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Intervention for Social Frailty Focusing on Physical Activity and Reducing Loneliness: A Randomized Controlled Trial
Published 2025-01-01“…Aki Gen, Yumi Higuchi, Tetsuya Ueda, Tomoko Hashimoto, Wataru Kozuki, Tatsunori Murakami, Mio Ishigami Graduate School of Rehabilitation Science, Osaka Metropolitan University, Habikino City, Osaka, JapanCorrespondence: Yumi Higuchi, Graduate School of Rehabilitation Science, Osaka Metropolitan University, 3-7-30 habikino, Habikino City, Osaka, 5830855, Japan, Tel +81 72 9502111, Fax +81 72 9502130, Email Higu_reha@omu.ac.jpPurpose: During the COVID-19 pandemic, older adults living in the community experienced reduced physical activity (PA) and heightened loneliness, particularly those with less frequent outings—a key factor of social frailty. …”
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Blockade of 4-1BB and 4-1BBL Interaction Reduces Obesity-Induced Skeletal Muscle Inflammation
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