Pathologically altered articular cartilage attracts intense chondrocyte invasion into the extracellular matrix: in vitro pilot study by Victoria A. Shestakova, Ilya D. Klabukov, Ilya V. Kolobaev, Longfeng Rao, Dmitry A. Atiakshin, Michael A. Ignatyuk, Mikhail E. Krasheninnikov, Bagavdin G. Ahmedov, Sergey A. Ivanov, Peter V. Shegay, Andrey D. Kaprin, Denis S. Baranovskii

“…Conclusions Our preliminary results showed that human nasal chondrocytes are capable of infiltrating the pathologically altered extracellular matrix of articular cartilage damaged by arthritis, thereby promoting its repair to a physiologically relevant state. Graphical Abstract…”
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Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness by Oyku Ece Sumer, Korbinian Schelzig, Janine Jung, Xiaoya Li, Janina Moros, Luisa Schwarzmüller, Ezgi Sen, Sabine Karolus, Angelika Wörner, Verônica Rodrigues de Melo Costa, Nishanth Belugali Nataraj, Efstathios-Iason Vlachavas, Clarissa Gerhäuser, Karin Müller-Decker, Dominic Helm, Yosef Yarden, Birgitta Elisabeth Michels, Cindy Körner

“…The underlying mechanisms might inspire new therapeutic strategies aimed at shifting the balance towards tumor-suppressive miRNA species. Graphical Abstract…”
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MicroRNA-21 as a biomarker in terminal stage oral squamous cell carcinoma (OSCC) in the South Indian population by Chevuru Sai Shreya Reddy, Ashikha Shirin Usman P.P, Dhanraj M. Ganapathy, Ameya K.P., Durairaj Sekar

“…Level of expression of genes in both cancer cells and normal cells are also analysed using graphical method. Result: miR-21 secondary structure is predicted by applying mature sequence of miRNA. …”
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Surgical margins of the oral cavity: is 5 mm really necessary? by James Fowler, Yael Campanile, Andrew Warner, Francisco Laxague, Naif Fnais, Kevin Fung, Adrian Mendez, Danielle MacNeil, John Yoo, David Palma, Anthony Nichols

“…These findings require validation through multi-institutional collaborative efforts. Graphical abstract…”
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Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis by Mengling Wang, Feng Zeng, Fengling Ning, Yinhang Wang, Shilin Zhou, Jiaqi He, Cong Li, Cong Wang, Xiaolin Sun, Dongliang Zhang, Jisheng Xiao, Ping Hu, Svetlana Reilly, Hong Xin, Xudong Xu, Xuemei Zhang

“…This may provide another therapeutic option for renal fibrosis. Graphical Abstract…”
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Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis by Damien Veret, Gautier Tejedor, Esther Perez, Alison Chomette, Maylis Farno, Rosanna Ferreira-Lopez, Louis Dagneaux, Yves-Marie Pers, Christian Jorgsensen, Claire Gondeau, Jean-Marc Brondello

“…Conclusions Our findings suggest that the rapamycin and AD-MSC combination enhances the therapeutic efficacy of these cells in senescence-driven degenerative diseases such as OA, notably by improving their anti-fibrotic and anti-inflammatory properties. Graphical abstract…”
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Hepatoprotective potential of Chrysin in a rat model of isoniazid- and rifampicin-induced hepatic injury: suppression of matrix metalloproteinase and transforming growth factor β by Deepa Mandlik, Akhilesh Tokey, Rohit Lokhande, Yash Dagadu, Heena Choudhary, Satish Mandlik

“…Conclusions It is concluded that the CHY protects against INH + RFM-induced oxidative liver injury in rats. Graphical abstract…”
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Structural characterization and immunomodulatory activity of polysaccharides from the flowers of Imperata cylindrica Beauv.var. major (Nees) C.E.Hubb by Honglin He, Haijun Huang, Yunheng Yang, Yi Liu, Ailing Liang, Yao Lei, Chenghuai Tang, Ling Yao, Zhiwei Chen

“…Conclusions These findings provide useful evidence that support the development and potential clinical application of polysaccharides derived from the flowers of Imperata cylindrica. Graphical Abstract…”
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Exploring the potential of gemcitabine-metal–organic frameworks in combating pancreatic cancer under ketogenic conditions by Samira Nekoufar, Marjan Ghorbani, Sahar Safaei, Gholamreza Alinezhadi Khosroushahi, Farzad Izak Shirian, Behzad Baradaran, Masoumeh Tavakoli-Yaraki

