Pan-cancer analysis shows that TNFSF4 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including liver cancer by Zhaoda Deng, Lincheng Li, Zihe Meng, Guineng Zeng, Rui Cao, Rong Liu

“…Our study shows that TNFSF4 is a promising prognostic and immunotherapeutic biomarker in some malignant tumors. Graphical Abstract…”
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PLGA confers upon conventional nonfluorescent molecules luminescent properties to trigger 1O2-induced pyroptosis and immune response in tumors by Lan Zou, Rujing Wang, Mengnan Zhao, Yuke Li, Chen Sun, Jinjin Xie, Yan Chen, Qian Jing, Dandan Mi, Sanjun Shi

“…This discovery holds the potential to facilitate the application of light-controlled pyroptosis in antitumor therapy, marking a promising stride toward innovative approaches in cancer treatment. Graphical abstract…”
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An Architecture-Tracking Approach to Evaluate a Modular and Extensible Flight Software for CubeSat Nanosatellites by Carlos E. Gonzalez, Camilo J. Rojas, Alexandre Bergel, Marcos A. Diaz

“…We also present an <italic>architecture tracking methodology</italic> to verify and control the flight software quality criteria during the development process through the use of <italic>graphical software analysis tools</italic> and agile programming techniques. …”
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Predictive value of preoperative pan-immune-inflammation value index in the prognosis of oral cancer patients undergoing radical resection by Weihai Huang, Yulan Lin, Enling Xu, Yanmei Ji, Jing Wang, Fengqiong Liu, Fa Chen, Yu Qiu, Bin Shi, Lisong Lin, Baochang He

“…Conclusions PIV is an independent predictor of prognosis in patients with oral squamous cell carcinoma, and a column-line graphical model based on PIV can effectively predict prognosis.…”
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First evidence of the effectiveness of a field application of RNAi technology in reducing infestation of the mite Varroa destructor in the western honey bee (Apis mellifera) by Francesca Bortolin, Emanuele Rigato, Sergio Perandin, Anna Granato, Laura Zulian, Caterina Millino, Beniamina Pacchioni, Franco Mutinelli, Giuseppe Fusco

“…This study supports the potential of RNAi as a promising alternative to chemical pesticides, offering a targeted, efficient and sustainable solution for managing V. destructor in honey bee populations. Graphical Abstract…”
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Extracellular vesicle surface engineering with integrins (ITGAL & ITGB2) to specifically target ICAM-1-expressing endothelial cells by Markus Bergqvist, Kyong-Su Park, Nasibeh Karimi, Lijuan Yu, Cecilia Lässer, Jan Lötvall

“…We conclude that LFA-1-expressing EVMyd88 may be a candidate suitable for delivering therapeutic peptides in inflammatory diseases associated with TLR-activation. Graphical Abstract…”
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Simultaneously delivery of functional gallium ions and hydrogen sulfide to endow potentiated treatment efficacy in chemo- and PARPi-resistant ovarian cancer by Sangsang Tang, Yangyang Li, Yifeng Fang, Mengyan Tu, Shenglong Wu, Yixuan Cen, Junfen Xu

“…Altogether, our results demonstrated a potentially safe and practical strategy by using Ga2S3-BSA NMs to combat drug resistance in platinum-resistant OC. Graphical Abstract…”
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Exploiting venom toxins in paratransgenesis to prevent mosquito-borne disease by Stephanie French, Rachael Da Silva, Janet Storm, Christida E. Wastika, India Cullen, Martijn ten Have, Grant L. Hughes, Cassandra M. Modahl

“…We postulate the potential to apply this principle to target arboviruses using antiviral toxin effectors. Graphical Abstract…”
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Entropy analysis of Darcy–Forchheimer flow of couple-stress TiO2-CoFe2O4/engine oil based hybrid nanofluid between two rotating disks considering hall effect by Sk Enamul, Seetalsmita Samal, Surender Ontela

“…Critical parameters such as the inertial coefficient, heat source parameter, nanoparticle concentration, and magnetic field parameter are analyzed graphically. These analyses explore their effects on velocity profiles, temperature distribution, and entropy generation. …”
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Interdependence Between River Aquifer Groundwater Flow and Temperature–Depth Profiles: Type Curves Based on Pi Theorem and Numerical Simulations by José Antonio Jiménez-Valera, Iván Alhama, Carlos Duque, David Labat

“…Experimental studies and numerical modeling have supported analytical solutions; these solutions have been proposed for specific cases in which the aim has been to understand discharge/recharge and aquifer characterization. In this study, new graphical solutions or type curves are provided to estimate the subsurface flow and thermal–mechanical parameters in anisotropic porous media. …”
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Targeting OAS3 for reversing M2d infiltration and restoring anti-tumor immunity in pancreatic cancer by Shaopeng Zhang, Ximo Xu, Kundong Zhang, Changzheng Lei, Yitian Xu, Pengshan Zhang, Yuan Zhang, Haitao Gu, Chen Huang, Zhengjun Qiu

