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    Identification of Potential Diagnostic Biomarkers of Carotid Atherosclerosis in Obese Populations by Wu X, Pan J, Pan X, Kang J, Ren J, Huang Y, Gong L, Li Y

    Published 2025-02-01
    “…Xize Wu,1,* Jiaxiang Pan,2,* Xue Pan,1,3,* Jian Kang,1 Jiaqi Ren,1 Yuxi Huang,1 Lihong Gong,2,4 Yue Li2,4 1Graduate School, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, 110847, People’s Republic of China; 2Department of Cardiology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, 110032, People’s Republic of China; 3College of Traditional Chinese Medicine, Dazhou Vocational College of Chinese Medicine, Dazhou, Sichuan, 635000, People’s Republic of China; 4Liaoning Provincial Key Laboratory of TCM Geriatric Cardio-Cerebrovascular Diseases, Shenyang, Liaoning, 110032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lihong Gong; Yue Li, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33, Beiling Street, Huanggu District, Shenyang, Liaoning, 110032, People’s Republic of China, Tel +86 024-82961105, Email Linda1795@sina.com; med_liyue@163.comObjective: This study aimed to investigate the potential mechanisms and biomarkers between Obesity (OB) and carotid atherosclerosis (CAS).Methods: The GSE12828, GSE125771, GSE43292, and GSE100927 datasets were combined and normalized to obtain CAS-related differentially expressed genes (DEGs), and OB-related DEGs were obtained from the GSE151839 dataset and the GeneCards database. …”
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    Validation of Sleep Measurements of an Actigraphy Watch: Instrument Validation Study by Mari Waki, Ryohei Nakada, Kayo Waki, Yuki Ban, Ryo Suzuki, Toshimasa Yamauchi, Masaomi Nangaku, Kazuhiko Ohe

    Published 2025-01-01
    “…MethodsWe performed free-living sleep monitoring in 6 convenience-sampled participants without known sleep disorders recruited from within the Waki DTx Laboratory at the Graduate School of Medicine, University of Tokyo. To assess free-living sleep, we validated the iAide2 against a second actigraph that was previously validated against polysomnography, the MotionWatch 8 (MW8; CamNtech Ltd). …”
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    Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China by Shen D, Cai X, Hu J, Song S, Zhu Q, Ma H, Zhang Y, Ma R, Zhou P, Yang W, Hong J, Zhang D, Li N

    Published 2025-02-01
    “…Di Shen,1,* Xintian Cai,2,* Junli Hu,2 Shuaiwei Song,1 Qing Zhu,2 Huimin Ma,2 Yingying Zhang,2 Rui Ma,2 Pan Zhou,2 Wenbo Yang,2 Jing Hong,2 Delian Zhang,2 Nanfang Li2 1Graduate School, Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region, Hypertension Research Laboratory, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, Urumqi, Xinjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Nanfang Li, Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region “Hypertension Research Laboratory”, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, No. 91 Tianchi Road, Urumuqi, Xinjiang, 830001, People’s Republic of China, Tel +86 8564818, Email lnanfang2016@sina.comObjective: Hypertension development and progression are largely influenced by inflammation, which plays a critical role by activating the immune system and causing damage to the vascular endothelium. …”
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