Analysis of water based Casson hybrid nanofluid (NiZnFe2O4+MnZnFe2O4) flow over an electromagnetic actuator with Cattaneo–Christov heat-mass flux: A modified Buongiorno model by S. Baskaran, R. Sowrirajan, S. Divya, S. Eswaramoorthi, K. Loganathan

“…The implication of key parameters on both direction velocities, temperature, nanofluid concentration, skin friction coefficients, local Nusselt number, and Sherwood number are displayed graphically. Our investigation revealed that fluid velocities are suppressed by increasing the values of Forchheimer number. …”
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Metabolomic and transcriptomic analyses revealed potential mechanisms of Anchusa italica Retz. in alleviating cerebral ischemia–reperfusion injury via Wnt/β-catenin pathway modulat... by Wenta Tan, Shuo Fu, Yufei Wang, Bojun Hu, Guiquan Ding, Li Zhang, Wen Zhang, Guanhua Du, Junke Song

“…By restoring the balance of mitochondrial function and energy metabolism, AIRE might offer a potentially therapeutic strategy for addressing CIRI. Graphical Abstract…”
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Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA by Ming-Chin Lan, Stanley Yung-Chuan Liu, Ming-Ying Lan, Yun-Chen Huang, Tung-Tsun Huang, Yen-Bin Hsu

“…Therefore, further treatment modalities should address the distinct anatomical trait between positional and non-positional OSA. Graphical abstract…”
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A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management by Josee Paradis, Agnieszka Dzioba, Hamdy El-Hakim, Paul Hong, Frederick K. Kozak, Lily H. P. Nguyen, Demitri Perera, Evan Jon Propst, Jennifer M. Siu, Monika Wojtera, Murad Husein, National Choanal Atresia Study Working Group

“…The optimal surgical approach, age at surgical repair, use of stents, surgical adjuncts, and need for planned second look warrant further investigation. Graphical abstract…”
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MetaboLINK is a novel algorithm for unveiling cell-specific metabolic pathways in longitudinal datasets by Jared Lichtarge, Gerarda Cappuccio, Gerarda Cappuccio, Soumya Pati, Soumya Pati, Alfred Kwabena Dei-Ampeh, Alfred Kwabena Dei-Ampeh, Senghong Sing, Senghong Sing, Senghong Sing, LiHua Ma, Zhandong Liu, Zhandong Liu, Mirjana Maletic-Savatic, Mirjana Maletic-Savatic, Mirjana Maletic-Savatic

“…As biological datasets, particularly metabolomics, become larger and more complex, innovative strategies are essential for deciphering the intricate molecular and cellular networks.MethodsWe introduce a pioneering analytical approach that combines Principal Component Analysis (PCA) with Graphical Lasso (GLASSO). This method is designed to reduce the dimensionality of large datasets while preserving significant variance. …”
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Platycodon grandiflorum-derived extracellular vesicles suppress triple-negative breast cancer growth by reversing the immunosuppressive tumor microenvironment and modulating the gu... by Min Yang, Jia Guo, Jinxian Li, Shuyue Wang, Yuan Sun, Ying Liu, Yinghua Peng

“…In conclusion, these findings highlight PGEVs as a promising natural, biocompatible and efficient nanotherapeutic candidate for treating TNBC. Graphical Abstract…”
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Pan-cancer analysis shows that TNFSF4 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including liver cancer by Zhaoda Deng, Lincheng Li, Zihe Meng, Guineng Zeng, Rui Cao, Rong Liu

“…Our study shows that TNFSF4 is a promising prognostic and immunotherapeutic biomarker in some malignant tumors. Graphical Abstract…”
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PLGA confers upon conventional nonfluorescent molecules luminescent properties to trigger 1O2-induced pyroptosis and immune response in tumors by Lan Zou, Rujing Wang, Mengnan Zhao, Yuke Li, Chen Sun, Jinjin Xie, Yan Chen, Qian Jing, Dandan Mi, Sanjun Shi

“…This discovery holds the potential to facilitate the application of light-controlled pyroptosis in antitumor therapy, marking a promising stride toward innovative approaches in cancer treatment. Graphical abstract…”
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An Architecture-Tracking Approach to Evaluate a Modular and Extensible Flight Software for CubeSat Nanosatellites by Carlos E. Gonzalez, Camilo J. Rojas, Alexandre Bergel, Marcos A. Diaz

“…We also present an <italic>architecture tracking methodology</italic> to verify and control the flight software quality criteria during the development process through the use of <italic>graphical software analysis tools</italic> and agile programming techniques. …”
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Predictive value of preoperative pan-immune-inflammation value index in the prognosis of oral cancer patients undergoing radical resection by Weihai Huang, Yulan Lin, Enling Xu, Yanmei Ji, Jing Wang, Fengqiong Liu, Fa Chen, Yu Qiu, Bin Shi, Lisong Lin, Baochang He

“…Conclusions PIV is an independent predictor of prognosis in patients with oral squamous cell carcinoma, and a column-line graphical model based on PIV can effectively predict prognosis.…”
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First evidence of the effectiveness of a field application of RNAi technology in reducing infestation of the mite Varroa destructor in the western honey bee (Apis mellifera) by Francesca Bortolin, Emanuele Rigato, Sergio Perandin, Anna Granato, Laura Zulian, Caterina Millino, Beniamina Pacchioni, Franco Mutinelli, Giuseppe Fusco

