The Efficacy and Safety of the Chinese Herbal Formula, JTTZ, for the Treatment of Type 2 Diabetes with Obesity and Hyperlipidemia: A Multicenter Randomized, Positive-Controlled, Op... by Xiaotong Yu, Lipeng Xu, Qiang Zhou, Shengping Wu, Jiaxing Tian, Chunli Piao, Hailong Guo, Jun Zhang, Liping Li, Shentao Wu, Meizhen Guo, Yuzhi Hong, Weirong Pu, Xiyan Zhao, Yang Liu, Bing Pang, Zhiping Peng, Song Wang, Fengmei Lian, Xiaolin Tong

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Leptin decreases Th17/Treg ratio to facilitate neuroblastoma via inhibiting long-chain fatty acid catabolism in tumor cells by Meng Li, Di Li, Hai-Yun Wang, Weixin Zhang, Zhenjian Zhuo, Huiqin Guo, Jiabin Liu, Yue Zhuo, Jue Tang, Jing He, Lei Miao

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Two Novel Compounds Isolated from the Marine Fungal Symbiont of Aspergillus unguis Induce Apoptosis and Cell Cycle Arrest in Breast Cancer Cells: In vitro Study by Bashari MH, Agung MUK, Ariyanto EF, Al Muqarrabun LMR, Salsabila S, Chahyadi A, Rosandy AR, Afifah E, Afni M, Atmaja HE, Putri T, Utami F, Subhan B, Syafrizayanti, Andriani Y, Elfahmi

“…Muhammad Hasan Bashari,1 Mochamad Untung Kurnia Agung,2 Eko Fuji Ariyanto,1 Laode Muhammad Ramadhan Al Muqarrabun,3 Syefira Salsabila,3 Agus Chahyadi,3 Andi Rifki Rosandy,3 Ervi Afifah,4 Merry Afni,5 Harold Eka Atmaja,5 Tenny Putri,5 Fitria Utami,5 Beginer Subhan,6 Syafrizayanti,7 Yosie Andriani,8 Elfahmi3,9 1Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Department of Marine Science, Faculty of Fisheries and Marine Science, Universitas Padjadjaran, Bandung, West Java, Indonesia; 3University Center of Excellence for Nutraceuticals, Bioscience and Biotechnology Research Center, Bandung Institute of Technology, Bandung, West Java, Indonesia; 4Graduate School of Master Program, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; 5Biomedical Laboratory, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 6Department of Marine Science and Technology, Faculty of Fisheries and Marine Science, IPB University, Bogor, West Java, Indonesia; 7Biochemistry Laboratory, Department of Chemistry, Universitas Andalas, Padang, West Sumatera, Indonesia; 8Institute of Climate Adaptation and Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Nerus, Terengganu, Malaysia; 9School of Pharmacy, Bandung Institute of Technology, Bandung, West Java, IndonesiaCorrespondence: Muhammad Hasan Bashari, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, 40161, West Java, Indonesia, Email bashari@unpad.ac.id Elfahmi, School of Pharmacy, Bandung Institute of Technology, Bandung, West Java, Indonesia, Email elfahmi@fa.itb.ac.idPurpose: A promising feature of marine sponges is the potential anticancer efficacy of their secondary metabolites. …”
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Disparities in the uptake of HPV-related cancer prevention strategies among women by HIV status in Puerto Rico by Marievelisse Soto-Salgado, Melisa Ramos-Sepúlveda, Jeslie M. Ramos-Cartagena, Maribel Tirado-Gómez, Humberto M. Guiot, Cristina Muñoz-Masso, Lorena González-Sepúlveda, Ana Patricia Ortiz

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The efficacy and safety of first-line monotherapies in primary therapy of invasive aspergillosis: a systematic review by Yan Chen, Yan Chen, Jiaojiao Zhao, Jiaojiao Zhao, Yifei Wang, Yifei Wang, Long Ge, Long Ge, Joey Sum-wing Kwong, Junjie Lan, Rui Zhang, Huaye Zhao, Linfang Hu, Jiaxue Wang, Shuimei Sun, Songsong Tan, Xiaoqing Lin, Rui He, Wenyi Zheng, Xiaosi Li, Jiaxing Zhang

