From Pioneering Discoveries to Innovative Therapies: A Journey Through the History and Advancements of Nanoparticles in Breast Cancer Treatment by Basingab FS, Alshahrani OA, Alansari IH, Almarghalani NA, Alshelali NH, Alsaiary AH, Alharbi N, Zaher KA

“…The advent of nanotechnology has introduced a new era characterized by the development of various nanoparticles, including liposomes, dendrimers, and gold nanoparticles, designed to target cancer cells with remarkable precision. …”
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Leptospirosis Risk Assessment in Rodent Populations and Environmental Reservoirs in Humanitarian Aid Settings in Thailand by Panadda Krairojananan, Kasima Wasuworawong, Surachai Leepitakrat, Taweesak Monkanna, Elizabeth W. Wanja, Silas A. Davidson, Betty K. Poole-Smith, Patrick W. McCardle, Alyssa Mann, Erica J. Lindroth

“…Military personnel deployed in endemic areas, such as during the Cobra Gold Joint exercise, face heightened exposure. This study assessed <i>Leptospira</i>’s prevalence in rodents and environmental reservoirs at military training sites from 2017 to 2022. …”
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<i>Clostridium difficile</i>-associated disease by V. T. Ivashkin, O. S. Shifrin, A. S. Tertycnhy, Ye. A. Poluektova, T. L. Lapina, O. S. Lyashenko, K. V. Ivashkin

“…However, which of these methods may be considered to be «the gold standard» is unclear yet. Metronidazole, vancomycin, dioctaedric smectite and probiotics are used for treatment of C. difficile infection. …”
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A child with Chronic Nonbacterial Osteomyelitis and celiac disease: accidental association or two different aspects of the same condition? by Grazia Bossi, Maria Sole Prevedoni Gorone, Luca Lungarotti, Francesco Pelillo, Amelia Mascolo, Matteo Naso, Daniele Veraldi, Francesca Olivero, Costanza Chirico, Maria Vittoria Marino, Cristina Dutto, Gian Luigi Marseglia

“…Whole Body Magnetic Resonance (WBMR) and bone biopsy are the gold standard for the diagnosis. Although the association with Inflammatory Bowel Disease (IBD) has been reported in the literature, cases of CNO in celiac patients have never been described before. …”
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A Real-World Comparison Between Adjuvant Docetaxel with Cyclophosphamide (TC) and Anthracycline–Taxane Chemotherapy in Early HER-2 Negative Breast Cancer by Danilo Giffoni de Mello Morais Mata, Rossanna C. Pezo, Kelvin K. W. Chan, Ines Menjak, Andrea Eisen, Maureen Trudeau

“…Background: Anthracycline–taxane chemotherapy is the gold standard in high-risk breast cancer (BC), despite the potential risk of congestive heart failure (CHF). …”
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Highlights of Thirty-Year Experience of CO2 Laser Use at the Florence (Italy) Department of Dermatology by Piero Campolmi, Paolo Bonan, Giovanni Cannarozzo, Andrea Bassi, Nicola Bruscino, Meena Arunachalam, Michela Troiano, Torello Lotti, Silvia Moretti

“…The CO2 laser has been used extensively in dermatological surgery over the past 30 years and is now recognised as the gold standard for soft tissue vaporization. Considering that the continuous wave CO2 laser delivery system and the newer “superpulsed” and scanned CO2 systems have progressively changed our practice and patient satisfaction, a long range documentation can be useful. …”
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Renal transplant recipient and deceased-donor risk profiles at Wits Donald Gordon Medical Centre, Johannesburg, South Africa: A 9-year review by F van der Schyff, M Barnard, B Ströbele, M de Jager, R Britz, P Gaylard, J Loveland

“…Renal transplantation is the gold-standard therapy for end-stage renal disease. …”
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Optimizing Microneutralization and IFN-γ ELISPOT Assays to Evaluate Mpox Immunity by Yinyi Yu, Krystal Meza, Chase Colbert, Daniel F. Hoft, Anna Jaunarajs, Azra Blazevic, Sharon E. Frey, Getahun Abate

“…Optimization and further development of FRNT were conducted using the plaque reduction neutralization test (PRNT) as the gold standard. The mpox-specific IFN-γ ELISPOT assay was optimized using different mpox antigen preparations. …”
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Enterocytozoon bieneusi Identification Using Real-Time Polymerase Chain Reaction and Restriction Fragment Length Polymorphism in HIV-Infected Humans from Kinsh... by Roger Wumba, Menotti Jean, Longo-Mbenza Benjamin, Mandina Madone, Kintoki Fabien, Zanga Josué, Sala Jean, Kendjo Eric, Guillo-Olczyk AC, Thellier Marc

“…The diagnosis performance of the indirect immune-fluorescence-monoclonal antibody (IFI-AcM) was defined in comparison with real-time PCR as the gold standard. Results. Out of 242 HIV-infected patients, using the real-time PCR, the prevalence of E. bieneusi was 7.9% (n=19) among the 19 E. bieneusi, one was coinfected with E. intestinalis. …”
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Dual-modal radiomics ultrasound model to diagnose cervical lymph node metastases of differentiated thyroid carcinoma: a two-center study by Jiajia Tang, Yan Tian, Jiaojiao Ma, Xuehua Xi, Liangkai Wang, Zhe Sun, Xinyi Liu, Xuejiao Yu, Bo Zhang

“…Pathological results were set as gold standard. We extracted radiomic characteristics from grayscale ultrasound and CDFI images, then applied lasso (least absolute shrinkage and selection operator) regression analysis to analyze radiomics features and calculate the rad-score. …”
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Cu66 nanoclusters from hierarchical square motifs: Synthesis, assembly, and catalysis by Xueli Sun, Yuchen Wang, Qingyuan Wu, Ying‐Zi Han, Xuekun Gong, Xiongkai Tang, Christine M. Aikens, Hui Shen, Nanfeng Zheng

