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1161
The Impact of Incretin-Based Medications on Lipid Metabolism
Published 2021-01-01“…While the impact of incretins on glucose metabolism is clear, recent evidence indicates their positive modulatory roles on various aspects of lipid metabolism. …”
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1162
Group 2 Innate Lymphoid Cells Participate in Renal Fibrosis in Diabetic Kidney Disease Partly via TGF-β1 Signal Pathway
Published 2019-01-01“…However, compared with high-glucose stimulation alone, the expression of TGF-β1, FN, and collagen1 was significantly increased in HK-2 cells induced by high glucose combined with IL-4 or IL-13 (P<0.05). …”
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1163
Effect of gonadectomy and estradiol on the expression of insulin signaling cascade genes in female and male mice
Published 2020-07-01“…Estradiol levels were lower and glucose blood levels and insulin resistance were higher in Sham operated (Sham) males compared to Sham females. …”
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1164
PTPN2 Downregulation Is Associated with Albuminuria and Vitamin D Receptor Deficiency in Type 2 Diabetes Mellitus
Published 2018-01-01“…THP-1 cells were incubated with high glucose and further treated with or without paricalcitol, a vitamin D analog. …”
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1165
Role of transforming growth factor-β1 in regulating adipocyte progenitors
Published 2025-01-01“…We used CD206CreERT2; Tgf-β1f/f mouse model in which the Tgf-β1 gene was conditionally deleted in CD206+ M2-like macrophages followed by tamoxifen administration, to investigate the role of the Tgf-β1 gene in glucose and insulin metabolism. Our data demonstrated that lack of CD206+ M2-like macrophages derived Tgf-β1 gene improved glucose metabolism and insulin sensitivity by enhancing adipogenesis via hyperplasia. …”
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1166
Microbial community succession characteristics in an anaerobic baffled reactor during phenol gradient acclimation
Published 2025-03-01“…The pH levels in the first chamber fluctuated from 5.0 to 6.8 with glucose alone and increased with phenol addition. …”
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1167
High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome
Published 2021-01-01“…Asprosin, a new adipocytokine, has reportedly been associated with glucose release, dyslipidemia, and insulin resistance (IR). …”
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1168
Metabolism: A Novel Shared Link between Diabetes Mellitus and Alzheimer’s Disease
Published 2020-01-01“…We conclude from the published literature that the body’s diabetic status under certain circumstances such as metabolic abnormalities can increase the incidence of AD by affecting glucose transport to the brain and reducing glucose metabolism. …”
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1169
Tacrolimus Protects Podocytes from Apoptosis via Downregulation of TRPC6 in Diabetic Nephropathy
Published 2021-01-01“…The transient receptor potential channel 6 (TRPC6) is expressed in podocytes and mediates podocyte injury induced by high glucose levels. Tacrolimus is a novel immunosuppressive agent that is reported to play an important role in podocyte protection. …”
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1170
Clinical benefits of central pancreatectomy for a patient with pancreatic schwannoma and diabetes
Published 2025-01-01“…Meanwhile, the patient had type 2 diabetes and the blood glucose was controlled at 8-15mmol/L by taking oral antidiabetic drugs. …”
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1171
Maternal prediabetes as a risk factor of preeclampsia and placental dysfunction in pregnant female Sprague-Dawley rats
Published 2024-12-01“…Values of p < .05 were used to indicate statistical significance.Results Maternal PD and PE significantly increased blood glucose, decrease NO concentration and increase in MAP by comparison to the normal pregnant control group. …”
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1172
Extended High Frequency Audiometry in Polycystic Ovary Syndrome
Published 2013-01-01“…Insulin resistance, dyslipidemia, glucose intolerance, hypertension, and obesity are metabolic disorders accompanying the syndrome. …”
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1173
PPAR-α regulates metabolic remodelling and participates in myocardial fibrosis in patients with atrial fibrillation of rheumatic heart disease
Published 2024-07-01“…PPAR-α may participate in the pathogenesis of myocardial fibrosis in rheumatic heart disease AF by regulating glucose metabolism, lipid metabolism, and mitochondrial function.…”
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1174
Maternal Rat Diabetes Mellitus Deleteriously Affects Insulin Sensitivity and Beta-Cell Function in the Offspring
Published 2013-01-01“…This study was designed to assess the effect of maternal diabetes in rats on serum glucose and insulin concentrations, insulin resistance, histological architecture of pancreas and glycogen content in liver of offspring. …”
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1175
DIABETES MELLITUS IN PATIENTS WITH LIVER CIRRHOSIS: NEW TREATMENT OPTIONS
Published 2017-09-01“…About 80% of patients with LC may have impaired glucose metabolism, and 30% have diabetes mellitus. …”
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1176
High prevalence of prediabetes and type 2 diabetes, and identification of associated factors, in high-risk adults in Vietnam: A cross-sectional study
Published 2025-01-01“…The diagnosis of prediabetes and diabetes relied on measurements of fasting plasma glucose, HbA1c, and 2-hour plasma glucose after a 75 g oral glucose tolerance test. …”
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1177
Gypenoside ameliorates insulin resistance and hyperglycemia via the AMPK-mediated signaling pathways in the liver of type 2 diabetes mellitus mice
Published 2022-09-01“…Gps reduced fasting blood glucose and serum lipids, as well as significantly improved T2DM mice glucose tolerance and insulin resistance (IR). …”
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1178
Lipotoxicity and metabolic disorders at obesity
Published 2010-02-01“…In this aspect it is necessary to focus on glitazones (PPARs ligands), metformin among pharmacological substances, which has no influence on insulin secretion, however it has a lot of extrapancreatic effects by which it reduces increased concentrations of glucose in blood, improves tissue sensitivity to insulin and, thus, increases uptake of glucose by liver and muscles cells. …”
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1179
Baicalein inhibits NLRP3 inflammasome activation and mitigates placental inflammation and oxidative stress in gestational diabetes mellitus
Published 2024-12-01“…In this study, we found that Baicalein ameliorates metabolic disturbances in GDM mice by improving glucose tolerance, insulin sensitivity, fasting blood glucose levels, and plasma insulin levels. …”
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1180
Beneficial Effects of Poplar Buds on Hyperglycemia, Dyslipidemia, Oxidative Stress, and Inflammation in Streptozotocin-Induced Type-2 Diabetes
Published 2018-01-01“…The effects of propolis on blood glucose regulation and the alleviation of various complications caused by diabetes have been widely studied. …”
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