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Recent methane surges reveal heightened emissions from tropical inundated areas by Xin Lin, Shushi Peng, Philippe Ciais, Didier Hauglustaine, Xin Lan, Gang Liu, Michel Ramonet, Yi Xi, Yi Yin, Zhen Zhang, Hartmut Bösch, Philippe Bousquet, Frédéric Chevallier, Bogang Dong, Cynthia Gerlein-Safdi, Santanu Halder, Robert J. Parker, Benjamin Poulter, Tianjiao Pu, Marine Remaud, Alexandra Runge, Marielle Saunois, Rona L. Thompson, Yukio Yoshida, Bo Zheng

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Identification of as a Susceptibility Locus for Kawasaki Disease in Patients Younger than 6 Months of Age by Hea-Ji Kim, Sin Weon Yun, Jeong Jin Yu, Kyung Lim Yoon, Kyung-Yil Lee, Hong-Ryang Kil, Gi Beom Kim, Myung-Ki Han, Min Seob Song, Hyoung Doo Lee, Kee Soo Ha, Sejung Sohn, Ryota Ebata, Hiromichi Hamada, Hiroyuki Suzuki, Yoichiro Kamatani, Michiaki Kubo, Kaoru Ito, Yoshihiro Onouchi, Young Mi Hong, Gi Young Jang, Jong-Keuk Lee

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A machine learning model to predict neurological deterioration after mild traumatic brain injury in older adults by Daisu Abe, Motoki Inaji, Takeshi Hase, Eiichi Suehiro, Naoto Shiomi, Hiroshi Yatsushige, Shin Hirota, Shu Hasegawa, Hiroshi Karibe, Akihiro Miyata, Kenya Kawakita, Kohei Haji, Hideo Aihara, Shoji Yokobori, Takeshi Maeda, Takahiro Onuki, Kotaro Oshio, Nobukazu Komoribayashi, Michiyasu Suzuki, Taketoshi Maehara

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Optimal timing of organs-at-risk-sparing adaptive radiation therapy for head-and-neck cancer under re-planning resource constraints by Fatemeh Nosrat, Cem Dede, Lucas B. McCullum, Raul Garcia, Abdallah S.R. Mohamed, Jacob G. Scott, James E. Bates, Brigid A. McDonald, Kareem A. Wahid, Mohamed A. Naser, Renjie He, Aysenur Karagoz, Amy C. Moreno, Lisanne V. van Dijk, Kristy K. Brock, Jolien Heukelom, Seyedmohammadhossein Hosseinian, Mehdi Hemmati, Andrew J. Schaefer, Clifton D. Fuller

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Efficacy and safety of everolimus for patients with focal cortical dysplasia type 2 by Se Hee Kim, Hoon‐Chul Kang, Yun Ho Roh, Jongsung Hahn, Kyung Lok Min, Seok‐Jin Lee, Donghwa Yang, Han Som Choi, Soyoung Park, Jeong Ho Lee, Sang‐Guk Lee, Se Hoon Kim, Min Jung Chang, Heung Dong Kim

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Neoadjuvant chemoradiotherapy up-regulates PD-L1 in radioresistant colorectal cancer by Sung Uk Bae, Hye Won Lee, Jee Young Park, Incheol Seo, Jae-Min Cho, Jin Young Kim, Ju Yup Lee, Yoo Jin Lee, Seong Kyu Baek, Nam Kyu Kim, Sang Jun Byun, Shin Kim

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Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms by Shivan Sivakumar, Ashwin Jainarayanan, Edward Arbe-Barnes, Piyush Kumar Sharma, Maire Ni Leathlobhair, Sakina Amin, David J. Reiss, Lara Heij, Samarth Hegde, Assaf Magen, Felicia Tucci, Bo Sun, Shihong Wu, Nithishwer Mouroug Anand, Hubert Slawinski, Santiago Revale, Isar Nassiri, Jonathon Webber, Gerard D. Hoeltzel, Adam E. Frampton, Georg Wiltberger, Ulf Neumann, Philip Charlton, Laura Spiers, Tim Elliott, Maria Wang, Suzana Couto, Thomas Lila, Pallavur V. Sivakumar, Alexander V. Ratushny, Mark R. Middleton, Dimitra Peppa, Benjamin Fairfax, Miriam Merad, Michael L. Dustin, Enas Abu-Shah, Rachael Bashford-Rogers