“…This study supports the potential of RNAi as a promising alternative to chemical pesticides, offering a targeted, efficient and sustainable solution for managing V. destructor in honey bee populations. Graphical Abstract…”
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Extracellular vesicle surface engineering with integrins (ITGAL & ITGB2) to specifically target ICAM-1-expressing endothelial cells by Markus Bergqvist, Kyong-Su Park, Nasibeh Karimi, Lijuan Yu, Cecilia Lässer, Jan Lötvall

“…We conclude that LFA-1-expressing EVMyd88 may be a candidate suitable for delivering therapeutic peptides in inflammatory diseases associated with TLR-activation. Graphical Abstract…”
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Simultaneously delivery of functional gallium ions and hydrogen sulfide to endow potentiated treatment efficacy in chemo- and PARPi-resistant ovarian cancer by Sangsang Tang, Yangyang Li, Yifeng Fang, Mengyan Tu, Shenglong Wu, Yixuan Cen, Junfen Xu

“…Altogether, our results demonstrated a potentially safe and practical strategy by using Ga2S3-BSA NMs to combat drug resistance in platinum-resistant OC. Graphical Abstract…”
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Exploiting venom toxins in paratransgenesis to prevent mosquito-borne disease by Stephanie French, Rachael Da Silva, Janet Storm, Christida E. Wastika, India Cullen, Martijn ten Have, Grant L. Hughes, Cassandra M. Modahl

“…We postulate the potential to apply this principle to target arboviruses using antiviral toxin effectors. Graphical Abstract…”
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Entropy analysis of Darcy–Forchheimer flow of couple-stress TiO2-CoFe2O4/engine oil based hybrid nanofluid between two rotating disks considering hall effect by Sk Enamul, Seetalsmita Samal, Surender Ontela

“…Critical parameters such as the inertial coefficient, heat source parameter, nanoparticle concentration, and magnetic field parameter are analyzed graphically. These analyses explore their effects on velocity profiles, temperature distribution, and entropy generation. …”
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Interdependence Between River Aquifer Groundwater Flow and Temperature–Depth Profiles: Type Curves Based on Pi Theorem and Numerical Simulations by José Antonio Jiménez-Valera, Iván Alhama, Carlos Duque, David Labat

“…Experimental studies and numerical modeling have supported analytical solutions; these solutions have been proposed for specific cases in which the aim has been to understand discharge/recharge and aquifer characterization. In this study, new graphical solutions or type curves are provided to estimate the subsurface flow and thermal–mechanical parameters in anisotropic porous media. …”
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Targeting OAS3 for reversing M2d infiltration and restoring anti-tumor immunity in pancreatic cancer by Shaopeng Zhang, Ximo Xu, Kundong Zhang, Changzheng Lei, Yitian Xu, Pengshan Zhang, Yuan Zhang, Haitao Gu, Chen Huang, Zhengjun Qiu

“…In conclusion, OAS3 presents as a promising immune therapeutic target for reversing IL-10highVEGF-AhighM2d infiltration and restoring CD8+T cell-mediated anti-tumor immunity in pancreatic cancer. Graphical abstract…”
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Novel numerical and artificial neural computing with experimental validation towards unsteady micropolar nanofluid flow across a Riga plate by Muhammad Bilal, F. Maiz, Muhammad Farooq, Hijaz Ahmad, Mohammad Khalid Nasrat, Hassan Ali Ghazwani

“…The influence of physical constraints on the dimensionless temperature, concentration, microrotation, and velocity distributions are graphically displayed and discussed. Numerical results for skin friction, Sherwood, and Nusselt numbers are presented in tabular form. …”
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Modeling saturation exponent of underground hydrocarbon reservoirs using robust machine learning methods by Abhinav Kumar, Paul Rodrigues, A. K. Kareem, Tingneyuc Sekac, Sherzod Abdullaev, Jasgurpreet Singh Chohan, R. Manjunatha, Kumar Rethik, Shivakrishna Dasi, Mahmood Kiani

“…The sensitivity analysis indicates that resistivity index and true resistivity have direct correlation with the saturation exponent while porosity, absolute permeability and water saturation is inversely related with saturation exponent. In addition, the graphical-based and statistical-based evaluations illustrate that AdaBoost and ensemble learning models outperforms all other developed data-driven intelligent models as these two models are associated with lowest values of mean square error (adaptive boosting: 0.017 and ensemble learning: 0.021 based on unseen test data) and largest values of coefficient of determination (adaptive boosting: 0.986 and ensemble learning: 0.983 based on unseen test data).…”
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Locally administered liposomal drug depot enhances rheumatoid arthritis treatment by inhibiting inflammation and promoting cartilage repair by Zongquan Zhang, Guan Wang, Zhuo Zhang, Xiaoya Liang, Guoshuang Wang, Maochang Xu, Xi Yang, Xiaolin Zhong, Chunhong Li, Meiling Zhou

“…Our findings provide a synergistic strategy for inhibiting inflammation and mitigating cartilage damage through local joint cavity injection, thereby enhancing the therapeutic efficacy of RA. Graphical Abstract…”
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