Understanding Nigeria’s antibiotic resistance crisis among neonates and its future implications by Victor Oluwatomiwa Ajekiigbe, Ikponmwosa Jude Ogieuhi, Temiloluwa Adebayo Odeniyi, Praise Oluwatobi Ogunleke, Josiah Temitope Olatunde, Adedoyin Veronica Babalola, Akintunde Abisoye Omoleke, Tolulope Felix Omitade, Damilare Emmanuel Olakanmi, Adewunmi Akingbola, Chidera Stanley Anthony

“…There has been an increasing prevalence of sepsis among newborns primarily due to Gram-negative bacteria, which highlights the urgency and need to be addressed. …”
Get full text

Microbial Quality of Sliced Pawpaw (Carica papaya) and Watermelon (Citrullus lanatus) Sold on Some Streets of Accra Metropolis, Ghana by Michael Olu-Taiwo, Baakwa Miah De-Graft, Akua Obeng Forson

“…Sliced watermelons and pawpaws were randomly purchased from selected suburbs in Greater Accra Region of Ghana. One gram (1 g) of each watermelon and pawpaw was homogenized in 9 ml of sterile peptone water, and 0.1 ml from each serial dilutions of each fruit was spread on plate count agar, blood agar, and MacConkey agar plates for total aerobic counts and coliform counts. …”
Get full text

Identification and prioritization of novel therapeutic candidates against glutamate racemase from Klebsiella pneumoniae. by Ankit Kumar, Farah Anjum, Md Imtaiyaz Hassan, Anas Shamsi, Rashmi Prabha Singh

“…<h4>Background</h4>Klebsiella pneumoniae, a gram-negative bacterium in the Enterobacteriaceae family, is non-motile, encapsulated, and a major cause of nosocomial infections, particularly in intensive care units. …”
Get full text

The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper by H Finlayson, V Chibabhai, P Jeena, S Kolman, W Lowman, T C Manzini, T Nana, J Nuttall, A Parker, P Skosana, V Ueckermann, A Wise

“…It is increasing in both the public and private healthcare sectors within South Africa, especially in Gram-negative organisms, and is associated with increased use of World Health Organization watch and reserve antibiotics. …”
Get full text

Intra-uterine Growth Restriction Downregulates the Hepatic Toll Like Receptor-4 Expression and Function by Ozlem Equils, Sapna Singh, Semra Karaburun, Daning Lu, Manikkavasagar Thamotharan, Sherin U. Devaskar

“…We propose that IUGR dysregulates TLR4 expression and function in the offspring, which may help explain the increased risk of Gram-negative sepsis and inflammatory diseases in this population.…”
Get full text

The effect of granulated sugar application on healing in the treatment of infected wounds and abscesses by Nuri Yavru, Yılmaz Koç, Mustafa Ancan, Yusuf Doğruer

“…From the other 3 dogs 1 gram of muscle piece was taken before and third and sixth day after the treatment in order to detect the bacteria level on both of the wounds, that colony counts were made.…”
Get full text

Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives by Domenica Lucia D’Antonio, Anna Zenoniani, Samia Umme, Adriano Piattelli, Maria Cristina Curia

“…<i>Fusobacterium nucleatum (Fn)</i>, an anaerobic Gram-negative bacterium primarily residing in the oral cavity, has garnered significant attention for its emerging role in several extra-oral human diseases and, lately, in pancreatic cancer progression and prognosis. …”
Get full text

Development of a Magnetic LED-based Sterilisator for Inactivation of Contaminant Bacteria by Yonatan ., Suryani Dyah Astuti, Khusnul Ain, Deny Arifianto, Ahmad Khalil Yaqubi, Perwira Annissa Dyah Permatasari

“…This study aims to evaluate combining a static magnetic field with photodynamic inactivation to the inactivation of S. aureus (a Gram-positive bacterium). The research utilized high-power blue LEDs and static magnetic fields generated by neodymium magnets. …”
Get full text

Isolation and Identification of Lipase-producing Actinobacteria from the Lut Desert of Iran by Samira Abedi-Dolatabadi, Moj Khaleghi, Sedigheh Ghasemzadeh, Azadeh Lohrasbi-Nejad, Arastoo Badoei Delfard

“…Actinobacteria, which are Gram-positive bacteria, have the largest genome size among bacteria and produce various secondary metabolites, including enzymes. …”
Get full text

Invasive Aspergillus niger Is the Sole Etiological Agent for CSOM : A Clinical Case from Nepal by Ajay Kumar Chaurasiya, Rabindra Bhakta Pradhananga, Niranjan Prasad Sah, Basista Prasad Rijal, Bharat Mani Pokhrel, Santosh Dulal

“…Findings of laboratory analysis indicated that Gram staining of aural discharge displayed pus cells with fungal spores but did not exhibit bacteria. …”
Get full text

