Stem Cell Interaction with Somatic Niche May Hold the Key to Fertility Restoration in Cancer Patients by Deepa Bhartiya, Kalpana Sriraman, Seema Parte

“…Postnatal oogenesis in mammalian ovary from VSELs may be exploited for fertility restoration in cancer survivors including those who were earlier deprived of gametes and/or gonadal tissue cryopreservation options.…”
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Resistin Regulates Pituitary Lipid Metabolism and Inflammation In Vivo and In Vitro by F. Rodriguez-Pacheco, M. G. Novelle, M. J. Vazquez, E. Garcia-Escobar, F. Soriguer, G. Rojo-Martinez, E. García-Fuentes, M. M. Malagon, C. Dieguez

“…The adipokine resistin is an insulin-antagonizing factor that also plays a regulatory role in inflammation, immunity, food intake, and gonadal function and also regulates growth hormone (GH) secretion in rat adenopituitary cells cultures with the adipokine. …”
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Megestrol Acetate-Induced Symptomatic Hypogonadism in a Male Patient by Lubna Bashir Munshi, Yumiko Tsushima, Kwan Cheng, Maria Brito

“…The hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pituitary-gonadal (HPG) axis are very sensitive and can be affected by external factors like stress, starvation, and medication. …”
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Beta-Thalassemia Major and Female Fertility: The Role of Iron and Iron-Induced Oxidative Stress by Paraskevi Roussou, Nikolaos J. Tsagarakis, Dimitrios Kountouras, Sarantis Livadas, Evanthia Diamanti-Kandarakis

“…Infertility in these women seems to be attributed to iron deposition and iron-induced oxidative stress (OS) in various endocrine organs, such as hypothalamus, pituitary, and female reproductive system, but also through the iron effect on other organs, such as liver and pancreas, contributing to the impaired metabolism of hormones and serum antioxidants. Nevertheless, the gonadal function of these patients is usually intact and fertility is usually retrievable. …”
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Systemic and Nonrenal Adverse Effects Occurring in Renal Transplant Patients Treated with mTOR Inhibitors by Gianluigi Zaza, Paola Tomei, Paolo Ria, Simona Granata, Luigino Boschiero, Antonio Lupo

“…In particular, mTOR-I may induce systemic nonnephrological side effects including pulmonary toxicity, hematological disorders, dysmetabolism, lymphedema, stomatitis, cutaneous adverse effects, and fertility/gonadic toxicity. Although most of the adverse effects are dose related, it is extremely important for clinicians to early recognize them in order to reduce dosage or discontinue mTOR-I treatment avoiding the onset and development of severe clinical complications.…”
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Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl by Laura Kasongo, Patricia Forget, Ramona Corina Nicolescu

“…Precocious puberty, as paraneoplastic endocrine syndrome, has already been described in children with malignant tumors (brain, gonadal, adrenal tumors, and hepatoblastoma). However, little is known about central precocious puberty, as paraneoplastic manifestation of nephroblastoma or secondary to its specific chemotherapy. …”
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Reproductive Cycle of Marphysa sanguinea (Montagu, 1815) (Polychaeta: Eunicidae) in the Lagoon of Tunis by Monia El Barhoumi, Patrick Scaps, Fathia Zghal

“…There were no morphological differences between males and females, and spawning occurred without epitokal metamorphosis. Gonads are not well defined in either sex. The process of spermatogenesis takes place in the coelomic cavity. …”
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Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava by Marie Dusaud, Younes Bayoud, François-Régis Desfemmes, Benoît Molimard, Xavier Durand

“…The thrombus extended from the left gonadal vein to the left renal vein to the IVC. The fluorine-18 fluorodeoxyglucose (f-FDG) positron emission tomography (PET) computerized tomography (CT) demonstrated a hypermetabolic focus in the retroperitoneum and in the IVC thrombus. …”
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Chemotherapy as a Remedy to Gynaecological Cancers: Challenges and Coping Patterns Among Young Women by Titilayo Omolekan, Gbemisola Bolanle Ogbeye, Risikat Idowu Fadare

“…Young women are at a heightened risk of infertility due to the gonadal toxic therapy-induced decrease of ovarian function. …”
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Traumatic Brain Injury and Hypopituitarism by Gianluca Aimaretti, Ezio Ghigo

“…It has been suggested that patients with TBI-induced hypopituitarism may benefit with appropriate hormonal replacement receiving replacement therapy such as anti-diuretic hormone (ADH), glucocorticoid and thyroid hormones when needed. Gonadal and recombinant human Growth Hormone (rhGH) replacement therapy should also be introduced if there are deficiencies demonstrated and even reconfirmed in a second step. …”
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Association between Sex Hormone and Blood Uric Acid in Male Patients with Type 2 Diabetes by Wen Cao, Ren-Dong Zheng, Shu-Hang Xu, Yao-Fu Fan, Hong-Ping Sun, Chao Liu

