How endocrine disruptors affect fish reproduction on multiple levels: A review by Socha Magdalena, Chyb Jarosław, Suder Aleksandra, Bojarski Bartosz

“…These compounds have negative impacts on gonads, oocyte maturation, steroidogenesis, and gametes. …”
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Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression. by Ankita Chavan, Lena Skrutl, Federico Uliana, Melanie Pfister, Franziska Brändle, Laszlo Tirian, Delora Baptista, Dominik Handler, David Burke, Anna Sintsova, Pedro Beltrao, Julius Brennecke, Madhav Jagannathan

“…Using genetics, transcriptomics, and small RNA profiling, we show that flies lacking D1 during embryogenesis exhibit transposon expression and gonadal atrophy as adults. We further demonstrate that this gonadal atrophy can be rescued by mutating the checkpoint kinase, Chk2, which mediates germ cell arrest in response to transposon mobilization. …”
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Critical appraisal of diagnostic laboratory tests in the evaluation of central precocious puberty by Kanthi Bangalore Krishna, Luigi Garibaldi

“…Pubertal onset is characterized by reactivation of the hypothalamic-pituitary-gonadal axis resulting in pulsatile gonadotropin secretion and subsequent sex steroid production. …”
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Giant Primary Retroperitoneal Teratoma in an Adult: A Case Report by Poonam Mathur, Miguel A. Lopez-Viego, Myron Howell

“…Teratomas are bizarre neoplasms derived from embryonic tissues that are typically found only in the gonadal and sacrococcygeal regions of adults. Retroperitoneal teratomas are rare and present challenging management options. …”
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Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells by Francesco Orio, Giovanna Muscogiuri, Stefano Palomba, Bianca Serio, Mariarosaria Sessa, Valentina Giudice, Idalucia Ferrara, Libuse Tauchmanovà, Annamaria Colao, Carmine Selleri

“…Moreover, overt or subclinical thyroid complications (including persistent low-T3 syndrome, chronic thyroiditis, subclinical hypo- or hyperthyroidism, and thyroid carcinoma), gonadal failure, and adrenal insufficiency may persist many years after HSCT. …”
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Understanding Genetic Regulation of Sex Differentiation in Hermaphroditic Fish by Junchao Fang, Guanglve Li, Wenyin Luo, Qiaomu Hu

“…The present review delves into the histological dynamics during gonadal development across three types of sequential hermaphroditic fish, meticulously delineating the pivotal characteristics at each stage, from the inception of primordial gonads to sexual specialization. …”
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Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes by Miguel Vasconcelos Almeida, Moritz Blumer, Chengwei Ulrika Yuan, Pío Sierra, Jonathan L. Price, Fu Xiang Quah, Aleksandr Friman, Alexandra Dallaire, Grégoire Vernaz, Audrey L. K. Putman, Alan M. Smith, Domino A. Joyce, Falk Butter, Astrid D. Haase, Richard Durbin, M. Emília Santos, Eric A. Miska

“…The expanded piwil1 copies have signatures of positive selection and retain amino acid residues essential for catalytic activity. Furthermore, the gonads of African cichlids express a Piwi-interacting RNA (piRNA) pathway that targets TEs. …”
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UN CASO DE DESORDEN DEL DESARROLLO SEXUAL EN UN CANINO MESTIZO by S. Valencia, J. C. González, J. C. Rincón

“…Se clasifican en tres grupos de anormalidades: del desarrollo cromosómico, del desarrollo gonadal y del sexo fenotípico, y presentan diferentes subcate - gorías. …”
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ADAM19: A Novel Target for Metabolic Syndrome in Humans and Mice by Lakshini Weerasekera, Caroline Rudnicka, Qing-Xiang Sang, Joanne E. Curran, Matthew P. Johnson, Eric K. Moses, Harald H. H. Göring, John Blangero, Jana Hricova, Markus Schlaich, Vance B. Matthews

“…Secondly, we examined the expression of ADAM19 in liver and gonadal white adipose tissue using an in vivo diet induced obesity mouse model. …”
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Giant Mature Primary Retroperitoneal Teratoma in a Young Adult: Report of a Rare Case and Literature Review by Walid Sasi, Giuseppe A. Ricchetti, Laila Parvanta, Robert Carpenter