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Clinical Significance of Perioperative Minimal Residual Disease Detected by Circulating Tumor DNA in Patients With Lung Cancer With a Long Follow-up Data: An Exploratory Study by Shuta Ohara, MD, PhD, Kenichi Suda, MD, PhD, Sumedha Sudhaman, PhD, Akira Hamada, MD, PhD, Masato Chiba, MD, PhD, Masaki Shimoji, MD, PhD, Toshiki Takemoto, MD, PhD, Ekaterina Kalashnikova, PhD, Samantha K. Cheung, PhD, Michael Krainock, MD, PhD, Jordan Feeney, BS, Himanshu Sethi, MPH, Minetta C. Liu, MD, Junichi Soh, MD, PhD, Yasuhiro Tsutani, MD, PhD, Tetsuya Mitsudomi, MD, PhD

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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

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Evaluation of karamunting Melastoma malabathricum L leaf extract on gonad development and growth performance of tilapia Oreochromis niloticus by Ermianus Samalei, Muhammad Zairin Jr., Odang Carman, Muhammad Agus Suprayudi

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Association between solid cooking fuels exposure and metabolic syndrome: Evidence from China by Jiaming Xue, Shuai Chen, Yicheng Jiang, Qi Liu, Yu Wang, Yuwen Jiao, Yuancheng Shao, Jie Zhao, Yan Zhou, Dongmei Wang, Liming Tang

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Dynamic Imprints of Colliding-wind Dust Formation from WR 140 by Emma P. Lieb, Ryan M. Lau, Jennifer L. Hoffman, Michael F. Corcoran, Macarena Garcia Marin, Theodore R. Gull, Kenji Hamaguchi, Yinuo Han, Matthew J. Hankins, Olivia C. Jones, Thomas I. Madura, Sergey V. Marchenko, Hideo Matsuhara, Florentin Millour, Anthony F. J. Moffat, Mark R. Morris, Patrick W. Morris, Takashi Onaka, Marshall D. Perrin, Armin Rest, Noel Richardson, Christopher M. P. Russell, Joel Sanchez-Bermudez, Anthony Soulain, Peter Tuthill, Gerd Weigelt, Peredur M. Williams

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Psychometric properties of the Moroccan dialect versions of the Perceived Stress Scale and the Center for Epidemiologic Studies Depression Scale among Moroccan university students by Younes RAMI, Hicham KHABBACHE, Jamal AMRAOUI, Driss AIT ALI, Zakaria ABIDLI, Abdulmohsen MOHAMMED ABDULLAH ALKHULAYFI, Mahmood BAHRAMIZADEH, Hassan LAABOUB, Amelia RIZZO, Bouabid BADAOUI, Şeyhmus AKSOY, Lukasz SZARPAK, Murat YILDIRIM, Francesco CHIRICO

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Deep Learning-Based Identification of Echocardiographic Abnormalities From Electrocardiograms by Goro Fujiki, MD, Satoshi Kodera, MD, PhD, Naoto Setoguchi, MD, Kengo Tanabe, MD, PhD, Kotaro Miyaji, MD, PhD, Shunichi Kushida, MD, PhD, Mike Saji, MD, PhD, Mamoru Nanasato, MD, PhD, Hisataka Maki, MD, PhD, Hideo Fujita, MD, PhD, Nahoko Kato, MD, PhD, Hiroyuki Watanabe, MD, PhD, Minami Suzuki, MD, Masao Takahashi, MD, PhD, Naoko Sawada, MD, PhD, Jiro Ando, MD, Masataka Sato, MD, Shinnosuke Sawano, MD, PhD, Susumu Katsushika, MD, PhD, Hiroki Shinohara, MD, PhD, Norifumi Takeda, MD, PhD, Katsuhito Fujiu, MD, PhD, Hiroshi Akazawa, MD, PhD, Hiroyuki Morita, MD, PhD, Issei Komuro, MD, PhD

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Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms by Mie Suzuki Okutani, Shinya Okamura, Tang Gis, Hitomi Sasaki, Suni Lee, Akiho Kashiwabara, Simon Goto, Mai Matsumoto, Mayuko Yamawaki, Toshiaki Miyazaki, Tatsuya Nakagawa, Masahito Ikawa, Wataru Kamitani, Shiro Takekawa, Koichi Yamanishi, Hirotaka Ebina

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