotic pulps and periapical radiolucency. …”
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Sustained and Efficient Delivery of Antivascular Endothelial Growth Factor by the Adeno-associated Virus for the Treatment of Corneal Neovascularization: An Outlook for Its Clinical Translation by Mengzhen Xie, Lixiang Wang, Yingping Deng, Ke Ma, Hongbo Yin, Xiaolan Zhang, Xingye Xiang, Jing Tang

“…In addition, to overcome the barriers of the short duration and inadequate penetration of conventional formulations of antivascular endothelial growth factor (VEGF), multiple novel drug delivery systems, including adeno-associated virus (AAV)-mediated transfer have gone through the full process of bench-to-bedside translation. …”
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