Impact of the COVID-19 pandemic on type 2 diabetes care and factors associated with care disruption in Kenya and Tanzania by Richard E. Sanya, Caroline H. Karugu, Peter Binyaruka, Shukri F. Mohamed, Lyagamula Kisia, Peter Kibe, Irene Mashasi, Grace Mhalu, Christopher Bunn, Manuela Deidda, Frances S. Mair, Eleanor Grieve, Cindy M. Gray, Sally Mtenga, Gershim Asiki

“…A questionnaire captured data on blood glucose testing, changes in medication prescription and access, and healthcare provider access. …”
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Fish Scale-Derived Scaffolds for Culturing Human Corneal Endothelial Cells by Mohit Parekh, Bert Van den Bogerd, Nadia Zakaria, Diego Ponzin, Stefano Ferrari

“…Cell morphology, proliferation/migration, and glucose uptake were studied (n=30). Hoechst, ethidium homodimer, and calcein AM (HEC) staining was performed to determine viability and toxicity (n=6). …”
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Predictive biomarkers for cardiometabolic risk in postmenopausal women: insights into visfatin, adropin, and adiponectin by Anna Maria Cybulska, Daria Schneider-Matyka, Ireneusz Walaszek, Mariusz Panczyk, Dorota Ćwiek, Anna Lubkowska, Elżbieta Grochans, Kamila Rachubińska, Katarzyna Malewicz, Mariusz Chabowski, Mariusz Chabowski

“…Circulating adropin negatively correlated with HbA1C, fasting blood glucose, and insulin. Adiponectin negatively correlated with HbA1C, fasting blood glucose, insulin, and triglycerides. …”
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Olivetol’s Effects on Metabolic State and Gut Microbiota Functionality in Mouse Models of Alimentary Obesity, Diabetes Mellitus Type 1 and 2, and Hypercholesterolemia by Anastasia A. Zabolotneva, Katerina E. Popruga, Valentin V. Makarov, Sergei M. Yudin, Andrei M. Gaponov, Sergei A. Roumiantsev, Aleksandr V. Shestopalov

“…Background: Disorders of glucose and lipid metabolism, such as obesity, diabetes mellitus, or hypercholesterolemia, can cause serious complications, reduce quality of life, and lead to increased premature mortality. …”
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Multiple low-dose radiation ameliorates type-2 diabetes mellitus via gut microbiota modulation to activate TLR4/MyD88/NF-κB pathway by Lijing Qin, Rongrong Liu, Zhen Jia, Weiqiang Xu, Li Wang, Hongyuan Tian, Xinru Lian, Wen Li, Yali Qi, Huan He, Zhicheng Wang

“…The changes of blood glucose levels, body weight, and the damage of pancreas were measured. …”
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Effects of dietary bile acid on the growth performance, intestinal health, blood biochemistry, and antioxidative response of Nile tilapia (Oreochromus niloticus) fed high-fat diets by Mahmoud A.O. Dawood, Sameh El-Dahan, Samy Elsaadawy, Ahmed E. Noreldin, Hani Sewilam

“…Fish-fed HF diet also showed increased total cholesterol, triglycerides, glucose, ALP, and AST levels as well as the malondialdehyde level (MDA). …”
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Ex Vivo Expansion of Murine MSC Impairs Transcription Factor-Induced Differentiation into Pancreatic β-Cells by Dario Gerace, Rosetta Martiniello-Wilks, Rosaline Habib, Binhai Ren, Najah Therese Nassif, Bronwyn Anne O’Brien, Ann Margaret Simpson

“…Transduced MSCs did not undergo pancreatic transdifferentiation, as determined by RT-PCR analyses, lacked glucose responsiveness, and upon transplantation did not reverse diabetes. …”
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Serum apolipoproiein b-100 concentrations in periparturienl diseases of dairy cows by Turan Civelek, Mutlu Sevinç