“…Teratomas are neoplasms of the embryonic tissues that typically arise in the gonadal and sacrococcygeal regions of adults and children. …”
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Reference genome provide insights into sex determination of silver aworana (Osteoglossum bicirrhosum) by Yi Liu, Chao Bian, Ka Yan Ma, Yexin Yang, Yuanyuan Wang, Chao Liu, Guochang Ouyang, Meng Xu, Jinhui Sun, Changwei Shao, Jiehu Chen, Qiong Shi, Xidong Mu

“…Transcriptome sequencing of gonads support our hypothesis that the regulation of foxl2 can be influenced by the spatial proximity of the female-specific fragment, thereby promoting ovarian function or inhibiting testicular function to stimulate gonadal differentiation. …”
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Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction by Erika Cottone, Valentina Pomatto, Patrizia Bovolin

“…The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. …”
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A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male by Sammy G. Nakhla, Srinath Sundararajan

“…Mediastinal germ cell tumors have a worse prognosis than gonadal germ cell tumors. Chemotherapy followed by adjuvant surgery improves overall response in EGGCTs. …”
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A Rare Case of Metastatic Choriocarcinoma of Lung Origin by Parth Rali, Jianwu Xie, Grishma Rali, Mayur Rali, Jan Silverman, Khalid Malik

“…To diagnose primary pulmonary choriocarcinoma, the patient should have no previous gynecologic malignancy, have elevated human chorionic gonadotropin, and have pathological confirmation of the disease excluding gonadal primary site of the tumor. Due to the paucity of data, there are no guidelines for treatment. …”
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Testosterone-Induced Effects on Lipids and Inflammation by Stella Vodo, Nicoletta Bechi, Anna Petroni, Carolina Muscoli, Anna Maria Aloisi

“…In the study of pain, great attention has been paid to the possible involvement of gonadal hormones, especially in recent years. In particular, testosterone, the main androgen, is thought to play a beneficial, protective role in the body. …”
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Adiponectin: A New Regulator of Female Reproductive System by Kamil Dobrzyn, Nina Smolinska, Marta Kiezun, Karol Szeszko, Edyta Rytelewska, Katarzyna Kisielewska, Marlena Gudelska, Tadeusz Kaminski

“…The presence of adiponectin and its receptors in the structures responsible for the regulation of female reproductive functions, such as hypothalamic-pituitary-gonadal (HPG) axis, indicates that adiponectin may be involved in the female fertility regulation. …”
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Endocrine and metabolic alterations in response to systemic inflammation and sepsis: a review article by Syed Faizan Mehdi, Muhammad Hamza Qureshi, Salman Pervaiz, Karishma Kumari, Edwin Saji, Mahnoor Shah, Ahmad Abdullah, Kamran Zahoor, Hafiza Amna Qadeer, Disha Kumari Katari, Christine Metz, Lopa Mishra, Derek LeRoith, Kevin Tracey, Michael J. Brownstein, Jesse Roth

“…Increased cortisol or cortisolemia is evident throughout the acute phase, along with changes in the hypothalamic pituitary thyroid (HPT) axis, growth hormone-IGF-1 axis, insulin-glucose axis, leptin, catecholamines, renin angiotensin aldosterone axis, ghrelin, glucagon, hypothalamic pituitary gonadal (HGA) axis, and fibroblast growth factor-21. …”
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Septo-Optic Dysplasia Diagnosed in a Newborn Infant with Normoglycemia: The Importance of Thorough Physical Examination by Aishwarya Palorath, Ishita Kharode

“…Ultrasound imaging confirmed the presence of both gonads in the inguinal canal, with no Müllerian structures visualized. …”
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Role of Imaging in the Diagnosis and Management of Complete Androgen Insensitivity Syndrome in Adults by Marco Nezzo, Pieter De Visschere, Guy T'Sjoen, Steven Weyers, Geert Villeirs

“…Imaging can be important both to diagnose the pathology and to localize gonads prior to surgical treatment. In this paper, we present three cases of complete androgen insensitivity syndrome in adult women of 34, 22, and 38 years old.…”
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Sex and gender differences in pain perception and management in clinical settings by Jakara Morgan, Krystal Magwood, Joslyn Smith, Marjorie R. Jenkins, Alyson J. McGregor, Kelly M. Quesnelle

“…Pain perception can differ amongst the sexes based on a myriad of reasons such as differences in gonadal hormones or chronic pain syndromes. The purpose of this narrative literature review is to report physiologic and pharmacokinetic differences between the sexes and highlight the possible biases in pain treatment amongst men and women. …”
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