“…Conclusion The use of metal–organic framework to encapsulate gemcitabine yielded notable pro-apoptotic effects in MIA-PaCa-2 cells with which ketogenic conditions had a synergistic effect that can hold promise for improving therapeutic options. Graphical Abstract…”
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Association between triglyceride-glucose-body mass index and risk of aortic stenosis progression in patients with non-severe aortic stenosis: a retrospective cohort study by Zhen Guo, Zhenyu Xiong, Lixiang He, Shaozhao Zhang, Xinghao Xu, Guanzhong Chen, Mengjie Xie, Wenjing Zhang, Ziwen Hui, Jiaying Li, Xinxue Liao, Xiaodong Zhuang

“…TyG-BMI index, as an effective alternative indicator of IR, can identify people at high risk of AS progression at an early stage of the disease, thereby improving the prognosis and reducing the socio-economic burden. Graphical abstract…”
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A smartphone application to objectively monitor music listening habits in adolescents by Danique E. Paping, Jantien L. Vroegop, Simone P. C. Koenraads, Carlijn M.P. le Clercq, André Goedegebure, Robert J. Baatenburg de Jong, Marc P. van der Schroeff

“…We consider a smartphone application to monitor listening habits of added value in future research investigating the possible damaging effects of PLDs on hearing acuity. Graphical abstract…”
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Exploring the application of knowledge transfer to sports video data by Shahrokh Heidari, Gibran Zazueta, Riki Mitchell, David Arturo Soriano Valdez, Mitchell Rogers, Mitchell Rogers, Jiaxuan Wang, Ruigeng Wang, Marcel Noronha, Alfonso Gastelum Strozzi, Mengjie Zhang, Patrice Jean Delmas, Patrice Jean Delmas

“…The application of Artificial Intelligence (AI) and Computer Vision (CV) in sports has generated significant interest in enhancing viewer experience through graphical overlays and predictive analytics, as well as providing valuable insights to coaches. …”
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Associations between heavy metal exposure and vascular age: a large cross-sectional study by Yuntao Feng, Chengxing Liu, Litang Huang, Jun Qian, Na Li, Hongwei Tan, Xuebo Liu

“…Further research is needed to validate these findings and to develop more precise public health strategies targeting environmental risks. Graphical Abstract…”
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International perspective on healthcare provider gender bias in musculoskeletal pain management: a scoping review protocol by Katherine Fisher Wilford, Maria Jesus Mena-Iturriaga, Margaret Vugrin, Macarena Wainer, Phillip S Sizer, Gesine Hendrijke Seeber

“…Additionally, results will be presented in tabular and graphical form.Ethics and dissemination As this study will neither involve human subject participation nor utilisation of protected data, ethical approval is not required. …”
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In vitro high-throughput screening of the antimicrobial activity of different compounds against Xylella fastidiosa subsp. pauca by Carmine Del Grosso, Luca Grandi, Tommaso Lombardi, Giusy D’Attoma, Nicolas Schmitt, Vito Rocco De Michele, Maria Saponari

“…The methodologies described proved to be useful for profiling the antimicrobial activity of a large panel of compounds and the data collected provide evidence of their in vitro effectiveness. Graphical Abstract…”
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Comparative analysis of real-world data on the efficacy and safety of and adherence to ICS/LABA combinations in asthma management by Hee Sun Park, Jungkuk Lee, Hasung Kim, Seong-Dae Woo

“…These results provide valuable insights for clinicians in selecting appropriate and individually tailored inhaler therapies in real-world settings. Graphical abstract…”
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Changes in Corneal Parameters after DMEK Surgery: A Swept-Source Imaging Analysis at 12-Month Follow-Up Time by Anna Machalińska, Agnieszka Kuligowska, Karolina Kaleta, Monika Kuśmierz-Wojtasik, Krzysztof Safranow

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Energy transfer aspects of chemically reactive Casson fluid between a conical gap of cone-disk system with multiple rotations by M. Qamar, M. Khan, A.S. Alqahtani, M.Y. Malik

“…The influence of physical factors like velocity, temperature, concentration, drag friction, heat transportation rate, and Sherwood number are explored theoretically and graphically. We have found that radial velocity profile across three models improved with an increment in the Casson fluid factor. …”
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Decision tree-based learning and laboratory data mining: an efficient approach to amebiasis testing by Enas Al-khlifeh, Ahmad S. Tarawneh, Khalid Almohammadi, Malek Alrashidi, Ramadan Hassanat, Ahmad B. Hassanat

“…This finding significantly contributes to the emerging use of ML as a decision support system in parasitic disease diagnosis. Graphical Abstract…”
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Interaction between biochar particle size and soil salinity levels on soil properties and tomato yield by Zhuqing Wu, Yaqiong Fan, Zhengquan Zhou, Xinmei Hao, Shaozhong Kang

“…Small particle size biochar boosted tomato yield in soils without salinity stress. Graphical Abstract…”
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