“…Serum concent rations of glucose, cholesterol, triglyceride, tola! pıoteın. albumin, AST, GGT and HDL were measured enzimatically. …”
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Combined Administration of Streptozotocin and Sucrose Accelerates the Appearance of Type 2 Diabetes Symptoms in Rats by Martha Isela Barragán-Bonilla, Juan Miguel Mendoza-Bello, Penélope Aguilera, Isela Parra-Rojas, Berenice Illades-Aguiar, Mónica Ramírez, Mónica Espinoza-Rojo

“…With the rats at 14 weeks of age, we determined the following: (a) fasting blood glucose, (b) oral glucose tolerance, and (c) insulin tolerance. …”
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Relationship between physical activity during pregnancy and maternal health outcomes: evidence from the MAASTHI cohort study in Bengaluru, India by Yamuna Ana, Floor A. van den Brand, Onno C. P. van Schayck, Giridhara R. Babu

“…We assessed presence of depressive symptoms and conducted oral glucose tolerance tests, hemoglobin and blood pressure assessments, anthropometric measurements, and collected delivery details. …”
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Strategic bioprocessing of A. protothecoides and C. sorokiniana using renewable feedstocks for targeted bioproduct and biodiesel generation by Eleni Krikigianni, Kyriakos Antoniadis, Paul Christakopoulos, Ulrika Rova, Leonidas Matsakas, Alok Patel

“…Heterotrophic cultivation of A. protothecoides (AP) and C. sorokiniana (CS) in glucose showed enhanced cell growth with organic N-sources. …”
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Preterm Birth and Cardiometabolic Health Trajectories From Birth to Adulthood: The Avon Longitudinal Study of Parents and Children by Gemma L. Clayton, Laura D. Howe, Linda M. O'Keeffe, Adam J. Lewandowski, Deborah A. Lawlor, Abigail Fraser

“…There was no evidence of differences in glucose and insulin. Conclusions Few, modest differences in cardiometabolic health were found in those born preterm versus term. …”
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Effects of Sitagliptin Treatment on Dysmetabolism, Inflammation, and Oxidative Stress in an Animal Model of Type 2 Diabetes (ZDF Rat) by Liliana Ferreira, Edite Teixeira-de-Lemos, Filipa Pinto, Belmiro Parada, Cristina Mega, Helena Vala, Rui Pinto, Patrícia Garrido, José Sereno, Rosa Fernandes, Paulo Santos, Isabel Velada, Andreia Melo, Sara Nunes, Frederico Teixeira, Flávio Reis

“…Sitagliptin in diabetic rats promoted a decrease in glucose, HbA1c, Total-c, and TGs accompanied by a partial prevention of insulinopenia, together, with a decrease in CRPhs and IL-1β. …”
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Comparison of different severe obesity definitions in predicting future cardiometabolic risk in a longitudinal cohort of children by Gilles Paradis, Melanie Henderson, Lisa Kakinami, Angelo Tremblay, Anna Smyrnova

“…Whether SO definitions differentially predict cardiometabolic disease risk is critical for proper clinical care and management but is unknown.Design Prospective cohort studySetting SO definitions were applied at baseline (2005–2008, Mage=9.6 years, n=548), and outcomes (fasting lipids, glucose, homoeostatic model assessment (HOMA-IR) and blood pressure) were assessed at first follow-up (F1: 2008–2011, Mage=11.6 years) and second follow-up (2015–2017, Mage=16.8 years) of the Quebec Adipose and Lifestyle Investigation in Youth cohort in Montreal, Quebec.Participants Respondents were youth who had at least one biological parent with obesity.Primary outcome measures Unfavourable cardiometabolic levels of fasting blood glucose (≥6.1 mmol/L), insulin resistance (HOMA-IR index ≥2.0), high-density lipoprotein <1.03 mmol/L, low-density lipoprotein ≥2.6 mmol/L and triglycerides >1.24 mmol/L. …”
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NLRP3 inflammasome activation and disruption of IRS-1/PI3K/AKT signaling: Potential mechanisms of arsenic-induced pancreatic beta cells dysfunction in rats by Yonglian Liu, Wenjuan Wang, Bing Liang, Zhonglan Zou, Aihua Zhang