“…While recent studies have provided valuable insights into the multiscale assembly patterns of gold or silver‐based nanoclusters, the success in achieving similar results for copper analogues has been notably limited. …”
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Clinical Burden and Healthcare Resource Use of Asthma in Children in the UK by Gouia I, Joulain F, Zhang Y, Morgan CL, Khan AH

“…We assessed the clinical and economic burden of asthma in children in the UK to better understand the impact of pediatric asthma.Methods: This was a retrospective, case-matched, longitudinal analysis using the Clinical Practice Research Datalink GOLD database and linked patient-level data (Hospital Episode Statistics and Office for National Statistics datasets) of selected patient (aged 6– 11 years) records in 2017. …”
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Assessing recovery time of ecosystems in China: insights into flash drought impacts on gross primary productivity by M. Lu, M. Lu, H. Sun, H. Sun, H. Sun, Y. Yang, J. Xue, H. Ling, H. Zhang, W. Zhang

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Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer by Angelica Nogueira Rodrigues, Andreza Karine de Barros Almeida Souto, Diocésio Alves Pinto de Andrade, Larissa Müller Gomes, Sandra Satie Koide, Renata de Godoy e Silva, Bruno Batista de Souza, Juliana Doblas Massaro, Andréia Cristina de Melo, Andrea Morais Borges, Camila Giro, Carlos Augusto Vasconcelos de Andrade, Cesar Martins da Costa, Daniel Luiz Gimenes, Eduardo Caminha Bandeira de Mello, Fernanda Cesar de Oliveira, Frederico Müller de Toledo Lima, Gabriel Lima Lopes, Gustavo de Oliveira Bretas, Gustavo Guerra Jacob, Herika Lucia da Costa Silva, Juliana Ferrari Notaro, Lara Ladislau Alves, Marcos Veloso Moitinho, Mirian Cristina da Silva, Roberto Abramoff, Thais Amaral da Cunha Rauber, Rodrigo Dienstmann, Fernanda Christtanini Koyama

“…We assessed the performance of the in-house test (GS Focus HRD) using Cohen’s kappa statistic to measure agreement with the gold standard assay (MyChoice® HRD Plus CDx) in HRD status classification, along with other accuracy metrics.ResultsIn total, 41 samples were analyzed (20 HRD-positive, 19 HRD-negative, and 2 inconclusive results with the MyChoice® HRD Plus CDx assay). …”
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Subcutaneous Fat Obesity in a High Body Mass Index Donor Is Not a Contraindication to Living Donor Hepatectomy by Hirak Pahari, Amey Sonavane, Amruth Raj, Anup Kumar Agrawal, Ambreen Sawant, Deepak Kumar Gupta, Amit Gharat, Vikram Raut

“…Intraoperative visualization in these donors remains the gold standard to decide the need for biopsy. Living donor hepatectomy may be safely performed in a select group of high BMI patients (>35 kg/m2) with pure subcutaneous fat obesity in the absence of other suitable living donors.…”
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The diagnostic value of cytology in the mammary intraductal lesions of patients with pathological nipple discharge by Yifei Zeng, Jifeng Li, Dongxiao Zhang, Na Fu, Yu Zhou, Yubo Guo, Min Liu, Hongkai Zhang, Jianchun Cui

“…With postoperative pathological diagnosis as the gold standard, we compared the clinical diagnostic efficacy of the two cytology techniques applied independently and combined with FDS to evaluate their diagnostic value in intraductal lesions. …”
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Comparison of Illumina and Oxford Nanopore sequencing data quality for Clostridioides difficile genome analysis and their application for epidemiological surveillance by Semeh Bejaoui, Sofie Holtsmark Nielsen, Astrid Rasmussen, John Eugenio Coia, Dorte Terp Andersen, Tobias Bruun Pedersen, Martin Vad Møller, Marc Trunjer Kusk Nielsen, Dorte Frees, Søren Persson

“…While Illumina short-read sequencing has been adopted as the gold standard to investigate C. difficile virulence and transmission routes, little is known about the potential of Nanopore long-read sequencing in this field. …”
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Evaluation of a PCR-based lateral flow device for detecting Aspergillus and Candida species from clinical specimens by Ariff Khalid, Jacinta Santhanam, Mohd Nizam Tzar, Ang-Lim Chua, Sharifah Fadilah Abdul Wahid, Wan Rahiza Wan Mat, Raha Abd Rahman, Petrick Periyasamy

“…The LFA dipstick, in a modified sandwich format, utilises immobilised antibodies complementary to the fluorophore labels on the PCR products, and gold nanoparticles to form a visible red line that indicates the presence of the targeted fungus. …”
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Risk factors for renal insufficiency and survival implications after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: a systematic review by Zhigao Huang, Zhuo Liu, Lin Zhuo, Xin Ma, Zhenbin Jiang, Kewei Chen, Jiyuan Chen, Yuxuan Li, Guoliang Wang, Xiaojun Tian, Hongxian Zhang, Lei Liu, Lulin Ma, Kai Hong, Shudong Zhang

“…Radical nephrectomy (RN) with thrombectomy seems to be its gold standard operation, which might cause reduction of renal function. …”
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Elastosonographic Evaluation of Endometrium in Postmenopausal Bleeding by İsmail Burak Gültekin, Orhan Altınboğa, Serap Gültekin, Elif Akkaş Yılmaz, Gökşen İnanç İmamoğlu, Afra Alkan, Tuncay Küçüközkan

“…CONCLUSION: Tissue biopsy for histopathologic evaluation is still the gold standart in cases with postmenopausal bleeding. …”
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