Chaihu Shugan San and Zuogui Yin synergistically improve premature ovarian failure in a rat model via the PI3K/Akt/mTOR pathway by Fei Zhang, RuiFang Liu, ZhenLing Xu, WenJie Chen, XiYa Lu, Yang Wang

“…Key outcomes, including ovarian granulosa cell proliferation, follicular integrity, and hormonal levels (FSH and E2), were assessed. …”
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Research progress in the correlation between chronic stress and ovarian dysfunction by WEI Liutong, LAI Dongmei

“…Recent studies have shown that chronic stress affects the hypothalamic-pituitary-ovary axis directly or indirectly and leads to ovarian dysfunction-including excessive activation of primordial follicles, a reduction in preantral and preovulatory follicles, decline of oocyte quality, and granulosa cell apoptosis, through corticotropin-releasing hormone, corticosterone and cortisol secreted by the hypothalamic-pituitary-adrenal axis, as well as epinephrine and norepinephrine released by the sympathetic-adrenal-medullary axis and sympathetic nervous system. …”
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Intraoperative Diagnosis: Imprint Cytology and Frozen Section in Ovarian Tumor, Averting Additional Surgery by Kiran Lanjewar, Sanjay Deotale, Sunita Vagha, Sudhanshu Dakre

“…A granulosa cell tumor (GCT) is a type of ovarian cancer that constitutes approximately 10% of all ovarian malignancies. …”
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Physiological premature aging of ovarian blood vessels leads to decline in fertility in middle-aged mice by Lu Mu, Ge Wang, Xuebing Yang, Jing Liang, Huan Tong, Lingyu Li, Kaiying Geng, Yingnan Bo, Xindi Hu, Ruobing Yang, Xueqiang Xu, Yan Zhang, Hua Zhang

“…Utilizing genetic-modified mouse models, we demonstrate that granulosa cell secreted VEGFA governs ovarian angiogenesis, but the physiological decline in oBV is not attributed to VEGFA insufficiency. …”
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Cloning, Characterization and Expression Pattern of the Ovarian Cytochrome P450 Cyp19a1aGene in Gonadal Developmental Period of Cobaltcap Silverside Hypoatherina tsurugae by Dilip Kumar Bej

“…The upregulation of the cyp19a1a transcription factor is required for granulosa cell differentiation and ovarian maintenance. 1630 bp of cyp19a1 mRNA transcript of Hypoatherina tsurugae was cloned and sequenced. …”
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Spatiotemporal dynamics of early oogenesis in pigs by Wei Ge, Yi-Lin Niu, Yu-Kang Li, Li Li, Han Wang, Wen-Wen Li, Tian Qiao, Yan-Ni Feng, Yu-Qing Feng, Jing Liu, Jun-Jie Wang, Xiao-Feng Sun, Shun-Feng Cheng, Lan Li, Wei Shen

“…RNA velocity analysis with ST identifies the molecular characteristics and spatial dynamics of granulosa cell lineages originating from the cortical and medullary regions in pig ovaries. …”
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Quantitative Proteomics Analysis Reveals XDH Related with Ovarian Oxidative Stress Involved in Broodiness of Geese by Ning Zhou, Yaoyao Zhang, Youluan Jiang, Wang Gu, Shuai Zhao, Wanwipa Vongsangnak, Yang Zhang, Qi Xu, Yu Zhang

“…The results of this study showed that during the broody period, geese exhibited degraded ovarian tissues, disrupted follicular development, a thinner granulosa cell layer, and lower levels of ovarian hormones E2, P4, and AMH. …”
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Increased susceptibility to diet-induced obesity in female mice impairs ovarian steroidogenesis: The role of elevated leptin signalling on nodal activity inhibition in theca cells by Karolina Wołodko, Tjaša Šentjurc, Edyta Walewska, Elżbieta Laniecka, Magdalena Jura, António Galvão

“…Following the characterisation of the mouse phenotype, gonadal fat (GON), whole ovaries (WO), ovarian TC and granulosa cell (GC) fractions were collected for mRNA transcription and protein expression analysis. …”
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