“…In conclusion, OAS3 presents as a promising immune therapeutic target for reversing IL-10highVEGF-AhighM2d infiltration and restoring CD8+T cell-mediated anti-tumor immunity in pancreatic cancer. Graphical abstract…”
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Novel numerical and artificial neural computing with experimental validation towards unsteady micropolar nanofluid flow across a Riga plate by Muhammad Bilal, F. Maiz, Muhammad Farooq, Hijaz Ahmad, Mohammad Khalid Nasrat, Hassan Ali Ghazwani

“…The influence of physical constraints on the dimensionless temperature, concentration, microrotation, and velocity distributions are graphically displayed and discussed. Numerical results for skin friction, Sherwood, and Nusselt numbers are presented in tabular form. …”
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Modeling saturation exponent of underground hydrocarbon reservoirs using robust machine learning methods by Abhinav Kumar, Paul Rodrigues, A. K. Kareem, Tingneyuc Sekac, Sherzod Abdullaev, Jasgurpreet Singh Chohan, R. Manjunatha, Kumar Rethik, Shivakrishna Dasi, Mahmood Kiani

“…The sensitivity analysis indicates that resistivity index and true resistivity have direct correlation with the saturation exponent while porosity, absolute permeability and water saturation is inversely related with saturation exponent. In addition, the graphical-based and statistical-based evaluations illustrate that AdaBoost and ensemble learning models outperforms all other developed data-driven intelligent models as these two models are associated with lowest values of mean square error (adaptive boosting: 0.017 and ensemble learning: 0.021 based on unseen test data) and largest values of coefficient of determination (adaptive boosting: 0.986 and ensemble learning: 0.983 based on unseen test data).…”
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Locally administered liposomal drug depot enhances rheumatoid arthritis treatment by inhibiting inflammation and promoting cartilage repair by Zongquan Zhang, Guan Wang, Zhuo Zhang, Xiaoya Liang, Guoshuang Wang, Maochang Xu, Xi Yang, Xiaolin Zhong, Chunhong Li, Meiling Zhou

“…Our findings provide a synergistic strategy for inhibiting inflammation and mitigating cartilage damage through local joint cavity injection, thereby enhancing the therapeutic efficacy of RA. Graphical Abstract…”
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The feasibility and safety of eustachian tube dilation with a standard endovascular balloon: a clinical pilot study by Valerie Dahm, Justin T. Lui, Soyeon Jung, Vincent Y. Lin, Joseph M. Chen, Trung N. Le

“…Trial registration The study was registered at clinicaltrials.gov; NCT04809753, initial release February 24th, 2021. Graphical Abstract…”
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Transdifferentiation of rat keratinocyte progenitors to corneal epithelial cells by limbal niche via the STAT3/PI3K/AKT signaling pathway by Bei Wang, Jiang-Lan Zhao, Gong-Yue Wang, Wan-Ying Cai, Yu-Ting Xiao, Jia-Song Wang, Chao Wang, Yu-Zhi Li, Xi Peng, Tian-Yu Yao, Ming-Chang Zhang, Hua-Tao Xie

“…Conclusions This study demonstrates the ability of LN to promote KPCs transdifferentiation into corneal epithelial cells in vitro, and this process is partially mediated by the STAT3/PI3K/AKT signaling pathway. Graphical abstract…”
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Internet of things enabled parking management system using long range wide area network for smart city by Waheb A. Jabbar, Lu Yi Tiew, Nadiah Y. Ali Shah

“…Users are provided with real-time updates on parking availability via the accessible AllThingsTalk Maker graphical user interface. Additionally, the system operates independently, sustained by a solar-powered rechargeable battery. …”
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Nitrogen source orchestrates pH modulation and secondary metabolism in Trichoderma harzianum by Stefania Vitale, Felice Salzano, Alessia Staropoli, Roberta Marra, David Turrà, Matteo Lorito, Francesco Vinale

“…This understanding provides new strategies for optimizing biocontrol formulations by manipulating nitrogen sources and pH conditions to enhance both fungal fitness and beneficial metabolite production. Graphical Abstract…”
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Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity by Boyuan Peng, Ziwei Li, Yong Cheng, Henghua Jiang, Qingsong Ye, Guangli Han

“…Conclusion This study highlights the potential of DPSC-IV as a novel preventive approach against orthodontic relapse, offering a novel strategy for maintaining long-term orthodontic stability. Graphical Abstract…”
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Sample size calculations based on day-to-day variability of stress biomarkers in persons with dementia and their family caregivers by Azita Emami, Jeehye Jun, Gabriella Engström, Lars Berglund, Töres Theorell

“…From this data, we created formulas and graphical tools for the number of required sampling days needed to detect effect differences, and we calculated number of days needed for regression coefficients to be estimated with<10% bias. …”
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