Recognition of Staphylococcus aureus by the pattern recognition molecules langerin, mannan-binding lectin, and surfactant protein D: the influence of capsular polysaccharides and w... by Kirstine Mejlstrup Hymøller, Kirstine Mejlstrup Hymøller, Stig Hill Christiansen, Stig Hill Christiansen, Anders Grønnegaard Schlosser, Uffe B. Skov Sørensen, Jean C. Lee, Steffen Thiel, Steffen Thiel

“…We have investigated their interaction with the Gram-positive opportunistic pathogen Staphylococcus aureus, a bacterium whose cell wall contains two key glycopolymers: capsular polysaccharide (CP) and wall teichoic acid (WTA). …”
Get full text

Molecular Detection of Anaplasma phagocytophilum in Small Mammals and Infesting Ticks in Laikipia County, Kenya by Erick Titus Mosha, Joseph K. N. Kuria, Moses Otiende, Isaac Lekolool

“…These are sub-microscopic, Gram-negative, obligate intracellular pathogens that infect both vertebrate and invertebrate hosts. …”
Get full text

Complete genome sequencing and probiotic characterization of promising lactic acid bacterial strains isolated from dairy products in Egyptian markets by Mostafa F. El-Hosseny, Mohamed G Seadawy, Mohammed O Abdel-Monem, Mervat G Hassan

“…The antibiotic sensitivity test was performed later to the antimicrobial assessment against widespread both negative and positive gram-stained bacteria infecting humans, along with the antiviral evaluation against (SARS-CoV-2), the virus that has disturbed the world recently. …”
Get full text

4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation by Ying Gu, Hsi-Ming Lee, Nicole Napolitano, McKenzie Clemens, Yazhou Zhang, Timo Sorsa, Yu Zhang, Francis Johnson, Lorne M. Golub

“…Endotoxin (lipopolysaccharide, LPS), derived from gram-negative periodonto-pathogens, can induce the local accumulation of mononuclear cells in the inflammatory lesion, increasing proinflammatory cytokines and matrix metalloproteinases (MMPs). …”
Get full text

The Association between Abnormal Vaginal Flora and Cytological Evidence of HPV with Prematurity in High-Risk Pregnant Women by Alana Dantas Freire, Ada Isa Custódio, José Queiroz Filho, Janaína Crispim Freitas, Ana Katherine Gonçalves, Ricardo Ney Cobucci

“…Vaginal specimens were collected to obtain material from the upper lateral vaginal vault and cervix for direct microscopic examination of vaginal contents and preparation of Gram-stained and pap smear slides. Potential determinants of infection were assessed using the chi-square test. …”
Get full text

<i>Vibrio vulnificus</i>—A Review with a Special Focus on Sepsis by Marcello Candelli, Marta Sacco Fernandez, Cristina Triunfo, Andrea Piccioni, Veronica Ojetti, Francesco Franceschi, Giulia Pignataro

“…<i>Vibrio vulnificus</i> (<i>V. vulnificus</i>) is a Gram-negative, halophilic bacillus known for causing severe infections such as gastroenteritis, necrotizing fasciitis, and septic shock, with mortality rates exceeding 50% in high-risk individuals. …”
Get full text

Predisposing Factors, Microbial Characteristics, and Clinical Outcome of Microbial Keratitis in a Tertiary Centre in Hong Kong: A 10-Year Experience by Alex Lap-Ki Ng, Kelvin Kai-Wang To, Chile Chi-Lai Choi, Leonard Hsu Yuen, Suk-Ming Yim, Keith Shun-Kit Chan, Jimmy Shiu-Ming Lai, Ian Yat-Hin Wong

“…Fluoroquinolone susceptibility was tested in 47 Gram-negative bacteria with 93.6% susceptibility (100% for Pseudomonas). 90.7% of cases had good visual outcome. …”
Get full text

Risk Factors for Acute Hemorrhagic Rectal Ulcer Syndrome and Its Prognosis: A Density Case-Control Study by Toshihiko Komai, Fumio Omata, Yasutoshi Shiratori, Daiki Kobayashi, Hiroko Arioka

“…Multivariate logistic regression analyses revealed that the significant adjusted odds ratio (95% confidence interval) of hospitalization, antithrombotic drug use, and one gram increase of serum albumin was 15.7 (2.25–108.9), 12.1 (1.53–94.4), and 0.11 (0.02–0.52), respectively. …”
Get full text

Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae by Lisa Zierke, Rodi Mourad, Thomas P. Kohler, Mathias Müsken, Sven Hammerschmidt

“…Klebsiella pneumoniae, a Gram-negative human pathogen associated with high antimicrobial resistances, produces 77 CPS serotypes. …”
Get full text

Virgin coconut oil lessens trichloroacetic acid assault on the stomach and intestine of rats via enhancement of Nrf2 but inhibition of TNF-α, IL1β/NF-kB signalling pathway by OO Oladokun, KO Ajeigbe, MA Adelakun

“…Materials and Methods: Rats received TCA (250 mg/Kg b.wt, p.o) for ten days, followed by either 5 % or 10 % VCO per gram feed alone or in combination with 5FU (50 mg/kg, i.p) for another ten days. …”
Get full text