“…SUA and body mass index were found to be risk factors for gonadal dysfunction. Therefore, we conclude that hypogonadism of male patients with T2DM is related to SUA level.…”
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GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147 by Yu You, Konglin Huo, Liang He, Tongyue Wang, Lei Zhao, Rong Li, Xiaoqing Cheng, Xuebin Ma, Zhiying Yue, Stefan Siwko, Ning Wang, Lujian Liao, Mingyao Liu, Jian Luo

“…Abstract Reproductive hormones associated with the hypothalamic-pituitary-gonadal (HPG) axis are closely linked to bone homeostasis. …”
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Chemokine (C-X-C) Ligand 12 Facilitates Trafficking of Donor Spermatogonial Stem Cells by Zhiyv Niu, Shaun M. Goodyear, Mary R. Avarbock, Ralph L. Brinster

“…The chemokine (C-X-C) receptor type 4 (CXCR4) is an early marker of primordial germ cells (PGCs) essential for their migration and colonization of the gonads. In spermatogonial stem cells (SSCs), the expression of CXCR4 is promoted by the self-renewal factor, glial cell line-derived neurotrophic factor (GDNF). …”
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Inhibins Tune the Thymocyte Selection Process by Regulating Thymic Stromal Cell Differentiation by Ebzadrel Carbajal-Franco, Marisol de la Fuente-Granada, Germán R. Alemán-Muench, Eduardo A. García-Zepeda, Gloria Soldevila

“…These ligands were initially identified as hormones that regulate the hypothalamus-pituitary-gonadal axis; however, increasing evidence has demonstrated that they are key regulators in the immune system. …”
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Hormonal Modulation in Aging Patients with Erectile Dysfunction and Metabolic Syndrome by Inês Campos Costa, Hugo Nogueira Carvalho, Luís Pacheco-Figueiredo, Inês Tomada, Nuno Tomada

“…Regarding the hypothalamic-pituitary-gonadal axis, patients with hypogonadism did not exhibit raised LH levels. …”
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High Doses of Caffeine during the Peripubertal Period in the Rat Impair the Growth and Function of the Testis by Minji Park, Yuri Choi, Hyeonhae Choi, Ju-Yearn Yim, Jaesook Roh

“…Thus, it is conceivable that peripubertal caffeine exposure would also influence physiologic gonadal changes and function during this critical period for sexual maturation. …”
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The Role of the Multiple Hormonal Dysregulation in the Onset of “Anemia of Aging”: Focus on Testosterone, IGF-1, and Thyroid Hormones by Marcello Maggio, Francesca De Vita, Alberto Fisichella, Fulvio Lauretani, Andrea Ticinesi, Graziano Ceresini, Anne Cappola, Luigi Ferrucci, Gian Paolo Ceda

“…Ageing process is also characterized by a “multiple hormonal dysregulation” with disruption in gonadal, adrenal, and somatotropic axes. Experimental studies suggest that anabolic hormones such as testosterone, IGF-1, and thyroid hormones are able to increase erythroid mass, erythropoietin synthesis, and iron bioavailability, underlining a potential role of multiple hormonal changes in the anemia of aging. …”
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Induction of tyrosine aminotransferase in mice is inhibited by activated metabolites of ortho- aminoazotoluene by V. I. Kaledin, S. I. Ilnitskaya, N. A. Popova, O. A. Koval, I. A. Pyshnaya, L. F. Gulyaeva

“…Mouse strains differing in the sensitivity to both carcinogenic and antiglucocorticoid (TAT induction inhibitory) effects of the mouse-specific carcinogen ortho- aminoazotoluene (OAT) underwent a set of experimental procedures: ablation of gonadal and adrenal glands, administration of inhibitors (CoCl2, pentachlorophenol), inducers (3,4- benzopyrene, Aroclor 1254, 20-methylcholanthrene) of xenobiotic-metabolizing enzyme activities, and others. …”
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Germline-restricted chromosomes of the songbirds by P. M. Borodin

“…Some GRC genes are actively expressed in female and male gonads, controlling the development of germline cells and synthesis of the proteins involved in the organization of meiotic chromosomes. …”
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Coral fisheries management using an ecosystem approach in the domain of fishing techniques at the Pasiran fish landing base by Muammar Mesha Abel, Rahmah Alvi, Agustina Imelda, Sriwulanda Ayu

“…However, its management faces several challenges, including seasonal dependency of fishermen, fishing practices targeting fish below their gonadal maturity level, repeated exploitation of the same fishing grounds, and the use of traditional poisons. …”
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