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Formulation and evaluation of hyaluronic acid and adipic acid dihydrazide modified graphene quantum dot-based nanotherapeutics for paclitaxel-targeted delivery in breast cancer
Published 2025-01-01“…The suggested study is innovative since anticancer drug delivery using HA-GQDs NTCs with adhesive capabilities of ADH has not been previously described. Graphical Abstract Diagrammatic representation of the preparation of PAC@HA-ADH-GQDs NTCs for breast cancer targeting…”
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2163
Design of a new class of broad-spectrum therapeutics targeted to drug-resistant bacteria
Published 2024-12-01“…The anthraquinone-TPP conjugates (4) and (5) were active in vitro against Mycobacterium smegmatis (graphical abstract) and were equipotent as determined by their MIC values; in contrast to MRSA, the less hydrophobic (4) had 2-fold greater bactericidal potency than (5) as measured by their MBC values. …”
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2164
NAT10 promotes ovarian cancer cell migration, invasion, and stemness via N4-acetylcytidine modification of CAPRIN1
Published 2025-02-01“…These findings suggest that NAT10 may be a promising therapy target for OC. Graphical abstract…”
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2165
Hydrogeochemical Characteristics and Formation of Low-Temperature Geothermal Waters in Mangbang-Longling Area of Western Yunnan, China
Published 2021-01-01“…The reservoir temperatures of low-temperature geothermal waters ranged from 111°C to 126°C estimated by silica geothermometry and the silicon-enthalpy graphic method. Low-temperature geothermal waters circulated at the largest depth of 1794–2077 m where deep high-temperature geothermal waters were involved. …”
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2166
Activation of implementation of information modelling technologies in the Russian construction industry
Published 2023-12-01“…The research is based on system, process and situational approaches, methods of comparative and factor analysis of the results of foreign and domestic experience, as well as methods of economic-mathematical and graphic modelling. This methodological set allowed assessing the influence of factor space on the processes of applying BIM at the stages of the life cycle of ICP and to propose an algorithm of actions to intensify the implementation of BIM in the domestic construction industry.Results. …”
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2167
Linearity of natural versus laboratory-imparted remanence demagnetization diagram and reliability of relative paleointensity estimation
Published 2025-02-01“…In sediments with changing proportion of magnetofossils, normalization with IRM may work better than ARM. Graphical Abstract…”
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2168
Minimal sourced and lightweight federated transfer learning models for skin cancer detection
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2169
Unique Design of Learning Studio Spaces: A Case Study of The Department of Applied Design and Fine Art Kabale University.
Published 2023“…It can be for the purpose of acting, architecture, painting, pottery (ceramics), sculpture, origami, woodworking, scrapbooking, photography, graphic design, filmmaking, animation, industrial design, radio or television production broadcasting or the making of music. …”
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Thesis -
2170
Unique Design of Learning Studio Spaces: A Case Study of the Department of Applied Design and Fine Art Kabale University.
Published 2023“…It can be for the purpose of acting, architecture, painting, pottery (ceramics), sculpture, origami, woodworking, scrapbooking, photography, graphic design, filmmaking, animation, industrial design, radio or television production broadcasting or the making of music. …”
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Thesis -
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Dysregulation of transposable elements and PIWI-interacting RNAs in myelodysplastic neoplasms
Published 2025-01-01“…Conclusions Our findings demonstrate the parallel dysregulation of TEs and piRNAs in HR-MDS patients, highlighting their potential role in MDS progression and indicating that the PIWIL2 level is a promising molecular marker for prognosis. Graphical Abstract…”
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2173
Improving 10-year cardiovascular risk prediction in patients with type 2 diabetes with metabolomics
Published 2025-01-01“…Given the latest cost reduction and standardization efforts, NMR metabolomics has the potential for translation into the clinical routine. Graphical abstract…”
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2174
Inhibition of METTL14 overcomes CDK4/6 inhibitor resistance driven by METTL14-m6A-E2F1-axis in ERα-positive breast cancer
Published 2025-01-01“…Together, our findings reveal the mechanism of CDK4/6i resistance and provide a strategy for overcoming CDK4/6i resistance via METTL14 inhibition. Graphical Abstract…”
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2175
Salvage transoral laser microsurgery for early local recurrence of glottic squamous cell cancer
Published 2023-05-01“…Conclusion Salvage TLM can be used as an effective treatment option for suitable patients after a full, comprehensive, and careful assessment of the characteristics of early locally recurrent glottic carcinoma. Graphical Abstract…”
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Development of a patient reported outcome instrument for chronic sialadenitis
Published 2022-02-01“…Level of evidence Level V. Graphical Abstract…”
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2177
Feedback loop centered on MAF1 reduces blood–brain barrier damage in sepsis-associated encephalopathy
Published 2025-01-01“…Clinical trial number: not applicable. Graphical Abstract…”
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2178
The burden of irritable bowel syndrome and functional dyspepsia in Poland: a cross-sectional study from West Pomeranian Voivodship
Published 2025-01-01“…Our findings highlight the need for regional studies to understand local DGBI prevalence, aiding targeted healthcare strategies. Graphical Abstract…”
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aPD-L1-facilitated theranostic and tumor microenvironment remodeling of pancreatic cancer via docetaxel-loaded phase-transformation nanoparticles triggered by low-intensity pulsed...
Published 2025-01-01“…In conclusion, aPD-L1-modified liquid‒vapor phase-transformation nanoparticles loaded with docetaxel (DTX) and PFP were successfully combined with ultrasound for the molecular diagnosis and targeted treatment of PDAC. aPDL1-DTX/PFP@Lipid could reshape the PDAC TME, offering a new approach for ultrasound-mediated diagnosis and treatment with promising clinical applications. Graphical Abstract…”
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2180
Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma
Published 2023-05-01“…Future studies will address the underlying molecular mechanisms by which ZNF154 expression in HNSCC contributes to the control of cell growth and migration. Graphical abstract…”
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