“…In vitro, NaAsO2-treated INS-1 cells exhibited a dose-dependent reduction in glucose-stimulated insulin secretion. Furthermore, arsenic exposure in these cells activated the NLRP3 inflammasome, suppressed the IRS-1/PI3K/AKT signaling pathway, and downregulated insulin secretion regulatory molecules (PDX-1, GLUT2, and GCK). …”
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Upregulation of Tumor Necrosis Factor-α-Induced Protein 8-Like 2 mRNA Is Negatively Correlated with Serum Concentrations of Tumor Necrosis Factor-α and Interleukin 6 in Type 2 Diab... by Yongliang Liu, Xinmei Wang, Yan Zhao, Peiqing Zhao, Lianqing Wang, Qiaoli Zhai, Xiaowei Zhang, Wenxiu Tian, Xinxin Xiang, Tao Li

“…TIPE2 was significantly increased in PBMCs from T2DM patients compared with those from healthy controls and was negatively correlated with serum TNF-α, IL-6, and hsCRP concentrations but positively correlated with HbA1c and LDL-C in T2DM patients. High glucose treatment (50 mmol/L) can upregulate the expression of TIPE2 and cytokine secretion in differentiated THP-1 cells. siTIPE2 infection exacerbated the increased TNF-α and IL-6 concentrations in differentiated THP-1 cells under high glucose conditions (50 mmol/L), while infection with TIPE2 adenovirus reversed the increased TNF-α concentration. …”
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Serum Fibroblast Growth Factor 21 Levels Are Positively Associated with Metabolic Syndrome in Patients with Type 2 Diabetes by Ruo-Yao Gao, Bang-Gee Hsu, Du-An Wu, Jia-Sian Hou, Ming-Chun Chen

“…Univariate linear analysis revealed that hypertension, BMI, WC, body fat mass, SBP, DBP, logarithmically transformed TG (log-TG), low-density lipoprotein cholesterol (LDL-C) level, log-glucose, log-creatinine, log-UACR, log-insulin, and log-HOMA-IR positively correlated, whereas HDL-C and eGFR negatively correlated with serum FGF21 levels in T2DM patients. …”
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What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review by Benedict Hayhoe, Azeem Majeed, Geva Greenfield, Ana Luísa Neves, Henock B Taddese, Kalthum Patail, Hui Hsuan Pai

“…While self-management behaviours like healthy eating and monitoring of blood glucose help to reduce the care burden, they are still perceived to be burdensome. …”
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PPAR-α Agonist Fenofibrate Decreased Serum Irisin Levels in Type 2 Diabetes Patients with Hypertriglyceridemia by Xiaomeng Feng, Xia Gao, Yumei Jia, Heng Zhang, Qingrong Pan, Zhi Yao, Ning Yang, Jia Liu, Yuan Xu, Guang Wang, Xinchun Yang

“…In multiple regression analysis after controlling for confounders, only fasting blood glucose (β=5.615, P<0.001) and high-density lipoprotein cholesterol (β=19.483, P<0.001) were independently related to serum irisin. …”
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Low-Protein Diet Supplemented with Keto Acids Is Associated with Suppression of Small-Solute Peritoneal Transport Rate in Peritoneal Dialysis Patients by Na Jiang, Jiaqi Qian, Aiwu Lin, Wei Fang, Weiming Zhang, Liou Cao, Qin Wang, Zhaohui Ni, Qiang Yao

“…While baseline D/Pcr (dialysate-to-plasma concentration ratio for creatinine at 4 hour) and D/D0glu (dialysate glucose at 4 hour to baseline dialysate glucose concentration ratio) were similar, D/Pcr in group sLP was lower, and D/D0glu was higher than those in the other two groups (P<0.05) at 12th month. …”
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